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    • 4. 发明公开
    • High speed modem suitable for operating with a switched network
    • Zum Arbeiten mit einemWählnetzgeeignetes Hochgeschwindigkeits-Modem。
    • EP0008521A2
    • 1980-03-05
    • EP79301664.3
    • 1979-08-15
    • University of Illinois Foundation
    • Keasler, William E.Bitzer, Donald L.Tucker, Paul T.
    • H04L5/02H04L27/00
    • H04L27/2602H04L27/2627H04L27/2649H04L27/2657H04L27/3836
    • A high speed modem suitable for operating with a switched network and capable of achieving essentially 9600 bit per second information transfer rate through the switched telephone network. The high bit rate is achieved notwithstanding the variations in the characteristics of the switched telephone network by phase and amplitude modulating a plurality of sub-carriers (39) at a relatively low baud rate. Correlation detection (35) is employed at the receiver (33-38) to extract or demodulate the information contained in the various sub-carriers. To allow correlation detection with orthogonal signals, each of the sub-carriers is harmonically related to a fundamental which fundamental is, however, slightly higher than the baud rate. This allows the receiver (33-38) to delay correlation for a "gap" time, which reduces the effect of transients produced by modulation and also provides greater tolerance to inter-symbol distortion. Since the fundamental of all the sub-carriers is higher than the baud rate, the receiver "sees" orthogonal signals during the integration or correlation time which is maintained as the period of the fundamental. In addition to the information sub-carriers, a pair of unmodulated sub-carriers (36) are also transmitted to enable the receiver to maintain the correlation interval in proper synchronization with the transmitter, and to correct for phase distortion and frequency offset.
    • 适用于交换网络的高速调制解调器,能够通过交换电话网实现基本上9600比特的信息传输速率。 尽管通过以相对低的波特率对多个子载波(39)进行相位和幅度调制,交换电话网络的特性的变化也实现了高比特率。 在接收机(33-38)采用相关检测(35)来提取或解调包含在各种子载波中的信息。 为了允许与正交信号的相关检测,每个子载波与基波谐波相关,然而基波稍微高于波特率。 这允许接收机(33-38)延迟“间隙”时间的相关性,这降低了由调制产生的瞬变的影响,并且还提供对符号间失真的更大的容限。 由于所有子载波的基波都高于波特率,因此接收机在整合或相关时间期间“看到”正交信号,其被保持为基波周期。 除了信息子载波之外,还发送一对未调制的子载波(36),以使接收机能够将相关间隔保持与发射机的适当同步,并且校正相位失真和频率偏移。
    • 6. 发明公开
    • ANAPLASMA ANTIGEN
    • ANAPLASMA抗原
    • EP0081575A1
    • 1983-06-22
    • EP82902304.0
    • 1982-06-17
    • UNIVERSITY OF ILLINOIS FOUNDATION
    • RISTIC, MiodragLEVY, Michael G.
    • A61K39
    • A61K39/0233Y02A50/403
    • Water soluble antigens specific for Anaplasma sp. are produced and isolated in vitro. For example, a non-living, stable, soluble Anaplasma marginale antigen (designated "Anablock") is characterized, interalia, as a glycoprotein having a molecular weight of about 53,000 and an isoelectric point of about 6. Vaccine compositions providing immunologically effective quantities of soluble specific antigen and a suitable adjuvant are capable of provoking protective immune response to challenge with virulent Anaplasma, e.g., blocking the development of virulent A. marginale infection. The protective immune response in vaccinates is serologically characterized by positive results in latex agglutination (LAT) and fluorescent antibody (IFA) test, but negative results in complement fixation (CF) and capillary tube agglutination (CA) test.
    • 抗原可溶于水,对无形体无特异性。 在体外生产和分离。 例如,稳定的非生命可溶性边缘无形体抗原(称为“Anablock”)特征在于其特别是具有约53,000的分子量和约6的等电点的糖蛋白。 含有免疫有效量的可溶性特异性抗原和合适佐剂的疫苗可以引发针对有毒无形体的保护性免疫应答,例如通过阻断由A引起的感染的发展。 剧毒边际。 接种受试者中的保护性免疫应答的血清学特征为乳胶凝集试验(LAT)和荧光抗体(ISA)中的阳性结果,但是通过补体结合试验(CS)中的阴性结果, 并在毛细管(CA)中凝集。