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1. 发明授权

EP0843735B1 GLYCOSYLASE MEDIATED DETECTION OF KNOWN NUCLEOTIDE SEQUENCES 失效
标题翻译：具体核酸序列的糖基化酶使用的检测
公开(公告)号：EP0843735B1
公开(公告)日：2002-07-17
申请号：EP95942776.6
申请日：1995-12-21
申请人： Forfas (trading as Bioresearch Ireland) , University College Cork-National University of Ireland, Cork
发明人： McCARTHY, Thomas, Valentine , VAUGHAN, Patrick, Martin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6834 , C12Q1/6827 , C12Q1/6853 , C12Q1/689 , C12Q2600/156
摘要： A method for rapidly detecting the presence or absence of a particular nucleic acid sequence at a candidate locus in a target nucleic acid sample comprises the steps of: i) introducing a modified base which is a substrate for a DNA glycosylase into said candidate locus at one or more preselected positions; ii) excising the modified base by means of said DNA glycosylase so as to generate an abasic site; iii) cleaving phosphate linkages at abasic sites generated in step ii); and iv) analysing the cleavage products of step iii) so as to identify in said target nucleic acid sequence the presence or absence of said particular nucleic acid sequence at said candidate locus. The method has particular application for detecting specific mutations in a DNA sample, including the detection of multiple known mutations in DNA. Large throughput of sample can be achieved rapidly and easily.

2. 发明公开

EP1058092A2 A data capture system 审中-公开
标题翻译： Dataerwerbungssystem
公开(公告)号：EP1058092A2
公开(公告)日：2000-12-06
申请号：EP00650057.3
申请日：2000-05-24
申请人： FORFAS, (trading as PEI Technologies)
发明人： Leahy, Martin J. , Byrne, Catherine , Clothier, Stephen , O'Regan, Gerard , Samways, Philip , Punch, Jeffrey , Davies, Mark
IPC分类号： G01D3/08
CPC分类号： G01D3/08
摘要： A data capture system (1) has modular amplifier circuits (10) connected to modular capture circuits (11) within a rotor 2. Each capture circuit (11) has an FPGA (26) operation according to low-frequency and high-frequency state machines (M1, M2) to control ADCs (25) and upload from memories (30) to a host (15). During sampling, each FPGA (26) runs through a ready mode, a sampling mode, and again a ready mode according to a host command.
摘要翻译：数据采集系统（1）具有连接到转子2内的模块化捕获电路（11）的模块化放大器电路（10）。每个捕获电路（11）具有根据低频和高频状态的FPGA（26）操作机器（M1，M2）以控制ADC（25）并从存储器（30）上传到主机（15）。在采样期间，每个FPGA（26）根据主机命令运行就绪模式，采样模式以及再次就绪模式。

3. 发明公开

EP0888629A1 PRODUCTION OF HARD MAGNETIC MATERIAL FILMS 失效
标题翻译：生产硬磁材料电影
公开(公告)号：EP0888629A1
公开(公告)日：1999-01-07
申请号：EP97915661.0
申请日：1997-03-19
申请人： FORFAS, (trading as PEI Technologies)
发明人： MURRAY, Christopher, Patrick, "Hideaway 2" , O'MATHUNA, Sean, Cian
IPC分类号： H01F41
CPC分类号： H01F41/16
摘要： Magnetic films for very small magnetic devices are produced by applying a paste to a substrate and curing it. The paste has magnetic particles in a binder which has binding particles dissolved in a solvent. The solvent evolves during curing and thus the cured film has a very high magnetic density. The method of curing ensures that porosity does not arise to a significant extent.

4. 发明授权

EP0466428B1 Method and apparatus for conveying ice lumps 失效
标题翻译：用于输送冰块的方法和装置
公开(公告)号：EP0466428B1
公开(公告)日：1997-05-28
申请号：EP91306167.7
申请日：1991-07-08
申请人： FORFAS
发明人： Reinhardt, Robert Christopher , Humphreys, Richard Macartan
IPC分类号： F25C5/00 , B65G53/06
CPC分类号： B65G53/60 , B65G53/06 , B65G53/525 , F25C5/20
摘要： In apparatus for conveying batches of ice lumps from a storage hopper (2) to remotely located ice dispensers (7), ice lumps from the storage hopper (2) are delivered into the main conduits (5) through corresponding main valves (20) and connecting conduits (25) extending between each main valve (20) and the storage hopper (2). Metering valves (14) meter batches of ice lumps of predetermined size into the main conduits (5). Conveying air from an air blower (10) is supplied to the main conduits (5) through the main valves (20) for conveying the batches of ice lumps. In use, batches of ice lumps are intermittently delivered into the main conduit (5), and the batches of ice lumps and conveying air are alternately supplied to the main conduit (5).

5. 发明授权

EP0843735B2 GLYCOSYLASE MEDIATED DETECTION OF KNOWN NUCLEOTIDE SEQUENCES 失效
标题翻译：具体核酸序列的糖基化酶使用的检测
公开(公告)号：EP0843735B2
公开(公告)日：2006-12-27
申请号：EP95942776.6
申请日：1995-12-21
申请人： Forfas (trading as Bioresearch Ireland) , University College Cork-National University of Ireland, Cork
发明人： McCARTHY, Thomas, Valentine , VAUGHAN, Patrick, Martin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6834 , C12Q1/6827 , C12Q1/6853 , C12Q1/689 , C12Q2600/156
摘要： A method for rapidly detecting the presence or absence of a particular nucleic acid sequence at a candidate locus in a target nucleic acid sample comprises the steps of: i) introducing a modified base which is a substrate for a DNA glycosylase into said candidate locus at one or more preselected positions; ii) excising the modified base by means of said DNA glycosylase so as to generate an abasic site; iii) cleaving phosphate linkages at abasic sites generated in step ii); and iv) analysing the cleavage products of step iii) so as to identify in said target nucleic acid sequence the presence or absence of said particular nucleic acid sequence at said candidate locus. The method has particular application for detecting specific mutations in a DNA sample, including the detection of multiple known mutations in DNA. Large throughput of sample can be achieved rapidly and easily.

6. 发明公开

EP1058092A3 A data capture system 审中-公开
标题翻译： Dataerwerbungssystem
公开(公告)号：EP1058092A3
公开(公告)日：2005-01-19
申请号：EP00650057.3
申请日：2000-05-24
申请人： FORFAS, (trading as PEI Technologies)
发明人： Leahy, Martin J. , Byrne, Catherine , Clothier, Stephen , O'Regan, Gerard , Samways, Philip , Punch, Jeffrey , Davies, Mark
IPC分类号： G01D3/08 , G01D1/00
CPC分类号： G01D3/08
摘要： A data capture system (1) has modular amplifier circuits (10) connected to modular capture circuits (11) within a rotor 2. Each capture circuit (11) has an FPGA (26) operation according to low-frequency and high-frequency state machines (M1, M2) to control ADCs (25) and upload from memories (30) to a host (15). During sampling, each FPGA (26) runs through a ready mode, a sampling mode, and again a ready mode according to a host command.

7. 发明公开

EP1164689A3 A single stage ac/dc converter 审中-公开
标题翻译：单级AC / DC转换器
公开(公告)号：EP1164689A3
公开(公告)日：2003-09-10
申请号：EP01650072.0
申请日：2001-06-13
申请人： FORFAS, (trading as PEI Technologies)
发明人： O'Sullivan, Dara, Pei Technologies , Egan, Michael, Pei Technologies , Willers, Michael, Pei Technologies
IPC分类号： H02M1/00 , H02M7/155
CPC分类号： H02M1/4258 , Y02B70/126
摘要： An ac/dc converter (1) has a closed loop controller (3) to maintain a well regulated output voltage (V o ) with low peak-to-peak ripple. A resonant capacitor ( C in ) across the rectifier bridge ( D R1 -D R4 ), and a resonant inductor ( L R ) between the bridge and the isolation transformer provide inherent power factor correction. A clamping diode ( D CL ) is connected between the dc rectifier bridge positive terminal and the bulk capacitor ( C B ). There is also a second resonant capacitor ( C t ) across the isolation transformer. There is zero voltage switching of the power switches ( Q1 , Q2 ).

8. 发明公开

EP0466428A2 Method and apparatus for conveying ice lumps 失效
标题翻译： Verfahren undGerätzumFördernvonEisstücken。
公开(公告)号：EP0466428A2
公开(公告)日：1992-01-15
申请号：EP91306167.7
申请日：1991-07-08
申请人： FORFAS
发明人： Reinhardt, Robert Christopher , Humphreys, Richard Macartan
IPC分类号： F25C5/00 , B65G53/06
CPC分类号： B65G53/60 , B65G53/06 , B65G53/525 , F25C5/20
摘要： In apparatus for conveying batches of ice lumps from a storage hopper (2) to remotely located ice dispensers (7), ice lumps from the storage hopper (2) are delivered into the main conduits (5) through corresponding main valves (20) and connecting conduits (25) extending between each main valve (20) and the storage hopper (2). Metering valves (14) meter batches of ice lumps of predetermined size into the main conduits (5). Conveying air from an air blower (10) is supplied to the main conduits (5) through the main valves (20) for conveying the batches of ice lumps. In use, batches of ice lumps are intermittently delivered into the main conduit (5), and the batches of ice lumps and conveying air are alternately supplied to the main conduit (5).
摘要翻译：在用于将存储料斗（2）中的批块冰块输送到位于远处的分配器（7）的设备中，来自储存料斗（2）的冰块通过相应的主阀（20）和在每个主阀（20）和存储料斗（2）之间延伸的连接管道（25）。计量阀（14）将预定尺寸的冰块的批量计量到主管道（5）中。通过主阀（20）将从空气鼓风机（10）输送的空气供给到主管道（5），以输送多个冰块。在使用中，批量的冰块被间歇地输送到主管道（5）中，并且批量的冰块和输送空气交替地供应到主管道（5）。

9. 发明公开

EP1321117A2 Contrast bathing physiotherapy device 审中-公开
标题翻译： Wechselbadphysiotherapiegerät
公开(公告)号：EP1321117A2
公开(公告)日：2003-06-25
申请号：EP02394118.0
申请日：2002-12-19
申请人： FORFAS, (trading as PEI Technologies)
发明人： Dalton, Tara , Punch, Jeff
IPC分类号： A61F7/00
CPC分类号： A61F7/007 , A61F2007/0001 , A61F2007/0054 , A61F2007/0076 , A61F2007/0295
摘要： A contrast bathing physiotherapy device (1) has local thermoelectric cells (7) which heat or cool a localised part of a patient's body (B) via a Cu heat spreader 6 and a flexible thermal interface pad (15). Cooling is augmented by a bias bank (21) of thermoelectric cells which draw heat from the local bank (7) via a looped heat pipe (10). The heat pipe (10) has an evaporator in a Cu block (8) at the local bank (7) and a condenser in a Cu block (20) at the bias bank (21).
摘要翻译：对比洗浴物理治疗装置（1）具有局部热电池（7），其通过Cu散热器6和柔性热界面垫（15）加热或冷却患者身体（B）的局部部分。通过热电池的偏压组（21），通过环形热管（10）从本地组（7）抽取热量来增加冷却。热管（10）在本地堤（7）处的Cu块（8）中具有蒸发器，并且在偏置堤（21）处具有Cu块（20）中的冷凝器。

10. 发明公开

EP1014550A2 An AC/DC converter 审中-公开
标题翻译： AC-DC Wandler
公开(公告)号：EP1014550A2
公开(公告)日：2000-06-28
申请号：EP99650118.5
申请日：1999-12-17
申请人： FORFAS, (trading as PEI Technologies)
发明人： Morrison, Richard Joseph , Egan, Michael Gerard
IPC分类号： H02M3/335 , H02M1/00 , H02J7/02
CPC分类号： H02M1/4208 , H02M3/33592 , H02M7/219 , H02M2001/007 , Y02B70/126 , Y02B70/1475
摘要： An ac/dc converter has a two switch buck boost (2SBB) ac/dc stage (2) integrated with an isolated full or half-bridge dc/dc stage (3). A modulator (4, 25) for the 2SBB input switch (Q 1 ) controls the current in the power transfer inductor of the 2SBB. It causes dis-continuity of the current while minimising its peak level by exerting control on both turn-on and turn-off of the input switch. An intermediate dc voltage generated by the 2SBB has a level below that of the maximum peak input voltage and control is exerted over the inrush current.
摘要翻译：交流/直流转换器具有与隔离的全桥或半桥直流/直流级（3）集成的双开关降压升压（2SBB）交流/直流级（2）。用于2SBB输入开关（Q1）的调制器（4,25）控制2SBB的功率传递电感器中的电流。它通过对输入开关的导通和关断进行控制来使电流不连续，同时使其峰值电平最小化。由2SBB产生的中间直流电压的电平低于最大峰值输入电压的电平，并且控制在浪涌电流上施加。

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