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81. 发明公开

EP2414026A2 METHOD AND APPARATUS FOR TREATING OBESITY AND CONTROLLING WEIGHT GAIN USING SELF-EXPANDING INTRAGASTRIC DEVICES 审中-公开
标题翻译：方法和一种用于治疗肥胖和体重增加控制的使用自胃内DEVICES
公开(公告)号：EP2414026A2
公开(公告)日：2012-02-08
申请号：EP10762111.2
申请日：2010-03-24
申请人： Onciomed, Inc. , Nihalani, Raj
发明人： NIHALANI, Raj
IPC分类号： A61M29/02 , A61F2/02 , A61L27/04 , A61L27/06 , A61L27/14
CPC分类号： A61F5/0036
摘要： The invention generally relates to a method and apparatus to treat obesity and controlling weight gain. In an exemplary embodiment, the invention relates to a covered cage device that is implanted within a human's stomach to occupy volume and cause a reduced desire for eating. The covered cage device is made from a wire-mesh, such a Nitinol, and can be adjustable and collapsible. In another embodiment, the covered cage device has edges that provide stimulation to the stomach to induce a feeling of fullness.

82. 发明公开

EP2361588A3 Arrangement with an implant and/or a unit belonging to said implant, and method for production of the implant and/or unit 审中-公开
标题翻译：装置与植入物和/或属于所述植入物的单元，并且使植入物和/或单元的方法
公开(公告)号：EP2361588A3
公开(公告)日：2011-12-14
申请号：EP10009890.4
申请日：2004-12-06
申请人： Nobel Biocare Services AG
发明人： Hall, Jan
IPC分类号： A61C8/00 , A61L27/06 , A61L27/50
CPC分类号： A61C13/0012 , A61C8/0012 , A61C8/0013 , A61C8/0015 , A61K6/0235 , A61L27/06 , A61L27/50 , C25D11/022 , C25D11/26
摘要： An implant (5, 13) and/or a unit (9), e.g. spacer sleeve, belonging to said implant is/are intended to extend through a hole (4') formed in a jaw bone (2) and through soft tissue (3) belonging to the jaw bone and to comprise one or more outer layers of principally titanium dioxide. Each layer consists of crystalline titanium dioxide which largely or completely assumes the anatase phase. The invention also relates to a method for production of such a dental implant (5, 13) and/or of a unit (9) belonging to it, which has one or more outer layers of titanium dioxide. The method is an anodic oxidation method in which the part or parts bearing the outer layer(s) is/are applied to electrolyte under voltage, e.g. comprising sulfuric acid and phosphoric acid, and the voltage (U) and the dwell time of the part or parts in the electrolyte are chosen such that titanium dioxide, largely or completely assuming the crystalline anatase phase, is formed. Excellent bone guidance and soft tissue integration can be achieved in this way.
摘要翻译：的植入物（5，13）和/或一个单元（9），例如间隔套筒，属于所述植入物/旨在通过在颚骨（2），并通过软组织形成的孔（4“）至（3）延伸属于颚骨和为包括主要地一个或多个外层二氧化钛。晶体二氧化钛的每一层besteht这在很大程度上或完全呼叫übernimmt锐钛矿相。因此本发明涉及一种用于生产寻求牙科植入物（5，13）和/或（9）属于它的单元，其中有二氧化钛的一个或多个外层的。该方法是阳极氧化方法，其中所述部分或部件的轴承外层（多个）/施加到电解质欠压，E.G. 包含硫酸和磷酸，和电压（U）和在电解质中的部分或部件中的停留时间被选择搜索做二氧化钛，大部分或全部呼叫假设晶体锐钛矿相，被形成。优秀的骨引导和软组织的整合可以通过这种方式来实现。

83. 发明公开

EP2361588A2 Arrangement with an implant and/or a unit belonging to said implant, and method for production of the implant and/or unit 审中-公开
标题翻译：具有属于所述植入物的植入物和/或单元的装置，以及用于生产植入物和/或单元的方法
公开(公告)号：EP2361588A2
公开(公告)日：2011-08-31
申请号：EP10009890.4
申请日：2004-12-06
申请人： Nobel Biocare Services AG
发明人： Hall, Jan
IPC分类号： A61C8/00 , A61L27/06 , A61L27/50
CPC分类号： A61C13/0012 , A61C8/0012 , A61C8/0013 , A61C8/0015 , A61K6/0235 , A61L27/06 , A61L27/50 , C25D11/022 , C25D11/26
摘要： An implant (5, 13) and/or a unit (9), e.g. spacer sleeve, belonging to said implant is/are intended to extend through a hole (4') formed in a jaw bone (2) and through soft tissue (3) belonging to the jaw bone and to comprise one or more outer layers of principally titanium dioxide. Each layer consists of crystalline titanium dioxide which largely or completely assumes the anatase phase. The invention also relates to a method for production of such a dental implant (5, 13) and/or of a unit (9) belonging to it, which has one or more outer layers of titanium dioxide. The method is an anodic oxidation method in which the part or parts bearing the outer layer(s) is/are applied to electrolyte under voltage, e.g. comprising sulfuric acid and phosphoric acid, and the voltage (U) and the dwell time of the part or parts in the electrolyte are chosen such that titanium dioxide, largely or completely assuming the crystalline anatase phase, is formed. Excellent bone guidance and soft tissue integration can be achieved in this way.
摘要翻译：植入物（5,13）和/或单元（9），例如植入物属于所述植入物的间隔套旨在延伸穿过在颚骨（2）中形成的孔（4'）和穿过属于颚骨的软组织（3），并且主要包括一个或多个外层二氧化钛。每层由结晶二氧化钛组成，其大部分或完全呈现锐钛矿相。本发明还涉及用于生产这种牙科植入物（5,13）和/或属于它的单元（9）的方法，所述牙科植入物具有一个或多个二氧化钛外层。该方法是一种阳极氧化方法，其中承载外层的一个或多个部件在电压下施加到电解质上，例如，包含硫酸和磷酸，并且选择电解质中的部分或多个部分的电压（U）和停留时间以使得形成大部分或完全呈现结晶锐钛矿相的二氧化钛。通过这种方式可以实现出色的骨引导和软组织整合。

84. 发明公开

EP2111338A4 HYDROGEL-METAL ASSEMBLY 审中-公开
标题翻译：水凝胶-METAL安排
公开(公告)号：EP2111338A4
公开(公告)日：2011-08-10
申请号：EP08725292
申请日：2008-02-06
申请人： UNIV LELAND STANFORD JUNIOR
发明人： MYUNG DAVID , MUIR BEINN V O , FRANK CURTIS W
IPC分类号： B32B15/04 , A61L27/06 , A61L27/34
CPC分类号： A61L27/34 , A61L27/06 , A61L2400/18 , B32B15/04 , Y10T428/24355 , Y10T428/269 , Y10T428/31536 , Y10T428/31678

85. 发明公开

EP2303191A2 HYBRID ORTHOPEDIC IMPLANT 审中-公开
标题翻译：骨科混合型植入物
公开(公告)号：EP2303191A2
公开(公告)日：2011-04-06
申请号：EP09759218.2
申请日：2009-06-02
申请人： Skeletal Dynamics, LLC
发明人： ORBAY, Jorge, L. , NORMAN, Thomas, H. , DE QUEVEDO, William Garcia , ESPINOSA, Alejandro
IPC分类号： A61F2/28 , A61B17/60 , A61L27/06
CPC分类号： A61B17/80 , A61B17/8057 , A61B17/8085
摘要： A hybrid orthopedic implant is provided. The implant includes a hybrid plate including a metal skeleton engaged with a plastic covering. Holes passing through the hybrid plate receive screws therethrough, to secure the hybrid plate to bone.

86. 发明授权

EP1345637B1 SURFACE MODIFICATION OF IMPLANTS FOR HEALING IN BONE AND SOFT TISSUE 有权
标题翻译：种植体愈合骨和组织表面改性
公开(公告)号：EP1345637B1
公开(公告)日：2011-03-02
申请号：EP01272430.8
申请日：2001-12-21
申请人： TioTec AB
发明人： Nygren, Hakan
IPC分类号： A61L27/06
CPC分类号： A61L27/306 , A61L27/04 , A61L27/06 , A61L27/56 , A61L2400/18
摘要： The application describes an implant intended for incorporation in bone and soft tissue and comprising a metal or a semiconductor and a layer of a metal oxide or a semiconductor oxide on the surface of the metal/semiconductor/metal oxide or semiconductor/semiconductor oxide, where the oxide layer is hydrophobic and has pores. The application also describes a method for treating the surface of an implant according to the above.

87. 发明授权

EP2178466B1 NANOSURFACE 有权
标题翻译： NANOFLÄCHE
公开(公告)号：EP2178466B1
公开(公告)日：2011-01-12
申请号：EP08774897.6
申请日：2008-07-08
申请人： Astra Tech AB
发明人： PETERSSON, Ingela , FREDRIKSSON, Anette
IPC分类号： A61F2/30 , A61C8/00 , A61K6/04 , A61L27/04 , A61L27/06 , A61L27/30 , A61L27/50 , C23F1/26
CPC分类号： A61F2/30767 , A61C8/0012 , A61C2008/0046 , A61F2/3094 , A61F2002/30719 , A61F2002/30906 , A61F2002/30925 , A61F2002/30929 , A61F2250/0092 , A61F2310/00023 , A61F2310/00598 , A61F2310/00616 , A61L27/306 , A61L2400/12 , B82Y5/00 , B82Y30/00 , C23C8/00 , C23C8/10 , C23C22/46 , C23C26/00 , C23G1/106
摘要： The invention relates to a method for modification of a biocompatible component comprising the steps of a) providing a biocompatible component at least partly covered by metallic oxide; and b) treating at least a part of said component, which part is covered by said metallic oxide, with an aqueous composition comprising oxalic acid; whereby a modified metallic oxide is obtained. The invention also relates to a biocompatible component comprising a substrate having a surface comprising a) a microstructure comprising pits separated by plateus and/or ridges; and b) a primary nanostructure being superimposed on said microstructure, said primary nanostructure comprising depressions arranged in a wave-like formation.

88. 发明授权

EP1534168B1 AN IMPLANT AND A METHOD FOR TREATING AN IMPLANT SURFACE 有权转让
标题翻译：植入物和法治疗植入物表面的
公开(公告)号：EP1534168B1
公开(公告)日：2010-06-02
申请号：EP03723590.0
申请日：2003-05-06
申请人： Astra Tech AB
发明人： PETERSSON, Ingela , JUNEMO-BOSTRÖM, Kristina , JOHANSSON-RUDÉN, Gunilla , ANDERSSON, Fredrik , HANSSON, Stig , ELLINGSEN, Jan-Eirik
IPC分类号： A61C8/00 , A61F2/02 , A61L27/06
CPC分类号： A61L27/56 , A61C2008/0046 , A61F2/30767 , A61F2002/30836 , A61F2002/30838 , A61F2002/30906 , A61F2002/30925 , A61F2002/3097 , A61F2310/00023 , A61F2310/00059 , A61F2310/00089 , A61F2310/00095 , A61F2310/00125 , A61F2310/00131 , A61L2400/18 , A61L2430/02
摘要： The invention relates to a method for treating an implant surface intended for implantation into bone tissue wherein a microroughness comprising pores and peaks having a pore diameter of ≤ 1 µm, a pore depth of ≤ 500 nm, and a peak width, at half the pore depth, of from 15 to 150 % of the pore diameter is provided. The invention also relates to an implant comprising a surface having the above characteristics.

89. 发明授权

EP1912687B1 Blood pump, in particular pneumatic heart assist device 有权
标题翻译：血泵，尤其是气动装置的心脏辅助
公开(公告)号：EP1912687B1
公开(公告)日：2010-03-17
申请号：EP05802493.6
申请日：2005-11-10
申请人： Fundacja Rozwoju Kardiochirurgii , Instytut Metalurgii i Inzynierii Materialowej PAN , Joanneum Research Forschungsgesellschaft mbH
发明人： EBNER, Reinhold , KUSTOSZ, Roman , LACKNER, Jürgen, M. , MAJOR, Boguslaw , RELIGA, Zbigniew , STOLARZEWICZ, Bogdan , WALDHAUSER, Wolfgang , WIERZCHON, Tadeusz
IPC分类号： A61M1/10 , A61L27/06
CPC分类号： A61M1/1037 , A61M1/106 , A61M1/122

90. 发明公开

EP2143823A2 Open-celled metal implants with roughened surfaces 审中-公开
标题翻译： Metallimplantate mit offenen Zellen und aufgerautenOberflächen
公开(公告)号：EP2143823A2
公开(公告)日：2010-01-13
申请号：EP09251677.2
申请日：2009-06-29
申请人： DePuy Products, Inc.
发明人： Liu, Hengda Derek , Yang, Sophie Ziaofan
IPC分类号： C23F1/26 , A61F2/30 , A61L27/06 , A61L27/56 , B22F7/00
CPC分类号： C23F1/26 , A61F2/30767 , A61F2/38 , A61F2002/30011 , A61F2002/3092 , A61F2002/30925 , A61F2250/0023 , A61F2310/00023 , A61L27/06 , A61L27/50 , A61L27/56 , A61L2400/18 , B22F3/24 , B22F2003/244 , B22F2003/248 , C22C1/08
摘要： Processes for etching a porous titanium foam or porous titanium alloy foam involve immersing a clean, dry foam product in an aqueous acid solution comprising about 0.5 to about 5 volume percent HF and about 5 to about 20 volume percent HNO 3 for a time sufficient to achieve a desired surface roughness and heating the etched foam to remove residual titanates. The etching process increases the porosity at the surface of the foam but the etchant does not penetrate fully into the interior of the foam so that adequate mechanical properties are maintained. The etching process also increases the coefficient of friction at the foam surface. The foam may comprise an open-celled orthopaedic or dental implant, or may comprise a coating on the surface of a substrate.
摘要翻译：用于蚀刻多孔钛泡沫或多孔钛合金泡沫的方法包括将干净，干燥的泡沫产品浸入包括约0.5至约5体积％HF和约5至约20体积％HNO 3的酸性水溶液中足够长的时间所需的表面粗糙度并加热蚀刻的泡沫以除去残余的钛酸盐。蚀刻工艺增加了泡沫表面的孔隙率，但是蚀刻剂不能完全渗透到泡沫的内部，从而保持了足够的机械性能。蚀刻工艺也增加了泡沫表面的摩擦系数。泡沫可以包括开孔矫形或牙科植入物，或者可以包括在基底表面上的涂层。

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