专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP2073836A4 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VAGINAL DISEASES EMPLOYING PEROXIDE-PRODUCING ENZYMES AND PEROXIDASES 审中-公开
标题翻译：方法和组合物治疗VAGINALERKRANKUNGEN用过氧化物酶PRODUCING和过氧化物
公开(公告)号：EP2073836A4
公开(公告)日：2010-04-07
申请号：EP07815021
申请日：2007-09-28
申请人： LACLEDE INC
发明人： PELLICO MICHAEL , ATWAL RAJVINDER KAUR
IPC分类号： A61K38/54
CPC分类号： A61K38/44 , A61K9/0034 , A61K31/19 , A61K31/375 , A61K31/573 , A61K31/58 , A61K33/40 , A61K38/40 , A61K38/443 , A61K38/47 , A61K45/06 , A61K47/10 , A61K47/44 , C12Y101/03004 , C12Y111/01007 , C12Y111/02002 , A61K2300/00
摘要： A therapeutic composition for vaginal administration based on the generation of a biocidal anion by an enzymatic reaction catalyzed by a peroxidase. The peroxide utilized by the peroxidase enzyme can be endogenous or can be generated by the action of an oxidase enzyme on a suitable substrate. Therapeutic compositions according to the present invention are useful for the treatment of vaginal diseases and conditions, including bacterial and fungal infections.

2. 发明公开

EP2016187A4 COMPOSITIONS AND METHODS FOR ENZYMATIC TREATMENT OF LUNG DISORDERS 有权
标题翻译：成分和方法酶处理肺病
公开(公告)号：EP2016187A4
公开(公告)日：2012-01-04
申请号：EP07783598
申请日：2007-05-10
申请人： LACLEDE INC
发明人： PELLICO MICHAEL , BOSCO PAMELA
IPC分类号： A61K38/44
CPC分类号： A61K38/44 , A61K9/007 , A61K31/375 , A61K31/573 , A61K38/40 , A61K38/443 , A61K38/47 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/26 , C12Y101/03004 , C12Y101/03009 , C12Y101/03017 , C12Y111/01007 , C12Y111/02002 , C12Y302/01017 , A61K2300/00

3. 发明公开

EP2939687A1 USE OF HYDROLYTIC ENZYMES TO DISSOLVE BIOFILM IN EARS 审中-公开
标题翻译：维尔伍德VON水溶性环氧酶ZOHAUFLÖSENVON BIOFILMEN OHREN
公开(公告)号：EP2939687A1
公开(公告)日：2015-11-04
申请号：EP15167603.8
申请日：2007-11-07
申请人： Laclede, Inc.
发明人： Pellico, Michael
IPC分类号： A61K38/47 , A61K38/44 , A61K31/573 , A61K31/58
CPC分类号： A61K38/47 , A61K9/0046 , A61K9/0053 , A61K31/573 , A61K31/58 , A61K38/40 , A61K38/44 , A61K38/443 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/38 , C12Y101/03004 , C12Y111/01007 , C12Y302/01004 , C12Y302/01008 , C12Y302/01017 , C12Y302/01022 , A61K2300/00
摘要： A composition for removal of biofilm in the ears is useful for the treatment of ear infections such as otitis media, particularly those infections caused by Pseudomonas aeruginosa. In general, the composition comprises: (1) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the ear; and (2) a pharmaceutically acceptable carrier suitable for administration into the ear canal. The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an ear infection based on the ability of the composition to dissolve biofilm in the ear.
摘要翻译：用于去除耳朵中生物膜的组合物可用于治疗耳朵感染如中耳炎，特别是由铜绿假单胞菌引起的感染。通常，组合物包含：（1）一定量的至少一种酶，其催化连接多糖中的两个单糖的键的水解，或者连接单糖与糖蛋白中的蛋白质分子，足以分解生物膜中的生物膜耳; 和（2）适于施用于耳道的药学上可接受的载体。该组合物可进一步包括成分，例如类固醇，溶菌酶，乳铁蛋白或过氧化物酶; 如果包括过氧化物酶，组合物还可以包括氧化酶以产生过氧化物以及用于氧化酶的底物。该组合物可用于基于组合物将生物膜溶解在耳朵中的能力来治疗耳朵感染的方法。

4. 发明授权

EP2099466B1 USE OF HYDROLYTIC AND OXIDATIVE ENZYMES TO DISSOLVE BIOFILM IN EARS 有权转让
标题翻译：水解和氧化酶BIOFIMEN的耳朵的分辨率，使用
公开(公告)号：EP2099466B1
公开(公告)日：2015-06-03
申请号：EP07864012.5
申请日：2007-11-07
申请人： Laclede, Inc.
发明人： PELLICO, Michael
IPC分类号： A61K38/00 , A61K38/44 , A61K38/47 , A61K47/10 , A61P31/04
CPC分类号： A61K38/47 , A61K9/0046 , A61K9/0053 , A61K31/573 , A61K31/58 , A61K38/40 , A61K38/44 , A61K38/443 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/38 , C12Y101/03004 , C12Y111/01007 , C12Y302/01004 , C12Y302/01008 , C12Y302/01017 , C12Y302/01022 , A61K2300/00

5. 发明公开

EP2175864A4 USE OF HYDROLYTIC AND OXIDATIVE ENZYMES TO DISSOLVE BIOFILM IN AIRWAY PASSAGES 审中-公开
标题翻译：水解和氧化酶生物膜的解决方案呼吸道感染中的应用
公开(公告)号：EP2175864A4
公开(公告)日：2010-10-27
申请号：EP08728153
申请日：2008-01-23
申请人： LACLEDE INC
发明人： PELLICO MICHAEL A
IPC分类号： A61K31/715 , A61K38/47 , A61K38/54 , A61P31/04 , A61P31/10
CPC分类号： A61K38/54 , A61K31/573 , A61K38/40 , A61K38/44 , A61K38/443 , A61K38/465 , A61K38/47 , A61K45/06 , C12Y111/01007 , C12Y302/01 , C12Y302/01011 , C12Y302/01015 , C12Y302/01017 , A61K2300/00
摘要： A composition for removal of biofilm in the airway passage is useful for the treatment of infections such as pneumonia cause by Mycoplasma pneumoniae. In general, the composition comprises: (1) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the airway; and (2) a pharmaceutically acceptable carrier suitable for administration into the airway. The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an infection based on the ability of the composition to dissolve biofilm in the airway.

6. 发明公开

EP2016187A2 COMPOSITIONS AND METHODS FOR ENZYMATIC TREATMENT OF LUNG DISORDERS 有权
标题翻译：组合物中的在酶处理肺病
公开(公告)号：EP2016187A2
公开(公告)日：2009-01-21
申请号：EP07783598.1
申请日：2007-05-10
申请人： Laclede, Inc.
发明人： PELLICO, Michael , BOSCO, Pamela
IPC分类号： C12Q1/28
CPC分类号： A61K38/44 , A61K9/007 , A61K31/375 , A61K31/573 , A61K38/40 , A61K38/443 , A61K38/47 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/26 , C12Y101/03004 , C12Y101/03009 , C12Y101/03017 , C12Y111/01007 , C12Y111/02002 , C12Y302/01017 , A61K2300/00
摘要： A therapeutic composition for the treatment of lung diseases or disorders and diseases or disorders of the airway passages including pneumonia, acute respiratory failure, and acute respiratory distress syndrome is based on the generation of a biocidal anion by an enzymatic reaction catalyzed by a peroxidase. The peroxide utilized by the peroxidase enzyme can be endogenous or can be generated by the action of an oxidase enzyme on a suitable substrate.

7. 发明公开

EP3810066A1 METHODS, COMPOSITIONS AND DEVICES RELATED TO SEAWEED MASKS 审中-实审
公开(公告)号：EP3810066A1
公开(公告)日：2021-04-28
申请号：EP19825727.1
申请日：2019-06-25
申请人： Laclede, Inc.
发明人： PELLICO, Michael
IPC分类号： A61K8/06 , A61K8/19 , A61K8/72

8. 发明授权

EP2016187B1 COMPOSITIONS FOR USE IN THE ENZYMATIC TREATMENT OF LUNG DISORDERS 有权
标题翻译：组合物中的在酶处理肺病
公开(公告)号：EP2016187B1
公开(公告)日：2016-07-06
申请号：EP07783598.1
申请日：2007-05-10
申请人： Laclede, Inc.
发明人： PELLICO, Michael , BOSCO, Pamela
IPC分类号： A61K38/44
CPC分类号： A61K38/44 , A61K9/007 , A61K31/375 , A61K31/573 , A61K38/40 , A61K38/443 , A61K38/47 , A61K45/06 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/26 , C12Y101/03004 , C12Y101/03009 , C12Y101/03017 , C12Y111/01007 , C12Y111/02002 , C12Y302/01017 , A61K2300/00

9. 发明公开

EP2099466A4 USE OF HYDROLYTIC AND OXIDATIVE ENZYMES TO DISSOLVE BIOFILM IN EARS 有权转让
标题翻译： VERWENDUNG VON HYDROLYTISCHEN UND OZIDATIVEN ENZYMEN ZURAUFLÖSUNGVON BIOFIMEN在OHREN
公开(公告)号：EP2099466A4
公开(公告)日：2012-04-11
申请号：EP07864012
申请日：2007-11-07
申请人： LACLEDE INC
发明人： PELLICO MICHAEL
IPC分类号： A61K38/00 , A61K38/44 , A61K38/47 , A61K47/10 , A61P31/04
CPC分类号： A61K38/47 , A61K9/0046 , A61K9/0053 , A61K31/573 , A61K31/58 , A61K38/40 , A61K38/44 , A61K38/443 , A61K45/06 , A61K47/06 , A61K47/10 , A61K47/38 , C12Y101/03004 , C12Y111/01007 , C12Y302/01004 , C12Y302/01008 , C12Y302/01017 , C12Y302/01022 , A61K2300/00
摘要： A composition for removal of biofilm in the ears is useful for the treatment of ear infections such as otitis media, particularly those infections caused by Pseudomonas aeruginosa. In general, the composition comprises: (1) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the ear; and (2) a pharmaceutically acceptable carrier suitable for administration into the ear canal. The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an ear infection based on the ability of the composition to dissolve biofilm in the ear.
摘要翻译：用于去除耳朵中生物膜的组合物可用于治疗耳朵感染如中耳炎，特别是由铜绿假单胞菌引起的感染。通常，组合物包含：（1）一定量的至少一种酶，其催化连接多糖中的两个单糖的键的水解，或者连接单糖与糖蛋白中的蛋白质分子，足以分解生物膜中的生物膜耳; 和（2）适于施用于耳道的药学上可接受的载体。该组合物可进一步包括成分，例如类固醇，溶菌酶，乳铁蛋白或过氧化物酶; 如果包括过氧化物酶，组合物还可以包括氧化酶以产生过氧化物以及用于氧化酶的底物。该组合物可用于基于组合物将生物膜溶解在耳朵中的能力来治疗耳朵感染的方法。

10. 发明公开

EP2175864A2 USE OF HYDROLYTIC AND OXIDATIVE ENZYMES TO DISSOLVE BIOFILM IN AIRWAY PASSAGES 审中-公开
标题翻译：水解和氧化酶在气道通道中溶解生物膜的应用
公开(公告)号：EP2175864A2
公开(公告)日：2010-04-21
申请号：EP08728153.1
申请日：2008-01-23
申请人： Laclede, Inc.
发明人： PELLICO, Michael, A.
IPC分类号： A61K31/715
CPC分类号： A61K38/54 , A61K31/573 , A61K38/40 , A61K38/44 , A61K38/443 , A61K38/465 , A61K38/47 , A61K45/06 , C12Y111/01007 , C12Y302/01 , C12Y302/01011 , C12Y302/01015 , C12Y302/01017 , A61K2300/00
摘要： A composition for removal of biofilm in the airway passage is useful for the treatment of infections such as pneumonia cause by Mycoplasma pneumoniae. In general, the composition comprises: (1) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the airway; and (2) a pharmaceutically acceptable carrier suitable for administration into the airway. The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an infection based on the ability of the composition to dissolve biofilm in the airway.
摘要翻译：用于去除气道中生物膜的组合物可用于治疗由肺炎支原体引起的肺炎等感染。通常，组合物包含：（1）一定量的至少一种酶，其催化连接多糖中连接两个单糖或将单糖与糖蛋白中的蛋白质分子连接的键的水解，所述糖蛋白中足以分解生物膜中的生物膜气道; 和（2）适于施用到气道中的药学上可接受的载体。所述组合物可进一步包含诸如类固醇，溶菌酶，乳铁蛋白或过氧化物酶的成分; 如果包含过氧化物酶，组合物可以进一步包括产生过氧化物的氧化酶以及氧化酶的底物。基于组合物在气道中溶解生物膜的能力，组合物可用于治疗感染的方法中。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式