专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP4257127A1 EMULSION COMPOSITION FOR EXTERNAL USE 失效
公开(公告)号：EP4257127A1
公开(公告)日：2023-10-11
申请号：EP21900691.3
申请日：2021-12-03
申请人： Maruho Co., Ltd.
发明人： SUZUKI Satoko , MAEDA Mayumi
IPC分类号： A61K31/327 , A61K9/10 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/44 , A61P17/00 , A61P17/10
摘要： Provided is a skin composition which can reduce side effects of skin drying caused due to benzoyl peroxide and can keep benzoyl peroxide stable.
An emulsion topical composition for skin, containing:
(A) benzoyl peroxide;
(B) 0.3 to 12.5 wt.% of at least one liquid oil having an α value of 0° to 8°;
(C) 0.3 to 2.5 wt.% of at least one solid oil;
(D) at least one aqueous solvent; and
(E) at least one surfactant.

2. 发明公开

EP4194018A1 SKIN COMPOSITION 审中-实审
公开(公告)号：EP4194018A1
公开(公告)日：2023-06-14
申请号：EP21852270.4
申请日：2021-08-04
申请人： Maruho Co., Ltd.
发明人： NAKAMURA Yuki , ISHIGAME Takayoshi , YAMAKOSHI Wataru
IPC分类号： A61L26/00 , A61K47/32
摘要： The present invention relates to a film-forming skin composition containing (a1) an ethyl acrylate-methyl methacrylate-trimethylammonium ethyl methacrylate chloride copolymer, and (a2) an ethyl acrylate-methyl methacrylate copolymer. The film formed from the composition of the present invention has high water resistance and/or high friction resistance. Meanwhile, this film can be easily washed off from the skin.

3. 发明公开

EP3549586A1 MEDICAL SKIN EXTERNAL PREPARATION 审中-公开
公开(公告)号：EP3549586A1
公开(公告)日：2019-10-09
申请号：EP17876674.7
申请日：2017-11-30
申请人： Maruho Co., Ltd.
发明人： SAKAGUCHI, Tomoki , KAWAGUCHI, Masumi , NAKAMURA, Ayako
IPC分类号： A61K31/4709 , A61K9/06 , A61K47/10 , A61K47/12 , A61P17/00 , A61P17/04 , A61P17/10 , A61P31/04
摘要： An object of the present invention is mainly to provide a medical skin external preparation that is suitable for treating superficial skin infections, in particular, superficial skin infections accompanied by blister or erosion, etc. For example, the present invention can provide a medical skin external preparation containing 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof as an active ingredient, and an alcohol and/or a fatty acid having 12 or more carbon atoms.

4. 发明公开

EP3257512A1 EXTERNAL PREPARATION COMPRISING PYRIDONECARBOXYLIC ACID DERIVATIVE 审中-公开
标题翻译：包含吡啶基十六烷酸衍生物的外用制剂
公开(公告)号：EP3257512A1
公开(公告)日：2017-12-20
申请号：EP16749300.6
申请日：2016-02-12
申请人： Maruho Co., Ltd.
发明人： FUJIKAWA, Akira , YAMADA, Hiroshi
IPC分类号： A61K31/4709 , A61K9/06 , A61K9/08 , A61K9/10 , A61K9/70 , A61K47/10 , A61K47/38 , A61P17/00 , A61P17/02 , A61P17/10 , A61P31/04
CPC分类号： A61K31/4709 , A61K9/0014 , A61K9/06 , A61K47/10 , A61K47/38 , A61P17/10
摘要： The purpose of the present invention is to provide an external preparation which exerts a therapeutic and/or prophylactic effect on infectious diseases in the field of dermatology such as acne accompanied by suppurative inflammation or epidermal skin infectious diseases when administered once a day mainly to a human patient. As an example of the external preparation according to the present invention, an external preparation, which is characterized by comprising as an active ingredient 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolincarboxylic acid and/or a pharmaceutically acceptable salt thereof and exerting a therapeutic and/or prophylactic effect on infectious diseases in the field of dermatology when administered once a day to a human patient, can be cited.
摘要翻译：本发明的目的在于提供一种对皮肤病学领域的感染性疾病，例如伴有化脓性炎症的痤疮或表皮皮肤感染性疾病，主要对人类每天给药一次时发挥治疗和/或预防作用的外用制剂患者。作为本发明的外用剂的一个例子，特征在于含有作为有效成分的1-环丙基-8-甲基-7- [5-甲基-6-（甲基氨基）-3-吡啶基 ] -4-氧代-1,4-二氢-3-喹啉羧酸和/或其药学上可接受的盐，并且当对人类患者每天给药一次时，对皮肤病学领域的感染性疾病发挥治疗和/或预防作用，可以引用。

5. 发明公开

EP2671568A1 DERMAL COMPOSITION COMPRISING POLYMERIC REVERSED MICELLE, AND METHOD FOR PRODUCING SAME 审中-公开
标题翻译： DERMALE ZUSAMMENSETZUNG MIT EINER UMGEKEHRTEN POLYMEREN MIZELLE UND HERSTELLUNGSVERFAHRENDAFÜR
公开(公告)号：EP2671568A1
公开(公告)日：2013-12-11
申请号：EP12741948.9
申请日：2012-01-30
申请人： MARUHO Co., Ltd.
发明人： AKAMATSU, Ryo , SAKAGUCHI, Tomoki , SAKIYAMA, Hiroki
IPC分类号： A61K9/107 , A61K47/06 , A61K47/10 , A61K47/14 , A61K47/34 , B01J13/00
CPC分类号： A61K9/0014 , A61K9/1075 , A61K47/10 , A61K47/14 , A61K47/44 , B01J13/02
摘要： The present invention provides a dermal composition comprising a polymeric reversed micelle that allows a water-soluble drug to be efficiently encapsulated and that is superior in percutaneous absorptiveness and very safe, and provides a method that can produce the composition in simple steps. The dermal composition comprises a polymeric reversed micelle composed of an amphipathic polymer having a hydrophilic segment and a hydrophobic segment, wherein the polymeric reversed micelle has a configuration in which the hydrophilic segment is the core and the hydrophobic segment is the shell, and a water-soluble drug is encapsulated therein. The composition can be produced by blending an oil phase comprising the amphipathic polymer in an oily base agent with an aqueous phase comprising the water-soluble drug in an aqueous solvent, or by blending an oily base agent with an aqueous phase comprising the amphipathic polymer and the water-soluble drug in an aqueous solvent.
摘要翻译：本发明提供一种包含聚合物反胶束的真皮组合物，其允许水溶性药物被有效地包封，并且经皮吸收性优异且非常安全，并且提供了可以以简单步骤制备组合物的方法。所述真皮组合物包含由具有亲水链段和疏水链段的两亲性聚合物组成的聚合物反胶束，其中所述聚合物反胶束具有其中亲水链段为核并且疏水链段为壳的构型，可溶性药物被包封在其中。组合物可以通过将油性基剂中包含两亲性聚合物的油相与包含水溶性药物的水相混合在水性溶剂中，或通过将油性基剂与包含两亲性聚合物的水相混合，该水溶性药物在水性溶剂中。

6. 发明公开

EP2198887A1 THERAPEUTIC AGENT FOR LEUKODERMA AND METHOD FOR ACCELERATION OF PIGMENTATION 审中-公开
标题翻译：维多利亚州立大学维多利亚州立大学
公开(公告)号：EP2198887A1
公开(公告)日：2010-06-23
申请号：EP08838612.3
申请日：2008-10-17
申请人： The University of Tokyo , MARUHO Co., Ltd.
发明人： TAMAKI, Kunihiko , KIKUCHI, Kanako , KOMINE, Mayumi , FUJIMOTO, Seiki
IPC分类号： A61K45/00 , A61K31/416 , A61K31/593 , A61K31/7076 , A61K33/18 , A61K38/27 , A61P17/00
CPC分类号： A61K31/416 , A61K31/56 , A61K31/593 , A61K31/7076 , A61K33/18 , A61K38/27 , A61K41/0057 , A61K45/06 , A61K2300/00
摘要： Provided are a pharmaceutical product capable of treating vitiligo by thickening the epidermis at a vitiligo-affected site, which has been thinned, to thereby accelerate pigmentation, and a method of accelerating pigmentation by thickening the epidermis.
Vitiligo can be treated by using a compound having an epidermis thickening action, for example, a therapeutic agent for a skin ulcer which is used in the treatment of burn ulcer, crural ulcer, diabetic ulcer or post-operative ulcer, or a therapeutic agent for bedsore.
摘要翻译：本发明提供能够通过在已经变薄的白癜风影响部位增厚表皮来治疗白癜风的药物，从而加速色素沉着，以及通过增厚表皮来促进色素沉着的方法。可以通过使用具有表皮增厚作用的化合物治疗白癜风，例如用于治疗烧伤性溃疡，溃疡性溃疡，糖尿病性溃疡或手术后溃疡的皮肤溃疡治疗剂，或治疗剂褥疮。

7. 发明公开

EP1369127A1 NOVEL MEDICINAL USE OF APLPHA ANTIGEN OR ALPHA ANTIGEN GENE 有权
标题翻译： NEE MEDISINISCHE VERWENDUNG VON ALPHA-ANTIGEN ODER ALPHA-ANTIGEN-GEN
公开(公告)号：EP1369127A1
公开(公告)日：2003-12-10
申请号：EP02700618.8
申请日：2002-02-20
申请人： MARUHO Co., Ltd.
发明人： YASUTOMI, Yasuhiro , MIZUTANI, Hitoshi
IPC分类号： A61K39/04 , A61K31/711 , A61P37/08 , A61P27/00 , A61P11/06 , A61P27/16
CPC分类号： A61K39/04 , A61K2039/53
摘要： The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of allergic diseases such as IgE production, histamine release and eosinophil infiltration, and therefore they are very effective for the prevention or treatment of atopic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis, and more broadly allergic diseases.
摘要翻译： α抗原编码基因和α抗原蛋白抑制白细胞介素-4等的产生，改善Th2型细胞因子主导状态，进而抑制IgE产生，组胺释放和嗜酸性粒细胞浸润等过敏性疾病的各种病症，因此它们对预防或治疗特应性皮炎，哮喘，过敏性鼻炎和过敏性结膜炎等特应性疾病以及更广泛的过敏性疾病非常有效。

8. 发明公开

EP1312675A1 PROTEIN INDUCED BY HOMOGENEOUS BLOOD TRANSFUSION AND DNA ENCODING THE SAME 有权
标题翻译： DURCH HOMOGENE BLUTTRANSFUSION INDUZIERTES PROTEIN UNDFüRDIESES KODIERENDE DNA
公开(公告)号：EP1312675A1
公开(公告)日：2003-05-21
申请号：EP01956777.5
申请日：2001-08-01
申请人： MARUHO Co., Ltd.
发明人： UCHIDA, Hiroo, Koshigaya Familytown C115 , TANAKA, Hirokazu, Maruho Co. Ltd. , KITOH, Yasuhiko, Maruho Co. Ltd. , FUJIMURA, Akio , KOBAYASHI, Eiji
IPC分类号： C12N15/12 , C12N1/21 , C12N5/10 , C07K14/47 , C12P21/02 , A61K38/17 , A61P11/06 , A61P17/00 , A61P17/06 , A61P27/16 , A61P29/00 , A61P37/06 , A61P37/08
CPC分类号： C07K14/8114 , A61K38/00 , C07K14/811
摘要： The present invention relates to a novel protein (MAY-I) which exhibits immunosuppressive activity in allogeneic mixed lymphocyte reaction, and provides a gene encoding that protein, a vector containing said gene, a transformant produced by said vector, a method of manufacturing the said protein with immune activity by culturing said transformant, and a medicinal composition and the like containing the said protein.
摘要翻译：本发明涉及在同种异体混合淋巴细胞反应中表现出免疫抑制活性的新型蛋白质（MAY-1），提供了编码该蛋白质的基因，含有该基因的载体，由该载体产生的转化体，通过培养所述转化体具有免疫活性的蛋白质和含有所述蛋白质的药物组合物等。

9. 发明公开

EP4252771A1 INHIBITOR OF FIBROSIS PROGRESSION 失效
公开(公告)号：EP4252771A1
公开(公告)日：2023-10-04
申请号：EP21898137.1
申请日：2021-11-29
申请人： Maruho Co., Ltd. , The University of Tokyo
发明人： YOSHIZAKI, Ayumi , KUZUMI, Ai , SATO, Shinichi , FUJITA, Tomoyuki , WATANABE, Hideki
IPC分类号： A61K39/395 , A61P17/00
摘要： In one embodiment, the present disclosure provides pharmaceutical compositions for suppressing the progression of fibrosis in systemic sclerosis, which contain an antibody against IL-31 receptor A as an active ingredient. In another embodiment, the present disclosure provides pharmaceutical compositions for suppressing Th2 polarization to suppress the progression of fibrosis in systemic sclerosis, which comprise an antibody against IL-31 receptor A as an active ingredient. In a certain embodiment, the above-mentioned antibody is an antibody having a neutralizing activity against IL-31 receptor A.

10. 发明授权

EP1941880B1 LOTION PREPARATION CONTAINING PYRIDONECARBOXYLIC ACID DERIVATIVE 有权
标题翻译：一个吡衍生物基LOTION
公开(公告)号：EP1941880B1
公开(公告)日：2015-10-28
申请号：EP06782007.6
申请日：2006-07-31
申请人： MARUHO Co., Ltd.
发明人： HIROTA, Tsuyoshi c/o Maruho Co., Ltd.
IPC分类号： A61K31/4709 , A61K9/08 , A61K47/10 , A61K47/30 , A61K47/38 , A61P17/00 , A61P31/04
CPC分类号： A61K47/10 , A61K9/0014 , A61K31/4709

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式