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81. 发明公开

EP3320107A1 ELECTROCHEMICALLY ACTIVE AGENTS FOR PH MODULATION IN BIOLOGICAL BUFFERS 审中-公开
标题翻译：电化学活性剂用于生物缓冲液PH调节
公开(公告)号：EP3320107A1
公开(公告)日：2018-05-16
申请号：EP16733550.4
申请日：2016-06-30
申请人： Robert Bosch GmbH
发明人： MARUNIAK, Autumn , AHMAD, Habib , RAGHUNATHAN, Ashwin , JOHNSON, Christopher , KAVUSI, Sam , FOMINA, Nadezda , LANG, Christoph
IPC分类号： C12Q1/00 , G01N33/543 , C07C37/00
CPC分类号： G01N27/4167 , C07C37/00 , C07C37/07 , C07C39/10 , C07C39/11 , C07C41/01 , C07C41/24 , C07C41/30 , C07C43/1783 , C07C43/2055 , C07C43/225 , C07C43/23 , C07C45/42 , C07C46/06 , C07C49/82 , C07C49/84 , C12Q1/001 , C12Q1/004 , G01N27/302 , G01N27/327 , G01N27/3275 , G01N27/4163 , G01N33/5438
摘要： Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.

82. 发明公开

EP3250915A1 SCHUTZBESCHICHTUNG FÜR DAS DIAPHRAGMA ODER DIE OPEN-JUNCTION-ÖFFNUNG DER BEZUGSELEKTRODE EINER POTENTIOMETRISCHEN MESSKETTE 有权
标题翻译：电位计测量链参考电极的隔膜或开路连接开路的保护涂层
公开(公告)号：EP3250915A1
公开(公告)日：2017-12-06
申请号：EP16721633.2
申请日：2016-04-25
申请人： Sartorius Stedim Biotech GmbH
发明人： GRIMM, Christian , WEICHERT, Henry , LUEDERS, Julia
IPC分类号： G01N27/30
CPC分类号： G01N27/302 , G01N27/301 , G01N27/36 , G01N27/401 , G01N27/4035
摘要： The invention relates to a potentiometric measuring chain, comprising an ion-selective electrode, a reference electrode and a reference electrode electrolyte, wherein the reference electrode has a diaphragm or an open-junction opening or a combination thereof, which is provided with a protective coating that is detachable and/or removable when in contact with an aqueous solution. The material of the detachable and/or removable protective coating is preferably selected from: sugars, sugar alcohols, soluble starch, polyvinyl alcohol, microcrystalline cellulose and/or mixtures thereof.

83. 发明授权

EP2753923B1 MEASUREMENT DEVICE WITH SENSOR ARRAY 有权
标题翻译：带传感器阵列的测量装置
公开(公告)号：EP2753923B1
公开(公告)日：2017-11-08
申请号：EP12830358.3
申请日：2012-09-06
申请人： Phase2 Microtechnologies, LLC
发明人： CLARK, William, W. , WAGNER, David, W. , CHO, Sung, Kwon , ZHAO, Yuejun , SYCIARZ, Timothy, J. , FLAHERTY, R., Maxwell , FLAHERTY, J., Christopher
IPC分类号： G01N27/28 , B01L3/00
CPC分类号： G01N27/302 , B01L3/502738 , B01L2200/027 , B01L2200/0673 , B01L2300/0645 , B01L2300/0816 , B01L2300/0829 , B01L2300/087 , B01L2300/1827 , B01L2400/0406 , B01L2400/0427 , B01L2400/049 , B01L2400/0677 , G01N27/28 , G01N27/307 , G01N27/4035 , G01N33/4836
摘要： A system for obtaining a pH measurement includes a disposable probe and a reader. The disposable probe comprises multiple indicating electrodes and at least one reference electrode. The reader is configured to operably engage with the disposable probe and provide pH information of a sample.

84. 发明公开

EP3227671A1 CONTAMINANT DETECTION DEVICE AND METHOD 有权
标题翻译：污染物检测装置和方法
公开(公告)号：EP3227671A1
公开(公告)日：2017-10-11
申请号：EP15865172.9
申请日：2015-12-03
申请人： The Uwm Research Foundation, Inc.
发明人： GUNASEKARAN, Sundaram , CHANG, Woo-Jin , YANG, Jiang , SEENIVASAN, Rajesh
IPC分类号： G01N27/06 , G01N27/07 , G01N33/20 , B41M1/12
CPC分类号： G01N27/4115 , G01N27/301 , G01N27/302 , G01N27/308 , G01N27/333 , G01N27/4148 , G01N27/4167 , G01N27/42 , G01N33/1813
摘要： A device for measuring pH levels and contaminant concentration includes an electrode assembly that is electrically coupled to a control unit. The electrode assembly includes a FLUID first contact electrically coupled to a reference electrode, a second contact electrically coupled to a working electrode, and a third contact electrically coupled to a counter electrode. The working electrode may be modified to include a cysteine functionalized graphene oxide with polypyrrole nanocomposite. In operation, the control unit may apply a complex signal to the working electrode via the second contact in order to adhere and subsequently strip contaminant ions from the fluid sample to the working electrode. During this process, a current may be measured across the reference electrode and the counter electrode to measure contaminant ion concentration. The pH of the fluid sample may also be determined by a current measured across the reference electrode and the counter electrode. In some examples, the pH may be used to calibrate the measured levels of the contaminant ions.
摘要翻译：用于测量pH水平和污染物浓度的装置包括电耦合到控制单元的电极组件。电极组件包括电耦合到参考电极的第一触点，电耦合到工作电极的第二触点以及电耦合到反电极的第三触点。工作电极可以被修饰以包括半胱氨酸官能化石墨烯氧化物和聚吡咯纳米复合材料。在操作中，控制单元可以通过第二触点向工作电极施加复合信号，以便将污染物离子从流体样品附着并随后剥离到工作电极。在此过程中，可以在参比电极和反电极上测量电流，以测量污染物离子浓度。流体样本的pH值也可以通过在参考电极和反电极上测量的电流来确定。在一些示例中，pH可以用于校准污染物离子的测量水平。

85. 发明公开

EP3213360A1 POLYMERIC ELECTRODE FILMS 审中-公开
标题翻译：聚合物电极膜
公开(公告)号：EP3213360A1
公开(公告)日：2017-09-06
申请号：EP15855621.7
申请日：2015-10-29
申请人： Phase2 Microtechnologies, LLC
发明人： BYCHKOVA, Valeriya , SYCIARZ, Timothy, J. , ZHAO, Yuejun , SPEAROT, James, A.
IPC分类号： H01M4/02 , G01N27/28 , G01N27/403
CPC分类号： G01N27/302 , G01N27/301 , G01N27/4167 , H01M4/02 , H01M4/66
摘要： This application describes microelectronic pH sensors that can include indicating electrodes having a substrate, an electrode disposed on the substrate, a reactive layer disposed on a portion of the electrode, and a conductive layer disposed on the reactive material and reference electrodes having similar architecture.
摘要翻译：该申请描述了微电子pH传感器，其可以包括具有衬底，设置在衬底上的电极，设置在电极的一部分上的反应层以及设置在反应材料上的导电层和具有类似结构的参考电极的指示电极。

86. 发明公开

EP3155408A4 SOLID STATE ELECTRODES AND SENSORS 有权
标题翻译： FESTKÖRPERELEKTRODENUND SENSOREN
公开(公告)号：EP3155408A4
公开(公告)日：2017-08-30
申请号：EP15806811
申请日：2015-06-11
申请人： PARKER-HANNIFIN CORP
发明人： LEE ERIC K , VILOZNY BOAZ , ANDREW JAMES
IPC分类号： G01N27/30 , C08J3/075
CPC分类号： C08J3/075 , C08J2329/04 , G01N27/302 , G01N27/4167
摘要： Analyte-insensitive materials comprising polymerizable monomers suitable for use in forming a hydrophilic, cross-linked gel comprising on the surface of a substrate for an electrode.
摘要翻译：包含适合用于形成亲水交联凝胶的可聚合单体的分析物不敏感材料，所述亲水交联凝胶包含在用于电极的基材的表面上。

87. 发明公开

EP2552936A4 SELF-ASSEMBLY OF COATINGS UTILIZING SURFACE CHARGE 有权
标题翻译： SELBSTZUSAMMENSETZUNG VON BESCHICHTUNGEN MITOBERFLÄCHENLADUNG
公开(公告)号：EP2552936A4
公开(公告)日：2016-11-16
申请号：EP11760383
申请日：2011-03-28
申请人： UNIV COLORADO STATE RES FOUND
发明人： PRIETO AMY L , JOHNSON DEREK C , MOSBY JAMES M
IPC分类号： C25D13/02 , C23C18/16 , C25D3/58 , G01N27/30 , G01N27/416 , G01N31/16 , H01M2/16 , H01M4/04 , H01M4/1395 , H01M4/36 , H01M10/052 , H01M10/0562
CPC分类号： C25D13/02 , C23C18/1683 , C25D3/58 , G01N27/302 , G01N27/4167 , G01N31/164 , H01M2/1673 , H01M4/045 , H01M4/0452 , H01M4/1395 , H01M4/366 , H01M10/052 , H01M10/0562 , Y02E60/122
摘要： An apparatus and method for measuring the isoelectric pH for materials deposited on or otherwise affixed onto and in contact with an electrode surface, and a method for utilizing the isoelectric pH to form nanometer thickness, self-assembled layers on the material, are described. Forming such layers utilizing information obtained about the isoelectric pH values of the substrate and the coating is advantageous since the growth of the coating is self-limiting because once the surface charge has been neutralized there is no longer a driving force for the solid electrolyte coating thickness to increase, and uniform coatings without pinhole defects will be produced because a local driving force for assembly will exist if any bare electrode material is exposed to the solution. The present self-assembly procedure, when combined with electrodeposition, may be used to increase the coating thickness. Self-assembly, with or without additional electrodeposition, allows intimate contact between the anode, electrolyte and cathode which is required for successful application to solid-state batteries, as an example.
摘要翻译：描述了用于测量沉积在电极表面上或以其他方式固定到电极表面上或与电极表面接触的材料的等电位pH的装置和方法，以及利用等电位pH在材料上形成纳米厚度的自组装层的方法。利用关于基板和涂层的等电位pH值获得的信息形成这样的层是有利的，因为涂层的生长是自限制的，因为一旦表面电荷被中和，就不再有固体电解质涂层厚度的驱动力增加，并且将产生没有针孔缺陷的均匀涂层，因为如果任何裸电极材料暴露于溶液，则将存在组装的局部驱动力。当与电沉积结合时，本自组装程序可用于增加涂层厚度。作为示例，具有或不具有附加电沉积的自组装允许成功应用于固态电池所需的阳极，电解质和阴极之间的紧密接触。

88. 发明公开

EP2823291A4 ANALYTE SENSING DEVICE 审中-公开
标题翻译： ANALYTERFASSUNGSVORRICHTUNG
公开(公告)号：EP2823291A4
公开(公告)日：2015-12-02
申请号：EP13757037
申请日：2013-03-08
申请人： SENOVA SYSTEMS INC
发明人： LEE ERIC , VU THANG HUY , ANDREW JAMES ALAN , LEONARD LEE
IPC分类号： G01N27/30 , G01N27/416 , G01N33/18
CPC分类号： G01N27/30 , G01N27/302 , G01N27/4167
摘要： Analyte sensing devices suitable for measuring pH or other analytes are provided in a variety of form factors, including a hand-held device.
摘要翻译：适用于测量pH或其他分析物的分析物感测装置以各种形式提供，包括手持装置。

89. 发明公开

EP2944951A1 METHOD FOR IDENTIFYING pH, DEVICE FOR SAME, AND METHOD FOR IDENTIFYING ION CONCENTRATION 有权
标题翻译： VERFAHREN ZUR身份认证EINES PH-WERTES UND VORRICHTUNGDAFÜR
公开(公告)号：EP2944951A1
公开(公告)日：2015-11-18
申请号：EP14737724.6
申请日：2014-01-07
申请人： National University Corporation Toyohashi University of Technology
发明人： DASAI, Fumihiro , SAWADA, Kazuaki , FUTAGAWA, Masato
IPC分类号： G01N27/416 , G01N27/414
CPC分类号： G01N27/302 , G01N27/4145 , G01N27/4165 , G01N27/4167
摘要： The purpose of the present invention is to measure pH of a sample with high accuracy in a pH sensor array, without the use of a glass reference electrode. Each time that a sample is measured, the potential Vrm of the sample is identified, and the identified potential Vrm is used to calculate the pH. The outputs Voi1 and Voi2 of a first element and a second element located near one another in a sensor array are represented as follows. Voi1 = Si1 x pHi1 + Gi1 x Vrm + Cil, Voi2 = Si2 x pHi2 + Gi2 x Vrm + Ci2. Voi is the output of the element, Si and Gi are sensitivity coefficients, and Ci is a constant, these values having been derived in advance. Here, where the potential Vrm is constant, and the elements located near one another are presumed to be at equal pH (pHil = pHi2), the potential Vrm is identified by solving a linear equation with two unknowns.
摘要翻译：本发明的目的是在pH传感器阵列中以高精度测量样品的pH，而不使用玻璃参比电极。每次测量样品时，识别样品的电位Vrm，并使用识别的电位Vrm来计算pH值。传感器阵列中彼此靠近的第一元件和第二元件的输出Vo1和Voi2如下所示。 Voi1 = Si1×pHi1 + Gi1×Vrm + Cil，Voi2 = Si2×pHi2 + Gi2×Vrm + Ci2。 Voi是元素的输出，Si和Gi是灵敏度系数，Ci是常数，这些值是事先得出的。这里，在电位Vrm恒定的情况下，假定彼此相邻的元素处于相同的pH（pHil = pHi2）时，通过求解具有两个未知数的线性方程来识别电位Vrm。

90. 发明公开

EP2939013A1 METHOD AND APPARATUS FOR MONITORING THE QUALITY OF ORE 审中-公开
标题翻译：方法和仪器监测矿石质量
公开(公告)号：EP2939013A1
公开(公告)日：2015-11-04
申请号：EP12866986.8
申请日：2012-12-28
申请人： Outotec (Finland) Oy
发明人： MASHEVSKIY, Gennady Nikolaevich , PETROV, Aleksandr Vladimirovich , ROMANENKO, Sergei Aleksandrovich , KLEMETTI, Matti , ETELAPAA, Mika
IPC分类号： G01N27/416
CPC分类号： G01N27/302 , G01N27/416 , G01N27/4168
摘要： The invention relates to a method and an apparatus for monitoring the quality of an ore delivered to flotation concentration and the state of a slurry prepared from said ore. In the method, two or more working electrodes (6, 7, 8) featuring a cross sensitivity are immersed in the slurry to be monitored and the differences of potentials between each pair of electrodes is measured, whereby no reference electrodes are needed. The working electrodes (6, 7, 8) may comprise an argentite electrode, a platinum electrode and a molybdenum electrode, in which case the following differences of potentials between electrodes are being measured: Δ(Ag-Pt), Δ(Ag-Mo) and Δ(Pt-Mo).

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