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61. 发明公开

EP1996266A2 NASAL DELIVERY 审中-公开
公开(公告)号：EP1996266A2
公开(公告)日：2008-12-03
申请号：EP07734890.2
申请日：2007-03-06
申请人： Optinose AS
发明人： DJUPESLAND, Dr Per Gisle
IPC分类号： A61M15/08 , A61F5/08
CPC分类号： A61M15/08 , A61M11/00 , A61M15/0021 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M15/085 , A61M31/00 , A61M2202/064
摘要： A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit (20, 24) including a nosepiece (17) for fitting to a nostril of a subject and a nozzle (45) through which substance is in use delivered, preferably substantially axially to a longitudinal axis of the nosepiece, to the respective nasai cavity, wherein at least a tip element of the nosepiece has, at least in one configuration, an elongate lateral section which has a longer dimension in a first, sagittal direction than a second direction orthogonal to the sagittal direction, such that, when the nosepiece is inserted in the nasal' cavity of the subject, the longer dimension of the nosepiece acts to engage lower and upper surfaces of the nasal cavity, preferably at the nasa valve, and expand the same in the sagittal plane; and a delivery unit (43, 49, 51) for delivering substance through the nozzle of the nosepiece.
摘要翻译： 1。一种用于将物质递送至受试者的鼻腔的鼻递送装置和方法，所述递送装置包括：鼻部单元（20,24），所述鼻部单元包括用于配合至受治疗者鼻孔的鼻部（17）和喷嘴（45）），优选地基本上轴向地延伸至鼻甲的纵向轴线，其中至少在一种构造中，鼻甲的至少一个尖端元件具有细长的横向部分，该细长的横向部分具有在垂直于矢状方向的第二方向上的第一弧矢方向上具有较长的尺寸，使得当将鼻用件插入受治疗者的鼻腔时，鼻用件的较长尺寸用于接合鼻子的下表面和上表面鼻腔，优选在美国国家航空航天局阀门，并在矢状面扩展; 以及用于通过喷嘴的喷嘴输送物质的输送单元（43,49,51）。

62. 发明公开

EP1988954A2 DELIVERY DEVICE AND METHOD 审中-公开
标题翻译：供应装置及方法
公开(公告)号：EP1988954A2
公开(公告)日：2008-11-12
申请号：EP07705201.7
申请日：2007-02-14
申请人： Optinose AS
发明人： DJUPESLAND, Per, Gisle , SHELDRAKE, Colin, David , HAFNER, Roderick, Peter
IPC分类号： A61M15/08
CPC分类号： A61M15/0098 , A61M11/00 , A61M15/0021 , A61M15/009 , A61M15/0091 , A61M15/08 , A61M2210/0681
摘要： A nasal delivery device for and method of delivering substance to the middle meatus in a nasal cavity of a subject in the treatment of a condition, in particular an inflammatory or infectious condition, thereof, the delivery device comprising: a nosepiece unit (17) including a nosepiece (20) for fitting to a nostril of a subject and a nozzle (25) through which substance is in use delivered to the respective nasal cavity; and a delivery unit (29) for delivering substance through the nozzle of the nosepiece; wherein the delivery device is configured to provide for deposition of a significant fraction of the delivered dose on, around and in the vicinity of the middle meatus.

63. 发明授权

EP3220989B1 INTRANASAL ADMINISTRATION 有权转让
公开(公告)号：EP3220989B1
公开(公告)日：2020-06-24
申请号：EP15798061.6
申请日：2015-11-19
申请人： Optinose AS
发明人： DJUPESLAND, Per Gisle , SHELDRAKE, Colin David
IPC分类号： A61M15/08 , A61M15/00

64. 发明公开

EP3220988A1 INTRANASAL ADMINISTRATION 无效转让
公开(公告)号：EP3220988A1
公开(公告)日：2017-09-27
申请号：EP15798058.2
申请日：2015-11-19
申请人： Optinose AS
发明人： DJUPESLAND, Per Gisle , MAHMOUD, Ramy A. , ANDREASSEN, Ole A. , WESTLYE, Lars T. , QUINTANA, Daniel S. , SMERUD, Knut T. , SHELDRAKE, Colin David
IPC分类号： A61M15/08 , A61M15/00
CPC分类号： A61M15/08 , A61K9/0043 , A61K38/08 , A61K38/11 , A61M11/00 , A61M15/0013 , A61M15/0021 , A61M15/009 , A61M15/0098 , A61M29/00 , A61M31/00 , A61M2202/04 , A61M2202/064 , A61M2210/0618
摘要： A delivery device for and method of modulating a condition relating to social cognition and/or behaviour in a human subject using oxytocin, non-peptide agonists thereof and/or antagonists thereof, comprising : providing a nosepiece to a first nasal cavity of the subject; and providing a supply unit for administering less than 241 U of oxytocin, non-peptide agonists thereof and/or antagonists thereof through the nosepiece to an upper region posterior of the nasal valve which is innervated by the trigeminal nerve.

65. 发明授权

EP2817052B1 NASAL DELIVERY DEVICES 有权转让
公开(公告)号：EP2817052B1
公开(公告)日：2017-09-13
申请号：EP13711300.7
申请日：2013-02-25
申请人： Optinose AS
发明人： DJUPESLAND, Per Gisle , LECLERC, Michael , MAHMOUD, Ramy A , SIWINSKI, Shane , GORDON, Joseph , FISK, Justin
IPC分类号： A61M15/08 , A61M15/00
CPC分类号： A61M15/08 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/009 , A61M15/0098 , A61M2210/0618

66. 发明授权

EP2460554B1 Nasal delivery device 有权转让
标题翻译： Nasale Abgabevorrichtungen
公开(公告)号：EP2460554B1
公开(公告)日：2016-06-29
申请号：EP12001127.5
申请日：2007-11-28
申请人： Optinose AS
发明人： Djupesland, Per, Gisle, Dr. , Sheldrake, Colin, David, Dr. , Smith, Simon , Striebig, Rachel , Pidgeon, Andy , St. Quintin, Tom
IPC分类号： A61M16/10 , A61M15/08 , A61M15/00
CPC分类号： A61M15/08 , A61M15/0018 , A61M15/0021 , A61M15/0026 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0043 , A61M15/0081 , A61M15/0098 , A61M16/1045 , A61M2202/064 , A61M2205/0222 , A61M2210/0618 , A61M2210/0625

67. 发明公开

EP2978482A2 NASAL ADMINISTRATION 有权转让
标题翻译： NASALE VERABREICHUNG
公开(公告)号：EP2978482A2
公开(公告)日：2016-02-03
申请号：EP14721008.2
申请日：2014-03-26
申请人： Optinose AS
发明人： DJUPESLAND, Per Gisle , MAHMOUD, Ramy, A. , MESSINA, John
IPC分类号： A61M15/08
CPC分类号： A61M15/08 , A61K9/0043 , A61K9/0075 , A61K31/4045 , A61K31/56 , A61K33/00 , A61M5/14 , A61M11/00 , A61M11/006 , A61M15/0021 , A61M15/0098 , A61M16/0057 , A61M16/0666 , A61M16/105 , A61M16/1075 , A61M16/12 , A61M16/14 , A61M16/20 , A61M2202/0225 , A61M2202/0468 , A61M2202/064 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334

68. 发明授权

EP1799290B1 NASAL DELIVERY DEVICES 有权转让
标题翻译： NASALE ABGABEVORRICHTUNGEN
公开(公告)号：EP1799290B1
公开(公告)日：2015-08-12
申请号：EP05789130.1
申请日：2005-09-15
申请人： Optinose AS
发明人： DJUPESLAND, Per Gisle, Optinose AS , HAFNER, Roderick Peter, Optinose UK Ltd , SHELDRAKE, Colin David, Optinose UK Ltd
IPC分类号： A61M15/00
CPC分类号： A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0045 , A61M15/0086 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/1055 , A61M16/1065 , A61M16/1075 , A61M2202/064

69. 发明公开

EP2817053A1 NASAL DELIVERY DEVICES 有权转让
标题翻译：器件用于鼻发布
公开(公告)号：EP2817053A1
公开(公告)日：2014-12-31
申请号：EP13711301.5
申请日：2013-02-25
申请人： Optinose AS
发明人： DJUPESLAND, Per Gisle , DUDGEON, Kate , GORDON, Joseph , GUARRAIA, Mark , LECLERC, Michael , MAHMOUD, Ramy A
IPC分类号： A61M15/08
CPC分类号： A61M15/08 , A61M15/0021 , A61M2202/04 , A61M2202/064 , A61M2205/586 , A61M2210/0618 , A61M2210/0625
摘要： A nasal delivery device comprising: a housing (15); a nosepiece (17) for fitting to a nasal cavity of a subject; a mouthpiece (19) through which the subject in use exhales; and a substance supply unit (21) including an actuation member (23) which extends from one end of the housing and is manually actuated to deliver substance to the nasal cavity of the subject; wherein the housing includes a grip section (27) which is disposed at the one end of the housing from which the actuation member extends, said grip section comprising a first, distal part (28) including at least one projecting grip element (29) by which the subject grips the housing in actuating the actuation member, and a second, proximal part (31) providing a recess (33) in which fingers of the subject are located, said recess promoting proper orientation of the delivery device in a hand of the subject.

70. 发明授权

EP2462972B1 Nasal delivery devices 有权转让
标题翻译：鼻腔给药装置
公开(公告)号：EP2462972B1
公开(公告)日：2014-04-16
申请号：EP12001499.8
申请日：2005-09-15
申请人： Optinose AS
发明人： Djupesland, Per, Gisle, Dr. , Hafner, Roderick, Peter, Dr. , Sheldrake, Colin, David, Dr.
IPC分类号： A61M15/00 , A61M15/08
CPC分类号： A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0045 , A61M15/0086 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/1055 , A61M16/1065 , A61M16/1075 , A61M2202/064

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