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1. 发明授权

EP3959103B1 SYSTEMS AND METHODS FOR MOBILE MOLDING AND BONDING 有权
公开(公告)号：EP3959103B1
公开(公告)日：2024-08-14
申请号：EP20796137.6
申请日：2020-04-06
IPC分类号： B29C44/34 , B29C33/34 , B29C44/58 , A63B69/00 , B60P3/14 , A63B71/04 , A63B71/06 , B29C44/14
CPC分类号： A63B2220/83320130101 , A63B2225/7420200801 , A63B71/0622 , A63B2071/062720130101 , A63B71/04 , A63B2225/5020130101 , A63B69/0048 , B29C44/3415 , B29C33/34 , B29C44/14 , B29C44/58

2. 发明公开

EP4371613A3 COMPOUNDS FOR USE IN THE TREATMENT OF OCULAR PAIN 审中-公开
公开(公告)号：EP4371613A3
公开(公告)日：2024-07-24
申请号：EP24166426.7
申请日：2019-02-26
申请人： Ospedale San Raffaele S.r.l.
发明人： RAMA, Paolo , FERRARI, Giulio
IPC分类号： A61K31/00 , A61K31/5377 , A61K31/675 , A61K45/06 , A61P29/00 , A61P27/02
CPC分类号： A61K31/00 , A61K31/5377 , A61K31/675 , A61K45/06 , A61P27/02 , A61P29/00
摘要： The invention relates to compounds, in particular NK-1 antagonists, for use in the treatment of ocular sensitivity and/or ocular pain.

3. 发明公开

EP4379066A1 PRODUCT MATERIAL LEATHER FABRICS PHYSICALLY EXTRACTED FROM COWHIDE 审中-实审
公开(公告)号：EP4379066A1
公开(公告)日：2024-06-05
申请号：EP22940498.3
申请日：2022-10-12
申请人： Atkoplanning Inc.
发明人： KIM, Ji Eon , CHOI, Bong Jin
IPC分类号： C14B7/04 , C14B7/06 , D02G3/04
摘要： The present invention relates to leather fibers for product materials, physically extracted from cowhide, and more specifically, the leather fibers are easily obtained for each length so that there is an advantage in that the leather fibers having different lengths can be respectively used as materials more appropriately for various articles such as leather sheets or yarns.

4. 发明公开

EP4326093A1 COMPOSITION COMPRISING A PHYTOCOMPLEX FROM POMEGRANATE AND ITS USES 审中-实审
公开(公告)号：EP4326093A1
公开(公告)日：2024-02-28
申请号：EP22724762.4
申请日：2022-04-22
申请人： Esserre Pharma Srl
发明人： RICCIONI, Costanza Valentina , SQUILLACE GRECO, Amedeo
IPC分类号： A23L33/105 , A23L33/15 , A23L33/155 , A61K8/9789 , A61K31/375 , A61K31/4415 , A61K31/51 , A61K31/525 , A61K31/592 , A61K31/593 , A61K31/714 , A61K36/185 , A61P11/00 , A61P17/18 , A61P31/00

5. 发明公开

EP4324970A2 SELF RISING BOARD MOLDING 审中-实审
公开(公告)号：EP4324970A2
公开(公告)日：2024-02-21
申请号：EP23217442.5
申请日：2020-03-16
申请人： Piana Nonwovens
发明人： Hollis, Andy , Defranks, Michael Stephen , Mccann, Eric , Jafari, Mehran , Andriessen, Helias , Lim, Sang-Hoon , Piana, Andreas , Borgatti, Alfio
IPC分类号： D04H1/54
摘要： A three-dimensional component is produced in a simplified molding operation. Expandable substrates, which are referred to as blanks, are created by compressing thermobonded nonwovens after heating the binder material above its melting temperature, and then cooling the compressed nonwovens so that the binder material hardens and holds the fibers of the nonwoven together in a compressed configuration with stored kinetic energy. Boards can be formed by laminating two or more blanks together and/or by laminating the blanks with other materials, including non-expendable materials. A mold for the component to be manufactured can be partially filled with a number of boards (or blanks) in a stacked, vertically, adjacent or even random orientation. In addition, the boards or blanks may be cut to create desired shapes of parts that can be placed in the mold. Upon application of heat to the boards or blanks or parts in the mold, the binder material is melted so as to allow the nonwoven material to expand in one or more directions, and thereby fill all or part of the mold. Upon cooling, the binder material again hardens, and the molded component is retrieved from the mold. Depending on the nature of the boards used, i.e., they may be the same or different from each other both in materials and configuration, physical attributes of the molded component can be achieved in a tailored fashion. For example, a seat or mattress may include an expanded and softer top layer of nonwoven, under which is a relatively harder layer of vertically lapped nonwoven or other material, etc. Steam heating for expanding the self-rising board is improved by controlling the rate of admission of the steam to the mold which is used to expand the expandable substrates, as well as applying a vacuum pressure to the mold after expansion of the expandable substrates.

6. 发明公开

EP4251060A1 PORTABLE VESSEL SCANNER 审中-实审
公开(公告)号：EP4251060A1
公开(公告)日：2023-10-04
申请号：EP21830756.9
申请日：2021-11-19
申请人： Università degli Studi della Campania "Luigi Vanvitelli"
发明人： MARFELLA, Raffaele , PAOLISSO, Giuseppe , PAOLISSO, Pasquale , SARDU, Celestino , ZENI, Luigi , VALLIFUOCO, Raffaele
IPC分类号： A61B8/00 , A61B8/08 , A61B17/34

7. 发明授权

EP3942686B1 ELECTRONIC DEVICE AND METHOD FOR THE MAXIMIZATION OF THE AVERAGE POWER EXTRACTED FROM A VIBRATION HARVESTER 有权
公开(公告)号：EP3942686B1
公开(公告)日：2023-09-13
申请号：EP20719490.3
申请日：2020-03-19
发明人： LO SCHIAVO, Alessandro , VITELLI, Massimo , COSTANZO, Luigi
IPC分类号： H02N2/18 , H02K35/00

8. 发明公开

EP4066823A1 REDUCED CALORIC INTAKE AND ANTICANCER AGENTS FOR THE TREATMENT OF CANCER 审中-实审
公开(公告)号：EP4066823A1
公开(公告)日：2022-10-05
申请号：EP21165778.8
申请日：2021-03-30
申请人： IFOM Fondazione Istituto Firc di Oncologia Molecolare
发明人： LONGO, Valter , SALVADORI, Giulia
IPC分类号： A61K31/00 , A61K31/436 , A61K31/4439 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/7004 , A61P35/00 , G01N33/50
摘要： The present invention relates to the use of fasting mimicking diet (FMD) to inhibit growth and/or kill cancer stem cells (CSCs) in combination with at least one anticancer agent selected from: an AKT inhibitor, an hexokinase inhibitor, a PI3K inhibitor, a combination of a PI3K inhibitor and a CDK4/6 inhibitor, or a combination of a mTOR inhibitor and a PI3K inhibitor. FMD in combination with said anticancer agent is particularly effective in the treatment of triple negative breast cancer (TNBC) and reduces cancer stem cells (CSCs) escape pathways. The invention further relates to a method to identify starvation escape pathways in cancer cells, which can be targeted by drugs.

9. 发明公开

EP4050002A1 ANTI-PROLIFERATIVE AGENTS 无效
公开(公告)号：EP4050002A1
公开(公告)日：2022-08-31
申请号：EP21159563.2
申请日：2021-02-26
申请人： First Health Pharmaceuticals B.V.
发明人： Andreini, Matteo , Bakker, Jan Willem , Tarditi, Alessia
IPC分类号： C07D271/107 , C07D413/10 , C07D413/14 , A61P35/00 , A61P1/08 , A61K31/4245
摘要： The present invention relates to compounds of formula (I) and to salts, solvates, stereoisomers and tautomers thereof useful as anti-proliferative agents and/or as inhibitors of DEAD-box (DDX) RNA helicases. The present invention also provides: uses of such compounds, particularly for the prevention and/or treatment of hyperproliferative disorders, pharmaceutical compositions comprising such compounds and processes for the manufacture thereof.

10. 发明公开

EP4003313A1 ACTIVATORS OF SIRTUINS AND USES THEREOF 审中-实审
公开(公告)号：EP4003313A1
公开(公告)日：2022-06-01
申请号：EP20744080.1
申请日：2020-07-29
申请人： Epi-C S.r.L.
发明人： ALTUCCI, Lucia , NEBBIOSO, Angela , SCISCIOLA, Lucia
IPC分类号： A61K31/00 , C07D311/00 , C07D311/16

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