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71. 发明授权

EP2691992B1 GRAPHENE-BASED MULTI-JUNCTIONS FLEXIBLE SOLAR CELL 有权
标题翻译：与多个终端基于图形的柔性太阳能电池
公开(公告)号：EP2691992B1
公开(公告)日：2016-05-04
申请号：EP12763019.2
申请日：2012-03-13
申请人： California Institute of Technology
发明人： ARIA, Adrianus, I. , GHARIB, Morteza
IPC分类号： H01L31/0687 , H01L31/042 , H01L31/18 , H01L31/078 , B82Y30/00 , H01L31/043
CPC分类号： H01L31/1804 , B82Y30/00 , H01L31/043 , H01L31/0687 , H01L31/1896 , Y02E10/544 , Y02E10/547 , Y02P70/521

72. 发明公开

EP2986997A1 LIFE DETECTING RADARS 无效
标题翻译： LEBENSERKENNUNGSRADARE
公开(公告)号：EP2986997A1
公开(公告)日：2016-02-24
申请号：EP14785477.2
申请日：2014-04-18
申请人： California Institute of Technology
发明人： LUX, James, Paul , CABLE, Vaughn, P. , HAQUE, Salman, Mohammed , MCKEE, Michael, Ray , GHAEMI, Hirad , KALANTAR, OHANIAN, Richard
IPC分类号： G01S7/40 , G01R13/00
CPC分类号： A61B5/0022 , A61B5/024 , A61B5/0507 , A61B5/0816 , A61B5/1126 , A61B5/117 , A61B5/7257 , A62B33/00 , G01S7/003 , G01S13/347 , G01S13/56 , G01S13/88 , G06F19/00 , G16H40/67
摘要： Systems and methods for detecting biometrics using a life detecting radar are disclosed. Life detecting radars can include transmit antennas configured to transmit continuous microwave (“CW”) radio signals that reflect back upon making contact with various objects. The signal can be systematically varied in frequency to provide a signal that is essentially continuous with short gaps between transmissions at different frequencies. The reflected return signals are received by one or more receive antennas and processed to detect one or more targets. The received signal can include a static (i.e. constant phase) signal corresponding to reflections from objects that do not move. The received signal can also include a phase varying signal that corresponds to reflections from a living target having measurable biometrics including (but not limited to) breathing patterns and heartbeats. Clutter can be removed and the remaining portions of the received signal are analyzed for target detection.
摘要翻译：公开了使用寿命检测雷达来检测生物识别的系统和方法。生命检测雷达可以包括配置成在与各种物体接触时反射回发射的连续微波（“CW”）无线电信号的发射天线。该信号可以在频率上系统地变化，以提供基本上与不同频率的传输之间的短间隙连续的信号。反射的返回信号由一个或多个接收天线接收并被处理以检测一个或多个目标。所接收的信号可以包括对应于不移动的物体的反射的静态（即，恒定相位）信号。所接收的信号还可以包括对应于来自具有可测量生物特征的活的目标的反射的相变信号，包括（但不限于）呼吸模式和心跳。可以去除杂波，并分析接收信号的剩余部分以进行目标检测。

73. 发明公开

EP2981858A1 NANOSCALE PLASMONIC FIELD-EFFECT MODULATOR 有权转让
标题翻译： NANOSKALIGER PLASMONENFELDEFFEKTMODULATOR
公开(公告)号：EP2981858A1
公开(公告)日：2016-02-10
申请号：EP14778727.9
申请日：2014-04-04
申请人： California Institute of Technology
发明人： LEE, Ho, Wai , BURGOS, Stanley , PAPADAKIS, Georgia , ATWATER, Harry A.
IPC分类号： G02B6/122 , G02B6/26
CPC分类号： G02B5/008 , B82Y20/00 , G02B6/1226 , G02F1/011 , G02F1/025 , G02F1/0356 , G02F2001/0151 , G02F2201/12 , G02F2203/10 , G02F2203/15 , Y10S977/932
摘要： A plasmonic device having a transparent conducting oxide (TCO) waveguide and a tunable voltage applied across the TCO and a metal layer for modulating an input optical signal.
摘要翻译：具有透明导电氧化物（TCO）波导和跨TCO施加的可调谐电压的等离子体元件和用于调制输入光信号的金属层。

74. 发明公开

EP2961788A1 NANOPARTICLES STABILIZED WITH NITROPHENYLBORONIC ACID COMPOSITIONS 有权转让
标题翻译：用硝基苯甲酸组合物稳定的纳米颗粒
公开(公告)号：EP2961788A1
公开(公告)日：2016-01-06
申请号：EP13876452.7
申请日：2013-03-01
申请人： California Institute of Technology
发明人： DAVIS, Mark, E. , HAN, Han
IPC分类号： C08G79/08
CPC分类号： C08G79/08 , A61K9/5146 , A61K47/34 , A61K47/36 , A61K47/68 , A61K47/6855 , A61K47/6935 , C08G73/028 , C12N15/88
摘要： Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle. Targeted versions of the described nanoparticles are also described, as are related compositions, methods and systems.
摘要翻译：本文描述了载体纳米粒子，其包含含有与含有硼酸的聚合物偶联的多元醇的聚合物的聚合物载体，其被配置为将含有硼酸的聚合物呈递至纳米粒子外部的环境。还描述了所描述的纳米颗粒的靶向形式，以及相关的组合物，方法和系统。

75. 发明授权

EP1088220B1 Polymer/plasticizer based sensor array 有权
标题翻译：聚合物/增塑剂基传感器阵列
公开(公告)号：EP1088220B1
公开(公告)日：2015-11-04
申请号：EP99930562.6
申请日：1999-06-22
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人： GRUBBS, Robert, , MATZGER, Adam J., , LEWIS, Nathan S.,
IPC分类号： G01N27/00
CPC分类号： G01N27/126 , G01N33/0031

76. 发明公开

EP2880184A1 MULTIPLEXING AND QUANTIFICATION IN PCR WITH REDUCED HARDWARE AND REQUIREMENTS 有权转让
标题翻译：复用和量化与PCR技术降低了硬件并降低要求
公开(公告)号：EP2880184A1
公开(公告)日：2015-06-10
申请号：EP13824744.0
申请日：2013-08-02
申请人： California Institute of Technology
发明人： MALIK, Imran, R. , MADERO, Xiomara, L. , GARCIA, Erika, F. , SHAH, Sheel, M. , SCHERER, Axel
IPC分类号： C12Q1/68 , C12M1/38 , C12N15/11
CPC分类号： G01N21/6486 , C12Q1/6851 , C12Q2537/143 , C12Q2537/165 , C12Q2565/629
摘要： Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.

77. 发明公开

EP2828870A1 MICRO -AND NANOSCALE CAPACITORS THAT INCORPORATE AN ARRAY OF CONDUCTIVE ELEMENTS HAVING ELONGATED BODIES 无效
标题翻译： MICRO和纳米电容器成型官员组成的数组已扩展BODIES
公开(公告)号：EP2828870A1
公开(公告)日：2015-01-28
申请号：EP13764392.0
申请日：2013-03-14
申请人： California Institute of Technology
发明人： MANOHARA, Harish , DEL CASTILLO, Linda, Y. , MOJARRADI, Mohammed
IPC分类号： H01G4/005
CPC分类号： H01G4/30 , B82Y10/00 , H01G4/01 , H01G4/1209 , H01G4/14 , H01G4/232 , H01G4/242 , H01G4/33 , H01G4/38 , H01L28/60 , H01L28/86 , H01L28/90
摘要： Systems and methods in accordance with embodiments of the invention implement micro- and nanoscale capacitors that incorporate a conductive element that conforms to the shape of an array elongated bodies. In one embodiment, a capacitor that incorporates a conductive element that conforms to the shape of an array of elongated bodies includes: a first conductive element that conforms to the shape of an array of elongated bodies; a second conductive element that conforms to the shape of an array of elongated bodies; and a dielectric material disposed in between the first conductive element and the second conductive element, and thereby physically separates them.
摘要翻译：与本发明的实施例的系统和在雅舞蹈方法来实现微和纳米电容器没有掺入的导电元件做个符合阵列细长体的形状。在一个，电容器实施方式做了结合导电元件确实符合细长体的阵列的形状，包括：第一导电元件确实符合细长体的阵列的形状; 导电做了第二元件符合细长体阵列的形状; 和电介质材料设置在所述第一元件和所述第二导电元件的导电之间，从而物理上分开它们。

78. 发明公开

EP2806025A1 Use of zinc finger nucleases to stimulate gene targeting 审中-公开
标题翻译： Verwendung von Zinkfingernukleasen zur Stimulierung von Gentargeting
公开(公告)号：EP2806025A1
公开(公告)日：2014-11-26
申请号：EP14164933.5
申请日：2003-09-05
申请人： California Institute of Technology
发明人： Baltimore, David , Porteus, Matthew
IPC分类号： C12N9/22 , C12N15/90 , C12N15/55 , C12N15/62 , C12N5/10 , A61K48/00
CPC分类号： C12N15/907 , A61K48/00 , C07K2319/00 , C07K2319/09 , C07K2319/43 , C07K2319/81 , C12N9/22 , C12N2800/80 , C12N2830/00 , C12N2830/002 , C12N2830/15 , C12N2830/48 , C12N2830/60 , C12N2830/90 , C12N2840/203
摘要： The present invention relates to a vector comprising (a) a nucleic acid encoding a chimeric nuclease, wherein the chimeric nuclease comprises: (i) a DNA binding domain comprising a zinc finger domain; (ii) a Fok I cleavage domain; (iii) a nuclear localization signal (NLS); and (b) a nucleic acid comprising a repair substrate that comprises: (i) a nucleic acid sequence that is substantially identical to a region flanking a target sequence in chromosomal DNA; and (ii) a nucleic acid sequence which replaces the target sequence upon recombination between the repair substrate and the target sequence.
摘要翻译：本发明涉及包含（a）编码嵌合核酸酶的核酸的载体，其中所述嵌合核酸酶包含：（i）包含锌指结构域的DNA结合结构域; （ii）Fok I切割结构域; （iii）核定位信号（NLS）; 和（b）包含修复底物的核酸，其包含：（i）与染色体DNA中的靶序列侧翼的区域基本相同的核酸序列; 和（ii）在修复底物和靶序列之间重组时替代靶序列的核酸序列。

79. 发明公开

EP2793019A2 Integrated capacitive microfluidic sensors method and apparatus 无效
标题翻译： Integrierte kapazitive Mikrofluidsensoren，Verfahren und Vorrichtung
公开(公告)号：EP2793019A2
公开(公告)日：2014-10-22
申请号：EP14168977.8
申请日：2004-03-17
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人： Xie, Jun , Shih, Jason , Tai, Yu-Chong
IPC分类号： G01N27/22
CPC分类号： G01N27/226 , B81B7/02 , B81B2201/0292 , B81B2201/058 , G01L9/0042 , G01L9/0072
摘要： A microfluidic device and method for capacitive sensing. The device includes a fluid channel including an inlet at a first end and an outlet at a second end, a cavity region coupled to the fluid channel, and a Parylene membrane coupled between the fluid channel and the cavity region. Additionally, the device includes a first capacitor electrode coupled to the membrane, a second capacitor electrode coupled to the cavity region and physically separated from the first capacitor electrode by at least the cavity region, and an electrical power source coupled between the first capacitor electrode and the second capacitor electrode and causing an electric field at least within the cavity region.
摘要翻译：用于电容感测的微流体装置和方法。该装置包括流体通道，其包括在第一端处的入口和在第二端处的出口，耦合到流体通道的空腔区域以及耦合在流体通道和腔区域之间的聚对二甲苯膜。另外，该装置包括耦合到膜的第一电容器电极，耦合到空腔区域的第二电容器电极，并且至少通过空腔区域与第一电容器电极物理分离;以及电源，耦合在第一电容器电极和所述第二电容器电极至少在所述腔区域内产生电场。

80. 发明授权

EP2056708B1 MICROFABRICATED IMPLANTABLE WIRELESS PRESSURE SENSOR FOR USE IN BIOMEDICAL APPLICATIONS AND PRESSURE MEASUREMENT AND SENSOR IMPLANTATION METHODS 有权
标题翻译：微制造可植入的无线压力传感器，其用于使用在生物医学应用和传感器的压力测量植入手术
公开(公告)号：EP2056708B1
公开(公告)日：2014-07-16
申请号：EP07814555.4
申请日：2007-08-29
申请人： California Institute of Technology
发明人： TAI, Yu-Chong Caltech Electrical Engineering , CHEN, Po-Jui , RODGER, Damien C. , HUMAYUN, Mark S.
IPC分类号： A61B3/16 , A61B13/00 , G01L9/00 , A61B5/0215 , A61B5/03
CPC分类号： A61B3/16 , A61B5/0031 , A61B5/0215 , A61B5/03 , G01L9/0072

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