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1. 发明公开

EP2950858A1 DOSING INJECTOR 审中-公开
标题翻译：配量注射器
公开(公告)号：EP2950858A1
公开(公告)日：2015-12-09
申请号：EP14703749.3
申请日：2014-01-29
申请人： ALLERGAN, INC.
发明人： FRANKLIN, Ethan
IPC分类号： A61M5/315
CPC分类号： A61M5/31526 , A61M5/31581 , A61M5/31595 , A61M2005/31508
摘要： A metered dose syringe includes a barrel having an open end and a opposing spaced apart port adapted to receive a needle. A plunger rod is provided and slidably disposed within the barrel through the barrel open end. Structure interconnected with the barrel and the plunger rod is provided for enabling stepwise movement of the plunger rod within the barrel. A syringe within the scope of our present invention permits injection of repeated and accurate doses due to the physical stops or dosage administered indicators.
摘要翻译：定量剂量注射器包括具有开口端和适于接收针的相对的间隔开端口的针筒。柱塞杆设置并且可滑动地设置在筒内通过筒开口端。提供与筒和柱塞杆相互连接的结构，用于使柱塞杆能够在筒内逐步移动。在我们的本发明范围内的注射器由于物理停止或剂量给予指示剂而允许注射重复的和精确的剂量。

2. 发明公开

EP2685945A2 SELF-ADJUSTING GASTRIC BAND 审中-公开
标题翻译：自我调节胃带
公开(公告)号：EP2685945A2
公开(公告)日：2014-01-22
申请号：EP12713446.8
申请日：2012-03-14
申请人： Allergan, Inc.
发明人： SNOW, Sean , BABKES, Mitchell H. , BORRELL, Marcos , DEUEL, Christopher R. , DOMINGUEZ, Zachary P. , FRANKLIN, Ethan , HONARYAR, Babak , TORJESEN, Erik
IPC分类号： A61F5/00 , A61B5/00
CPC分类号： A61F5/0056
摘要： Generally described herein are automatic, self-adjusting, gastric banding systems and improvements thereof, that are capable of automatically relaxing and contracting in response to a large bolus passing through the area of a patient's stomach constricted by a gastric band. Alternatively, and/or in addition in one or more embodiments, the gastric banding systems described herein may also help prevent pouch dilatation and/or erosion. The apparatus and systems described herein aid in facilitating obesity control and/or treating obesity-related diseases while generally being non-invasive once implanted. Furthermore, certain embodiments of the self-adjusting gastric banding systems disclosed herein are automatically adjustable without complicated fluid control mechanisms, flow rate limiting devices, and/or valves. The automatic adjustments may also be made in response to other changes in the patient's esophageal-gastric junction, for example, in response to size, shape, and or location changes.
摘要翻译：一般在此描述的是自动的，自我调节的胃束带系统及其改进，其能够响应于大丸通过胃带收缩的患者胃部区域而自动放松和收缩。可替代地和/或另外在一个或多个实施例中，本文所述的胃束带系统还可以帮助防止囊扩张和/或侵蚀。本文所述的装置和系统有助于促进肥胖控制和/或治疗肥胖相关疾病，而一旦植入则通常是非侵入性的。此外，本文公开的自调节胃束带系统的某些实施例可自动调节而无需复杂的流体控制机构，流量限制装置和/或阀。例如，响应于患者的食管 - 胃连接处的其他变化，响应于尺寸，形状和/或位置变化，也可以进行自动调整。

3. 发明公开

EP2162102A1 HYDRAULIC GASTRIC BAND WITH COLLAPSIBLE RESERVOIR 有权
标题翻译：液压LAP-BAND带可折叠水库
公开(公告)号：EP2162102A1
公开(公告)日：2010-03-17
申请号：EP08769577.1
申请日：2008-05-22
申请人： ALLERGAN, INC.
发明人： BIRK, Janel , FRANKLIN, Ethan
IPC分类号： A61F5/00
CPC分类号： A61F5/0003 , A61B5/0031 , A61B5/036 , A61B5/411 , A61B17/1355 , A61B2562/0247 , A61B2562/043 , A61F5/0053 , G06F19/00
摘要： A self-regulating gastric band apparatus for adjusting stoma size. The apparatus includes an adjustable gastric band that has an inner ring expanding with injected fluid. A band adjustment assembly is provided for implanting with the gastric band that includes a sensor for sensing fluid pressure in the inner ring. The band adjustment assembly further includes a pump assembly connected to the expandable inner ring and to a controller that can operate the pump assembly to adjust the volume of the fluid in the band based on the sensed fluid pressure. The band adjustment assembly includes memory storing an operating range relative to a target fluid pressure, and the pump assembly is operated to maintain the sensed band pressure within the operating range. The target pressure being set to maintain pressure variations below a predefined variation limit generally corresponding with satiated fill volumes for a particular patient and implanted band. An elongated fluid reservoir may extend along a substantial part of a fill tube. A balloon-like expandable fluid reservoir in fluid communication with the pump assembly may store a volume of the fluid for adjusting the volume of fluid in the lumen. A protective outer sheath may be provided around the exterior of an expandable fluid reservoir in both a first, deflated state, and a second, inflated state of the reservoir.

4. 发明公开

EP2720652A1 OVER MOLDED IMPLANTABLE DEVICE TO PROTECT TUBING FROM PUNCTURE 审中-公开
标题翻译： IMPLANTIERBAREÜBERSPRITZTEVORRICHTUNGFÜRDEN SCHUTZ EINES TUBUS VOR PERFORATION
公开(公告)号：EP2720652A1
公开(公告)日：2014-04-23
申请号：EP12733547.9
申请日：2012-06-12
申请人： Allergan, Inc.
发明人： FRANKLIN, Ethan , SCHWAB, Justin, J.
IPC分类号： A61F5/00 , A61M39/02 , F16L11/18
CPC分类号： A61F5/0056 , A61M39/0208 , A61M2039/0226 , F16L35/00
摘要： An implantate device used in a gastric band system includes an access port (200), a tube (202) coupled to the access port, and a shielding device (300) covering a portion of the tube. The shielding device is positioned adjacent to the access port and covers the end of the tube coupled to the access port. The shielding device is made from a puncture resistant material, to protect the tube from puncture by a misplaced syringe needle inserted by a physician.
摘要翻译：在胃束带系统中使用的植入装置包括进入口（200），耦合到进入口的管（202）和覆盖管的一部分的屏蔽装置（300）。屏蔽装置定位成与接近端口相邻并且覆盖耦合到接入端口的管的端部。屏蔽装置由防刺穿材料制成，以通过被医生插入的错位注射器针来保护管免于刺穿。

5. 发明公开

EP3122332A1 DISSOLVABLE MICRONEEDLES FOR SKIN TREATMENT 有权
标题翻译： LÖSLICHEMIKRONADELN ZUR HAUTBEHANDLUNG
公开(公告)号：EP3122332A1
公开(公告)日：2017-02-01
申请号：EP15716319.7
申请日：2015-03-27
申请人： ALLERGAN, INC.
发明人： SCHWAB, Justin J. , AUGARTEN, Michael , DOMINGUEZ, Zachary , FRANKLIN, Ethan , KAYDA, Edwin J. , METZNER, Jason
IPC分类号： A61K9/00 , A61K47/36 , A61K9/70 , A61M37/00 , A61M5/142
摘要： A skin treatment device is provided including bioerodible polymeric microneedles which are designed to more effectively deliver beneficial agents to the skin. The device includes a flexible substrate and an arrangement, for example, an array, of microneedles projecting from the substrate.
摘要翻译：提供了一种皮肤治疗装置，包括可生物降解的聚合物微针，其被设计成更有效地将有益剂递送至皮肤。该装置包括柔性基板和从基板突出的微针阵列，例如阵列。

6. 发明公开

EP2685943A2 SELF-ADJUSTING GASTRIC BAND 有权
标题翻译： SELF-LAP-BAND
公开(公告)号：EP2685943A2
公开(公告)日：2014-01-22
申请号：EP12711728.1
申请日：2012-03-14
申请人： Allergan, Inc.
发明人： FRANKLIN, Ethan , SNOW, Sean , TORJESEN, Erik , SCHWAB, Justin J. , DOMINGUEZ, Zachary P.
IPC分类号： A61F5/00 , A61B5/00
CPC分类号： A61F5/0056
摘要： Generally described herein are automatic, self-adjusting, gastric banding systems and improvements thereof, that are capable of automatically relaxing and contracting in response to a large bolus passing through the area of a patient's stomach constricted by a gastric band. Alternatively, and/or in addition in one or more embodiments, the gastric banding systems described herein may also help prevent pouch dilatation and/or erosion. The apparatus and systems described herein aid in facilitating obesity control and/or treating obesity-related diseases while generally being non-invasive once implanted. Furthermore, certain embodiments of the self-adjusting gastric banding systems disclosed herein are automatically adjustable without complicated fluid control mechanisms, flow rate limiting devices, and/or valves. The automatic adjustments may also be made in response to other changes in the patient's esophageal-gastric junction, for example, in response to size, shape, and or location changes.

7. 发明公开

EP2471573A3 Implantable access port device and attachment system 有权
标题翻译：植入式接入端口设备和附件系统
公开(公告)号：EP2471573A3
公开(公告)日：2012-10-31
申请号：EP12161754.2
申请日：2009-04-17
申请人： Allergan, Inc.
发明人： FRANKLIN, Ethan , BIRK, Janel A
IPC分类号： A61M39/02
CPC分类号： A61M39/0208 , A61B17/064 , A61B17/068 , A61F5/0056 , A61F5/0089 , A61M2039/0223
摘要： A system for attaching an access port to bodily tissue includes an access port assembly and including an access port having a generally central axis (52). The access port assembly further includes an attachment mechanism structured to enable the access port to be attached, for example, to an abdominal muscle of a patient. The system includes a rotating activator (62) having first and second protrusions (112) receiving an anchor (70) therebetween for reversibly deploying the anchor in a camming manner.
摘要翻译：用于将进入端口附接到身体组织的系统包括进入端口组件并且包括具有大致中心轴线（52）的进入端口。进入端口组件还包括附接机构，该附接机构构造成使得进入端口能够附接到例如患者的腹部肌肉。该系统包括具有第一和第二突起（112）的旋转激励器（62），所述第一和第二突起（112）在其间接收锚（70）以用于以凸轮方式可逆地展开锚。

8. 发明公开

EP2471573A2 Implantable access port device and attachment system 有权
标题翻译： Implantierbare Zugangsportvorrichtung und Befestigungssystem
公开(公告)号：EP2471573A2
公开(公告)日：2012-07-04
申请号：EP12161754.2
申请日：2009-04-17
申请人： Allergan, Inc.
发明人： FRANKLIN, Ethan , BIRK, Janel A
IPC分类号： A61M39/02
CPC分类号： A61M39/0208 , A61B17/064 , A61B17/068 , A61F5/0056 , A61F5/0089 , A61M2039/0223
摘要： A system for attaching an access port to bodily tissue includes an access port assembly and including an access port having a generally central axis (52). The access port assembly further includes an attachment mechanism structured to enable the access port to be attached, for example, to an abdominal muscle of a patient. The system includes a rotating activator (62) having first and second protrusions (112) receiving an anchor (70) therebetween for reversibly deploying the anchor in a camming manner.
摘要翻译：用于将进入端口附接到身体组织的系统包括进入口组件，并且包括具有大致中心轴线（52）的进入口。进入端口组件还包括附接机构，其被构造成使得接入端口能够例如连接到患者的腹部肌肉。该系统包括具有第一和第二突出物（112）的旋转活化器（62），该第一和第二突起部分（112）在其间容纳锚固件（70），用于以凸轮的方式可逆地展开锚固件。

9. 发明授权

EP3122332B1 DISSOLVABLE MICRONEEDLES FOR SKIN TREATMENT 有权
公开(公告)号：EP3122332B1
公开(公告)日：2020-05-27
申请号：EP15716319.7
申请日：2015-03-27
申请人： ALLERGAN, INC.
发明人： SCHWAB, Justin J. , AUGARTEN, Michael , DOMINGUEZ, Zachary , FRANKLIN, Ethan , KAYDA, Edwin J. , METZNER, Jason
IPC分类号： A61K9/00 , A61K47/36 , A61K9/70 , A61M37/00 , A61M5/142

10. 发明公开

EP2471572A3 Implantable access port device 审中-公开
标题翻译：一种可植入的注射端口器件
公开(公告)号：EP2471572A3
公开(公告)日：2012-10-17
申请号：EP12161753.4
申请日：2009-04-17
申请人： Allergan, Inc.
发明人： FRANKLIN, Ethan , BIRK, Janel, A.
IPC分类号： A61M39/02
CPC分类号： A61M39/0208 , A61B17/064 , A61B17/068 , A61F5/0056 , A61F5/0089 , A61M2039/0223
摘要： An access port having a generally central axis (52). The access port assembly further includes an attachment mechanism structured to enable the access port to be attached, for example, to an abdominal muscle of a patient. The port comprises a chamber (37) and an inlet/outlet connector (38) in communication with the camber. The inlet/outlet connector includes a strain relief element (50).

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