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1. 发明公开

EP1706021A1 METHOD FOR DETECTING ARTIFACTS IN DATA 审中-公开
标题翻译：方法用于检测数据失真的
公开(公告)号：EP1706021A1
公开(公告)日：2006-10-04
申请号：EP04813356.5
申请日：2004-12-08
申请人： ABBOTT LABORATORIES
发明人： LOWERY, Michael, G. , SHAIN, Eric, B. , KHALIL, Omar, S.
IPC分类号： A61B5/00 , G01N21/35 , G01N33/487
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14535 , A61B5/7207 , G01N21/49
摘要： A method for identifying artifacts occurring during a measurement of the concentration of an analyte in a biological sample by means of an apparatus that employs optical probes, introduces electromagnetic radiation into tissue, and collects and detects radiation emitted at a distance from the point at which the electromagnetic radiation is introduced. The values of intensity of radiation emitted are collected and used in the method to generate a relationship between these values and the concentration of an analyte in the tissue or the disease state of a patient. The method involves the use of an algorithm that identifies artifacts in the data resulting from motion of the patient and allows the rejection oA method for identifying artifacts occuring during a measurement of the concentration of an analyte in a biological sample by means of an apparatus that employs temperature-controlled optical probes, introduces electromagnetic radiation into tissue, and collects and detects radiation emitted at a distance from the point at which the electromagnetic radiation is introduced. The values of intensity of radiation emitted at different wavelenghts, at different distances between the lht introduction site (s) and the light collection site (s), and at different temperatures are collected and used in the method to generate a relationship between these values and the concentration of an analyte in the tissue or the disease state of a patient. The method involves the use of an algorithm that identifies artifacts in the data resulting from motion of the patient and allows the rejection of data sets that contain these artifacts. The algorithm identifies sudden changes in the magnitude and direction in a sequence of collected signals.

2. 发明公开

EP1326533A2 DEVICE AND METHOD FOR OBTAINING INTERSTITIAL FLUID FROM A PATIENT FOR DIAGNOSTIC TESTS 有权
标题翻译：装置脱除组织间液对病人进行诊断测试
公开(公告)号：EP1326533A2
公开(公告)日：2003-07-16
申请号：EP01979778.6
申请日：2001-10-11
申请人： Abbott Laboratories
发明人： HENNING, Timothy, P. , LOWERY, Michael, G.
IPC分类号： A61B5/15
CPC分类号： A61B5/14514 , A61B5/150022 , A61B5/150061 , A61B5/150099 , A61B5/150389 , A61B5/150442 , A61B5/150503 , A61B5/150946 , A61B5/150969 , A61B5/15142 , A61B2010/008
摘要： A device for obtaining a sample of interstitial fluid from a patient for use in monitoring the level of blood glucose in the patient. The device comprises a hollow tube having a wall surrounding a cavity, wherein the wall of the tube contains a multiplicity of pores. The hollow tube is inserted into the tissues through the skin with the help of anintroduction needle. No external suction is applied.

3. 发明授权

EP1326533B1 DEVICE FOR OBTAINING INTERSTITIAL FLUID FROM A PATIENT FOR DIAGNOSTIC TESTS 有权
标题翻译：装置脱除组织间液对病人进行诊断测试
公开(公告)号：EP1326533B1
公开(公告)日：2005-12-28
申请号：EP01979778.6
申请日：2001-10-11
申请人： ABBOTT LABORATORIES
发明人： HENNING, Timothy, P. , LOWERY, Michael, G.
IPC分类号： A61B5/15
CPC分类号： A61B5/14514 , A61B5/150022 , A61B5/150061 , A61B5/150099 , A61B5/150389 , A61B5/150442 , A61B5/150503 , A61B5/150946 , A61B5/150969 , A61B5/15142 , A61B2010/008
摘要： A device for obtaining a sample of interstitial fluid from a patient for use in monitoring the level of blood glucose in the patient. The device comprises a hollow tube having a wall surrounding a cavity, wherein the wall of the tube contains a multiplicity of pores.

4. 发明公开

EP0946122A2 METHOD AND APPARATUS FOR OBTAINING BLOOD FOR DIAGNOSTIC TESTS 失效
标题翻译： DEVICE采血诊断检测
公开(公告)号：EP0946122A2
公开(公告)日：1999-10-06
申请号：EP97954551.0
申请日：1997-12-04
申请人： Abbott Laboratories
发明人： CUNNINGHAM, David, D. , HENNING, Timothy, P. , SHAIN, Eric, B. , YOUNG, Douglas, F. , LOWERY, Michael, G. , SCHAPIRA, Thomas, G. , GRAHAM, Hugh, W. , MUETTERTIES, Andrew, J. , CHAMBERS, Geoffrey, R. , HUGHES, Graham, J. , WATKIN, Jared, L. , PROKOP, Gary, F. , GOLDFARB, Joshua, P.
IPC分类号： A61B5 , G01N33
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150099 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150664 , A61B5/15113 , A61B5/15125 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B5/411 , A61B2562/0295
摘要： Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: (a) forming an unobstructed opening in the area of the skin from which the sample of blood is to be extracted; and (b) extracting the sample of blood from the unobstructed opening in the skin, with the aid of a vacuum and a stretching of the skin. In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises: (a) a device for forming an unobstructed opening in an area of skin from which said sample is to be extracted, preferably a lancing assembly; and (b) a vacuum pump. Preferably, the apparatus also includes a housing. In a further aspect of the invention, a pneumatic lancing assembly is provided. The pneumatic lancing assembly uses differential gas pressure to thrust a lancet into skin tissue. In another aspect of this invention, an article is provided for an article capable of both collecting blood and detecting an analyte in that blood. The article, which contains an appropriate detection element for determining the amount of analyte in the blood, can be used in conjunction with a meter that measures the signal generated by the detection element of the article.

5. 发明公开

EP0783694A1 DEVICES AND METHODS UTILIZING ARRAYS OF STRUCTURES FOR ANALYTE CAPTURE 失效
标题翻译：设备及其使用方法结构领域的ANALYTFANG的
公开(公告)号：EP0783694A1
公开(公告)日：1997-07-16
申请号：EP95936210.0
申请日：1995-09-29
申请人： Abbott Laboratories
发明人： HANSMANN, Douglas, D. , GRACE, John, P. , LOWERY, Michael, G. , OOSTA, Gary, M. , LOOMIS, Neil, W. , SHAIN, Eric, B. , SCHAPIRA, Thomas, G.
IPC分类号： G01N33 , B01L3 , C08G18 , C12Q1 , G01N37
CPC分类号： G01N33/5304 , B01L3/502746 , B01L3/502753 , B01L2200/10 , B01L2300/0636 , B01L2300/0825 , B01L2400/0406 , B01L2400/086 , C08G18/0866 , C08G18/10 , G01N33/54366 , G01N33/54393 , Y10S435/81 , Y10S436/804 , Y10S436/805 , Y10S436/809 , Y10S436/81
摘要： The present invention relates to analytical devices for determining the presence or amount of an analyte in a test sample. The analytical devices comprise an inlet port, a vent, a channel, and an array of structures. The structures have immobilized reagent covalently or non-covalently attached to the surface of the structures. The immobilized reagent captures analyte in the test sample where it is detected by a detection system. The present invention also provides methods and reagents for performing assays utilizing the analytical devices of the present invention. The present invention also provides methods of manufacturing the analytical devices of the present invention.

6. 发明授权

EP0783694B1 DEVICES AND METHODS UTILIZING ARRAYS OF STRUCTURES FOR ANALYTE CAPTURE 失效
标题翻译：设备和方法，结构FIELDS绑定使用分析物
公开(公告)号：EP0783694B1
公开(公告)日：2003-11-12
申请号：EP95936210.4
申请日：1995-09-29
申请人： Abbott Laboratories
发明人： HANSMANN, Douglas, D. , GRACE, John, P. , LOWERY, Michael, G. , OOSTA, Gary, M. , LOOMIS, Neil, W. , SHAIN, Eric, B. , SCHAPIRA, Thomas, G.
IPC分类号： G01N33/543 , B01L3/00 , G01N33/53
CPC分类号： G01N33/5304 , B01L3/502746 , B01L3/502753 , B01L2200/10 , B01L2300/0636 , B01L2300/0825 , B01L2400/0406 , B01L2400/086 , C08G18/0866 , C08G18/10 , G01N33/54366 , G01N33/54393 , Y10S435/81 , Y10S436/804 , Y10S436/805 , Y10S436/809 , Y10S436/81

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