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51. 发明公开

EP0544839A1 MEDICAL DRUG FORMULATION AND DELIVERY SYSTEM 失效
标题翻译： Arzneimittel Zubereitungs- und Verabrechnungssystem。
公开(公告)号：EP0544839A1
公开(公告)日：1993-06-09
申请号：EP91920741.0
申请日：1991-08-20
申请人： ABBOTT LABORATORIES
发明人： KRUGER, Robert, J. , FREDERICK, Warren, P. , HELGREN, R., Hayes , LARKIN, Mark, E. , MAYORAL, Joaquin , SCHMOLESKY, Brad, A. , SICZEK, Roman, W. , TIMMONS, Kenneth, J. 1988 Green Bay Road
IPC分类号： A61M1 , B01D61 , B01D63 , C02F1
CPC分类号： B01D63/106 , A61M1/1643 , A61M1/1662 , A61M1/28 , A61M1/281 , A61M1/284 , A61M1/288 , A61M2205/3613 , B01D61/022 , B01D63/103 , B01D63/12 , B01D2311/08 , B01D2313/086 , B01D2313/143 , B01D2313/24 , C02F1/441 , B01D2311/14 , B01D2311/165
摘要： Formulation et système de diffusion d'un produit médical qui comprend un dispositif d'osmose inversée servant à purifier l'eau provenant d'une source et comportant un boîtier pourvu d'une entrée pour la circulation de l'eau provenant de la source, une première sortie pour la circulation de l'eau purifiée provenant du boîtier et une deuxième sortie pour la circulation de l'eau usée restant après purification. Un premier ensemble multicouches d'osmose inversée est situé à l'intérieur du boîtier, en communication fluidique avec l'entrée, dans le but de purifier au moins une première partie de l'eau provenant de la source. On peut placer des substances chimiques de traitement d'eau dans un noyau autour duquel s'enroule le premier ensemble multicouches d'osmose inversée. Les substances chimiques de traitement sont en communication fluidique avec le premier ensemble multicouches d'osmose inversée pour recevoir la première partie d'eau purifiée et en supprimer au moins les contaminants chimiques. Un deuxième ensemble multicouches d'osmose inversée s'enroule également sur le noyau et se trouve en communication fluidique avec les substances chimiques de traitement d'eau pour recevoir l'eau purifiée chimiquement pour en purifier au moins une deuxième partie. Le deuxième ensemble multicouches d'osmose inversée est en communication fluidique avec la première sortie pour permettre la circulation de la deuxième partie d'eau purifiée à travers ladite sortie. Selon un mode de réalisation préféré, le premier et le deuxième ensembles d'osmose inversée sont solidaires en position contiguë. Selon un autre mode de réalisation, ils s'enroulent autour du noyau en position intercalée. L'invention décrit également un procédé de construction d'un dispositif d'osmose inversée, un système de dialyse péritonéale et des systèmes de traitement alternatifs intégrant ledit dispositif ainsi que des procédés de traitement correspondants.
摘要翻译：药物制剂和递送系统包括用于净化来自源的水的反渗透装置，包括具有用于从源通过水的入口的壳体，用于从壳体通过净化水的第一出口和用于通过废物的第二出口净化后剩余水。第一反渗透多层组件设置在壳体内，与入口流体连通，用于从源净化至少第一部分水。水处理化学品可以位于卷绕第一储备渗透多层组件的芯中。处理化学品与第一反渗透多层组件流体连通以接收第一纯化部分的水并且至少从其中去除化学污染物。第二反渗透多层组件也缠绕在芯上并与水处理化学品流体连通以接收用于纯化其至少第二部分的化学净化水。第二储备渗透多层组件与第一出口流体连通，以允许第二部分净化水通过其中。还公开了形成反渗透装置的方法，腹膜透析治疗系统和包含这种装置的替代治疗系统以及相应的治疗方法。

52. 发明公开

EP0498382A1 Continuous peritoneal dialysis system 失效
标题翻译： Gerätund Verfahren zur kontinuierlichen Peritonaldialyse。
公开(公告)号：EP0498382A1
公开(公告)日：1992-08-12
申请号：EP92101866.9
申请日：1992-02-05
申请人： Peabody, Alan M.
发明人： Peabody, Alan M. , Boag, James T. , Walters, Ted M.
IPC分类号： A61M1/28
CPC分类号： A61M1/287 , A61M1/1643 , A61M1/1647 , A61M1/168 , A61M1/1682 , A61M1/1686 , A61M1/1688 , A61M1/28 , A61M1/281 , A61M1/284 , A61M2205/3393
摘要： A peritoneal dialysis system of the continuous flow type includes a reverse osmosis unit which prepares sterilized and filtered water. The process, which may be used with a single or double catheter, includes proportioning water, dialysis-concentrate, and dextrose to provide a dialysis fluid which is then heated and sterilized. The fluid may be accumulated in a reservoir. Load cells and/or flowmeters are utilized to measure the flow rate of the fluid in and out of the peritoneal cavity, either simultaneously or cyclic, and control the amount of fluid in the cavity. Preferably, the process and system includes a double flow catheter in which the flow of dialysis fluid through the inflow passage and the outflow passage are simultaneous. During this time, the volume of fluid in the peritoneal cavity is monitored by an ultrasonic or other suitable sensor so that over extension of the cavity does not occur. In a preferred tidal dialysis regime, a desired number of fill and partial drain cycles are performed wherein a puddle of dialysis fluid always remains in the cavity.
摘要翻译：连续流式的腹膜透析系统包括反渗透单元，其制备灭菌和过滤的水。可以与单导管或双导管一起使用的方法包括配水，透析浓缩物和右旋糖，以提供透析液，然后将其加热灭菌。流体可以积聚在储存器中。负载传感器和/或流量计用于测量流体进出腹腔的流速，同时或循环，并控制空腔中的流体量。优选地，该方法和系统包括双流导管，其中通过流入通道和流出通道的透析流体的流动是同时的。在此期间，通过超声波或其它合适的传感器监测腹膜腔中的流体体积，以致不会发生腔的过度延伸。在优选的潮汐透析方案中，执行所需数量的填充和部分排水循环，其中透析液的水坑总是保留在空腔中。

53. 发明公开

EP0354061A2 Apparatus for in vivo plasma separation 失效
标题翻译： Vorrichtung und Verfahren zur Abtrennung von Plasma in vivo。
公开(公告)号：EP0354061A2
公开(公告)日：1990-02-07
申请号：EP89307973.1
申请日：1989-08-04
申请人： HEALTHDYNE, INC.
发明人： Gorsuch, Reynolds George Francis , Atkin, John
IPC分类号： A61M1/34 , B01D63/02 , B01D61/14 , B01D61/28
CPC分类号： A61B5/14528 , A61B5/14557 , A61M1/1643 , A61M1/1678 , A61M1/1696 , A61M1/34 , A61M1/3403 , A61M1/3406 , A61M1/3479 , A61M1/3486 , A61M2202/046 , A61M2205/3331 , A61M2205/3553 , A61M2205/3584 , A61M2205/50 , A61M2202/0042
摘要： An apparatus for the continuous in vivo separation of plasma from other blood components comprising a bundle of microporous hollow fibers inserted into the vena cava. The fibers are sized to permit diffusion of plasma through the fiber pores but not cellular or other larger blood components. The fibers are in fluid communication with a dual lumen catheter which removes plasma from the hollow fibers to a treatment system and returns treated plasma to the bloodstream. The apparatus can be incorporated into an ambulatory plasmapheresis system for providing continuous plasma treatment while the user is mobile.
摘要翻译：用于从其它血液成分连续体内分离血浆的装置，包括插入到腔静脉中的一组微孔中空纤维。这些纤维的尺寸允许血浆扩散通过纤维孔，但不允许细胞或其它更大的血液成分扩散。纤维与双腔导管流体连通，其将等离子体从中空纤维移除到治疗系统，并将处理的血浆返回到血流。该装置可以并入到动态血浆置换系统中，用于在用户可移动时提供连续的等离子体治疗。

54. 发明授权

EP0112104B1 Apparatus for peritoneal dialysis 失效
标题翻译：眼部透析装置
公开(公告)号：EP0112104B1
公开(公告)日：1988-05-18
申请号：EP83307358.8
申请日：1983-12-02
申请人： Japan Medical Supply Co., Ltd.
发明人： Yamane, Seiji , Oda, Kazuyuki
IPC分类号： A61M1/28
CPC分类号： A61M1/28 , A61M1/1643 , A61M5/445 , A61M2205/3393

55. 发明授权

EP3903850B1 BLOOD PURIFICATION DEVICE 有权
公开(公告)号：EP3903850B1
公开(公告)日：2024-10-30
申请号：EP19905739.9
申请日：2019-08-29
IPC分类号： A61M1/16 , A61M1/36
CPC分类号： A61M1/1643 , A61M2205/339320130101 , A61M2205/6020130101 , A61M2205/1820130101 , A61M2205/50220130101 , A61M1/3644 , A61M1/367 , A61M1/3623

56. 发明授权

EP3842083B1 BLOOD PURIFICATION APPARATUS 有权
公开(公告)号：EP3842083B1
公开(公告)日：2024-06-05
申请号：EP19882467.4
申请日：2019-11-07
IPC分类号： A61M1/16 , A61M1/34
CPC分类号： A61M1/1643 , A61M2205/337920130101

57. 发明公开

EP3334476A1 PERITONEALDIALYSEGERÄT 有权
公开(公告)号：EP3334476A1
公开(公告)日：2018-06-20
申请号：EP16754190.3
申请日：2016-08-10
申请人： Fresenius Medical Care Deutschland GmbH
发明人： ZEYHER, Peter , FRITSCH, Kim
IPC分类号： A61M1/28 , G01G23/06 , G01G23/08 , G01G23/10 , G01G23/12 , A61M1/16 , G01G23/00
CPC分类号： A61M1/1643 , A61M1/28 , A61M2205/3379 , A61M2205/3393 , G01G19/56 , G01G23/3735
摘要： The invention relates to a peritoneal dialysis device having at least one device housing and at least one drain shell for receiving one or more solution bags for storing used dialysate, wherein the drain shell is connected to at least one weighing cell such that the weight of the drain shell can be detected by means of the weighing cell, wherein there is at least one damping system in order to prevent inadmissible force from being transmitted to the weighing cell, wherein the damping system has at least one damper to which the drain shell is directly or indirectly fastened, wherein the damper is connected to the weighing cell such that the weight of the drain shell having effect thereupon is transferred to the weighing cell.

58. 发明授权

EP2968720B1 EXTRACORPOREAL BLOOD TREATMENT APPARATUS WITH RESERVOIR STATUS LIGHTS 有权
标题翻译：及油藏状态指示灯体外血液处理设备
公开(公告)号：EP2968720B1
公开(公告)日：2017-04-19
申请号：EP14716180.6
申请日：2014-03-14
申请人： Gambro Lundia AB
发明人： O'MAHONY, John
IPC分类号： A61M1/14 , A61M1/34
CPC分类号： A61M1/1643 , A61M1/14 , A61M1/34 , A61M1/367 , A61M2205/3306 , A61M2205/3393 , A61M2205/50 , G01F23/20 , G01G17/04 , G01G19/14 , G01G23/32
摘要： Extracorporeal blood treatment apparatus with reservoir status lights and methods of monitoring reservoir status using the same are described. The extracorporeal blood treatment apparatus include a plurality of reservoir scales (30), each of which is configured to weigh a reservoir (32) used in connection with the extracorporeal blood treatment apparatus. A plurality of reservoir status lights (40) are provided, with one or more of the reservoir status lights (40) associated with one of the reservoir scales (30). The one or more reservoir status lights (40) associated with one of the reservoir scales (30) emit light from a location that is closer to their associated reservoir scale than to any other reservoir scale of the extracorporeal blood treatment apparatus.

59. 发明授权

EP3015123B1 Acute renal replacement therapy apparatus 有权
标题翻译：急性肾脏替代治疗设备
公开(公告)号：EP3015123B1
公开(公告)日：2017-03-22
申请号：EP14190925.9
申请日：2014-10-29
申请人： B. Braun Avitum AG
发明人： István, Golarits , Botond, Tényi
IPC分类号： A61M1/34 , A61M1/16
CPC分类号： A61M1/3451 , A61M1/16 , A61M1/1615 , A61M1/1643 , A61M1/1647 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M1/342 , A61M1/3441 , A61M1/3607 , A61M1/3663 , A61M2205/3331 , A61M2205/3334 , A61M2205/3379 , A61M2205/3393 , A61M2205/50
摘要： An acute renal replacement therapy apparatus comprises at least two feedback control means (110, 120), each including an estimated volume calculation means (112, 122) arranged to calculate an estimated volume based on a set flow, a comparing means (114, 124) arranged to compare the estimated volume with a measured volume, a volume deviation determining means (114, 124) arranged to determine a volume deviation based on the result of the comparison, a correction calculation means (116, 126) arranged to calculate a correction amount based on the determined volume deviation, a flow control generation means (116, 126) arranged to generate a controlled flow control signal based on the calculated correction amount and the set flow, and a feedback control output means (118, 128) arranged to output the controlled flow control signal to a pump individually associated with each feedback control means and forwarding fluid from a fluid source and/or pulling fluid into a fluid sink; and a flow correction distribution means (200) including an input means (210) arranged to input correction required signals calculated by and output from the correction calculation means in each of the at least two feedback control means, a limited correction signal calculation means (230) arranged to calculate a limited correction signal for each of the input correction required signals, and an output means arranged to output each calculated limited correction signal to the feedback control means from which its underlying correction required signal has been received.

60. 发明公开

EP3071251A1 VORRICHTUNG UND VERFAHREN ZUM BILANZIEREN VON FLÜSSIGKEITEN FÜR EINE EXTRAKORPORALE BLUTBEHANDLUNGSVORRICHTUNG 有权
标题翻译：装置和方法资产负债表纸液体在体外血液处理设备
公开(公告)号：EP3071251A1
公开(公告)日：2016-09-28
申请号：EP14799153.3
申请日：2014-11-14
申请人： Fresenius Medical Care Deutschland GmbH
发明人： PETERS, Arne , WIKTOR, Christoph
IPC分类号： A61M1/16
CPC分类号： A61M1/1635 , A61M1/1643 , A61M1/1647 , A61M2205/17
摘要： The invention relates to a device and method for balancing fluids for an extracorporeal blood treatment device comprising a blood treatment unit. The device according to the invention and method according to the invention are based on the monitoring of an inner fluid system I, which comprises the blood treatment unit (8), and an outer fluid system, which supplies the inner fluid system with fresh fluid and/or removes waste liquid from it. The balancing device according to the invention, has a monitoring device A, which comprises a processing unit (27), which is configured such that the volume, or a variable of the liquid (8) correlated with the volume, which is supplied to a balancing unit (8) is compared with the volume or with the volume-correlated variable of the liquid to be removed from the balancing unit. On the basis of the ratio of the volume or of the volume-correlated variable of the fluid supplied to or removed from the balancing unit (8), an incorrect balancing will be identified.
摘要翻译：本发明涉及一种用于平衡流体在体外血液处理装置，其包括血液处理单元的设备和方法。该装置雅丁发明和方法雅丁发明是基于内部流体系统I，其包括血液处理单元的监测（8）中，在外部流体系统，其与新鲜的液体，并将该内部流体系统从它/或移除废液。雅丁发明的平衡装置，具有监视设备A，其包含被配置成检查做的体积，或液体的变量（8）与该卷相关联的处理单元（27），所有的，所有这一切都被提供给一个平衡单元（8）与体积或与液体的体积相关变量以从平衡单元被移除相比。上的卷的或者提供给或从所述平衡单元（8），以不正确的平衡移除的流体的体积相关变量的比率的基础上，将被识别。

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