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    • 3. 发明公开
    • COMPOSITION FOR PREVENTING ADHESION
    • ZUSAMMENSETZUNG ZUR PRENVENTION VONADHÄSION
    • EP2371371A2
    • 2011-10-05
    • EP09830544.4
    • 2009-11-25
    • Shin Poong Pharmaceutical Co. Ltd.Postech Academy-industry Foundation
    • CHO, Il HwanHAHN, Sei KwangHWANG, Eui JinSHIN, Jang SikYEOM, Junseok
    • A61K31/728A61K31/722A61P41/00
    • A61K31/722A61K31/728
    • The present invention relates to a composition for preventing tissue adhesion which comprising a bio-compatible hyaluronic acid and a polymer compound. More specifically, the invention is a composition containing hyaluronic acid which has not been modified by a chemical crosslinking or other chemical modification a method for preparing the same, and a composition for adhesion prevention with superior efficacy..
      The composition of the present invention for preventing adhesion exhibits a physical barrier function and a new adhesion prevention function whereby thrombus formation, which is the basis of adhesion, is inhibited. Unlike conventional compositions which simply mixpolymeric substances that function as physical barriers, the present invention performs a more effective role as a physical barrier by undergoing decomposition, absorption and excretion after a certain period inside a human body, does not interfere with healing of scars following surgery, and exhibits superior effects since application to areas of surgery is convenient.
    • 本发明涉及一种用于预防组织粘连的组合物,其包含生物相容性透明质酸和高分子化合物。 更具体地说,本发明是含有透明质酸的组合物,其通过化学交联或其它化学改性未被改性,其制备方法,以及具有优异功效的防粘结组合物。本发明的预防组合物 粘附表现出物理屏障功能和新的粘附防止功能,其中作为粘附基础的血栓形成被抑制。 不同于简单地混合作为物理屏障的混合物质的常规组合物,本发明通过在人体内经过一定时间后经历分解,吸收和排泄而作为物理屏障起到更有效的作用,不影响手术后瘢痕愈合 ,并且表现出优异的效果,因为应用于手术领域是方便的。