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    • 6. 发明公开
    • DRUG DELIVERY DEVICE FOR DRUG SUSPENSIONS
    • 用于药物悬浮液的药物递送装置
    • EP3284497A1
    • 2018-02-21
    • EP17193217.1
    • 2013-03-18
    • Becton, Dickinson and Company
    • GROSKOPF, Roger W.VEDRINE, LionelRATIGAN, Michael C.
    • A61M5/24A61M5/28A61M5/34
    • In one aspect of the subject invention, a drug delivery device is provided which includes a reservoir for containing a medicament and has a proximal end and a distal end, the medicament including a suspension of solids in a liquid carrier. Further, the drug delivery device includes a needle in fluid communication with the reservoir and having a distal end for injection into a patient, and a proximal end in the reservoir. An accumulation surface is defined at least partially about the needle, distally of the proximal end of the needle. The accumulation surface defines a distally-extending indentation which is sized and shaped to collect, during use, solids that come out of suspension. Advantageously, with the subject invention, the accumulation surface allows for solids to accumulate at a location spaced from the proximal end of the needle, thereby minimizing the possibility of clogging the needle.
    • 在本发明的一个方面中,提供了一种药物输送装置,其包括用于容纳药物的储存器并且具有近端和远端,所述药物包括液体载体中的固体悬浮液。 此外,药物输送装置包括与储液器流体连通并具有用于注射到患者体内的远端和储液器内的近端的针。 累积表面至少部分围绕针的近端限定在针的近端。 积聚表面限定了向远侧延伸的凹陷,其尺寸和形状被设计成在使用期间收集从悬浮液中出来的固体。 有利的是,就本发明而言,积聚表面允许固体积聚在与针的近端间隔开的位置处,由此使得堵塞针的可能性最小化。