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1. 发明公开

EP4375377A1 SUBSTANCE DETECTION METHOD USING AMINOACYLASE 审中-公开
公开(公告)号：EP4375377A1
公开(公告)日：2024-05-29
申请号：EP22845757.8
申请日：2022-06-29
申请人： Josho Gakuen Educational Foundation , Nipro Corporation
发明人： NISHIYA, Yoshiaki , TATSUMI, Kenta , YAGURA, Kazuki
IPC分类号： C12N15/55 , C12Q1/34 , C12N9/80
CPC分类号： C12Q1/34 , C12N9/80 , C12N9/14
摘要： At least the presence of a starting material is detected by measuring glycine formed as a by-product along with a main product through a chemical reaction involving hippuric acid and/or methylhippuric acid as the starting material and catalyzed by a hydrolase. The hydrolase is an aminoacylase having an amino acid sequence of SEQ ID NO: 1 or a protein having the amino acid sequence of SEQ ID NO: 1 in which one or more amino acids are deleted, replaced, or added and having activity for hydrolysis of the hippuric acid and the methylhippuric acid.

2. 发明授权

EP2905351B1 HYPEREUTECTIC ALUMINUM/SILICON ALLOY DIE-CAST MEMBER AND PROCESS FOR PRODUCING SAME 有权
标题翻译：超合金铝/硅合金模铸件及其生产方法
公开(公告)号：EP2905351B1
公开(公告)日：2017-11-01
申请号：EP13842276.1
申请日：2013-09-24
申请人： Josho Gakuen Educational Foundation
发明人： HAGA, Toshio , FUSE, Hiroshi
IPC分类号： C22C21/02 , B22D17/00 , B22D17/30 , B22D21/04
CPC分类号： C22C21/02 , B22D17/10 , B22D17/30 , B22D21/007 , B22D21/04 , C22C21/04 , Y10T428/12
摘要： The present invention provides a hypereutectic aluminum-silicon alloy die-cast member which contains 20.0% by mass to 30.0% by mass of silicon and also has a thickness of 2.5 mm or less, and a method for producing the same. Disclosed is a die-cast member made of a hypereutectic aluminum-silicon alloy containing 20.0% by mass to 30.0% by mass of silicon, wherein the die-cast member has a thickness of 2.5 mm or less and an average size of primary crystal Si is 0.04 mm to 0.20 mm.

3. 发明公开

EP2905351A1 HYPEREUTECTIC ALUMINUM/SILICON ALLOY DIE-CAST MEMBER AND PROCESS FOR PRODUCING SAME 有权
标题翻译：其制造铝/硅合金和方法过共晶铸件中
公开(公告)号：EP2905351A1
公开(公告)日：2015-08-12
申请号：EP13842276.1
申请日：2013-09-24
申请人： Josho Gakuen Educational Foundation
发明人： HAGA, Toshio , FUSE, Hiroshi
IPC分类号： C22C21/02 , B22D17/00 , B22D17/30 , B22D21/04
CPC分类号： C22C21/02 , B22D17/10 , B22D17/30 , B22D21/007 , B22D21/04 , C22C21/04 , Y10T428/12
摘要： The present invention provides a hypereutectic aluminum-silicon alloy die-cast member which contains 20.0% by mass to 30.0% by mass of silicon and also has a thickness of 2.5 mm or less, and a method for producing the same.
Disclosed is a die-cast member made of a hypereutectic aluminum-silicon alloy containing 20.0% by mass to 30.0% by mass of silicon, wherein the die-cast member has a thickness of 2.5 mm or less and an average size of primary crystal Si is 0.04 mm to 0.20 mm.

4. 发明公开

EP2839779A1 VEHICLE-USE SEAT 审中-公开
标题翻译：车用座椅
公开(公告)号：EP2839779A1
公开(公告)日：2015-02-25
申请号：EP13778140.7
申请日：2013-04-18
申请人： TS Tech Co., Ltd. , Josho Gakuen Educational Foundation , Nihon University
发明人： SUGIYAMA, Shinji , NAKANO, Toyokazu , OHSUGA, Mieko , KOBAYASHI, Hiroyuki , YASUDA, Shota , KAGEYAMA, Ichiro , KURIYAGAWA, Yukiyo
IPC分类号： A61B5/0408 , A61B5/0428 , A61B5/0452 , A61B5/0478 , B60N2/44 , B60R21/015
CPC分类号： A61B5/18 , A61B5/0245 , A61B5/0402 , A61B5/0428 , A61B5/0456 , A61B5/6891 , A61B5/6893 , A61B5/7278 , B60N2/002 , B60N2/64
摘要： To make it possible to stably measure heartbeats even if seated persons physically differ and to measure the heartbeats of even a seated person other than a driver. A vehicle seat includes : a seat back (104) ; and a measuring device including a plurality of sensors (20A, 20B, 20C) that are provided in the seat back (104) and that acquire body potentials of the seated person, and an arithmetic operation device that computes electrical signals relating to the detected body potentials to obtain an electrocardiographic signal of the seated person. The sensors (20A, 20B, 20C) are each capacitively coupled sensors. The sensor (20A) is arranged at a lower right position relatively to the sensor (20B) and the sensor (20C) while facing a front surface of the seat back (104) if a surface of the seat back (104) facing the seated person is assumed as the front surface. The sensor (20A) and the sensor (20C) are arranged so that a heart of the seated person is located in a zone (20AC) if the zone (20AC) is defined from the sensor (20A) and the sensor (20C).
摘要翻译：即使坐着的人身体不同，也可以稳定地测量心跳，并测量驾驶员以外的坐着的人的心跳。一种车辆座椅，包括：座椅靠背（104）; 以及测量装置，该测量装置包括设置在座椅靠背（104）中并获取就座者的身体电位的多个传感器（20A，20B，20C）以及计算与检测到的身体有关的电信号的算术运算装置电位以获得就座者的心电图信号。传感器（20A，20B，20C）各自是电容耦合的传感器。如果座椅靠背（104）的面向就座的表面（10）面向座椅靠背（104）的前表面，则传感器（20A）布置在相对于传感器（20B）和传感器（20C）人被假定为前表面。如果由传感器（20A）和传感器（20C）限定区域（20AC），则传感器（20A）和传感器（20C）被布置为使得坐着的人的心脏位于区域（20AC）中。

5. 发明公开

EP4230223A1 COMPOSITION 审中-实审
公开(公告)号：EP4230223A1
公开(公告)日：2023-08-23
申请号：EP21880033.2
申请日：2021-10-11
申请人： Josho Gakuen Educational Foundation , ADEKA CORPORATION
发明人： SAKUMA Shinji , TOMONO Takumi , MIYATA Kohei , SHIGENO Koichi
IPC分类号： A61K47/34 , A61K39/395 , A61K47/32 , C07K7/00 , C07K14/00 , C07K16/00
摘要： The object of the present invention is to provide an absorption enhancer capable of introducing high-molecular weight compounds into cells.
The object can be solved by a composition of the present invention comprising a polymer compound having a group represented by the following general formula (1) or the following general formula (2) at a side chain, and a compound to be administered with a molecular weight of 1,000 to 1,200,000.

wherein X 1 is a residue of neutral amino acid or ω-aminoalkanoic acid in which an end amino group and an end carboxyl group are removed, X 2 is a residue of cell-penetrating peptide in which an end amino group and an end carboxyl group are removed, X 3 is a hydroxyl group, an amino group, an alkoxyl group having 1 to 4 carbon atoms or a benzyloxy group, a is an integer of 0 to 50, and * denotes a bonding site.
wherein X 4 is a residue of neutral amino acid or ω-aminoalkanoic acid in which an end amino group and an end carboxyl group are removed, X 5 is a residue of cell-penetrating peptide in which an end amino group and an end carboxyl group are removed, X 6 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a benzyl group, an acyl group having 1 to 6 carbon atoms, an arylsulfonyl group or an oxycarbonyl group, b is an integer of 0 to 50, and * denotes a bonding site.

6. 发明公开

EP3855597A1 WIRELESS ELECTRICAL POWER SUPPLY DEVICE 审中-公开
公开(公告)号：EP3855597A1
公开(公告)日：2021-07-28
申请号：EP19878887.9
申请日：2019-11-01
申请人： Nichicon Corporation , Josho Gakuen Educational Foundation
发明人： OMORI, Hideki , TSUNO, Masahito , YAMAGUCHI, Masashi
IPC分类号： H02J50/12 , H02J50/80 , H02J7/00 , B60L53/122
摘要： A wireless electrical power supply apparatus 100 includes a first electrical power supply unit 101, a second electrical power supply unit 104, voltage control circuits 113 and 123 configured to control a first voltage difference between a first input voltage E 1 and a first output voltage E 2 during forward power transmission and a second voltage difference between a second input voltage E 2 and a second output voltage E 1 during reverse power transmission, a second switching control circuit 121, 122 configured to turn off a second transistor Q 2 during the forward power transmission and thereby cause a second diode D 2 to perform rectification, and a first switching control circuit 111, 112 configured to turn off a first transistor Q 1 during the reverse power transmission and thereby cause a first diode D 1 to perform rectification.

7. 发明授权

EP3263582B1 POLYMER COMPOUND WHICH HAS MEMBRANE-PERMEABLE PEPTIDE IN SIDE CHAIN 有权
公开(公告)号：EP3263582B1
公开(公告)日：2019-08-14
申请号：EP16755452.6
申请日：2016-02-23
申请人： Josho Gakuen Educational Foundation , Adeka Corporation
发明人： SAKUMA, Shinji , MOHRI, Kohta , HIWATARI, Ken-ichiro , OCHIAI, Kyohei
IPC分类号： C07K2/00 , C08F8/30 , C08F220/06 , C08F220/56 , C08G81/00 , C08F226/02 , A61K47/32

8. 发明授权

EP2823833B1 BLOOD FEEDING FLOW RATE-CONTROLLING DEVICE AND EXTRACORPOREAL CIRCULATION DEVICE 有权
标题翻译：供血流量控制装置和体外循环设备
公开(公告)号：EP2823833B1
公开(公告)日：2017-03-08
申请号：EP13757242.6
申请日：2013-01-29
申请人： Hiroshima University , Josho Gakuen Educational Foundation
发明人： NINOMIYA, Shinji , SUEDA, Taijiro , KUROSAKI, Tatsuya , KUDO, Masaaki , OKAMURA, Naoya
IPC分类号： A61M1/10 , A61M1/14
CPC分类号： A61M1/1086 , A61M1/1006 , A61M1/101 , A61M1/3639 , A61M1/3663 , A61M1/3666 , A61M1/3667 , A61M2205/3334 , A61M2205/3351 , A61M2205/3355 , A61M2205/3365

9. 发明公开

EP2839779A4 VEHICLE-USE SEAT 审中-公开
标题翻译： SITZ ZUR VERWENDUNG在EINEM FAHRZEUG
公开(公告)号：EP2839779A4
公开(公告)日：2015-04-15
申请号：EP13778140
申请日：2013-04-18
申请人： TS TECH CO LTD , JOSHO GAKUEN EDUCATIONAL FOUNDATION , UNIV NIHON
发明人： SUGIYAMA SHINJI , NAKANO TOYOKAZU , OHSUGA MIEKO , KOBAYASHI HIROYUKI , YASUDA SHOTA , KAGEYAMA ICHIRO , KURIYAGAWA YUKIYO
IPC分类号： A61B5/0408 , A61B5/0428 , A61B5/0452 , A61B5/0478 , B60N2/90 , B60R21/015
CPC分类号： A61B5/18 , A61B5/0245 , A61B5/0402 , A61B5/0428 , A61B5/0456 , A61B5/6891 , A61B5/6893 , A61B5/7278 , B60N2/002 , B60N2/64

10. 发明公开

EP4300185A1 215-222 NM WAVELENGTH LASER BEAM GENERATING APPARATUS 审中-实审
公开(公告)号：EP4300185A1
公开(公告)日：2024-01-03
申请号：EP22759711.9
申请日：2022-02-24
申请人： Josho Gakuen Educational Foundation , TOSOH SGM CORPORATION
发明人： KAMIMURA, Tomosumi , HORIKOSHI, Hideharu , UMEMURA, Nobuhiro
IPC分类号： G02F1/37 , G02F1/39
摘要： The present invention relates to a 215- to 222-nm wavelength laser light generating device comprising: an excitation light source part for converting a laser light with a wavelength of 1030 to 1064 nm to a second harmonic, and generating a laser light with a wavelength of 515 to 532 nm; an optical parametric oscillating part for generating a signal light with a wavelength of 858 to 887 nm and an idler light with a wavelength of 1288 to 1330 nm using the laser light with the wavelength of 515 to 532 nm as an excitation light; a separating part for separating the signal light and the idler light; a first wavelength converting part for generating a fourth harmonic from the signal light; a second wavelength converting part for generating a deep ultraviolet light with a wavelength of 215 to 222 nm by sum frequency with a second harmonic of the excitation light from the idler light; and a coupling part for coupling the fourth harmonic from the first wavelength converting part and the deep ultraviolet light from the second wavelength converting part. The present invention provides a laser generating device that enables to generate simply and efficiently a pulse laser light with a wavelength of 215 to 222 nm including a wavelength of 222 nm disinfecting microorganisms.

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