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1. 发明授权

EP1025427B1 Blood tubing set integrity test for extracorporeal circuits 有权
标题翻译：血液软管的完整性测试设置体外循环线电路
公开(公告)号：EP1025427B1
公开(公告)日：2007-03-21
申请号：EP98958614.4
申请日：1998-11-17
申请人： Aksys, Ltd.
发明人： KENLEY, Rodney, S. , KAPADIA, Seema, A. , SCHROEDER, Christine, F. , FELDSIEN, Thomas, M. , DUCH, Michael , TREU, Dennis, M. , PETER, Frederick, H., Jr.
IPC分类号： G01M3/28 , A61M1/14
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/1684 , A61M1/3639 , A61M2205/14 , A61M2205/15 , A61M2205/3344 , A61M2205/502
摘要： Several tests are described for verifying the integrity of the extracorporeal circuit of a medical instrument such as a dialysis machine (10). One test verifies the condition of the blood tubing set. Another test verifies that the clamps (AC, VC) in the arterial (42) and venous (40) lines adequately occlude the arterial (42) and venous (40) lines. Another test confirms that the arterial (42) and venous (40) lines are properly installed on their respective ports (104, 102) for receiving the lines after the treatment session has ended. In this last test, a fluid such as heated water in then introduced into one of the arterial (42) or venous (40) lines and sent out of the line through its respective port, where it is detected with suitable fluid detection equipment such as a thermistor (TA, TV). The heated fluid and thermistor verify that the arterial line (42) is connected to its arterial port (102) and the venous line (40) is connected to its venous port (104) and that there is an unobstructed fluid path in the blood tubing set. If the lines are installed on the wrong port, the user is prompted to correctly install the arterial (42) and venous (40) lines on their respective ports.

2. 发明公开

EP1025427A4 BLOOD TUBING SET INTEGRITY TESTS FOR EXTRACORPOREAL CIRCUITS 有权
标题翻译： INTEGRITÄTSPRÜFUNGEINES BLUTLEITUNGENSETSFÜREXTRAKORPORALELEITUNGSKREISLÄUFE
公开(公告)号：EP1025427A4
公开(公告)日：2004-12-08
申请号：EP98958614
申请日：1998-11-17
申请人： AKSYS LTD
发明人： KENLEY RODNEY S , KAPADIA SEEMA A , SCHROEDER CHRISTINE F , FELDSIEN THOMAS M , DUCH MICHAEL , TREU DENNIS M , PETER FREDERICK H JR
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34 , A61M1/36 , G01M3/26 , G01M3/28
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/1684 , A61M1/3639 , A61M2205/14 , A61M2205/15 , A61M2205/3344 , A61M2205/502
摘要： Several tests are described for verifying the integrity of the extracorporeal circuit of a medical instrument such as a dialysis machine (10). One test verifies the condition of the blood tubing set. Another test verifies that the clamps (AC, VC) in the arterial (42) and venous (40) lines adequately occlude the arterial (42) and venous (40) lines. Another test confirms that the arterial (42) and venous (40) lines are properly installed on their respective ports (104, 102) for receiving the lines after the treatment session has ended. In this last test, a fluid such as heated water in then introduced into one of the arterial (42) or venous (40) lines and sent out of the line through its respective port, where it is detected with suitable fluid detection equipment such as a thermistor (TA, TV). The heated fluid and thermistor verify that the arterial line (42) is connected to its arterial port (102) and the venous line (40) is connected to its venous port (104) and that there is an unobstructed fluid path in the blood tubing set. If the lines are installed on the wrong port, the user is prompted to correctly install the arterial (42) and venous (40) lines on their respective ports.
摘要翻译：描述了用于验证诸如透析机的医疗器械的体外电路的完整性的若干测试。一个测试验证血管套管的状况。另一项测试证实，动脉和静脉线中的夹具充分阻塞动脉和静脉线。另一项测试证实，在治疗结束后，动脉和静脉线适当地安装在各自的端口上用于接收线。在最后一次测试中，然后将诸如加热水的流体引入动脉或静脉血管中的一个，并通过其相应的端口从管线中输出，在那里用合适的流体检测设备如热敏电阻检测。加热的流体和热敏电阻验证动脉管线是否连接到其动脉端口，静脉管线连接到其静脉端口，并且在血管组中存在无阻碍的流体路径。如果线路安装在错误的端口上，则会提示用户在相应的端口上正确安装动脉和静脉线。

3. 发明公开

EP0846470A1 Batch dialysate conductivity adjustment in a batch dialysate preparation system 失效
标题翻译：在批式透析液制备系统中批量透析液电导率调节
公开(公告)号：EP0846470A1
公开(公告)日：1998-06-10
申请号：EP97121592.6
申请日：1997-12-08
申请人： Aksys, Ltd.
发明人： Shah, Dilip H. , Feldsein, Thomas M.
IPC分类号： A61M1/16
CPC分类号： A61L2/04 , A61L2/18 , A61M1/16 , A61M1/1601 , A61M1/1607 , A61M1/1609 , A61M1/1649 , A61M1/165 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/1662 , A61M1/1666 , A61M1/1668 , A61M1/1672 , A61M1/1682 , A61M1/1684 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M1/1692 , A61M1/1694 , A61M1/28 , A61M1/3434 , A61M1/3437 , A61M1/3462 , A61M1/3465 , A61M1/3626 , A61M1/3627 , A61M1/3629 , A61M1/3639 , A61M1/3641 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3647 , A61M1/3649 , A61M1/365 , A61M39/16 , A61M2205/12 , A61M2205/15 , A61M2205/17 , A61M2205/3317 , A61M2205/3324 , A61M2205/3382 , A61M2205/3386 , A61M2205/505 , A61M2205/6072 , A61M2205/705 , A61M2205/707 , A61M2205/7554 , A61M2205/7581 , A61M2206/11 , B01D61/02 , B01D61/025 , B01D61/04 , B01D61/12 , B01D65/022 , B01D65/102 , B01D2311/04 , B01D2321/08 , C02F1/441 , F16K17/0453 , B01D2311/10
摘要： A method of adjusting the final conductivity of a batch of dialysate to bring the conductivity down to a desired level is described. The batch of dialysate is prepared by mixing excess quantities (e.g., 5%) of dialysate solution chemicals with water to form a solution with a conductivity greater than that required for the particular batch. A measurement of the dialysate solution is taken. A precise volume of water is added to the dialysate solution to dilute the dialysate to the proper level. The precise volume of water is calculated from a known or estimated total system, the desired conductivity level and the actual conductivity. The resulting diluted dialysate is at the desired conductivity level. Excess dialysate which may be present in the dialysate circuit or associated tanks is then flushed to a drain. In a hemodialysis embodiment, the excess dialysate may be flushed through the dialyzer into the blood lines to rinse any pyrogens from the extracorporeal circuit.
摘要翻译：描述了调节一批透析液的最终电导率以使电导率降低到期望水平的方法。通过将过量（例如5％）的透析液溶液化学品与水混合以形成导电率大于特定批次所需的溶液的溶液来制备透析液批次。进行透析液溶液的测量。将精确体积的水加入透析液中以稀释透析液至适当的水平。从已知或估计的总系统，期望的电导率水平和实际电导率计算精确的水量。所得的稀释透析液处于所需的电导率水平。然后可能存在于透析液回路或相关联的容器中的过量透析液被冲洗至排水管。在血液透析实施方案中，可将过量透析液通过透析器冲洗到血液管线中以冲洗来自体外回路的任何热原。

4. 发明授权

EP0959980B1 DIALYSIS MACHINES WITH TOUCH SCREEN USER INTERFACE 失效
标题翻译：带触摸感应屏幕作为用户界面透析机
公开(公告)号：EP0959980B1
公开(公告)日：2005-06-29
申请号：EP97938177.9
申请日：1997-08-12
申请人： Aksys, Ltd.
发明人： KENLEY, Rodney, S. , MATTHEWS, Dawn , WILKERSON, Douglas, L. , DEJESUS, Joel , BROSE, Tom, L. , GEBHARDT, Andrew , PLUMMER, Lori, A. , PETER, Frederick, H., Jr. , SAGE, Russell, L. , TREU, Dennis, M. , WIKLUND, Michael, Edward , DOLAN, William, R. , BARRETT, Shawn, O.
IPC分类号： A61M1/16
CPC分类号： A61M1/14 , A61M2205/17 , A61M2205/502 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06F19/3481 , G16H40/63 , Y10S248/919
摘要： A user interface for a medical instrument such as a dialysis machine is described which uses both a touch screen and at least one hard key off of the touch screen to effectuate a change in a parameter associated with the operation of the machine or the treatment session. The user interface is connected to a central computer control system having a host microprocessor and a backup safety microprocessor. The hard key is directly wired to the safety microprocessor. After the user selects a new parametric value on the touch screen, the user presses a hard key. The host and safety microprocessors implement a verification routine to insure that the entered parameter is appropriate for the patient's treatment and the display on the touch screen. If the verification procedure ends in a positive result, the user is prompted to presses a second hard key to confirm the change, causing an additional verification check to be preformed. If the additional verification check is successful, the parametric value is entered into a memory (such as a hard disk) storing instructions for operation of the medical instrument.

6. 发明公开

EP1140251A1 AN APPARATUS FOR PREPARING A FLUID FOR A MEDICAL PROCEDURE 有权
标题翻译：开瓶器用于打开药物容器的膜
公开(公告)号：EP1140251A1
公开(公告)日：2001-10-10
申请号：EP99959932.7
申请日：1999-12-21
申请人： TEIJIN LIMITED , Aksys, Ltd.
发明人： MORIYAMA, Naohiko , YANO, Tetsuya,Teijin Ltd., , IMAI, Ken,Teijin Ltd , DEGUCHI, Tsuneo,Teijin Ltd
IPC分类号： A61M1/16
CPC分类号： A61M1/1656 , A61M1/1666 , A61M1/1668 , B67B7/38 , Y10T83/7851 , Y10T83/788 , Y10T83/814 , Y10T83/9382 , Y10T83/9387 , Y10T83/9418 , Y10T137/1759
摘要： The invention provides an apparatus for preparing a fluid for a medical procedure by mixing of at least one medicament in the form of powder with water, the medicament is held in a vessel which defines a bottom, a side wall, and a top opening which is closed by a membrane for sealing the inside of the vessel. The apparatus includes an opener for opening the membrane of the vessel. The opener includes a holder for vertically holding the vessel to downwardly orient the opening; a cutter, provided beneath the opening of the vessel held by the holder, for partially cutting the membrane along the periphery of the opening; a mechanism for vertically moving the holder toward the cutter so that the cutting edge of the cutter pierces to partially separate the membrane from the periphery of the opening whereby the medicament in the vessel falls from the vessel; a receiving member, in the form of a mesh provided beneath the cutter, for receiving all of the medicament from the vessel; and a nozzle for directing water from the source of water in the form of a spray to the medicament received by the receiving member to dissolve the medicament into the water directed to the medicament.

7. 发明公开

EP1025427A1 BLOOD TUBING SET INTEGRITY TESTS FOR EXTRACORPOREAL CIRCUITS 有权
标题翻译： Integritätsprüfungeines BlutleitungensetsfürextrakorporaleLeitungskreisläufe
公开(公告)号：EP1025427A1
公开(公告)日：2000-08-09
申请号：EP98958614.4
申请日：1998-11-17
申请人： Aksys, Ltd.
发明人： KENLEY, Rodney, S. , KAPADIA, Seema, A. , SCHROEDER, Christine, F. , FELDSIEN, Thomas, M. , DUCH, Michael , TREU, Dennis, M. , PETER, Frederick, H., Jr.
IPC分类号： G01M3/28 , A61M1/14
CPC分类号： A61M1/3621 , A61M1/16 , A61M1/1684 , A61M1/3639 , A61M2205/14 , A61M2205/15 , A61M2205/3344 , A61M2205/502
摘要： Several tests are described for verifying the integrity of the extracorporeal circuit of a medical instrument such as a dialysis machine (10). One test verifies the condition of the blood tubing set. Another test verifies that the clamps (AC, VC) in the arterial (42) and venous (40) lines adequately occlude the arterial (42) and venous (40) lines. Another test confirms that the arterial (42) and venous (40) lines are properly installed on their respective ports (104, 102) for receiving the lines after the treatment session has ended. In this last test, a fluid such as heated water in then introduced into one of the arterial (42) or venous (40) lines and sent out of the line through its respective port, where it is detected with suitable fluid detection equipment such as a thermistor (TA, TV). The heated fluid and thermistor verify that the arterial line (42) is connected to its arterial port (102) and the venous line (40) is connected to its venous port (104) and that there is an unobstructed fluid path in the blood tubing set. If the lines are installed on the wrong port, the user is prompted to correctly install the arterial (42) and venous (40) lines on their respective ports.
摘要翻译：描述了用于验证诸如透析机的医疗器械的体外电路的完整性的若干测试。一个测试验证血管套管的状况。另一项测试证实，动脉和静脉线中的夹具充分阻塞动脉和静脉线。另一项测试证实，在治疗结束后，动脉和静脉线适当地安装在各自的端口上用于接收线。在最后一次测试中，然后将诸如加热水的流体引入动脉或静脉血管中的一个，并通过其相应的端口从管线中输出，在那里用合适的流体检测设备如热敏电阻检测。加热的流体和热敏电阻验证动脉管线是否连接到其动脉端口，静脉管线连接到其静脉端口，并且在血管组中存在无阻碍的流体路径。如果线路安装在错误的端口上，则会提示用户在相应的端口上正确安装动脉和静脉线。

8. 发明公开

EP0959980A1 DIALYSIS MACHINES WITH TOUCH SCREEN USER INTERFACE 失效
标题翻译：带触摸感应屏幕作为用户界面透析机
公开(公告)号：EP0959980A1
公开(公告)日：1999-12-01
申请号：EP97938177.0
申请日：1997-08-12
申请人： Aksys, Ltd.
发明人： KENLEY, Rodney, S. , MATTHEWS, Dawn , WILKERSON, Douglas, L. , DEJESUS, Joel , BROSE, Tom, L. , GEBHARDT, Andrew , PLUMMER, Lori, A. , PETER, Frederick, H., Jr. , SAGE, Russell, L. , TREU, Dennis, M. , WIKLUND, Michael, Edward , DOLAN, William, R. , BARRETT, Shawn, O.
IPC分类号： A61M1 , B01D61
CPC分类号： A61M1/14 , A61M2205/17 , A61M2205/502 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06F19/3481 , G16H40/63 , Y10S248/919
摘要： A user interface for a medical instrument such as a dialysis machine is described which uses both a touch screen and at least one hard key off of the touch screen to effectuate a change in a parameter associated with the operation of the machine or the treatment session. The user interface is connected to a central computer control system having a host microprocessor and a backup safety microprocessor. The hard key is directly wired to the safety microprocessor. After the user selects a new parametric value on the touch screen, the user presses a hard key. The host and safety microprocessors implement a verification routine to insure that the entered parameter is appropriate for the patient's treatment and the display on the touch screen. If the verification procedure ends in a positive result, the user is prompted to presses a second hard key to confirm the change, causing an additional verification check to be preformed. If the additional verification check is successful, the parametric value is entered into a memory (such as a hard disk) storing instructions for operation of the medical instrument.

9. 发明公开

EP1457219A1 Cutter for partially cutting a membrane 审中-公开
标题翻译： Vorrichtung zum teilweisen Schneiden einer膜
公开(公告)号：EP1457219A1
公开(公告)日：2004-09-15
申请号：EP04014467.7
申请日：1999-12-21
申请人： TEIJIN LIMITED , Aksys, Ltd.
发明人： The designation of the inventor has not yet been filed
IPC分类号： A61M1/16
CPC分类号： A61M1/1656 , A61M1/1666 , A61M1/1668 , B67B7/38 , Y10T83/7851 , Y10T83/788 , Y10T83/814 , Y10T83/9382 , Y10T83/9387 , Y10T83/9418 , Y10T137/1759
摘要： The invention relates to a cutter for partially cutting a membrane along a periphery of an opening of a vessel which contains at least one medicament in the form of powder and defines a bottom, a side wall, and a top opening which is closed by a membrane for sealing the inside of the vessel after the vessel receives a predetermined.amount of the medicament, the cutter comprising;
a cutter body substantially in the form of a hollow cylinder having an inclined end;
a cutting edge provided along the inclined end;
a slit extending from the inclined end into the cutter body.
摘要翻译：本发明涉及一种用于沿着容器的开口的周边部分地切割膜的切割器，该切割器包含至少一种粉末形式的药剂并且限定底部，侧壁和顶部开口，所述顶部开口由膜封闭用于在容器接收到预定数量的药物之后密封容器的内部，所述切割器包括：基本上为具有倾斜端的中空圆筒形式的切割器主体; 沿倾斜端设置的切削刃; 从倾斜端部延伸到切割器主体的狭缝。

10. 发明授权

EP1140251B1 Opener for opening the membrane of a medicament vessel 有权
标题翻译：开瓶器用于打开药物容器的膜
公开(公告)号：EP1140251B1
公开(公告)日：2004-07-21
申请号：EP99959932.7
申请日：1999-12-21
申请人： TEIJIN LIMITED , Aksys, Ltd.
发明人： MORIYAMA, Naohiko , YANO, Tetsuya, Teijin Ltd., , IMAI, Ken, Teijin Ltd , DEGUCHI, Tsuneo, Teijin Ltd
IPC分类号： A61M1/16
CPC分类号： A61M1/1656 , A61M1/1666 , A61M1/1668 , B67B7/38 , Y10T83/7851 , Y10T83/788 , Y10T83/814 , Y10T83/9382 , Y10T83/9387 , Y10T83/9418 , Y10T137/1759

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