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1. 发明公开

EP3209198A4 METHOD AND DEVICE FOR COMPUTING OPTICAL HEMODYNAMIC BLOOD PRESSURE 审中-公开
公开(公告)号：EP3209198A4
公开(公告)日：2017-12-27
申请号：EP17700002
申请日：2017-01-03
申请人： CNOGA MEDICAL LTD
发明人： SEGMAN YOSEF
IPC分类号： A61B5/021 , A61B5/024 , A61B5/0245 , A61B5/026 , G06T7/246 , G06T7/90
CPC分类号： A61B5/0261 , A61B5/01 , A61B5/02125 , A61B5/02416 , A61B5/02427 , A61B5/6826 , A61B8/04 , A61B8/4416 , A61B8/5223
摘要： Device for measuring blood pressure hemodynamically in blood vessels at one or more body locations comprising light source; at least three sensors including an array of at least three optical sensors, for receiving light and for obtaining a signal over time comprising temporal per pixel information for at least two wavelengths of light, and corresponding to a flow of blood within a blood vessel over time; a processing unit configured to receive the signal and generate a continuous dynamic blood pressure reading by using the temporal per pixel information for the at least two wavelengths of light to produce heart rate signals from the blood flow, and by applying a modified Windkessel model on the signal such that the blood pressure also depends on a spatial temporal pressure resistance function over time that depends on a body location of the blood flow over time, the pressure resistance function representing elastance/stiftness.

2. 发明公开

EP3684253A1 BIOPARAMETER DETERMINING DEVICE WITH SPACE-SAVING COMPONENT FOR APPENDAGE 审中-公开
公开(公告)号：EP3684253A1
公开(公告)日：2020-07-29
申请号：EP18855946.2
申请日：2018-08-26
申请人： Cnoga Medical Ltd.
发明人： SEGMAN, Yosef
IPC分类号： A61B5/1455 , A61B5/00

3. 发明公开

EP2872042A4 APPARATUS FOR MEASURING BLOOD CHARACTERISTICS FOR DEPLOYMENT ON A HOST DEVICE HAVING A DIGITAL SENSOR 审中-公开
标题翻译：设备用于测量血液性质使用上的主机设备与数字传感器
公开(公告)号：EP2872042A4
公开(公告)日：2016-03-16
申请号：EP13820443
申请日：2013-07-09
申请人： CNOGA MEDICAL LTD
发明人： SEGMAN YOSEF
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1455
CPC分类号： A61B5/6898 , A61B5/14552 , A61B5/6826 , A61B5/683 , A61B2560/0443
摘要： An apparatus for working in conjunction with a digital sensor, CPU and display of a host device in order to measure blood characteristics that includes a housing configured for association with the host device so as to define between them a chamber into which at least a portion of an appendage of a living being is placed such that a tip of the appendage is deployed adjacent to the digital sensor so as to cover the digital sensor. The chamber substantially encloses the digital sensor. Light from a light source is directed toward the appendage tip, wherein at least some light from the light source is reflected by tissue of the appendage, is received by the sensor and data thereby generated is processed by the CUP to determine the blood characteristics.

4. 发明公开

EP2181650A2 Finger deployed device for measuring blood and physiological characteristics 失效
标题翻译：用手指用于测量血和生理特征的装置
公开(公告)号：EP2181650A2
公开(公告)日：2010-05-05
申请号：EP09174453.2
申请日：2009-10-29
申请人： Cnoga Medical Ltd.
发明人： Segman, Yosef
IPC分类号： A61B5/1455 , A61B5/1495 , A61B5/024
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/02427 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/14552 , A61B5/1495 , A61B5/6826 , A61B5/6838 , A61B2560/0223
摘要： The present invention relates to a device for measuring blood and physiological characteristics by passing light through human tissue that is configured for deployment on a human finger. The device includes a lower finger-trough configured in the main housing of the device; a hingedly attached closeable lid that has an upper finger-trough configured for deployment of at least one finger stabilizing element, the lid being latchable in a closed position; a finger stabilizing element made of a material having flexibly soft malleable characteristics so as to sealingly engage the top of the finger; a light source that is deployed in the sloped end wall of the lower finger-trough adjacent to the lower portion of the finger tip; and an end cap the is deployable on the open end of the device when the lid is in the closed position, which enables calibration of the device with a minimum of light wave "noise" from ambient light.
摘要翻译：本发明涉及一种设备，用于通过光透人体组织并配置成用于对人的手指的部署测量血和生理特征。该装置包括在下手指槽在该装置的主壳体配置; 一个铰链连接闭盖没有被配置用于至少一个手指稳定化元件的部署上手指槽，盖子被在闭合位置可锁定; 由具有弹性可延展的软特性的材料，以密封地接合手指的顶部的手指稳定化元件; 光源也可部署在在下手指槽毗邻手指尖的下部分的倾斜端壁; 和在端盖上的装置的开口端可展开当盖是在关闭位置，这使该装置的校准与来自环境光的最小光波“噪音”的。

5. 发明公开

EP3603509A1 SYSTEM AND METHOD FOR CONTROLLING BLOOD GLUCOSE USING PERSONALIZED HISTOGRAMS 审中-公开
公开(公告)号：EP3603509A1
公开(公告)日：2020-02-05
申请号：EP19188731.4
申请日：2019-07-28
申请人： Cnoga Medical Ltd.
发明人： SEGMAN, Yosef
IPC分类号： A61B5/145
摘要： A method of control of diabetes in a patient, comprising: measuring, using a non-invasive or invasive glucose measuring device, momentary glucose levels of the patient at multiple times a day during an initial time period either continuously or at discrete times, the initial time period being at least a week; recording the momentary glucose levels in a memory in communication with the device, the recording including optional information associated with a recent temporal glucose reading wherein the optional information including one or more of the following information: date, time, time of recent food eating, recent physical activity, diabetes treatment, body temperature, blood pressure, pulse, and drugs associated with the recent temporal glucose reading; constructing, using one or more processors in communication with the device, current curvilinear probability density functions of occurrences of the momentary glucose levels throughout the initial time period and displaying the curvilinear probability density functions on a screen; determining, using one or more processors, a quantitative assessment of at least one of the following current momentary markers during the measurement period from the momentary glucose levels recorded and the optional information: (i) Insulin Resistance (IR), (ii) Glucose Variability (GV), (iii) Glucose Severity Index (GSI) or (iv) Glucose Burden (GB), and constructing, using the one or more processors, a personalized target curvilinear probability density function for the patient based on the current curvilinear probability density functions.

6. 发明公开

EP3582688A1 APPARATUS AND METHOD OF GENERATING PH OF SUBJECT FROM AT LEAST THREE WAVELENGTHS 审中-公开
公开(公告)号：EP3582688A1
公开(公告)日：2019-12-25
申请号：EP18810791.6
申请日：2018-05-24
申请人： Cnoga Medical Ltd.
发明人： SEGMAN, Yosef
IPC分类号： A61B5/145 , G01N21/78 , A61B5/00 , G01N21/80 , A61B5/1455

7. 发明公开

EP2181650A3 Finger deployed device for measuring blood and physiological characteristics 失效
标题翻译：用手指用于测量血和生理特征的装置
公开(公告)号：EP2181650A3
公开(公告)日：2010-07-21
申请号：EP09174453.2
申请日：2009-10-29
申请人： Cnoga Medical Ltd.
发明人： Segman, Yosef
IPC分类号： A61B5/1455 , A61B5/1495 , A61B5/024
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/02427 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/14552 , A61B5/1495 , A61B5/6826 , A61B5/6838 , A61B2560/0223
摘要： The present invention relates to a device for measuring blood and physiological characteristics by passing light through human tissue that is configured for deployment on a human finger. The device includes a lower finger-trough configured in the main housing of the device; a hingedly attached closeable lid that has an upper finger-trough configured for deployment of at least one finger stabilizing element, the lid being latchable in a closed position; a finger stabilizing element made of a material having flexibly soft malleable characteristics so as to sealingly engage the top of the finger; a light source that is deployed in the sloped end wall of the lower finger-trough adjacent to the lower portion of the finger tip; and an end cap the is deployable on the open end of the device when the lid is in the closed position, which enables calibration of the device with a minimum of light wave "noise" from ambient light.

8. 发明公开

EP3659501A1 APPARATUS AND METHOD FOR USING ECG TO RECOVER PULSE WAVEFORM AND OTHER HEMODYNAMICS 审中-公开
公开(公告)号：EP3659501A1
公开(公告)日：2020-06-03
申请号：EP19205767.7
申请日：2019-10-29
申请人： Cnoga Medical Ltd.
发明人： SEGMAN, Yosef , SEGMAN, Yehonatan
IPC分类号： A61B5/0402 , A61B5/00 , A61B5/04
摘要： An apparatus generates a pulse (or other hemodynamic) signal from an ECG signal, and displays a waveform of that signal. An ECG unit comprises electrode(s) for receiving an ECG signal waveform from live tissue and for generating a digital ECG signal; a memory storage; hardware processor(s) configured to constantly apply an integral function to the digital ECG signal and display a waveform of the integral function during a time period. The waveform of the integral function has a shape of a pulse signal waveform of the subject during the time period. The integral function comprises PWF t T = A ∫ t t + T F ECG u du ECG(u) represents an ECG over a specific time period using a specific time resolution. T is determined from the ECG(u) time resolution and pulse frequency, T satisfies the Nyquist sampling theory, t, u are time variables and A is a positive constant. The memory stores the integral function waveform. A weight function PWF t T = A ∫ t t + T F ECG u ⋅ W u − t du may be included.

9. 发明公开

EP3332696A1 APPARATUS FOR ECG-LIKE WAVEFORM 审中-公开
公开(公告)号：EP3332696A1
公开(公告)日：2018-06-13
申请号：EP17191838.6
申请日：2017-09-19
申请人： Cnoga Medical Ltd.
发明人： Segman, Yosef
IPC分类号： A61B5/00
CPC分类号： A61B5/04028 , A61B5/01 , A61B5/02055 , A61B5/02416 , A61B5/0245 , A61B5/0255 , A61B5/04007 , A61B5/044 , A61B5/0456 , A61B5/14551 , A61B5/14552 , A61B5/681 , A61B5/6826 , A61B5/7278 , A61B8/02 , A61B8/5223
摘要： A medical apparatus configured to generate, without multiple electrodes, a signal corresponding to electrical impulses of a heart, and to display a waveform of that signal, comprising: a pulse unit comprising sensor(s) for receiving a single channel pulse signal waveform from a live tissue and for generating a digital pulse signal; a memory buffer; one or more processors configured to constantly apply a derivative function to the digital pulse signal and initiate a display signal to display a waveform of the derivative function during a period of time, wherein the waveform of the derivative function has a shape of an ECG signal waveform of the subject taken during the period of time, wherein the derivative function includes ΔP(t)/Δt, wherein P represents the pulse signal waveform and t is a time variable; and a digital display or printer device configured to display or print the waveform. Multiple channel embodiment also included.

10. 发明授权

EP2181650B1 Finger deployed device for measuring blood and physiological characteristics 失效
标题翻译：用手指用于测量血和生理特征的装置
公开(公告)号：EP2181650B1
公开(公告)日：2012-09-05
申请号：EP09174453.2
申请日：2009-10-29
申请人： Cnoga Medical Ltd.
发明人： Segman, Yosef
IPC分类号： A61B5/021 , A61B5/0205 , A61B5/145 , A61B5/024 , A61B5/1455 , A61B5/1495
CPC分类号： A61B5/0205 , A61B5/021 , A61B5/02427 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/14552 , A61B5/1495 , A61B5/6826 , A61B5/6838 , A61B2560/0223

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