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1. 发明公开

EP3348990A1 METHOD AND KIT FOR PURIFYING NUCLEIC ACIDS 审中-公开
公开(公告)号：EP3348990A1
公开(公告)日：2018-07-18
申请号：EP18160002.4
申请日：2013-08-27
申请人： Akonni Biosystems, Inc.
发明人： HOLMBERG, Rebecca , GINDLESPERGER, Alissa, Erin , STOKES, Tinsley, Janna , BELGRADER, Phillip
IPC分类号： G01N1/34 , C12Q1/68 , G01N33/48
CPC分类号： B01L3/0275 , B01L2200/0631 , B01L2300/0681 , C12N15/1017 , C12Q1/6806 , C12Q2523/308
摘要： Methods for automated extraction of nucleic acids are disclosed. The method includes flowing the plasma sample through a first filter under conditions that allow binding of the low and high-molecular weight DNA to the first filter; eluting the low and high-molecular weight DNA bound to the first filter to produce a concentrated nucleic acid sample; flowing the concentrated nucleic acid sample through a second filter under conditions that allow preferential binding of the high-molecular weight DNA to the second filter; and recovering the low-molecular weight DNA from the concentrated nucleic acid sample that flow through the second filter.

2. 发明授权

EP2652508B1 THE USE OF ANTI-CXCL13 AND ANTI-CXCR5 ANTIBODIES FOR THE TREATMENT OR DETECTION OF CANCER 有权
标题翻译：抗-CXCL13和抗CXCR5抗体用于治疗或检测癌症的用途
公开(公告)号：EP2652508B1
公开(公告)日：2018-02-07
申请号：EP11849217.2
申请日：2011-12-07
申请人： Jyant Technologies, Inc.
发明人： LILLARD, James W. , SINGH, Shailesh , SINGH, Rajesh
IPC分类号： G01N33/574 , G01N33/68 , G01N33/53
CPC分类号： G01N33/57407 , G01N2333/7158
摘要： The use of anti-CXCL13 and anti-CXCR5 antiboies for the treatment or dectection of in a subject is disclosed.

3. 发明公开

EP3039191A1 FLOOD DEFENCE BARRIER 审中-公开
标题翻译： FLUTABWEHRBARRIERE
公开(公告)号：EP3039191A1
公开(公告)日：2016-07-06
申请号：EP14758637.4
申请日：2014-08-29
申请人： Hesco Bastion Limited
发明人： PICKUP, Mike , SCOTT, Kenny
IPC分类号： E02B3/10
CPC分类号： E02B3/108 , B65D88/1625 , E02B3/12 , E02D17/18 , E02D29/025 , E02D29/0266 , E02D29/0291
摘要： Also provided is a multi-compartmental foldable barrier structure comprising a multiplicity of such compartments connected, affixed or adhered to one another end to end, as well as a flood defence barrier comprising a first multi-compartmental foldable barrier structure provided with a continuous length of water impermeable material extending across the individual structures along at least one side of the barrier; a second multi-compartmental foldable barrier structure provided with a continuous length of water impermeable material extending across the individual structures along at least one side of the barrier; and fastening means for fastening the first multi-compartmental foldable barrier structure to the second multi-compartmental foldable barrier structure.
摘要翻译：本发明提供一种防洪屏障，其包括通过第一不可释放的紧固装置连接的第一多个独立隔室，其中所述多个独立的隔室包括至少一个第二可释放的紧固装置，其有效地可释放地紧固第一多个单独的隔间到第二多个单独隔间。还提供了一种防洪屏障，其包括连接在一起的第一多个单独的隔间，并且设置有连续长度的不透水材料，沿着屏障的至少一侧延伸穿过各个隔室，连接在一起并提供的第二多个单独隔室具有连续长度的不透水材料，沿着屏障的至少一侧延伸穿过各个隔室，以及紧固装置，用于将第一多个单独的隔间紧固到第二多个单独的隔间，以及部署所述防洪的方法屏障及其用途。

4. 发明公开

EP3038949A1 FOLDABLE BARRIER STRUCTURE 审中-公开
标题翻译： FALTBARE SPERRSTRUKTUR
公开(公告)号：EP3038949A1
公开(公告)日：2016-07-06
申请号：EP14758635.8
申请日：2014-08-29
申请人： Hesco Bastion Limited
发明人： PICKUP, Mike , SCOTT, Kenny
IPC分类号： B65D88/16 , E02B3/10
CPC分类号： E02B3/108 , B65D88/1625 , E02B3/12 , E02D17/18 , E02D29/025 , E02D29/0266 , E02D29/0291
摘要： Also provided is a multi-compartmental foldable barrier structure comprising a multiplicity of such compartments connected, affixed or adhered to one another end to end, as well as a flood defence barrier comprising a first multi-compartmental foldable barrier structure provided with a continuous length of water impermeable material extending across the individual structures along at least one side of the barrier; a second multi-compartmental foldable barrier structure provided with a continuous length of water impermeable material extending across the individual structures along at least one side of the barrier; and fastening means for fastening the first multi-compartmental foldable barrier structure to the second multi-compartmental foldable barrier structure.
摘要翻译：本发明提供一种防洪屏障，其包括通过第一不可释放的紧固装置连接的第一多个独立隔室，其中所述多个独立的隔室包括至少一个第二可释放的紧固装置，其有效地可释放地紧固第一多个单独的隔间到第二多个单独隔间。还提供了一种防洪屏障，其包括连接在一起的第一多个单独的隔间，并且设置有连续长度的不透水材料，沿着屏障的至少一侧延伸穿过各个隔室，连接在一起并提供的第二多个单独隔室具有连续长度的不透水材料，沿着屏障的至少一侧延伸穿过各个隔室，以及紧固装置，用于将第一多个单独隔室紧固到第二多个独立的隔间，以及部署所述防洪的方法屏障及其用途。

5. 发明公开

EP2952510A1 SUBSTITUTED 2-AMINOPYRIDINE PROTEIN KINASE INHIBITOR 有权
标题翻译：取代的2-氨基吡啶蛋白激酶抑制剂
公开(公告)号：EP2952510A1
公开(公告)日：2015-12-09
申请号：EP14746385.5
申请日：2014-01-27
申请人： Chia Tai Tianqing Pharmaceutical Group Co.,Ltd , Centaurus BioPharma Co., Ltd. , Lianyungang Runzhong Pharmaceutical Co., Ltd.
发明人： XIAO, Dengming , XU, Xinhe , LIU, Xijie , HU, Yuandong , YU, Honghao , LIU, Zhihua , PENG, Yong , SUN, Yinghui , LUO, Hong , KONG, Fansheng , HAN, Yongxin , SUN, Jian
IPC分类号： C07D401/04 , C07D213/74 , C07D401/06 , C07D401/14 , C07D213/73 , C07F9/6558 , A61K31/496 , A61K31/675 , A61K31/4545 , A61K31/5377 , A61K31/444 , A61K31/506 , A61P35/00
CPC分类号： C07D401/14 , A61K31/444 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/675 , C07D213/73 , C07D213/74 , C07D401/04 , C07D401/06 , C07F9/65583
摘要： Disclosed are a 2-aminopyridine derivative having protein kinase inhibition activity, a preparation method and a pharmaceutical composition thereof Also disclosed are uses of the compounds and the pharmaceutical compositions thereof in the preparation of drugs for treating and/or preventing protein kinase-related diseases.
摘要翻译：公开了具有蛋白激酶抑制活性的2-氨基吡啶衍生物，其制备方法和药物组合物。还公开了所述化合物及其药物组合物在制备用于治疗和/或预防蛋白激酶相关疾病的药物中的用途。

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