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1. 发明公开

EP1467661A4 SEPTAL OCCLUDER AND ASSOCIATED METHODS 审中-公开
标题翻译： SEPTUMVERSCHLUSSEINRICHTUNG UNDZUGEHÖRIGEVERFAHREN
公开(公告)号：EP1467661A4
公开(公告)日：2008-11-05
申请号：EP02795975
申请日：2002-12-19
申请人： NMT MEDICAL INC
发明人： RYAN CAROL A , CHANDUSZKO ANDRZEJ J
IPC分类号： A61B17/00 , A61B17/04 , A61B17/08 , A61D1/00 , A61M20060101 , H04W84/14
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/0475 , H04M1/68 , H04M1/723 , H04M1/72505 , H04W84/14
摘要： Devices are provided for closing septal defects such as PFOs. The devices generally include a proximal anchor member (52), a distal anchor member (54), and a flexible center joint (56) connecting the two anchor members.
摘要翻译：提供器件用于封闭诸如PFO的间隔缺陷。该装置通常包括近端锚定构件52，远端锚定构件54和连接两个锚定构件的柔性中心接头56。

2. 发明公开

EP1962695A1 CATCH MEMBERS FOR OCCLUDER DEVICES 审中-公开
标题翻译：钓鱼链接，闭合装置
公开(公告)号：EP1962695A1
公开(公告)日：2008-09-03
申请号：EP06846765.3
申请日：2006-12-21
申请人： NMT Medical, Inc.
发明人： OPOLSKI, Steven, W. , FORDE, Sean, T. , KLADAKIS, Stephanie, M. , CALLAGHAN, David, J.
IPC分类号： A61B17/00
CPC分类号： A61B17/1215 , A61B17/0057 , A61B2017/00004 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： Devices and techniques for modifying and maintaining a configuration of an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices and techniques relate particularly to, but are not limited to, modifying and maintaining a configuration of a PFO occluder made from a polymer tube. The proximal end of a catch member may be provided with one or more protrusions, or arms, or bump or other element for securing the occluder in a partial or fully deployed configuration, either temporarily or permanently.

3. 发明公开

EP1509144A4 DEVICE WITH BIOLOGICAL TISSUE SCAFFOLD FOR INTRACARDIAC DEFECT CLOSURE 审中-公开
标题翻译：与生物组织框架心内缺损封堵设备
公开(公告)号：EP1509144A4
公开(公告)日：2008-09-03
申请号：EP03756366
申请日：2003-06-03
申请人： NMT MEDICAL INC
发明人： RYAN CAROL A , CARR ROBERT M JR
IPC分类号： A61B17/00 , A61B17/08 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/1205 , A61F2310/00365
摘要： The invention provides an intracardiac occluder (10), which has biological tissue scaffolds as occlusion shells, for the percutaneous transluminal treatment of an intracardiac defect. The intracardiac occluder includes a proximal support structure (24) supporting the proximal occlusion shell (18) and a distal support structure (34) supporting the distal occlusion shell (20). In one embodiment, biological tissue derived from the tunica submucosa layer of the porcine small intestine forms the occlusion shells.

4. 发明公开

EP1165174A4 FREE STANDING FILTER 审中-公开
标题翻译： FREISTEHENDER过滤器
公开(公告)号：EP1165174A4
公开(公告)日：2006-08-30
申请号：EP00915773
申请日：2000-03-16
申请人： NMT MEDICAL INC
发明人： KLESHINSKI STEPHEN J
IPC分类号： A61B17/00 , A61F2/01 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067
摘要： A free standing filter (40) is provided with a filter body (48) having an elongate guide wire receiving member (50) extending centrally therethrough to define an open-ended channel configured to receive a plurality of different sized guide wires. An expandable, and contractible frame (44) surrounds the elongate guide wire receiving member (50), which is connected at a proximal end to the elongate guide wire receiving member. A porous embolic capturing unit (42) has an open-end connected to the frame (44), and a closed end connected to the elongate guide wire receiving member (60) which extends through the porous embolic capturing unit (42).

5. 发明公开

EP1487353A2 PATENT FORAMEN OVALE (PFO) CLOSURE CLIPS 审中-公开
标题翻译：专利故障OVALE（PFO）关闭CLIPS
公开(公告)号：EP1487353A2
公开(公告)日：2004-12-22
申请号：EP03716812.7
申请日：2003-03-25
申请人： NMT Medical, Inc.
发明人： PEAVEY, Todd, A. , FORDE, Sean, T. , CHANDUSZKO, Andrzej, J. , CALLAGHAN, David, J.
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/083 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867
摘要： The clips (18) of the present invention include two closure members (22, 24) joined by at least two spaced central connecting members (36, 38). The clips (18) are designed such that the at least two central connecting members (36, 38) extend through the inclined PFO tunnel and the two closure members (22, 24) compress the overlapping layers of septal tissue, i.e. septum primum and septum secundum, together to close the PFO tunnel. The clips (18) of the present invention take various forms depending, in part upon the distribution of force required to close a given PFO. Thus, embodiments of the closure members (22, 24) include arcuate peaks (26), loops (46, 48), and prongs (96, 98). In yet other embodiments, the closure members (22, 24) include centering elements (49) for centering the device in the desired delivery location and a tissue scaffold (108).
摘要翻译：本发明的夹子（18）包括由至少两个隔开的中央连接构件（36,38）连接的两个闭合构件（22,24）。夹子（18）被设计成使得至少两个中央连接构件（36,38）延伸穿过倾斜的PFO通道并且两个闭合构件（22,24）压缩隔膜组织的重叠层，即隔膜和隔膜继续共同关闭PFO隧道。本发明的夹子（18）部分取决于关闭给定PFO所需的力的分布而采取各种形式。因此，封闭构件（22,24）的实施例包括弧形峰（26），环（46,48）和叉（96,98）。在又一些实施例中，闭合构件（22,24）包括用于将设备定心在期望的递送位置中的定心元件（49）和组织支架（108）。

6. 发明公开

EP1467661A2 SEPTAL OCCLUDER AND ASSOCIATED METHODS 审中-公开
标题翻译：双侧封闭器和相关方法
公开(公告)号：EP1467661A2
公开(公告)日：2004-10-20
申请号：EP02795975.8
申请日：2002-12-19
申请人： NMT Medical, Inc.
发明人： RYAN, Carol, A. , CHANDUSZKO, Andrzej, J.
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/0475 , H04M1/68 , H04M1/723 , H04M1/72505 , H04W84/14
摘要： Devices are provided for closing septal defects such as PFOs. The devices generally include a proximal anchor member (52), a distal anchor member (54), and a flexible center joint (56) connecting the two anchor members.
摘要翻译：提供器件用于封闭诸如PFO的间隔缺陷。该装置通常包括近端锚定构件52，远端锚定构件54和连接两个锚定构件的柔性中心接头56。

7. 发明公开

EP1165174A1 FREE STANDING FILTER 审中-公开
标题翻译：自立式过滤器
公开(公告)号：EP1165174A1
公开(公告)日：2002-01-02
申请号：EP00915773.6
申请日：2000-03-16
申请人： NMT Medical, Inc.
发明人： KLESHINSKI, Stephen, J.
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067
摘要： A free standing filter (40) is provided with a filter body (48) having an elongate guide wire receiving member (50) extending centrally therethrough to define an open-ended channel configured to receive a plurality of different sized guide wires. An expandable, and contractible frame (44) surrounds the elongate guide wire receiving member (50), which is connected at a proximal end to the elongate guide wire receiving member. A porous embolic capturing unit (42) has an open-end connected to the frame (44), and a closed end connected to the elongate guide wire receiving member (60) which extends through the porous embolic capturing unit (42).

8. 发明公开

EP1164945A1 GRIPPING DEVICE FOR IMPLANTING, REPOSITIONING OR EXTRACTING AN OBJECT WITHIN A BODY VESSEL 有权
标题翻译：交叉单元植入于一体的船只重新定位或提取对象
公开(公告)号：EP1164945A1
公开(公告)日：2002-01-02
申请号：EP00914934.5
申请日：2000-03-20
申请人： NMT Medical, Inc.
发明人： RAVENSCROFT, Adrian, C.
IPC分类号： A61B17/28
CPC分类号： A61B17/50 , A61B17/22031 , A61B17/221 , A61B2017/2215 , A61F2/01 , A61F2002/011
摘要： A gripping device (10) is operative within a body vessel which includes an elongate, flexible support body (12) having a plurality of spaced gripping members (22) attached to the support body to extend axially outwardly from the outer end thereof. The gripping members are formed to have an expansion position where they angle laterally from the support body. A cone shaped flexible liner (34) forming an open ended enclosure in the expansion position of the gripping members has an outer end connected to the distal ends (26) of the gripping members, and an inner end connected to the support body. The flexible liner is surrounded by the gripping members.

9. 发明授权

EP1660167B1 Expandable sheath tubing 有权
标题翻译：展开鞘管
公开(公告)号：EP1660167B1
公开(公告)日：2008-11-12
申请号：EP04781644.2
申请日：2004-08-19
申请人： NMT Medical, Inc.
发明人： WRIGHT, John, A., Jr. , PEAVEY, Todd, A. , KOLBER, Andrea, B. , CORE, Lee, A.
IPC分类号： A61M25/00 , A61B17/34 , A61F2/06
CPC分类号： A61M25/0074 , A61B17/22031 , A61B17/3415 , A61B17/3439 , A61B17/3468 , A61B90/40 , A61B2017/1205 , A61B2090/08021 , A61F2/95 , A61F2/97 , A61F2002/011 , A61F2002/9528 , A61F2002/9534 , A61M25/0045 , A61M25/005 , A61M25/008 , A61M29/02 , A61M2025/0024 , A61M2025/0063 , A61M2025/0081 , A61M2025/1068 , A61M2025/1072 , A61M2025/1075 , A61M2025/1081
摘要： An expandable catheter (10) accommodates a medical device that is being removed from a body with a larger diameter than the catheter. The same catheter may be used to reposition a device within the body to an alternative delivery site. A catheter or sheath may be used to deliver a medical device, surgical instrument, or biological sample.

10. 发明授权

EP1542593B9 SEPTAL PUNCTURE DEVICE 有权转让
标题翻译： DEVICE穿刺隔膜
公开(公告)号：EP1542593B9
公开(公告)日：2008-08-20
申请号：EP03754499.6
申请日：2003-09-11
申请人： NMT Medical, Inc.
发明人： CHANDUSZKO, Andrzej , CALLAGHAN, David, J. , WIDOMSKI, David
IPC分类号： A61B17/02
CPC分类号： A61B17/0057 , A61B17/0218 , A61B17/30 , A61B17/32053 , A61B17/3478 , A61B2017/00247 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2018/00392
摘要： Apparatus, systems, and methods for forming a hole in biological material, such as tissue walls, adjacent vessels or adjacent regions of an organ such that access to opposing surfaces of the biological material can be achieved. In general overview the system may include ,an elongate member for positioning and deploying a flexible member in the heart. In one embodiment apparatus and methods are provided for aligning and fixing the position of the tip of a cutting member for cutting a hole in the septal wall of a heart. In another embodiment, subsequent to cutting a tissue wall an apparatus for obstructing holes in the septal wall is inserted to limit the flow of blood through a plurality of holes in a tissue wall.

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