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72. 发明公开

EP0690073A1 Saturated, aminated, alkoxylated polybutadienes 失效
标题翻译： Gesättigte，aminierte，烷氧基聚丁二烯
公开(公告)号：EP0690073A1
公开(公告)日：1996-01-03
申请号：EP94304659.9
申请日：1994-06-27
申请人： HUNTSMAN CORPORATION
发明人： Knifton, John Frederick , Cuscurida, Michael
IPC分类号： C08C19/38
CPC分类号： C08C19/38 , C07C213/06 , C07C217/10
摘要： Saturated, aminated alkoxylated polymers having a high degree of maintain and saturation can be obtained by reductive amination of an alkyoxylated liquid polymer obtained by alkoxylating a hydroxyl-terminated polybutadiene (HTPB) with one or more alkylene oxides having at least three carbon atoms to provide secondary terminal hydroxyl groups, by contacting the alkoxylated liquid polymer is contacted with hydrogen and ammonia in the presence of a catalyst whose active components are nickel oxide, copper oxide, chromium oxide and molybdenum oxide, the molar ratio of hydrogen to ammonia to secondary hydroxyl groups on the alkoxylated liquid polymer being at least 50 : at least 10:1.
Preferred products include saturated, aminated alkoxylated polymers of the formula:

wherein each R is independently alkyl of 1 to 4 carbon atoms;
each n is independently from 1 to 100; and
x, y and z are numbers,
the number average molecular weight of the hydrocarbon backbone being from 200 to 5000.
摘要翻译：具有高维持度和饱和度的饱和的胺化的烷氧基化聚合物可以通过将具有一个或多个具有至少三个碳原子的一个或多个环氧烷烷氧基化羟基封端的聚丁二烯（HTPB）获得的烷氧基化液体聚合物的还原胺化得到二次末端羟基，通过使烷氧基化液体聚合物与氢和氨在活性组分为氧化镍，氧化铜，氧化铬和氧化钼的催化剂存在下接触，氢与氨与仲羟基的摩尔比在所述烷氧基化液体聚合物为至少50：至少10:1。优选的产物包括下式的饱和的胺化烷氧基化聚合物：其中每个R独立地为1至4个碳原子的烷基; 每个n独立地为1至100; x，y和z为数，烃骨架的数均分子量为200〜5000。

73. 发明授权

EP0570443B1 AMINOALCOHOLS USEFUL AS OPTICAL RESOLVING AGENTS 失效
标题翻译：氨基醇作为光学分辨率试剂。
公开(公告)号：EP0570443B1
公开(公告)日：1995-11-29
申请号：EP92904156.4
申请日：1992-02-07
申请人： SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES
发明人： BROWN, Eric Faculté des Sciences , TOUET, Jöel Faculté des Sciences , LE GOFF, Jean-Pierre
IPC分类号： C07C217/10
CPC分类号： C07C231/20 , C07C217/10
摘要： A compound of formula (I), or a salt or solvate thereof, in which R1 and R2 each independently represents hydrogen, alkyl, optionally substituted aryl or optionally substituted aralkyl; R3 represents alkyl, optionally substituted aryl or optionally substituted aralkyl and R4 represents alkyl or optionally substituted aryl; a process for preparing such compounds and the use of such compounds for resolving certain racemates.

74. 发明公开

EP0642302A4 PLANT BIOREGULATORY COMPOSITION AND METHOD USING (BENZYL SUBSTITUTED) TRIALKYLAMINE ETHER COMPOUNDS. 失效
标题翻译：生物调节组合物对植物和使用（苄基 - 取代的）三烷基胺醚化合物方法。
公开(公告)号：EP0642302A4
公开(公告)日：1994-12-27
申请号：EP93908558
申请日：1993-03-24
申请人： TROPICANA PROD INC , US AGRICULTURE
发明人： YOKOYAMA HENRY , KEITHLY JAMES H , GAUSMAN HAROLD W
IPC分类号： A01N33/08 , C07C217/10 , C07C217/20 , C07C323/25 , A01N33/04 , A01N33/10 , C07C323/26
CPC分类号： C07C217/20 , A01N33/08 , C07C217/10 , A01N2300/00
摘要： The present invention is directed to a new matter of composition in the form of chemical compounds and to methods for enhancing plant growth and the properties exhibited by plants treated with the compounds in accordance with this method. In particular, application of the compounds results in an increase in sugar content, essential oils and proteins along with an increase in total plant biomass. Fruits harvested from treated plants exhibit an accelerated biochemical and structural maturity. Citrus fruits typically show a reduced peel thickness and exhibit significant improvements in vitamin C, carotenoid, and essential oil contents. The methods of the present invention produce balanced improvements in the structural, biochemical, and sensory quality of Citrus fruits. Mixtures of the compounds may be applied. Certain mixtures are known to have synergistic effects. The compounds or mixtures thereof may also be applied in vitro.

75. 发明公开

EP0587194A1 2-(Heterocycloalkoxy)-1-(subst.-phenyl)-ethanol derivatives as cerebral function improving agents 失效
标题翻译： 2-（杂环烷氧基）-1-（对苯基） - 乙醇衍生物，大肠杆菌功能。
公开(公告)号：EP0587194A1
公开(公告)日：1994-03-16
申请号：EP93115719.2
申请日：1990-02-13
申请人： TOYAMA CHEMICAL CO., LTD.
发明人： Ono, Satoshi , Yamafuji, Tetsuo , Chaki, Hisaaki , Maekawa, Mutsuko , Todo, Yozo , Narita, Hirokazu
IPC分类号： C07D207/08 , C07D207/14 , C07D207/26 , C07D207/28 , C07D211/22 , C07D211/42 , C07D211/46 , C07D211/70 , C07D213/30 , C07D217/04 , C07D233/54 , C07D241/04 , C07D259/00 , C07D265/30 , C07D279/12 , C07D295/08 , C07D453/02 , A61K31/445 , A61K31/415
CPC分类号： C07C271/46 , C07C217/10 , C07C217/76 , C07C229/12 , C07C233/18 , C07C271/44 , C07C271/58 , C07C311/08 , C07C311/21 , C07C317/22 , C07C323/19 , C07C2601/02 , C07C2601/08 , C07C2601/10 , C07C2602/08 , C07C2602/10 , C07D207/08 , C07D207/14 , C07D207/16 , C07D207/22 , C07D207/27 , C07D207/28 , C07D209/08 , C07D209/12 , C07D209/32 , C07D209/34 , C07D211/14 , C07D211/22 , C07D211/32 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/70 , C07D211/74 , C07D213/26 , C07D213/30 , C07D213/61 , C07D213/64 , C07D213/74 , C07D213/82 , C07D215/14 , C07D215/227 , C07D217/04 , C07D231/12 , C07D233/56 , C07D233/64 , C07D235/06 , C07D239/42 , C07D241/04 , C07D241/42 , C07D249/08 , C07D259/00 , C07D265/30 , C07D277/24 , C07D277/62 , C07D277/64 , C07D279/12 , C07D295/088 , C07D307/42 , C07D307/79 , C07D307/80 , C07D309/12 , C07D317/54 , C07D319/18 , C07D333/16 , C07D333/28 , C07D333/44 , C07D333/54 , C07D333/56 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D453/02
摘要： This invention relates to a 1,2-ethanediol derivative of formula I where R⁶ represents a substituted or unsubstituted nitrogen-containing heterocyclic group, the nitrogen-containing heterocyclic group

and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebrovascular dementia, senile dementia, Alzheimer's dementia, sequelae of ischemic encephalopathy and cerebral apoplexy.
摘要翻译： 1-苯基-2- substd。氧乙醇衍生物。式（CH2）CHR3-O-（CR4R5）n-R6（Ⅰ）及其盐是新的; n为0-6; R 1是苯基（选自（i）卤素，（ii）NQ 1 Q 2，（iii）烷基，丙烯酰基，芳烷基，烷氧基，芳氧基，芳氧基，氨基甲酰氧基，烷硫基，烯基，烯氧基，芳烷硫基，芳烷基磺酰基，芳基磺酰基，烷基磺酰基氨基，或（iv）被保护的氨基，选择性保护的羟基，NO 2，氧代或低级亚烷基二氧基）; R2是H，烷基或羟基保护基; R3-R5是H或烷基; R6是氨，NQ1Q2或Het; Het是N-键杂环gp。例如吡咯基，吡咯烷基，哌啶基，哌嗪基，咪唑基，吡唑基，吡啶基，四氢吡啶基，嘧啶基，吗啉基，硫代吗啉基，喹啉基，喹嗪基，四氢喹啉基等。 Q1，Q2是H，opt。保护的OH，烷基（选择性保护的OH或选择性保护的COOH），环烷基，芳基，低级酰基，芳烷基，Het1，Het1-O-CO-（被氧代选择），金刚烷基，烷基磺酰基或芳基磺酰基; Het1是N-contg。杂环类似于Het; 或例如呋喃基，噻吩基，苯并噻吩基，吡喃基，异苯并呋喃基，咪唑并（2,3-a）吡啶基，苯并（b）哌嗪基，色烯基，异噻唑基，异恶唑基，恶二唑基，哒嗪基，异吲哚基或异喹啉基等。所有烷基和烯基部分较低，即高达6C; 附带条件。

76. 发明公开

EP0587193A1 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same 失效
标题翻译： 1,2- Ethandiolderivate和它们的盐，它们的制备方法和含有它们的组合物的方法，脑功能改善剂。
公开(公告)号：EP0587193A1
公开(公告)日：1994-03-16
申请号：EP93115717.6
申请日：1990-02-13
申请人： TOYAMA CHEMICAL CO., LTD.
发明人： Ono, Satoshi , Yamafuji, Tetsuo , Chaki, Hisaaki , Maekawa, Mutsuko , Todo, Yozo , Narita, Hirokazu
IPC分类号： C07C217/10 , A61K31/13 , A61K31/33 , A61K31/21 , C07D295/088 , C07D207/27 , C07C323/19 , C07D317/54 , C07D211/20 , C07D333/16 , C07D207/08
CPC分类号： C07C271/46 , C07C217/10 , C07C217/76 , C07C229/12 , C07C233/18 , C07C271/44 , C07C271/58 , C07C311/08 , C07C311/21 , C07C317/22 , C07C323/19 , C07C2601/02 , C07C2601/08 , C07C2601/10 , C07C2602/08 , C07C2602/10 , C07D207/08 , C07D207/14 , C07D207/16 , C07D207/22 , C07D207/27 , C07D207/28 , C07D209/08 , C07D209/12 , C07D209/32 , C07D209/34 , C07D211/14 , C07D211/22 , C07D211/32 , C07D211/42 , C07D211/44 , C07D211/46 , C07D211/70 , C07D211/74 , C07D213/26 , C07D213/30 , C07D213/61 , C07D213/64 , C07D213/74 , C07D213/82 , C07D215/14 , C07D215/227 , C07D217/04 , C07D231/12 , C07D233/56 , C07D233/64 , C07D235/06 , C07D239/42 , C07D241/04 , C07D241/42 , C07D249/08 , C07D259/00 , C07D265/30 , C07D277/24 , C07D277/62 , C07D277/64 , C07D279/12 , C07D295/088 , C07D307/42 , C07D307/79 , C07D307/80 , C07D309/12 , C07D317/54 , C07D319/18 , C07D333/16 , C07D333/28 , C07D333/44 , C07D333/54 , C07D333/56 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D453/02
摘要： This invention relates to a 1,2-ethanediol derivative and a salt thereof, a process for producing the same, and a cerebral function-improving agent comprising the same. The cerebral function-improving agent of this invention is useful for treating cerebrovascular dementia, senile dementia, Alzheimer's dementia, sequelae of ischemic encephalopathy and cerebral apoplexy.

77. 发明授权

EP0365093B1 Muscarinic receptor antagonists 失效
标题翻译：肌肉受体拮抗剂
公开(公告)号：EP0365093B1
公开(公告)日：1992-09-02
申请号：EP89202611.3
申请日：1989-10-16
申请人： PFIZER INC.
发明人： Alker, David , Cross, Peter Edward , Bass, Robert John
IPC分类号： C07C217/60 , A61K31/135 , C07C217/52 , C07D317/58 , C07D319/18 , C07D307/79 , C07C217/10 , C07C311/37 , C07C311/08 , C07D333/20 , C07C237/30
CPC分类号： C07D307/79 , C07C217/10 , C07C217/52 , C07C217/56 , C07C225/16 , C07C229/38 , C07C237/32 , C07C255/58 , C07C311/05 , C07C311/08 , C07C311/37 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07C2603/32 , C07D317/58 , C07D319/18 , C07D333/20 , C07D337/12

78. 发明公开

EP0422889A2 Phenethanolamine compounds 失效
标题翻译：苯乙醇胺Verbindungen。
公开(公告)号：EP0422889A2
公开(公告)日：1991-04-17
申请号：EP90311043.5
申请日：1990-10-09
申请人： GLAXO GROUP LIMITED
发明人： Evans, Brian
IPC分类号： C07C217/10
CPC分类号： C07C217/10
摘要： The present invention provides the compound (R)-(-)-4-hydroxy-α¹-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol or physiologically acceptable salts thereof, processes for its preparation, pharmaceutical formulations containing it, and its use in medicine.
摘要翻译：本发明提供化合物（R） - （ - ） - 4-羟基-α1 - [[[6-（4-苯基丁氧基）己基]氨基]甲基] -1,3-苯二甲醇或其生理上可接受的盐，其制备方法，含有它的药物制剂及其在医学中的用途。

79. 发明公开

EP3375774A1 PHENALEN-1-ON-HALTIGE PHOTOSENSIBILISATORZUSAMMENSETZUNG, PHENALEN-1-ON-VERBINDUNGEN SOWIE DEREN VERWENDUNG 审中-实审
公开(公告)号：EP3375774A1
公开(公告)日：2018-09-19
申请号：EP17161718.6
申请日：2017-03-17
申请人： Trioptotec GmbH
发明人： SPÄTH, Andreas , EICHNER, Anja
IPC分类号： C07D213/30 , C07C49/755 , C09D5/14 , C08K5/08 , A61L2/08 , C07C69/54 , C07C69/76 , C07C217/12 , C07C225/18 , C07C271/16 , C07C271/20 , C07C233/31 , C07C233/38 , C07D303/22 , C07F7/04 , C07F7/18 , C09D133/14 , C09D175/04 , C09D183/10
CPC分类号： C07D213/30 , C07C49/737 , C07C49/755 , C07C69/54 , C07C69/76 , C07C217/08 , C07C217/10 , C07C217/12 , C07C225/18 , C07C233/31 , C07C233/38 , C07C271/16 , C07C271/20 , C07C317/22 , C07C2601/14 , C07C2603/28 , C07D303/22 , C07F7/045 , C07F7/0834 , C07F7/1804
摘要： Die vorliegende Erfindung betrifft eine Photosensibilisatorzusammensetzung, umfassend
(a) wenigstens eine Phenalen-1-on-Verbindung der allgemeinen Formel (1)

worin wenigstens einer der Reste R1 bis R7 ein organischer Rest W1 ist, wobei der organische Rest W1 jeweils unabhängig voneinander einen Rest der allgemeinen Formel (2) bis (6) darstellt:
* - [(C(D)(E)) d - B] a - (C(D)(E)) m - X (2)
* - A - [(C(D)(E)) d - B] c - (C(D)(E)) m - X (3)
* - (C(D)(E)) d - Ar - (C(D)(E)) n - X (4)
* - [(C(D)(E)) d - B] b - (C(D)(E)) g - Ar - (C(D)(E)) n - X (5)
* - A - [(C(D)(E)) d - B] f - (C(D)(E)) g - Ar - (C(D)(E)) n - X (6)
wobei der Rest X jeweils unabhängig voneinander eine (im Hinblick auf (b)) reaktive funktionelle Gruppe ist, und
(b) wenigstens eine polymere Komponente und/oder deren Vorläufer,
einen Gegenstand, umfassend eine diese Photosensibilisatorzusammensetzung enthaltende, ausgehärtete Polymerzusammensetzung, und
deren Verwendung zur, vorzugsweise photodynamischen, Inaktivierung von Mikroorganismen (insbesondere zur photodynamischen Oberflächenreinigung und/oder Oberflächenbeschichtung eines Gegenstandes oder Raumes und/oder zur Oberflächenbeschichtung von Gegenständen, wie z.B. Medizinprodukten, Lebensmittelverpackungen, Verpackungsfolien, Textilien, Baustoffen, Spielzeugen, elektronische Geräten, Möbeln oder Hygieneartikeln).

80. 发明授权

EP1937626B1 Process and intermediates for the preparation of Salmeterol 失效转让
标题翻译：方法和中间体为沙美特罗的制备
公开(公告)号：EP1937626B1
公开(公告)日：2016-02-17
申请号：EP06794800.0
申请日：2006-10-17
申请人： Generics [UK] Limited
发明人： GORE, Vinayak, G. , GAIKWAD, Avinash, C. , GADAKAR, M. , SHUKLA, V., K.
IPC分类号： C07C41/16 , C07C43/174 , C07C213/08 , C07C217/10
CPC分类号： C07C217/10 , C07C41/16 , C07C43/174 , C07C213/08 , Y02P20/55

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