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1. 发明授权

EP2572710B1 NOVEL USE OF PANDURATIN DERIVATIVES OR AN EXTRACT OF BOESENBERGIA PANDURATA FOR PROMOTING MUSCLE MASS GROWTH, FIGHTING FATIGUE, AND ENHANCING EXERCISE PERFORMANCE CAPABILITY 有权转让
标题翻译：新的泛酸衍生物或硼砂提取物用于促进肌肉增长，减缓疲劳，提高运动能力
公开(公告)号：EP2572710B1
公开(公告)日：2018-04-11
申请号：EP11783791.4
申请日：2011-05-20
申请人： Biocare Co., Ltd. , NEWTREE CO., LTD.
发明人： HWANG, Jae-Kwan , KIM, Do Un
IPC分类号： A61P43/00 , A61P21/00 , A61K31/05 , A61K36/906
CPC分类号： A61K36/906 , A23L33/105 , A61K31/12 , A61K36/00
摘要： The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for enhancing muscle mass growth, fighting fatigue and enhancing exercise performance, and more particularly to a composition for promoting an increase in muscles, anti-fatigue composition and a composition for enhancing muscle mass growth and recovery from fatigue to improve exercise performance, the composition comprising a panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata as an active ingredient, and to a method for enhancing muscle mass growth, of treating or preventing fatigue syndrome and enhancing exercise performance, the method comprising a panduratin derivative or a salt thereof or a extract of Boesenbergia pandurata to a subject in need thereof. A panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata of the present invention may be used without side effect and has the effect of increasing the expression of PPAR-´ in muscles to increase muscle mass, promoting recovery from fatigue and increase mobility, thereby improving exercise performance.

2. 发明授权

EP2200576B1 NOVEL USE OF LIGNAN-TYPE COMPOUNDS ISOLATED FROM EXTRACT OF NUTMEG OR ARIL OF NUTMEG 有权转让
标题翻译：新鲜的肉豆蔻或肉豆蔻提取物中分离的木脂素类化合物的新用途
公开(公告)号：EP2200576B1
公开(公告)日：2017-12-20
申请号：EP08839723.7
申请日：2008-10-17
申请人： Biocare Co., Ltd. , NEWTREE CO., LTD.
发明人： HWANG, Jae-Kwan , CHO, Yu-Mi , KIM, Gyu Hoi , KIM, Jeong Hwan , LEE, Hae Ji , OH, Hyun In , CHUNG, Hee Chul , CHUNG, Jae Youn , KIM, Do Un
IPC分类号： A61K8/49 , A61K8/97 , A61Q19/02 , A61K31/36 , A61K36/185
CPC分类号： A61Q19/02 , A61K8/4973 , A61K8/97 , A61K31/357 , A61K36/185
摘要： The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.

3. 发明公开

EP2572710A2 NOVEL USE OF PANDURATIN DERIVATIVES OR AN EXTRACT OF BOESENBERGIA PANDURATA FOR PROMOTING MUSCLE MASS GROWTH, FIGHTING FATIGUE, AND ENHANCING EXERCISE PERFORMANCE CAPABILITY 有权转让
标题翻译： PANDURATINDERIVATEN或摘录从提琴形凹唇蓬莪的新用途，促进肌肉生长，抗疲劳与提高培训能力
公开(公告)号：EP2572710A2
公开(公告)日：2013-03-27
申请号：EP11783791.4
申请日：2011-05-20
申请人： Biocare Co., Ltd. , NEWTREE CO., LTD.
发明人： HWANG, Jae-Kwan , KIM, Do Un
IPC分类号： A61K31/05 , A61K36/906 , A61P21/00 , A61P43/00
CPC分类号： A61K36/906 , A23L33/105 , A61K31/12 , A61K36/00
摘要： The present invention relates to the novel use of panduratin derivatives or an extract of Boesenbergia pandurata for enhancing muscle mass growth, fighting fatigue and enhancing exercise performance, and more particularly to a composition for promoting an increase in muscles, anti-fatigue composition and a composition for enhancing muscle mass growth and recovery from fatigue to improve exercise performance, the composition comprising a panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata as an active ingredient, and to a method for enhancing muscle mass growth, of treating or preventing fatigue syndrome and enhancing exercise performance, the method comprising a panduratin derivative or a salt thereof or a extract of Boesenbergia pandurata to a subject in need thereof. A panduratin derivative or a salt thereof or an extract of Boesenbergia pandurata of the present invention may be used without side effect and has the effect of increasing the expression of PPAR-δ in muscles to increase muscle mass, promoting recovery from fatigue and increase mobility, thereby improving exercise performance.
摘要翻译：本发明涉及的新用途因Panduratin衍生物或用于增强肌肉质量的增长，战斗疲劳，增强运动性能提取提琴形凹唇蓬莪的，并且更具体地涉及一种组合物，用于促销廷在肌肉，抗疲劳组合物和组合物增加用于增强肌肉质量的生长和恢复疲劳，提高运动性能，该组合物包含Panduratin衍生物或或其盐以提取提琴形凹唇蓬莪的作为活性成分的，以及用于增强肌肉质量的生长，治疗或预防疲劳的方法综合征和增强运动性能，所述方法包括一个Panduratin衍生物或其盐或提琴形凹唇蓬莪的向需要其的受试者的提取物。甲Panduratin衍生物或其盐或以提取本发明的提琴形凹唇蓬莪的可无副作用使用，且在肌肉增加PPAR”的表达，从而增加肌肉质量，促销廷恢复疲劳，提高流动性的效果，从而提高运动表现。

4. 发明公开

EP2200576A2 NOVEL USE OF LIGNAN-TYPE COMPOUNDS OR EXTRACT OF NUTMEG OR ARIL OF NUTMEG COMPRISING THE SAME 有权转让
标题翻译： NEUE VERWENDUNG VON AUS MUSKATEXTRAKT ODER MUSKATARILLUS EXTRAKT ISOLIERTEN LIGNANVERBINDUNGEN
公开(公告)号：EP2200576A2
公开(公告)日：2010-06-30
申请号：EP08839723.7
申请日：2008-10-17
申请人： Biocare Co., Ltd. , NEWTREE CO., LTD.
发明人： HWANG, Jae-Kwan , CHO, Yu-Mi , KIM, Gyu Hoi , KIM, Jeong Hwan , LEE, Hae Ji , OH, Hyun In , CHUNG, Hee Chul , CHUNG, Jae Youn , KIM, Do Un
IPC分类号： A61K8/49
CPC分类号： A61Q19/02 , A61K8/4973 , A61K8/97 , A61K31/357 , A61K36/185
摘要： The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.
摘要翻译：本发明涉及木质素型化合物或含有该木素素类化合物的肉豆蔻或肉豆蔻酸的提取物的新用途。更具体地，本发明涉及一种皮肤美白组合物，其包含木素素型化合物或包含该组合物的肉豆蔻或肉豆蔻的提取物。由于化学式1〜3所示的木酚素化合物或肉豆蔻肉豆蔻酸的提取物通过抑制黑色素生成和酪氨酸酶活性而具有优异的皮肤美白活性，因此可用于制备化妆品组合物，食品组合物或药物组合物用于皮肤美白。

5. 发明公开

EP2351559A2 NOVEL USE OF PANDURATIN DERIVATIVE OR BOESENBERGIA PANDURATA EXTRACT 有权转让
标题翻译： NEER VERWENDUNG EINES PANDURATIN-DERIVATS ODER BOESENBERGIA PANDURATA-EXTRAKTS
公开(公告)号：EP2351559A2
公开(公告)日：2011-08-03
申请号：EP09819415.2
申请日：2009-10-09
申请人： NEWTREE CO., LTD. , Hwang, Jae-Kwan
发明人： HWANG, Jae-Kwan , KIM, Do Un
IPC分类号： A61K31/05 , A61K36/906 , A61P3/04 , A23L1/29
CPC分类号： A23C9/152 , A23L2/02 , A23L2/52 , A23L13/67 , A23L23/00 , A23L33/105 , A23L33/30 , A61K31/121 , A61K36/906
摘要： The present invention relates to a novel use of a panduratin derivative or a Boesenbergia pandurata extract. More specifically, the invention relates to a composition for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, containing a panduratin derivative represented by Chemical Formula 1, 2 or 3 or a Boesenbergia pandurata extract as an active ingredient, a method for treating a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, by administering an effective amount of the panduratin derivative or the Boesenbergia pandurata extract to a subject in need thereof, and a use of the panduratin derivative or the Boesenbergia pandurata extract to prepare a reagent for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes. As can be seen foregoing, the present invention provides a novel use of a panduratin derivative or a Boesenbergia pandurata extract. A panduratin derivative or a Boesenbergia pandurata extract of the present invention shows excellent effects on a metabolic disease such as obesity, hyperlipidemia, hypercholesterolemia and diabetes by decreasing highly related causes of metabolic diseases such as on weight, body fat and lipid-content. Since a composition of the present invention is originated from natural materials, it can be used without side effect and provides novel method for preventing and treating/relieving a metabolic disease through body weight loss and body fat loss and the like.
摘要翻译：本发明涉及一种潘多汀衍生物或蒲公英提取物的新用途。更具体地说，本发明涉及含有由化学式1,2或3表示的潘多肽衍生物或者一种Boesenbergia pandurata提取物的预防和治疗选自肥胖症，高脂血症，高胆固醇血症和糖尿病的代谢疾病的组合物作为活性成分，可以通过向有需要的受试者施用有效量的潘多汀衍生物或Boesenbergia pandurata提取物来治疗选自肥胖症，高脂血症，高胆固醇血症和糖尿病的代谢疾病的方法，以及使用的潘多汀衍生物或Boesenbergia pandurata提取物，以制备用于预防和治疗或减轻选自肥胖症，高脂血症，高胆固醇血症和糖尿病的代谢疾病的试剂。从前面可以看出，本发明提供了一种潘多汀衍生物或一种Boesenbergia pandurata提取物的新用途。本发明的潘多林衍生物或泛黄柏提取物通过降低代谢性疾病如重量，体脂肪和脂质含量的高度相关原因，对肥胖症，高脂血症，高胆固醇血症和糖尿病等代谢疾病表现出优异的效果。由于本发明的组合物来自天然材料，因此可以无副作用地使用，并且通过体重减轻和身体脂肪减少等提供预防和治疗/减轻代谢疾病的新方法。

6. 发明授权

EP2200574B1 NOVEL USE OF PANDURATIN DERIVATIVES OR EXTRACT OF KAEMPFERIA PANDURATA COMPRISING THE SAME 有权
公开(公告)号：EP2200574B1
公开(公告)日：2019-06-26
申请号：EP08840361.3
申请日：2008-10-17
申请人： NEWTREE CO., LTD.
发明人： HWANG, Jae-Kwan , SHIM, Jae-Seok , GWON, Song Hui , KWON, Yi Young , OH, Hyun In , HAN, Young Sun , CHOI, Eun Jung , KIM, Do Un
IPC分类号： A61K8/35 , A61Q19/08 , A61K8/97

7. 发明授权

EP2170255B1 USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT 有权转让
公开(公告)号：EP2170255B1
公开(公告)日：2019-11-27
申请号：EP08766506.3
申请日：2008-06-20
申请人： AAT Costech Co., Ltd. , NEWTREE CO., LTD.
发明人： HWANG, Jae-Kwan , LEE, Hae Ji , LEE, Jae Young , SHIM, Jae-Seok , KIM, Jeong Hwan , KIM, Do Un , CHUNG, Heechul , CHUNG, Jae Youn
IPC分类号： A61K8/34 , A61K8/49 , A61K8/9789 , A61Q19/08

8. 发明授权

EP2351559B1 NOVEL USE OF PANDURATIN DERIVATIVE OR BOESENBERGIA PANDURATA EXTRACT 有权转让
标题翻译：潘多汀衍生物或提琴形凹唇蓬莪萃取物的新用途
公开(公告)号：EP2351559B1
公开(公告)日：2015-08-12
申请号：EP09819415.2
申请日：2009-10-09
申请人： NEWTREE CO., LTD. , Hwang, Jae-Kwan
发明人： HWANG, Jae-Kwan , KIM, Do Un
IPC分类号： A61K31/05 , A61K36/906 , A61P3/04 , A23L1/29 , A61K31/121 , A61P3/06 , A61P3/10
CPC分类号： A23C9/152 , A23L2/02 , A23L2/52 , A23L13/67 , A23L23/00 , A23L33/105 , A23L33/30 , A61K31/121 , A61K36/906

9. 发明公开

EP2170255A2 USE OF LIGNAN COMPOUND FOR ANTI-WRINKLE TREATMENT 有权转让
标题翻译：使用木脂素连接对于治疗皱纹
公开(公告)号：EP2170255A2
公开(公告)日：2010-04-07
申请号：EP08766506.3
申请日：2008-06-20
申请人： Biocare CO., LTD. , Hwang, Jae-Kwan
发明人： HWANG, Jae-Kwan , LEE, Hae Ji , LEE, Jae Young , SHIM, Jae-Seok , KIM, Jeong Hwan
IPC分类号： A61K8/34
摘要： The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme-1 (MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.

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