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    • 52. 发明公开
    • METHODS OF SOIL PEST CONTROL
    • VERFAHREN ZURBODENSCHÄDLINGSBEKÄMPFUNG
    • EP2887802A2
    • 2015-07-01
    • EP13753141.4
    • 2013-08-16
    • Syngenta Participations AG
    • EL QACEMI, MyriemCASSAYRE, Jérôme YvesKURTZ, Benedikt
    • A01N43/36A01N43/653A01N43/80A01P7/04
    • A01N47/18A01N43/36A01N43/653A01N43/80A01N47/38
    • The present invention provides a method of controlling and/or preventing soil-dwelling pests in useful plants comprising applying to the locus of the useful plant or treating propagation material thereof, preferably a seed, with a compound of formula (I), wherein -B
      1 -Β
      2 -Β
      3 - is -C=N-O-, -C=N-CH2-, or -N-CH
      2 -CH
      2 -; R
      1 is trifluoromethyl, difluoromethyl or chlorodifluoromethyl; R
      2 is group X X
      2 is C-X
      6 or nitrogen; X
      1 , X
      3 and X
      6 are independently hydrogen, halogen or trihalomethyl, wherein at least one of X
      1 , X
      3 and X
      6 is not hydrogen; A is selected from A1 to A5 Y
      1 is C-R
      6 , CH or nitrogen; Y
      2 and Y
      3 are independently CH or nitrogen; wherein no more than two of Y
      1 , Y
      2 and Y
      3 are nitrogen and wherein Y
      2 and Y
      3 are not both nitrogen; R
      5 is hydrogen, halogen, cyano, nitro, NH
      2 , C
      1 -C
      4 alkyl, C
      1 -C
      4 aloalkyl, C
      3 -C
      5 cycloalkyl, C
      3 - C
      5 halocycloalkyl, C
      1 -C
      2 alkoxy, or C
      1 -C
      2 haloalkoxy; providing that when A is A3 or A4 R
      5 is not hydrogen; R
      6 when present together with R
      5 forms a -CH=CH-CH=CH- bridge; R
      7 is C
      1 -C
      4 alkyl; R
      8 is C
      1 -C
      4 alkyl, C
      1 -C
      4 haloalkyl, C
      1 -C
      4 alkoxy(C
      1 -C
      4 )alkyl, C
      1 -C
      4 alkylthio(C
      1 -C
      4 )alkyl, C
      1 -C
      4 alkylsulfmyl(C
      1 -C
      4 )alkyl, C
      1 -C
      4 alkylsulfonyl(C
      1 -C
      4 )alkyl, C
      3 -C
      6 cycloalkyl, C
      3 -C
      6 cycloalkyl(C
      1 -C
      4 )alkyl-, or tetrahydrofuranyl; R
      9 is C
      1 -C
      4 alkyl, C
      1 -C
      4 haloalkyl, C
      1 -C
      4 alkyl-O-CH
      2 -, C
      1 -C
      4 haloalkyl-O-CH
      2 -,C
      3 -C
      6 cycloalkyl, C
      3 -C
      6 cycloalkyl-CH
      2 -, C
      1 -C
      4 alkyl-S-CH
      2 -, C
      1 -C
      4 alkyl-S(O)-CH
      2 -, or C
      1 -C
      4 alkyl-S(O
      2 )-CH
      2 ; each Z is independently halogen, C
      1 -C
      12 alkyl or C
      1 -C
      12 alkyl substituted by one to five R
      12 , nitro, C
      1 -C
      12 alkoxy or C
      1 -C
      12 alkoxy substituted by one to five R
      12 cyano, C
      1 -C
      12 alkylsulfinyl, C
      1 -C
      12 alkylsulfonyl, C
      1 -C
      12 haloalkylsulfinyl, C
      1 -C
      12 haloalkylsulfonyl, hydroxyl or thiol; each R
      12 is halogen, cyano, nitro, hydroxy, C
      1 -C
      8 alkoxy-, C
      1 -C
      8 haloalkoxy-, mercapto, C
      1 -C
      8 alkylthio-, or CpCghaloalkylthio; and k is 0, 1,2 or 3; wherein when the pest is corn rootworm, R
      8 is cyclopropyl when A is A2 and -B
      1 -B
      2 -B
      3 - is -N-CH
      2 -CH
      2 -; Preferably the soil-dwelling pest is selected from corn rootworm, wireworms, grubs, in particular white grubs (e.g. Phyllophaga sp., Diloboderus sp., Popillia japonica), termites (in particular for sugar cane), subterraneous stinkbugs (e.g. Scaptocoris sp.), cutworms (e.g. agrotis sp.), millipedes (e.g. Julus sp.) and broca gigante (e.g. Telchin licus).
    • 本发明提供了一种控制和/或预防有用植物中的土壤污染的害虫的方法,其包括向所述有用植物的场所施用或用式(I)化合物处理其优选种子的繁殖材料,其中-B1 -B2-B3-是-C≡N-O-,-C≡N-CH2-或-N-CH2-CH2-; R1是三氟甲基,二氟甲基或氯二氟甲基; R2是基团X X2是C-X6或氮; X1,X3和X6独立地为氢,卤素或三卤代甲基,其中X1,X3和X6中的至少一个不是氢; A选自A1至A5,Y1为C-R6,CH或氮; Y2和Y3独立地是CH或氮; 其中Y1,Y2和Y3中不超过两个是氮,并且其中Y2和Y3不都是氮; R5是氢,卤素,氰基,硝基,NH2,C1-C4烷基,C1-C4卤代烷基,C3-C5环烷基,C3-C5卤代环烷基,C1-C2烷氧基或C1-C2卤代烷氧基; 当A为A3或A4时,R5不为氢; 当与R 5一起存在时,R6形成-CH = CH-CH = CH-桥; R7是C1-C4烷基; R8是C1-C4烷基,C1-C4卤代烷基,C1-C4烷氧基(C1-C4)烷基,C1-C4烷硫基(C1-C4)烷基,C1-C4烷基亚磺酰基(C1-C4)烷基,C1-C4烷基磺酰基(C1-C4)烷基, C 3 -C 6环烷基,C 3 -C 6环烷基(C 1 -C 4)烷基或四氢呋喃基; R9是C1-C4烷基,C1-C4卤代烷基,C1-C4烷基-O-CH2-,C1-C4卤代烷基-O-CH2-,C3-C6环烷基,C3-C6环烷基-CH2-,C1-C4烷基-S-CH2-,C1- C 1-4烷基-S(O)-CH 2 - 或C 1 -C 4烷基-S(O 2)-CH 2; 每个Z独立地是卤素,被一至五个被一至五个R 12氰基,C 1 -C 12烷基亚磺酰基,C 1 -C 12烷基磺酰基,C 1 -C 12卤代烷基亚磺酰基,C 1 -C 12烷基亚磺酰基,C 1 -C 12烷基亚磺酰基,C 1 -C 12烷基亚磺酰基, -C 12卤代烷基磺酰基,羟基或硫醇; 每个R 12是卤素,氰基,硝基,羟基,C 1 -C 8烷氧基 - ,C 1 -C 8卤代烷氧基 - ,巯基,C 1 -C 8烷硫基 - 或C 1 - 卤代烷硫基; 且k为0,1,2或3; 其中当害虫为玉米根虫时,当A为A2且-B1-B2-B3-为-N-CH2-CH2-时,R8为环丙基; 优选的是,土壤有害生物选自玉米根虫,丝虫,gr s,尤其是白ub(例如P aga aga aga,us us,,,ica ica ica ica。。。。。。。。。。。。。。。。。。。。。。。,,,,,。。。。。。 ),夜蛾(例如农杆菌属),千足虫(例如茱萸属)和broca gigante(例如Telchin licus)。
    • 54. 发明公开
    • INSECTICIDAL COMPOUNDS
    • 杀虫化合物
    • EP2714666A1
    • 2014-04-09
    • EP12724985.2
    • 2012-05-30
    • Syngenta Participations AG
    • CASSAYRE, Jérôme, YvesRENOLD, PeterEL QACEMI, MyriemPITTERNA, ThomasTOUEG, Julie, Clementine
    • C07D261/02C07D327/02A01N43/80
    • A01N43/80C07D261/02C07D327/02C07D411/12C07D413/12C07D413/14
    • The present invention provides compounds of formula (I): wherein A1, A2, A3 and A4 are independently of one another C—H, C—R5, or nitrogen; B1—B2—B3—B4 is —CH2—C═N—CH2—, —CH2—N—CH2—CH2—, —CH2—C═CH-0- or —CH═C—CH2-0-; G1 is oxygen or sulfur; L is a single bond or C1-C8alkylene; R1 is hydrogen, C1-C8alkyl, C1-C8alkylcarbonyl-, C1-C8alkoxy, C2-C8alkenyl, C2-C8alkynyl, C1-C8alkoxy-C1-C8alkyl, aryl or aryl substituted by one to three R6, or R1 is heterocyclyl or heterocyclyl substituted by one to three R6 or C1-C8alkoxycarbonyl-; R2 is hydrogen, C1-C8haloalkyl or C1-C8alkyl; R3 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to three R6, or R4 is heterocyclyl or heterocyclyl substituted by one to three R6; Y1 is CR7R8, C═O or C═S; Y2, Y3 and Y4 are independently CR7R8, C=0, C═S, N—R9, O, S, SO or SO2; wherein at least two adjacent ring atoms in the ring formed by Y1, Y2, Y3 and Y4 are heteroatoms; each R7 and R8 is independently hydrogen, halogen, C1-C8alkyl, or C1-C8haloalkyl; and R5, R6, R7, R8 and R9 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.
    • 本发明提供了式(I)的化合物:其中A 1,A 2,A 3和A 4彼此独立地为C-H,C-R 5或氮; B 1 -B 2 -B 3 -B 4是-CH 2 -C = N-CH 2 - , - CH 2 -N-CH 2 -CH 2 - , - CH 2 -C = CH-O- 或-CH = C-CH 2 -O-; G 1是氧或硫; L是单键或C 1 -C 8亚烷基; R 1是氢,C 1 -C 8烷基,C 1 -C 8烷基羰基 - ,C 1 -C 8烷氧基,C 2 -C 8链烯基,C 2 -C 8炔基,C 1 -C 8烷氧基-C 1 -C 8烷基,芳基或 被一至三个R 6取代的芳基,或者R 1为被一至三个R 6或C 1 -C 8烷氧羰基取代的杂环基或杂环基; R 2是氢,C 1 -C 8卤代烷基或C 1 -C 8烷基; R 3是C 1 -C 8卤代烷基; R 4为被一至三个R 6取代的芳基或芳基,或者R 4为被一至三个R 6取代的杂环基或杂环基; Y 1是CR 7 R 8,C = O或C = S; Y 2,Y 3和Y 4独立地为CR 7 R 8,C = O,C = S,N-R 9,O,S,SO或SO 2; 其中由Y 1,Y 2,Y 3和Y 4形成的环中至少两个相邻的环原子是杂原子; 每个R 7和R 8独立地为氢,卤素,C 1 -C 8烷基或C 1 -C 8卤代烷基; 并且R 5,R 6,R 7,R 8和R 9如权利要求中所定义。 本发明还涉及制备这些化合物的方法和中间体,包含这些化合物的杀虫,杀螨,杀线虫和杀软体动物组合物,以及使用这些化合物防治昆虫,螨,线虫和软体动物害虫的方法。