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    • 1. 发明公开
    • Biodegradable film dressing and method for its formation
    • Biologisch abbaubarer Wundferband in Form einesSprühfilmsund Verfahren zu seiner Herstellung。
    • EP0560014A1
    • 1993-09-15
    • EP93100358.6
    • 1993-01-13
    • ATRIX LABORATORIES, INC.
    • Tipton, Arthur J.Fujita, Shawn M.Dunn, Richard L.
    • A61L25/00
    • A61L15/44A61K9/7015A61L24/0042A61L26/00A61L26/0066A61L26/0076A61L26/0085A61L26/009A61L2300/252A61L2300/604
    • The invention is directed to a biodegradable film dressing with or without additional therapeutic agents, an apparatus for spray delivery and a method for formation of the film dressing on a human or animal tissue. The film dressing is formed from a liquid composition of at least one biodegradable/bioerodible thermoplastic polymer in a pharmaceutically acceptable solvent. The spray apparatus includes a vessel containing the liquid composition with a dispensing means. The film is formed by dispensing, preferably by spraying, the liquid composition onto a tissue site and contacting the liquid composition with an aqueous based fluid to coagulate or solidify the film onto the human or animal tissue. The biodegradable film can be used to protect and to promote healing of injured tissue and/or to deliver biologically active agents.
    • 本发明涉及具有或不具有其他治疗剂的生物降解性膜敷料,用于喷雾递送的装置和在人或动物组织上形成膜敷料的方法。 薄膜敷料由药学上可接受的溶剂中的至少一种生物可降解/生物可侵蚀的热塑性聚合物的液体组合物形成。 喷雾装置包括容纳具有分配装置的液体组合物的容器。 通过优选通过将液体组合物分配到组织部位上并且使液体组合物与基于水的液体接触使凝胶或固化到人体或动物组织上而形成膜。 可生物降解的膜可用于保护和促进损伤组织的愈合和/或递送生物活性剂。