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1. 发明授权

EP0366480B1 Method and compositions for treating Alzheimer's disease, related dementias & epilepsy 失效
标题翻译：方法和用于治疗阿尔茨海默氏病，痴呆有关的癫痫和手段。
公开(公告)号：EP0366480B1
公开(公告)日：1994-08-24
申请号：EP89311089.0
申请日：1989-10-27
申请人： BAR ILAN UNIVERSITY
发明人： Yehuda, Shlomo
IPC分类号： A61K31/20
CPC分类号： A61K31/23 , A23L33/12 , A61K31/20

2. 发明授权

EP0275643B1 Physiologically active and nutritional composition 有权
标题翻译：生理活性和营养成分
公开(公告)号：EP0275643B1
公开(公告)日：1991-04-17
申请号：EP87310416.0
申请日：1987-11-25
申请人： BAR ILAN UNIVERSITY
发明人： Yehuda, Shlomo
IPC分类号： A61K31/20 , A61K31/23 , A23L1/03
CPC分类号： A61K31/23 , A23L33/12 , A61K31/20

3. 发明公开

EP0366480A2 Method and compositions for treating Alzheimer's disease, related dementias & epilepsy 失效
标题翻译：方法和用于治疗阿尔茨海默氏病，痴呆有关的癫痫和手段。
公开(公告)号：EP0366480A2
公开(公告)日：1990-05-02
申请号：EP89311089.0
申请日：1989-10-27
申请人： BAR ILAN UNIVERSITY
发明人： Yehuda, Shlomo
IPC分类号： A61K31/20
CPC分类号： A61K31/23 , A23L33/12 , A61K31/20
摘要： Alzheimer's disease, related dementias and epilepsy are treated by administering in absence of an oily carrier or diluent which comprises at least one member of the group consisting of C₈₋₁₈ saturated fatty acids, oleic acid and derivatives of these acids, to a person having the symptoms thereof, or to a person susceptible to epilepsy, a symptom-alleviating amount of a composition of matter which comprises (a) from about 13.0 to about 27.5% by weight of linolenic acid and/or derivatives thereof, and (b) about 87.0 to about 72.5% by weight of at least one compound selected from the group consisting of linoleic acid and/or derivatives thereof, the derivatives of linolenic and linoleic acid being calculated as the free acids, and being both physiologically hydrolyzable and pharmacologically acceptable, or of a pharmaceutical formulation or nutritional composition containing ingredients (a) and (b) in the recited proportions.
摘要翻译：阿尔茨海默氏病，痴呆有关的癫痫和通过在不存在，它包括所述组包括C8-18饱和脂肪酸，油酸和酸合成的衍生物中的至少一个成员的油性载体或稀释剂的治疗管理，给具有人其症状，或易患癫痫的人，无论哪个重量亚麻酸和/或其衍生物的方法包括：（a）约13.0至约27.5％的组合物的症状减轻的量，和（b）约87.0 重量的至少一种化合物的选自亚油酸和/或它们的衍生物中选择的约72.5％，亚麻酸和亚油酸的衍生物被计算为游离酸，并且是这两种生理上可水解的和药理学上可接受的，或药物制剂或营养组合物含有成分（A）和（b）中所叙述的比例。

4. 发明公开

EP0366480A3 Method and compositions for treating Alzheimer's disease, related dementias & epilepsy 失效
标题翻译：治疗阿尔茨海默病的方法和组合，相关的治疗和疗效
公开(公告)号：EP0366480A3
公开(公告)日：1991-02-06
申请号：EP89311089.0
申请日：1989-10-27
申请人： BAR ILAN UNIVERSITY
发明人： Yehuda, Shlomo
IPC分类号： A61K31/20
CPC分类号： A61K31/23 , A23L33/12 , A61K31/20
摘要： Alzheimer's disease, related dementias and epilepsy are treated by administering in absence of an oily carrier or diluent which comprises at least one member of the group consisting of C₈₋₁₈ saturated fatty acids, oleic acid and derivatives of these acids, to a person having the symptoms thereof, or to a person susceptible to epilepsy, a symptom-alleviating amount of a composition of matter which comprises (a) from about 13.0 to about 27.5% by weight of linolenic acid and/or derivatives thereof, and (b) about 87.0 to about 72.5% by weight of at least one compound selected from the group consisting of linoleic acid and/or derivatives thereof, the derivatives of linolenic and linoleic acid being calculated as the free acids, and being both physiologically hydrolyzable and pharmacologically acceptable, or of a pharmaceutical formulation or nutritional composition containing ingredients (a) and (b) in the recited proportions.

5. 发明公开

EP0275643A1 Physiologically active and nutritional composition 有权
标题翻译： Physiologisch wirksame和nährendeZusammensetzung。
公开(公告)号：EP0275643A1
公开(公告)日：1988-07-27
申请号：EP87310416.0
申请日：1987-11-25
申请人： BAR ILAN UNIVERSITY
发明人： Yehuda, Shlomo
IPC分类号： A61K31/20 , A61K31/23 , A23L1/03
CPC分类号： A61K31/23 , A23L33/12 , A61K31/20
摘要： A composition useful in a method for treating a mammal in order to induce memory enhancement, analgesia, sleep regulation and (or) inhibition of the symtoms of senility, comprises from about 13.0 to about 27.5% by weight of linolenic acid, balance linoleic acid. Physiologically hydrolyzable and pharmacologically acceptable derivatives of these acids may also be used. The specified combination of acids may be administered as pharmaceutical formulations or nutritional compositions.
摘要翻译：用于治疗哺乳动物以便诱导记忆增强，镇痛，睡眠调节和（或）衰老症状的（或）抑制的方法中的组合物包含约13.0至约27.5重量％的亚麻酸，平衡亚油酸。也可以使用这些酸的生理上可水解和药理学上可接受的衍生物。指定的酸组合可以作为药物制剂或营养组合物施用。

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