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1. 发明授权

EP1658872B2 Powder inhaler 有权转让
公开(公告)号：EP1658872B2
公开(公告)日：2019-08-21
申请号：EP06003929.4
申请日：2002-07-31
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： Pinon, John , Shirgaonkar, Sameer , Smith, Christopher James , Burge, Simon , Middleton, Max William , Ahern, David , Sarkar, Matthew Neil , Arlett, Ben , Lye, Emma Lesley , Smith, Simon
IPC分类号： A61M15/00

2. 发明公开

EP1386630A1 Powder inhaler 有权
标题翻译： Pulverinhalator
公开(公告)号：EP1386630A1
公开(公告)日：2004-02-04
申请号：EP02016908.2
申请日：2002-07-31
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： Pinon, John , Shirgaonkar, Sameer , Smith, Christopher James , Burge, Simon , Middleton, Max William , Ahern, David , Sarkar, Matthew Neil , Arlett, Ben , Lye, Emma Lesley , Smith, Simon
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248
摘要： A powder inhaler comprises a container (7) for storing a powdered medicament, a metering member (15) having a dosing recess (18) to be filled with a dose of the powdered medicament, and a mouthpiece (3) being in communication with an inhalation channel (27) of the powder inhaler. Furthermore, the powder inhaler comprises a protective member (19) which is slidingly moveable on the metering member (15) between a closed position, in which it at least covers the dosing recess (18) of the metering member (15) if the metering member (15) is in an inhalation position, and an open position, in which it exposes the dosing recess (18) thereby enabling inhalation of the dose of the powdered medicament contained in the dosing recess (18). The protective member (19) is preferably coupled to an inhalation actuated mechanism (21-23) in such a manner that the inhalation actuated mechanism (21-23) moves the protective member (19) from its closed position to its open position only if there is an inhalation suction force exerted by a user which exceeds a predetermined level. This prevents the dose contained in the dosing recess (18) from falling out of the dosing recess, unless there is no inhalation process initiated by the user. Therefore, the powder inhaler can also be operated reliably upside down. Furthermore, a deagglomerator arrangement (cyclone), which may be incorporated in such a powder inhaler, is proposed which comprises a vortex chamber (73) having a diameter between 6 mm and 8 mm, preferably 8 mm.
摘要翻译：粉末吸入器包括用于储存粉末药物的容器（7），具有待填充剂量的粉末药物的剂量凹槽（18）的计量构件（15），以及与一个粉末吸入器的吸入通道（27）。此外，粉末吸入器包括保护构件（19），该保护构件可在计量构件（15）之间在关闭位置之间滑动移动，在闭合位置，如果计量构件（15）至少覆盖计量构件（15）的计量凹部（18）构件（15）处于吸入位置和打开位置，在所述打开位置中，所述打开位置暴露所述计量凹部（18），由此能够吸入所述剂量凹部（18）中所含的粉末状药物的剂量。优选地，保护构件（19）以吸入致动机构（21-23）联接到吸入致动机构（21-23），使得吸入致动机构（21-23）仅当保护构件（19）从其关闭位置移动到其打开位置时存在超过预定水平的用户施加的吸入吸力。这防止剂量凹陷（18）中包含的剂量从剂量凹槽中脱落，除非由用户发起吸入过程。因此，粉末吸入器也可以可靠地上下颠倒地操作。此外，提出了可以结合在这种粉末吸入器中的解聚器装置（旋风分离器），其包括直径在6mm和8mm之间，优选8mm的涡流室（73）。

3. 发明授权

EP1386630B1 Powder inhaler 有权
标题翻译：干粉吸入器
公开(公告)号：EP1386630B1
公开(公告)日：2006-05-17
申请号：EP02016908.2
申请日：2002-07-31
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： Pinon, John , Shirgaonkar, Sameer , Smith, Christopher James , Burge, Simon , Middleton, Max William , Ahern, David , Sarkar, Matthew Neil , Arlett, Ben , Lye, Emma Lesley , Smith, Simon
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248

4. 发明授权

EP1658872B1 Powder inhaler 有权转让
标题翻译：干粉吸入器
公开(公告)号：EP1658872B1
公开(公告)日：2011-03-30
申请号：EP06003929.4
申请日：2002-07-31
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： Pinon, John , Shirgaonkar, Sameer , Smith, Christopher James , Burge, Simon , Middleton, Max William , Ahern, David , Sarkar, Matthew Neil , Arlett, Ben , Lye, Emma Lesley , Smith, Simon
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248
摘要： A powder inhaler comprises a container (7) for storing a powdered medicament, a metering member (15) having a dosing recess (18) to be filled with a dose of the powdered medicament, and a mouthpiece (3) being in communication with an inhalation channel (27) of the powder inhaler. Furthermore, the powder inhaler comprises a protective member (19) which is slidingly moveable on the metering member (15) between a closed position, in which it at least covers the dosing recess (18) of the metering member (15) if the metering member (15) is in an inhalation position, and an open position, in which it exposes the dosing recess (18) thereby enabling inhalation of the dose of the powdered medicament contained in the dosing recess (18). The protective member (19) is preferably coupled to an inhalation actuated mechanism (21-23) in such a manner that the inhalation actuated mechanism (21-23) moves the protective member (19) from its closed position to its open position only if there is an inhalation suction force exerted by a user which exceeds a predetermined level. This prevents the dose contained in the dosing recess (18) from falling out of the dosing recess, unless there is no inhalation process initiated by the user. Therefore, the powder inhaler can also be operated reliably upside down. Furthermore, a deagglomerator arrangement (cyclone), which may be incorporated in such a powder inhaler, is proposed which comprises a vortex chamber (73) having a diameter between 6 mm and 8 mm, preferably 8 mm.

5. 发明公开

EP1658872A3 Powder inhaler 有权转让
标题翻译：粉末吸入器
公开(公告)号：EP1658872A3
公开(公告)日：2007-01-03
申请号：EP06003929.4
申请日：2002-07-31
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： Pinon, John , Shirgaonkar, Sameer , Smith, Christopher James , Burge, Simon , Middleton, Max William , Ahern, David , Sarkar, Matthew Neil , Arlett, Ben , Lye, Emma Lesley , Smith, Simon
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248
摘要： Deagglomerator arrangement (16), for deagglomerating a powdered medicament, comprising:
a vortex chamber (73) having an opening for the supply of the powdered medicament,
at least one air inlet (75) for directing air tangentially into the vortex chamber (73), and
an outlet (74) for outputting air with the deagglomerated powdered medicament, the outlet (74) being spaced from the at least one air inlet (75) in an axial direction of the deagglomerator arrangement (16),
characterized in that
the vortex chamber (73) has a diameter d of 6 mm ≤ d ≤ 10 mm.
摘要翻译：包括：具有用于供应粉状药剂的开口的涡流室（73），用于将空气切向引导到涡流室（73）中的至少一个空气入口（75），用于将粉末状药物散开的粉碎装置（16），以及用于用所述解聚集的粉状药剂输出空气的出口（74），所述出口（74）沿所述解聚器装置（16）的轴向方向与所述至少一个空气入口（75）间隔开，其特征在于，所述涡流腔室（73）具有6mm≤d≤10mm的直径d。

6. 发明公开

EP1658872A2 Powder inhaler 有权转让
标题翻译： Pulverinhalator
公开(公告)号：EP1658872A2
公开(公告)日：2006-05-24
申请号：EP06003929.4
申请日：2002-07-31
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： Pinon, John , Shirgaonkar, Sameer , Smith, Christopher James , Burge, Simon , Middleton, Max William , Ahern, David , Sarkar, Matthew Neil , Arlett, Ben , Lye, Emma Lesley , Smith, Simon
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0026 , A61M15/0075 , A61M2202/062 , A61M2202/064 , A61M2206/16 , G06M1/04 , G06M1/045 , G06M1/248
摘要： Deagglomerator arrangement (16), for deagglomerating a powdered medicament, comprising:
a vortex chamber (73) having an opening for the supply of the powdered medicament,
at least one air inlet (75) for directing air tangentially into the vortex chamber (73), and
an outlet (74) for outputting air with the deagglomerated powdered medicament, the outlet (74) being spaced from the at least one air inlet (75) in an axial direction of the deagglomerator arrangement (16),
characterized in that
the vortex chamber (73) has a diameter d of 6 mm ≤ d ≤ 10 mm.
摘要翻译：用于解散粉末状药物的分散器装置（16），包括：具有用于供应粉末药物的开口的涡流室（73），用于将空气切向地引导到涡流室（73）中的至少一个空气入口（75），以及用于与所述解聚粉末药物一起输出空气的出口（74），所述出口（74）沿所述解聚集装置（16）的轴向方向与所述至少一个空气入口（75）间隔开，其特征在于，所述涡流室（73）的直径d为6 mm‰¤d‰¤10 mm。

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