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1. 发明授权

EP2957638B1 PESTICIDAL PROTEINS AND METHODS FOR THEIR USE 有权
公开(公告)号：EP2957638B1
公开(公告)日：2018-12-12
申请号：EP15176499.0
申请日：2010-02-26
申请人： Athenix Corporation
发明人： SAMPSON, Kimberley, S. , TOMSO, Daniel, J. , DUMITRU, Razvan, Valeriu
IPC分类号： C12N15/82 , C07K14/325 , A01N63/02
CPC分类号： C12N15/8286 , A01N63/02 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated toxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:50-96, or the nucleotide sequence set forth in SEQ ID NO:1-47, as well as variants and fragments thereof.

2. 发明授权

EP2198030B1 SYNTHETIC GENES ENCODING CRY1AC 有权
标题翻译：对于合成基因编码的Cry1Ac
公开(公告)号：EP2198030B1
公开(公告)日：2016-09-14
申请号：EP08837113.3
申请日：2008-10-10
申请人： Athenix Corporation
发明人： CAROZZI, Nadine , DESAI, Nalini , TOMSO, Daniel, J.
IPC分类号： C07K14/325 , C12N15/82
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions containing a synthetic nucleotide sequence encoding a Cry1 Ac protein are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided, wherein the nucleotide sequences are set forth in SEQ ID NO: 5, 1, 2, 3, or 4, as well as variants and fragments thereof.

3. 发明公开

EP2728006A2 Synthetic genes encoding CRY1AC 有权
标题翻译：编码的Cry1Ac合成基因
公开(公告)号：EP2728006A2
公开(公告)日：2014-05-07
申请号：EP13183867.4
申请日：2008-10-10
申请人： Athenix Corporation
发明人： Carozzi, Nadine , Desai, Nalini , Tomso, Daniel J.
IPC分类号： C12N15/82
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions containing a synthetic nucleotide sequence encoding a Cry1 Ac protein are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided, wherein the nucleotide sequences are set forth in SEQ ID NO: 5, 1, 2, 3, or 4, as well as variants and fragments thereof.

4. 发明公开

EP2671951A2 Pesticidal genes from Brevibacillus and methods for their use 审中-公开
标题翻译： Pestizidgene aus Brevibacillus und Verfahren zu deren Verwendung
公开(公告)号：EP2671951A2
公开(公告)日：2013-12-11
申请号：EP13182993.9
申请日：2009-12-22
申请人： Athenix Corporation
发明人： Sampson, Kimberly S. , Tomso, Daniel J. , Guo, Rong
IPC分类号： C12N15/82 , C07K14/195 , A01H5/00
CPC分类号： C12N15/8286 , C07K14/195 , C07K14/325 , C07K14/345 , Y02A40/162
摘要： Compositions and methods for conferring insecticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions including a coding sequence for a Brevibacillus-derived delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules having nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 4, 7, or 10, or the nucleotide sequence set forth in SEQ ID NO:9, 1, 3, 5, 6, 8, 11, 12, 13, 14, or 15, as well as variants and fragments thereof.
摘要翻译：提供了赋予细菌，植物，植物细胞，组织和种子的杀虫活性的组合物和方法。提供了包含短杆菌属来源的δ-内毒素多肽的编码序列的组合物。编码序列可用于DNA构建体或表达盒中，用于在植物和细菌中转化和表达。组合物还包括转化的细菌，植物，植物细胞，组织和种子。特别地，提供了分离的δ-内毒素核酸分子。另外，包括对应于多核苷酸的氨基酸序列，以及与这些氨基酸序列特异性结合的抗体。特别地，本发明提供了具有编码SEQ ID NO：2,4,7或10所示氨基酸序列的核苷酸序列的分离的核酸分子，或者SEQ ID NO：9， 3，5，6，8，11，12，13，14或15，以及其变体和片段。

5. 发明公开

EP2455391A3 A family of pesticidal proteins and methods for their use 审中-公开
标题翻译：蛋白质和使用方法的农药家庭
公开(公告)号：EP2455391A3
公开(公告)日：2012-08-22
申请号：EP11173099.0
申请日：2007-06-15
申请人： Athenix Corporation
发明人： Koziel, Michael, G , Desai, Nalini , Deter, Rebekah , Tomso, Daniel, John , Hargiss, Tracy , Duck, Nicholas, B. , Carozzi, Nadine , Guo, Rong
IPC分类号： C07K14/195 , C07K14/32 , C12N15/82
CPC分类号： C12N15/8286 , A01N37/44 , C07K14/325 , C12P21/02 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 2, 61, 4, 6, 7, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, 35, or 37, the nucleotide sequence set forth in SEQ ID NO: 1, 60, 3, 5, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, or 36, or the nucleotide sequence deposited in a bacterial host as Accession No. NRRL B-30961, B-30955, B-30956, B-30957, B-30958, B-30942, B-30939, B-30941, B-50047, B-50047, B-30959, B-30960, B-30943, B-50048, or B-50048, as well as variants and fragments thereof.

6. 发明公开

EP2455394A2 A family of pesticidal proteins and methods for their use 有权
公开(公告)号：EP2455394A2
公开(公告)日：2012-05-23
申请号：EP11173106.3
申请日：2007-06-15
申请人： Athenix Corporation
发明人： Koziel, Michael, G , Desai, Nalini , Deter, Rebekah , Tomso, Daniel, John , Hargiss, Tracy , Duck, Nicholas, B. , Carozzi, Nadine , Guo, Rong
IPC分类号： C07K14/195 , C07K14/32 , C12N15/82
CPC分类号： C12N15/8286 , A01N37/44 , C07K14/325 , C12P21/02 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 13, 2, 4, 6, 7, 9, 11, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, 35, 37 or 61, the nucleotide sequence set forth in SEQ ID NO: 12, 1, 3, 5, 8, 10, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, or 60, or the nucleotide sequence deposited in a bacterial host as Accession No. NRRL B-30961, B-30955, B-30956, B-30957, B-30958, B-30942, B-30939, B-30941, B-50047, B-30959, B-30960, B-30943, or B-50048, as well as variants and fragments thereof.

7. 发明公开

EP2449109A1 AXMI-205 PESTICIDAL GENE AND METHODS FOR ITS USE 有权转让
标题翻译： AXMI-205 PESTIZIDGEN及其使用方法
公开(公告)号：EP2449109A1
公开(公告)日：2012-05-09
申请号：EP10732575.5
申请日：2010-07-01
申请人： Athenix Corporation
发明人： DESAI, Nalini , HINSON, Jill , BALUSUBRAMANIAN, Deepa , SAMPSON, Kimberly, S. , TOMSO, Daniel, J. , LEHTINEN, Duane, Alan , DUCK, Nicholas, B.
IPC分类号： C12N15/82
CPC分类号： C07K14/195 , C07K14/22 , C07K16/1203 , C12N15/8285 , C12N15/8286 , C12Q1/6876 , Y02A40/162 , Y02A40/164
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated pesticidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 3, or 4, the nucleotide sequence set forth in SEQ ID NO:1, 9, 10, or 11, as well as variants and fragments thereof.

8. 发明公开

EP2327785A3 EPSP synthase domains conferring glyphosate resistance 审中-公开
标题翻译： EPSPSynthasedomänen草甘膦抗性
公开(公告)号：EP2327785A3
公开(公告)日：2011-08-24
申请号：EP11158889.3
申请日：2007-01-11
申请人： Athenix Corporation
发明人： Carr, Brian , Hammer, Philip E. , Hinson, Todd K. , Vande Berg, Brian
IPC分类号： C12N15/82 , C12N15/54 , C12N9/10 , A01H5/10
CPC分类号： C12N15/8275 , C12N9/1092
摘要： Compositions and methods for conferring tolerance to glyphosate in bacteria, plants, planet cells, tissues and seeds are provided. Compositions include novel EPSP synthase enzymes and nucleic acid molecules encoding such enzymes, vectors comprising those nucleic acid molecules, and host cells comprising the vectors. The novel proteins comprise at least one sequence domain selected from the domains provided herein. These sequence domains can be used to identify EPSP synthases with glyphosate resistance activity.

9. 发明授权

EP1947184B1 Delta-endotoxin genes and methods for their use 有权
标题翻译： δ-内毒素及其使用的基因和方法
公开(公告)号：EP1947184B1
公开(公告)日：2011-03-30
申请号：EP08005377.0
申请日：2004-02-20
申请人： Athenix Corporation
发明人： Carozzi, Nadine , Hargiss, Tracy , Koziel, Michael G. , Duck, Nicholas B. , Carr, Brian
IPC分类号： C12N15/32 , C12N15/82 , C12N5/14 , C12N15/63 , A01H1/00 , C07K14/325 , C07K16/12 , A01N63/00
CPC分类号： C12N15/8286 , C07K14/325 , Y02A40/162
摘要： Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin and delta-endotoxin-associated polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated delta-endotoxin and delta-endotoxin-associated nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequences shown in SEQ ID NOS: 3, 5, 7, 9, 11, 14, 16, 18, 20, 22, 24, 27, and 29, and the nucleotide sequences set forth in SEQ ID NOS: 1, 2, 4, 6, 8, 10, 12, 13, 15, 17, 19, 21, 23, 25, 26, and 28, as well as variants and fragments thereof.

10. 发明公开

EP2297190A2 AXMI-115, AXMI-113, AXMI-005, AXMI-163 AND AXMI-184: VIP3A INSECTICIDAL PROTEINS FROM BACILLUS THURINGIENSIS AND METHODS FOR THEIR USE 审中-公开
标题翻译： AXMI-115，AXMI-113，AXMI-005，AXMI-163和AXMI-184：从苏云金芽孢杆菌的杀虫VIP3A蛋白和它们的使用方法
公开(公告)号：EP2297190A2
公开(公告)日：2011-03-23
申请号：EP09774514.5
申请日：2009-07-02
申请人： Athenix Corporation
发明人： SAMPSON, Kimberly, S. , AGARWAL, Shruti , CAMPBELL, Chris , MCNULTY, Brian , TOMSO, Daniel, J. , CAROZZI, Nadine , HARGISS, Tracy , KOZIEL, Michael, G. , DUCK, Nicholas, B. , HEINRICHS, Volker
IPC分类号： C07K14/325 , C12N15/82
CPC分类号： C12N15/8286 , A01N37/18 , C07K14/32 , C07K14/325 , C07K16/1278 , Y02A40/162
摘要： Compositions and methods for conferring insecticidal activity to host cells are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in host cells. Compositions also comprise transformed host cells. In particular, isolated delta-endotoxin nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed, and antibodies specifically binding to those amino acid sequences. In particular, the present invention provides for isolated nucleic acid molecules comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:4, 5, 6, 13, or 14, or the nucleotide sequence set forth in SEQ ID NO:1, 2, 3, 11, or 12, as well as variants and fragments thereof.

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