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1. 发明授权

EP3183231B1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENENITRILES 有权
公开(公告)号：EP3183231B1
公开(公告)日：2019-10-09
申请号：EP15834026.5
申请日：2015-08-19
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert H. , SWIERCZEK, Krzysztof , PESAK, Douglas Jay , ANSARI, Hifzur R.
IPC分类号： C07C255/07 , A61Q13/00 , C11B9/00

2. 发明公开

EP3068221A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS 审中-公开
标题翻译：协同配方战斗和节肢动物咬甩
公开(公告)号：EP3068221A1
公开(公告)日：2016-09-21
申请号：EP14861892.9
申请日：2014-11-13
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert H.
IPC分类号： A01N37/10 , A01N35/00
CPC分类号： A01N37/18 , A01N31/02 , A01N31/06 , A01N35/02 , A01N37/30 , A01N37/36 , A01N37/40 , A01N37/42 , A01N43/08 , A01N43/16 , A01N49/00 , A01N37/10
摘要： Control or repellency of biting arthropods, particularly biting insects, is accomplished by bringing the biting arthropods into contact with combinations of compounds identical or related to those found on human/animal skin or in plants acting synergistically with one another, or in combination with conventional repellents like DEET®, para-menthane-3,8-diol (PMD),
sec -butyl-2-(2-hydroxyethyl) piperidine carboxylate ("Picaridin"), or other nitrogen containing repellents selected from amines, amides and nitrogen containing heterocyclic compounds, or any synergistic combination of DEET®, PMD, Picaridin, or other nitrogen containing repellents selected from amines, amides and nitrogen containing heterocyclic compounds.
摘要翻译：控制或咬节肢动物，尤其叮咬昆虫的驱避性通过使咬节肢动物接触到相同的或相关的那些对人/动物的皮肤或与彼此协同作用植物中发现的化合物的组合，或与常规驱虫剂组合来实现 DEET®等，对 - 薄荷烷-3,8-二醇（PMD），仲 - 丁基-2-（2-羟乙基）哌啶羧酸酯（“picaridin”），或其它含氮的驱虫剂从胺，酰胺和杂环氮含选择化合物，或从cardamines，酰胺和含氮杂环化合物中选择DEET®，PMD，Picaridin，或其它含氮驱避剂的任何协同组合。

3. 发明公开

EP2875141A1 ANTIMICROBIAL AGENTS 审中-公开
标题翻译：抗微生物剂
公开(公告)号：EP2875141A1
公开(公告)日：2015-05-27
申请号：EP13820439.1
申请日：2013-04-30
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert, H.
IPC分类号： C12P7/26
CPC分类号： A01N35/06 , A01N31/06 , A01N37/02 , A23G4/06 , A23L3/34 , A23V2002/00 , C07C35/18 , C07C49/603
摘要： Compounds are used in compositions as antimicrobial agents against microbes, such as for example, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and Aspergillus brasiliensis. Antimicrobial action is obtained by contact of a microorganism with at least one of the compounds of the structure (I); wherein R is a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero or one double bond and a total of from 1 to 11 carbon atoms; R
1 is -OH, =0 or -OC(0)CH
3 and wherein the compounds of structure (I) contain a total of from 9 to 18 carbon atoms in the compounds.
摘要翻译：化合物在组合物中用作针对微生物的抗微生物剂，例如金黄色葡萄球菌，表皮葡萄球菌，大肠杆菌，铜绿假单胞菌，白色念珠菌和巴西曲霉（Aspergillus brasiliensis）。通过微生物与结构（I）的至少一种化合物接触获得抗微生物作用; 其中R是具有0或1个双键并且总共具有1至11个碳原子的支链或直链饱和或不饱和烃基; R 1是-OH，= O或-OC（O）CH 3，并且其中结构式（I）的化合物在化合物中总共含有9-18个碳原子。

4. 发明公开

EP2849564A1 CONTROL AND REPELLENCY OF MOSQUITOES 有权
标题翻译：战斗和蚊子威慑
公开(公告)号：EP2849564A1
公开(公告)日：2015-03-25
申请号：EP13784978.2
申请日：2013-04-30
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert, H.
IPC分类号： A01N37/10 , A01N35/00
CPC分类号： A01N49/00 , A01N31/06 , A01N35/06 , A01N37/02 , A01N37/18 , A01N37/36 , A01N37/42 , A01N43/08 , A01N43/16 , A01N2300/00 , A01N37/10
摘要： Control or repellency of mosquitoes is accomplished by bringing the insects into contact with at least one of the compounds of the structure (I): Formula (I) wherein R is selected from -OH, =O, -OC(O)R
4 , -OR
6 , -(OR)
2 , wherein each R
6 is independently selected from an alkyl group containing from 1 to 4 carbon atoms and R
4 is a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH
2 , with the proviso that when X is O R can only be =O; each Z is independently selected from (CH) and (CH
2 ); y is a numeral selected from 1 and 2; R
1 is selected from H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; R
2 is selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms; R
3 is selected from the group consisting of H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, -(CH
2 )
n OH, -C(O)OR
5 , -CH
2 C(O)OR
7 , -CH
2 C(O)R
8 , -C(O)NR
9 R
10 , -CH
2 C(O)NR
11 R
12 where each of R
5 , R
7 , R
8 , R
9 ,R
10 , R
11 and R
12 is independently selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms and n is an integer of from 1 to 12; the bond between the 2 and 3 positions in the ring structure may be a single or a double bond; and wherein the compounds of structure (I) contain from 11 to 20 total carbon atoms in the compounds, with the proviso that when R is =0, X is CH
2 , Z is CH
2 , y is 1 R
2 is H, and R
3 is CH
2 C(0)OR
7 then the total number of carbon atoms in the compounds of structure (I) is from 15 to 20 carbon atoms, and when X is O and R is =O the total number of carbon atoms in the compounds of structure (I) is from 11 to 17 carbon atoms. The invention also includes optical isomers, diastereomers and enantiomers of the named structures. Thus, at all stereocenters where stereochemistry is not explicitly defined, all possible epimers are envisioned.

5. 发明公开

EP2844066A1 KILLING OF BED BUGS 审中-公开
标题翻译：杀死臭虫
公开(公告)号：EP2844066A1
公开(公告)日：2015-03-11
申请号：EP13785292.7
申请日：2013-04-30
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert, H.
IPC分类号： A01N35/06
CPC分类号： C07C69/533 , A01N31/06 , A01N35/02 , A01N35/06 , A01N37/02 , C07C35/18 , C07C49/543
摘要： Killing of bed bugs is accomplished by bringing the bed bugs into contact with a toxic amount of one of the compounds of the structure (I) wherein X is -OH, =O, or -O(O)CR, wherein R is selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyi group with zero to three double bonds and from 1 to 1 1 carbon atoms; R
1 , is H or CH
3 ; R
2 is H or CH
3 ; R
3 is H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 11 carbon atoms; and wherein the compounds of structure (I) contain from 6 to 20 total carbon atoms in the compounds.
摘要翻译：通过使臭虫与有毒量的其中X是-OH，= O或-O（O）CR的结构（I）的化合物中的一种接触来完成对臭虫的杀死，其中R选自 H和具有0至3个双键和1至11个碳原子的支链或直链饱和或不饱和烃基; R 1是H或CH 3; R 2是H或CH 3; R 3是H或具有0-3个双键和1-11个碳原子的支链或直链饱和或不饱和烃基; 并且其中结构（I）的化合物在化合物中含有总共6至20个碳原子。

6. 发明授权

EP2365950B1 PRODUCTION OF PHEROMONES AND FRAGRANCES FROM SUBSTITUTED AND UNSUBSTITUTED 1-ALKEN-3-YL ALKYLATES 有权
标题翻译：取代和未取代1-ALKEN -3- YLALKYLATEN的制造和香料信息素
公开(公告)号：EP2365950B1
公开(公告)日：2014-10-29
申请号：EP09823934.6
申请日：2009-10-29
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert, H. , PASSARO, Linda, C.
IPC分类号： C07C1/00 , C07C1/32 , C07D309/00 , C07D317/12 , C07C45/51 , C07C47/21 , C07C67/08 , C07C45/59 , C07C67/293 , C07C41/50 , C07C43/303
CPC分类号： C07C45/59 , C07C41/50 , C07C45/515 , C07C67/08 , C07C67/293 , C07D317/12 , C07C47/21 , C07C69/007 , C07C69/145 , C07C43/303

7. 发明公开

EP3954210A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS 审中-实审
公开(公告)号：EP3954210A1
公开(公告)日：2022-02-16
申请号：EP21190779.5
申请日：2021-08-11
申请人： Bedoukian Research, Inc.
发明人： Bedoukian, Robert H.
IPC分类号： A01N31/06 , A01N37/18 , A01N37/36 , A01N37/42 , A01N37/46 , A01N43/08 , A01N43/18 , A01N47/16 , A01P17/00
摘要： Control or repellency of biting arthropods, particularly biting insects, is accomplished by bringing the biting arthropods into contact with combinations of compounds identical or related to those found on human/animal skin or in plants acting synergistically with one another, or in combination with conventional repellents like N,N-diethyl-3-methylbenzamide (DEET ® ), para-menthane-3,8-diol (PMD), sec-butyl-2-(2-hydroxyethyl) piperidine carboxylate ("Picaridin"), or other nitrogen containing repellents selected from amines, amides and nitrogen containing heterocyclic compounds, or any synergistic combination of DEET ® , PMD, Picaridin, or other nitrogen containing repellents selected from amines, amides and nitrogen containing heterocyclic compounds.

8. 发明公开

EP3183330A1 PERFUME COMPOSITIONS CONTAINING ISOMERIC ALKADIENALS 有权
标题翻译：含有异构醇的香料组合物
公开(公告)号：EP3183330A1
公开(公告)日：2017-06-28
申请号：EP15834554.6
申请日：2015-08-19
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert H. , SWIERCZEK, Krzysztof , PESAK, Douglas Jay , ANSARI, Hifzur R.
IPC分类号： C11D3/50
CPC分类号： C07C47/21 , C11B9/0015
摘要： A perfume composition comprising an effective amount of at least one alkadienal selected from 4,8-undecadienal and isomers thereof, 4,9-dodecadienal and isomers thereof, and 4,10-tridecadienal and isomers thereof. The isomers of 4,8-undecadienal comprise Z,Z-4,8-undecadienal, E,E-4,8-undecadienal, and mixed Z/E isomers of 4,8-undecadienal; the isomers of 4,9-dodecadienal comprise Z,Z-4,9-dodecadienal, E,E-4,9-dodecadienal, and mixed Z/E isomers of 4,9-dodecadienal; and the isomers of 4,10-tridecadienal comprise Z,Z-4,10-tridecadienal, E,E-4,10-tridecadienal, and mixed Z/E isomers of 4,10-tridecadienal. A composition comprising an effective amount of at least one alkadienal selected from 4,8-undecadienal and isomers thereof, 4,9-dodecadienal and isomers thereof, and 4,10-tridecadienal and isomers thereof. Processes for the preparation of the isomer mixtures of alkadienals are provided. The isomeric alkadienals have a range of fresh, watery, ozone, grapefruit, tangerine, orange peel, aldehydic notes of exceptional strength.
摘要翻译：包含有效量的至少一种选自4,8-十一碳二烯醛及其异构体，4,9-十二碳二烯醛及其异构体，和4,10-十三碳二烯醛及其异构体的链二烯醛的香料组合物。 4,8-十一碳二烯醛的异构体包括Z，Z-4,8-十一碳二烯醛，E，E-4,8-十一碳二烯醛和4,8-十一碳二烯醛的混合Z / E异构体; 4,9-十二碳二烯醛的异构体包含Z，Z-4,9-十二碳二烯醛，E，E-4,9-十二碳二烯醛和4,9-十二碳二烯醛的混合Z / E异构体; 并且4,10-十三碳二烯醛的异构体包含4,10-十三碳二烯醛的Z，Z-4,10-十三碳二烯醛，E，E-4,10-十三碳二烯醛和混合的Z / E异构体。包含有效量的至少一种选自4,8-十一碳二烯醛及其异构体，4,9-十二碳二烯醛及其异构体和4,10-十三碳二烯醛及其异构体的链二烯醛的组合物。提供了制备链烷二烯异构体混合物的方法。异构的alkadienals有一系列新鲜，含水，臭氧，葡萄柚，橘子，橙皮，具有非凡强度的醛类香味。

9. 发明公开

EP3183231A1 PERFUME COMPOSITONS CONTAINING ISOMERIC ALKADIENENITRILES 有权
标题翻译：含有异构化阿卡地尼的香料复合物
公开(公告)号：EP3183231A1
公开(公告)日：2017-06-28
申请号：EP15834026.5
申请日：2015-08-19
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert H. , SWIERCZEK, Krzysztof , PESAK, Douglas Jay , ANSARI, Hifzur R.
IPC分类号： C07C255/07 , A61Q13/00 , C11B9/00
CPC分类号： C07C253/30 , C07B2200/09 , C07C255/07 , C11B9/0023
摘要： A perfume composition comprising an effective amount of at least one alkadienenitrile selected from 4,8-undecadienenitrile and isomers thereof, 4,9-dodecadienenitrile and isomers thereof, and 4,10-tridecadienenitrile and isomers thereof. The isomers of 4,8-undecadienenitrile comprise Z,Z-4,8-undecadienenitrile, E,E-4,8-undecadienenitrile, and mixed Z/E isomers of 4,8-undecadienenitrile; the isomers of 4,9-dodecadienenitrile comprise Z,Z-4,9-dodecadienenitrile, E,E-4,9-dodecadienenitrile, and mixed Z/E isomers of 4,9-dodecadienenitrile; and the isomers of 4,10-tridecadienenitrile comprise Z,Z-4,10-tridecadienenitrile, E,E-4,10-tridecadienenitrile, and mixed Z/E isomers of 4,10-tridecadienenitrile. A composition comprising an effective amount of at least one alkadienenitrile selected from 4,8-undecadienenitrile and isomers thereof, 4,9-dodecadienenitrile and isomers thereof, and 4,10-tridecadienenitrile and isomers thereof. Processes for the preparation of the isomeric alkadienenitriles are provided. The isomeric alkadienenitriles have a range of fresh, citric, ozonic and floral notes of exceptional strength.
摘要翻译：一种香料组合物，其中含有有效量的至少一种选自4,8-十一碳二烯腈及其异构体，4,9-十二碳烯二腈及其异构体和4,10-十三碳二烯腈及其异构体的亚氨二腈。 4,8-十一碳烯腈的异构体包括Z，Z-4,8-十一碳烯腈，E，E-4,8-十一碳烯腈和4,8-十一碳二烯腈的混合Z / E异构体; 4,9-十二碳烯腈的异构体包括Z，Z-4,9-十二碳烯二腈，E，E-4,9-十二碳烯二腈和4,9-十二碳烯腈的混合Z / E异构体; 并且4,10-十三碳烯腈的异构体包括Z，Z-4,10-十三碳烯腈，E，E-4,10-十三碳烯二腈和4,10-十三碳烯腈的混合Z / E异构体。包含有效量的至少一种选自4,8-十一碳二烯腈及其异构体，4,9-十二碳烯二腈及其异构体和4,10-十三碳二烯腈及其异构体的链二烯腈的组合物。提供了制备异构体链二烯腈的方法。异构体烯二腈具有一系列具有优异强度的新鲜柠檬酸，臭氧和花香香料。

10. 发明公开

EP2925126A1 FEEDING DETERRENCE IN AGRICULTURAL PESTS SUCH AS HEMIPTERA, LEPIDOPTERA AND COLEOPTERA 审中-公开
标题翻译：农业害虫如何SCHNABELKERFEN，蝴蝶，甲虫植物攻击威慑
公开(公告)号：EP2925126A1
公开(公告)日：2015-10-07
申请号：EP13784833.9
申请日：2013-04-30
申请人： Bedoukian Research, Inc.
发明人： BEDOUKIAN, Robert, H.
IPC分类号： A01N37/10
CPC分类号： A01N43/16 , A01N31/06 , A01N35/06 , A01N37/02 , A01N37/06 , A01N37/18 , A01N37/36 , A01N37/42 , A01N43/08 , A01N49/00
摘要： Compounds are used as agents that deter feeding of crops by agricultural pests such as hemiptera, lepidoptera and coleoptera, including, but not limited to, stink bugs, codling moth larvae and granary weevils. Feeding deterrence is obtained by contact of the insects with at least one of the compounds of the structure (I) wherein R is -OH, =O, -OC(O)R
4 , -OR
6 , or -(OR
6 )
2 , wherein each R
6 , is independently an alkyl group containing from 1 to 4 carbon atoms and R
4 is a branched or straight chain, saturated or unsaturated, hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH
2 with the proviso that when X is O R can only be =O; each Z is independently (CH) or (CH
2 ); y is a numeral selected from 1 and 2; R
1 is H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; R
2 is H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms; R
3 is selected from H, a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms, -(CH2)
n OH, -C(O)OR
5 , -CH
2 C(O)OR
7 , - CH
2 C(O)R
8 , -C(O)NR
9 R
10 , and -CH
2 C(O)NR
11 R
12 where each of R
5 , R
7 , R
8 , R
9 , R
10 , R
11 and R
12 is independently selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms and n is an integer of from 1 to 12; the bond between the 2 and 3 positions in the ring structure may be a single or a double bond; and wherein the compounds of structure (I) contain from 9 to 20 total carbon atoms in the compounds.

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