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    • 4. 发明公开
    • VASODILATOR FORMULATION AND METHOD OF USE
    • VASODILATOR配方和使用方法
    • EP3065730A1
    • 2016-09-14
    • EP14856949.4
    • 2014-11-04
    • Atp Institute Pty Ltd.
    • LEGGE, Matthew
    • A61K31/198A61K36/534A61K36/67A61P9/08
    • A topically admimstrable vasodilator formulation comprises arginine and/or one or more derivatives thereof, black pepper extract and/or one or more components or derivatives thereof; and peppermint extract and/or one or more components or derivatives thereof. The formulation may further comprise rosemary oil, a penetration enhancers, an ecdysteroid and/or one or more other agents that enhance the vasodilator activity of the formulation. The valodilator formulation may be suitable for treating or preventing a disease, disorder or condition associated with a decrease and/or impairment of blood flow in a subject by topically administration to the subject.
    • 局部可吸入的血管舒张剂制剂包含精氨酸和/或其一种或多种衍生物,黑胡椒提取物和/或其一种或多种组分或衍生物; 和薄荷提取物和/或其一种或多种组分或其衍生物。 该制剂还可以包含迷迭香油,渗透增强剂,蜕皮甾类和/或一种或多种增强制剂的血管扩张剂活性的其它药剂。 通过局部施用给受试者,所述二甲洛英制剂可适用于治疗或预防与受试者血流减少和/或损伤相关的疾病,病症或病症。