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1. 发明公开

EP2593164A1 FILTERSYSTEM FÜR DEN EINSATZ IN MEDIZINISCHEN GERÄTEN 有权
标题翻译：过滤系统使用医疗器械
公开(公告)号：EP2593164A1
公开(公告)日：2013-05-22
申请号：EP11730632.4
申请日：2011-07-05
申请人： Boehringer Ingelheim International GmbH
发明人： HAUSMANN, Matthias , SCHUY, Steffen , EICHER, Joachim , GESER, Johannes , MEISENHEIMER, Martin , WITTE, Florian
IPC分类号： A61M11/02 , A61M11/06 , A61M15/00 , B05B1/00 , B05B11/00
CPC分类号： A61M11/003 , A61M11/00 , A61M11/007 , A61M11/02 , A61M11/06 , A61M15/009 , A61M2205/7545 , A61M2205/8281 , A61M2207/00 , B05B11/0043 , B05B11/3001 , B05B11/308 , B05B11/3091 , Y10T29/49826
摘要： The invention relates to a medical hand-held device, in particular an atomizer (1), for dispensing a liquid pharmaceutical preparation from a container. The pharmaceutical preparation can be based, for example, on an alcoholic solvent. The proposed atomizer has a discharge nozzle for the pharmaceutical preparation. Located upstream from the discharge nozzle (12d, 12e) there is a multiple-stage filter system, which is composed of at least three filtering components (27, 28, 12f). The filters differ from one another in terms of their filter threshold and their filter materials and/or filter effect. In particular, the use of a filter made of sintered metal is proposed in order to avoid penetration of particles into a microstructured component (12), which can also contain a very fine filter in front of the nozzle. Alternatively or in addition, it is also proposed to use an adsorption filter in the flow path between a coarse filter and the microstructured component.

2. 发明授权

EP1346212B1 VERFAHREN UND VORRICHTUNG ZUM PRÜFEN VON MEHRSCHICHTFOLIEN UND DARAUS HERSGESTELLTEN BEHÄLTERN 有权
标题翻译：方法和设备测试复合膜和制品HERSGESTELLTEN集装箱
公开(公告)号：EP1346212B1
公开(公告)日：2006-03-29
申请号：EP01988021.0
申请日：2001-12-13
申请人： Boehringer Ingelheim International GmbH
发明人： HENNING, Carsten , WITTEKIND, Jürgen , KLADDERS, Heinrich , HAUSMANN, Matthias , KÜHNEL, Andreas , RENGEL, Heiko
IPC分类号： G01N27/66
CPC分类号： G01N27/205
摘要： The invention relates to a method and a device for detecting gas-permeable damage points in an electrically non-conductive layer which can be embodied as a single layer or a multi-layered composite comprising at least one conductive layer. A test piece is arranged in a test chamber. The layer which is to be tested has an electrically conductive layer on the one side and a gas chamber on the other side. The gas in the gas chamber is ionised at a pre-defined low pressure by means of an electric gas discharge. A counter electrode which is arranged in the gas chamber forms a test current circuit with a voltage source and a measuring device. If the layer which is to be tested contains a damage point, the gas discharge is maintained and a direct current is measured in the test current circuit, said current acting as an indicator for a damage point. Due to said method, it is possible to detect damage points are liquid tight or which are only present in a non-conductive layer in a multi-layered composite. The inventive method is used in containers for sensitive pharmaceutical preparations, if the containers are subjected to exacting requirements with regard to the impermability thereof during a storage period or application period lasting several months.

3. 发明授权

EP1156769B1 KARTUSCHE FÜR EINE FLÜSSIGKEIT 有权
标题翻译：墨盒液体
公开(公告)号：EP1156769B1
公开(公告)日：2004-09-29
申请号：EP00912465.2
申请日：2000-02-16
申请人： Boehringer Ingelheim International GmbH
发明人： KLADDERS, Heinrich , ZIERENBERG, Bernd , HOCHRAINER, Dieter , EICHER, Joachim , HAUSMANN, Matthias , WUTTKE, Gilbert , SCHYRA, Michael , FIOL, Andreas , GESER, Johannes
IPC分类号： A61J1/00
CPC分类号： B05B11/0054 , A61M15/0065 , B05B11/0008 , B05B11/0016 , B05B11/0021 , B05B11/0024 , B05B11/0043
摘要： A practically diffusion-tight container which is capable of being stored over long periods of time and with which the liquid does not come into contact with the ambient air is required for withdrawing a liquid in a dosed manner out of the same over a duration of several months. The inventive cartridge is a container which is comprised of three shells and which can consist of a collapsible bag containing the liquid, of a dimensionally stabile container, and of a stiff metal shell. The cartridge can be detachably connected to a withdrawing device. The cartridge can be provided with a micro-opening with which the time for the pressure compensation between the cartridge and the surroundings can be adjusted. The cartridge is suited for aqueous and alcoholic liquids which contain a pharmacologically active ingredient. The liquid in the cartridge is protected against external influences. The cartridge can be used in an atomizer for generating an aerosol which can be inhaled and which is provided for treating illnesses.

4. 发明授权

EP2453961B1 HOCHDRUCKKAMMER 有权
标题翻译：高压室
公开(公告)号：EP2453961B1
公开(公告)日：2017-11-08
申请号：EP10724801.5
申请日：2010-06-07
申请人： Boehringer Ingelheim International GmbH
发明人： HAUSMANN, Matthias , WABNITZ, Thomas
IPC分类号： A61M11/02 , A61M11/06 , A61M15/00 , B05B1/00 , B05B11/00 , B05B15/00 , A61B17/3203
CPC分类号： A61M15/009 , A61B17/3203 , A61M11/02 , A61M11/06 , A61M15/0035 , A61M2205/7545 , A61M2205/8281 , B05B1/00 , B05B11/3001 , B05B11/3015 , B05B11/3042 , B05B11/3091 , B05B15/40 , Y10T29/49826 , Y10T29/49908

5. 发明授权

EP3407944B1 NEBULIZER 有权
公开(公告)号：EP3407944B1
公开(公告)日：2019-12-11
申请号：EP17702314.0
申请日：2017-01-20
申请人： Boehringer Ingelheim International GmbH
发明人： KLADDERS, Heinrich , HAUSMANN, Matthias
IPC分类号： A61M11/00 , A61M15/00

6. 发明授权

EP1893343B1 NEBULISER AND CONTAINER 有权转让
标题翻译：雾化器和集装箱
公开(公告)号：EP1893343B1
公开(公告)日：2014-10-15
申请号：EP06762147.4
申请日：2006-06-23
申请人： Boehringer Ingelheim International GmbH
发明人： KUNZE, Hubert , HAUSMANN, Matthias , BESSELER, Jens , HENNING, Carsten , KLADDERS, Heinrich , MAST, Markus , LANCI, Antonino , DWORZAK, Christoph , MOCK, Elmar , WITTE, Florian , GESER, Johannnes
IPC分类号： B05B11/00 , B65D83/14
CPC分类号： B05B11/3091 , B05B11/0016 , B05B11/0054 , B05B11/3001

7. 发明公开

EP2254704A1 RESERVOIR AND NEBULIZER 有权
标题翻译：坦克和雾化器
公开(公告)号：EP2254704A1
公开(公告)日：2010-12-01
申请号：EP09723193.0
申请日：2009-03-06
申请人： Boehringer Ingelheim International GmbH
发明人： HAUSMANN, Matthias , SCHMIEDEL, Guido , WITTE, Florian , GESER, Johannes , MATHE, Gerald , MEISENHEIMER, Martin , LANCI, Antonio , MOCK, Elmar , SIGRIST, Martin , HOLOAKOVSKY, Holger
IPC分类号： B05B11/00
CPC分类号： A61M11/02 , A61M11/007 , A61M11/08 , A61M15/0021 , A61M15/0035 , A61M15/0065 , A61M2202/0468 , A61M2205/123 , B05B11/0016 , B05B11/0024 , B05B11/0037 , B05B11/0043 , B05B11/3061 , B05B11/3091
摘要： A reservoir (3) for a nebulizer (1), a nebulizer (1) and a method of filling a reservoir (3) are proposed. To avoid undesirable rises in pressure, a fluid chamber (4) of the reservoir (3) is pre-collapsed and filled with an initial amount of fluid (2) which is less than the maximum volume of the fluid chamber (4). Preferably, before being filled, the fluid chamber (4) is compressed and/or expanded by means of gas to a defined volume which is less than the maximum volume of the fluid chamber (4).

8. 发明公开

EP1706210A1 VORRICHTUNG ZUM HALTERN EINES FLUIDISCHEN BAUTEILS 有权
标题翻译： DEVICE FOR A流体组件的持有者
公开(公告)号：EP1706210A1
公开(公告)日：2006-10-04
申请号：EP04804353.3
申请日：2004-12-28
申请人： Boehringer Ingelheim International GmbH
发明人： GESER, Johannes , HAUSMANN, Matthias
IPC分类号： B05B1/00
CPC分类号： B05B1/00 , Y10T29/49826
摘要： Special precautions must be taken when maintaining a component under fluidic pressure, if the component consists of hard and brittle material and can be destroyed by locally increased stresses. According to the invention, one such fluidic component, e.g. consisting of silicon or glass, is arranged in an elastomer mould, e.g. consisting of silicon rubber, having a contour that is adapted to the outer contour of the component and to the inner contour of a support. Said elastomer mould is bevelled on the pressure side thereof towards the fluidic component. During the assembly of the support, the elastomer mould is deformed by means of a projection on the counterpart, and subjected to homogeneously distributed inner stress, whereafter the elastomer mould surrounds the fluidic component over the entire height thereof. Said floating support prevents any unacceptable local stress peaks and any deformation of the component. The support is sealed from the fluid, even if the fluidic pressure fluctuates repeatedly from a very small value to several hundred bar. The support is especially suitable for a fluidic component consisting of glass or silicon in a miniature embodiment. Said support is used in the field of medical technology, for example, for a nozzle in a miniature atomiser for producing an aerosol or a mist without a propellant, and for the needleless subcutaneous injection of a liquid containing a medically active substance.

9. 发明授权

EP1126922B1 DRUCKAUSGLEICHSVORRICHTUNG FÜR EINEN DOPPELBEHÄLTER 有权
标题翻译：压力补偿装置对于双TANK
公开(公告)号：EP1126922B1
公开(公告)日：2006-04-26
申请号：EP99957289.4
申请日：1999-11-08
申请人： Boehringer Ingelheim International GmbH
发明人： HOCHRAINER, Dieter , KLADDERS, Heinrich , ZIERENBERG, Bernd , EICHER, Joachim , ESSING, Martin , HAUSMANN, Matthias , WUTTKE, Gilbert
IPC分类号： B05B11/00 , B65D83/00
CPC分类号： B05B11/0021 , B05B11/0016 , B05B11/0024 , B05B11/0043 , B65D83/0055
摘要： Dual containers, consisting of an inner container (2) and a diffusion-tight outer container (1) are used for medical fluids. The inner container collapses when the fluid is removed. A pressure-compensating device is required to compensate the pressure between the gas chamber (15) that is located between the inner and outer container and the surrounding area of the dual container, whereby the loss of fluid is kept to a minimum by diffusion from the collapsible inner container. At least one duct (7) that links the gas-filled space to the surrounding area of the dual container is used for this purpose. The time constant for compensation of a pressure differential of several millibars is several hours. This is achieved by selecting the length of the duct and cross section thereof. The at least one duct can be produced individually or a plurality of ducts can be provided in the form of pores in an open-pored sintered material or a permeable membrane. The pressure-compensating device enables the dual container to be stored for years and, if the fluid is removed in portions in a correct manner, it can be used for several weeks. During these periods, the amount of liquid in the inner container or the concentration thereof varies substantially less than if a dual container known per se is used.

10. 发明公开

EP1126922A1 DRUCKAUSGLEICHSVORRICHTUNG FÜR EINEN DOPPELBEHÄLTER 有权
标题翻译：压力补偿装置对于双TANK
公开(公告)号：EP1126922A1
公开(公告)日：2001-08-29
申请号：EP99957289.4
申请日：1999-11-08
申请人： Boehringer Ingelheim International GmbH
发明人： HOCHRAINER, Dieter , KLADDERS, Heinrich , ZIERENBERG, Bernd , EICHER, Joachim , ESSING, Martin , HAUSMANN, Matthias , WUTTKE, Gilbert
IPC分类号： B05B11/00 , B65D83/00
CPC分类号： B05B11/0021 , B05B11/0016 , B05B11/0024 , B05B11/0043 , B65D83/0055
摘要： Dual containers, consisting of an inner container (2) and a diffusion-tight outer container (1) are used for medical fluids. The inner container collapses when the fluid is removed. A pressure-compensating device is required to compensate the pressure between the gas chamber (15) that is located between the inner and outer container and the surrounding area of the dual container, whereby the loss of fluid is kept to a minimum by diffusion from the collapsible inner container. At least one duct (7) that links the gas-filled space to the surrounding area of the dual container is used for this purpose. The time constant for compensation of a pressure differential of several millibars is several hours. This is achieved by selecting the length of the duct and cross section thereof. The at least one duct can be produced individually or a plurality of ducts can be provided in the form of pores in an open-pored sintered material or a permeable membrane. The pressure-compensating device enables the dual container to be stored for years and, if the fluid is removed in portions in a correct manner, it can be used for several weeks. During these periods, the amount of liquid in the inner container or the concentration thereof varies substantially less than if a dual container known per se is used.

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