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51. 发明公开

EP1295611A1 OLIGONUCLEOTIDE-TRANSFERRING PREPARATIONS 有权
标题翻译： VERBINDUNGENFÜRDEN TRANSVER VON OLIGONUKLEOTIDEN
公开(公告)号：EP1295611A1
公开(公告)日：2003-03-26
申请号：EP01938732.3
申请日：2001-06-19
申请人： Sumitomo Pharmaceuticals Company, Limited , KOKEN CO., LTD.
发明人： KUBOTA, Shunichiro , TERADA, Masaaki , OCHIYA, Takahiro, 218, National Cancer Center , ITOH, Hiroshi , FURUSE, Masayasu , SANO, Akihiko , NAGAHARA, Shunji, 3-348, Sumitomokagaku,
IPC分类号： A61K48/00 , A61K31/711 , A61K31/7105 , A61K47/42
CPC分类号： A61K9/0024 , A61K9/0019 , A61K9/127 , A61K9/19 , A61K9/2063 , A61K9/7007 , A61K31/7105 , A61K31/711 , A61K47/42 , A61K48/00 , A61K48/0008
摘要： Preparations for transferring efficiently oligonucleotides necessary in antisense therapy or the like into animal cells so as to be useful in treatment for various diseases, which comprises a collagen as an essential component are provided.
摘要翻译：提供将反义治疗等中必需的寡核苷酸有效转移到动物细胞中的制剂，以便用于治疗包括胶原蛋白作为必要成分的各种疾病。

52. 发明授权

EP0693277B1 Use of a solution or liquid dispersion for the manufacture of a medicament for occluding a lacrimal canaliculi 失效
标题翻译：使用用于制造药物的用于切断泪管的输注溶液或分散体
公开(公告)号：EP0693277B1
公开(公告)日：2001-05-16
申请号：EP95109708.8
申请日：1995-06-22
申请人： KOKEN CO. LTD.
发明人： Hamano, Takashi , Miyata, Teruo, c/o Koken Bioscience Institute , Ogawara, Takeshi
IPC分类号： A61F9/00
CPC分类号： A61L31/145 , A61F9/00772 , A61L31/041 , A61L31/043 , A61L31/044 , A61L2430/16 , A61L31/046 , A61L31/045 , A61F9/00 , C08L89/06 , C08L5/08 , C08L5/00

53. 发明公开

EP0987634A1 BOUNDARY SCANNING ELEMENT AND COMMUNICATION EQUIPMENT USING THE SAME 失效
标题翻译：边界扫描元件和使用该元件的通信设备
公开(公告)号：EP0987634A1
公开(公告)日：2000-03-22
申请号：EP98923083.4
申请日：1998-06-02
申请人： KOKEN CO., LTD.
发明人： NAGOYA, Mitsugu
IPC分类号： G06F11/22 , G01R31/28
CPC分类号： G01R31/318536 , G01R31/2815 , G01R31/318533 , G01R31/318572
摘要： Provided is a boundary scan element which includes a plurality of input terminal side boundary cells which are connected in series, each being individually allocated to corresponding one of input terminals; a plurality of output terminal side boundary cells which are connected in series, each being individually allocated to corresponding one of output terminals; a TAP circuit for controlling input/output of data to/from the boundary cells on the input/output terminal sides; a TDI terminal for receiving serial data to be supplied to the boundary cells; a TDO terminal for outputting the data from the boundary cells as serial data; a TCK terminal for receiving clock signals; and a TMS terminal for receiving a mode signal to switch an operation mode of the TAP circuit, wherein the boundary cells on the input/output terminal sides are connected in parallel between the TDI and TDO terminals, respectively, and wherein two sets of combinations composed of the input terminal side boundary cells, the output terminal boundary cells, the TDI terminal, the TDO terminal and the TAP circuit are provided.
摘要翻译：提供了一种边界扫描元件，其包括串联连接的多个输入端子侧边界单元，每个输入端子侧边界单元被分别分配给相应的一个输入端子; 多个输出端子侧边界单元，其串联连接，每个输出端子侧边界单元被分别分配给对应的一个输出端子; TAP电路，用于控制输入/输出端侧上的边界单元的数据的输入/输出; 用于接收要提供给边界单元的串行数据的TDI终端; TDO终端，用于将来自边界单元的数据作为串行数据输出; 用于接收时钟信号的TCK端子; 以及用于接收模式信号以切换TAP电路的操作模式的TMS终端，其中输入/输出终端侧上的边界单元分别并联连接在TDI和TDO终端之间，并且其中两组组合输入端子侧边界单元，输出端子边界单元，TDI端子，TDO端子和TAP电路被提供。

54. 发明公开

EP0987633A1 COMMUNICATION SYSTEM 失效
标题翻译：通讯系统
公开(公告)号：EP0987633A1
公开(公告)日：2000-03-22
申请号：EP98923061.0
申请日：1998-06-01
申请人： KOKEN CO., LTD.
发明人： NAGOYA, Mitsugu
IPC分类号： G06F11/22 , G01R31/28
CPC分类号： G01R31/318536 , G01R31/2815 , G01R31/318533 , G01R31/318572
摘要： There is provided a communication system including: boundary scan elements having a plurality of boundary cells individually assigned to respective input terminals and output terminals, a TAP circuit for controlling input and output of data to or from the boundary cells, a TDI terminal and TDO terminal for inputting or outputting serial data to or from the boundary cells, a TCK terminal to which a clock signal is input, and a TMS terminal to which a mode signal for switching the operation mode is input; a plurality of terminal units connected with the respective boundary scan elements; a communication controller connected in series with the boundary scan elements for individual control of the terminal units; incoming communication lines establishing individual connection between the boundary scan elements adjoining each other, and between the boundary scan elements and the communication controller; a outgoing communication line establishing connection between the communication controller and the boundary scan element positioned at the backmost; a clock signal line; a mode signal line; and a cable formed by binding up these communication lines and signal lines.
摘要翻译：提供了一种通信系统，包括：边界扫描元件，其具有分别分配给各个输入端子和输出端子的多个边界单元; TAP电路，用于控制到或来自边界单元的数据的输入和输出; TDI端子和TDO端子用于向边界单元输入或输出串行数据，输入时钟信号的TCK端子以及输入用于切换操作模式的模式信号的TMS端子; 多个终端单元，与相应的边界扫描元件连接; 与边界扫描元件串联连接的通信控制器，用于单独控制终端单元; 传入通信线路，建立彼此相邻的边界扫描元件之间以及边界扫描元件和通信控制器之间的个体连接; 建立通信控制器与位于最后面的边界扫描元件之间的连接的输出通信线; 时钟信号线; 模式信号线; 以及通过捆绑这些通信线路和信号线而形成的电缆。

55. 发明公开

EP0987632A1 BOUNDARY SCAN ELEMENT AND COMMUNICATION DEVICE MADE BY USING THE SAME 失效
标题翻译： KOMMUNIKATIONSVORRICHTUNG DIESES VERWENDET的SCHNITTSTELLENABTASTUNGSELEMENT
公开(公告)号：EP0987632A1
公开(公告)日：2000-03-22
申请号：EP98921883.9
申请日：1998-05-29
申请人： KOKEN CO., LTD.
发明人： NAGOYA, Mitsugu
IPC分类号： G06F11/22 , G01R31/28
CPC分类号： G01R31/318536 , G01R31/2815 , G01R31/318533 , G01R31/318572
摘要： There are provided a boundary scan element including a plurality of input-terminal-side boundary cells connected in series and assigned individually to respective input terminals, a plurality of output-terminal-side boundary cells connected in series and assigned individually to respective output terminals, a TAP circuit for controlling input and output of data to or from the input-terminal-side and output-terminal-side boundary cells, a TDI terminal for inputting serial data to be provided to the boundary cells, a TDO terminal for outputting data from the boundary cells as serial data, a TCK terminal to which a clock signal is input, and a TMS terminal to which a mode signal is input to switch an operation mode of the TAP circuit, characterized in that the input-terminal-side boundary cells and the output-terminal-side boundary cells are connected in parallel between the TDI terminal and the TDO terminal; and a communication system using the same.
摘要翻译：提供了一种边界扫描元件，其包括串联连接并分别分配给各个输入端子的多个输入端侧边界单元，串联连接并分别分配给各个输出端子的多个输出端侧边界单元， TAP电路，用于控制输入和输出来自输入端侧和输出端边界单元的数据的输入和输出; TDI端子，用于输入要提供给边界单元的串行数据; TDO端子，用于从作为串行数据的边界单元，输入时钟信号的TCK端子和输入模式信号的TMS端子来切换TAP电路的工作模式，其特征在于，输入端侧边界单元输出端侧边界单元并联在TDI端子和TDO端子之间; 以及使用该通信系统的通信系统。

56. 发明授权

EP0460232B1 TUMOR CELL GROWTH INHIBITOR 失效
标题翻译：肿瘤细胞生长抑制因子
公开(公告)号：EP0460232B1
公开(公告)日：1998-03-18
申请号：EP91900944.9
申请日：1990-12-21
申请人： KOKEN CO., LTD.
发明人： IIJIMA, Kunihito , KATO, Haruki , NAGASU, Yoichiro
IPC分类号： A61K38/00 , A61K31/215 , A61K31/765
CPC分类号： A61K9/0019 , A61K38/04 , A61K47/26 , A61K47/34 , A61K31/765 , A61K2300/00
摘要： A tumor cell growth inhibitor which comprises 10 parts by weight of a low condensate and polymer of an α-hydroxy acid, 1 to 4 parts by weight of an oligopeptide containing at least one pyroglutamic acid residue, and 1 to 3 parts by weight of a stabilizer. Said α-hydroxy acid condensate and polymer mainly comprise a condensate of 2 to 10 molecules of an α-hydroxy acid, a polymer thereof, and metal salts thereof; said oligopeptide comprises an oligopeptide composed of 2 to 8 amino acid residues and containing at least one pyroglutamic acid residue and metal salts thereof; and said stabilizer comprises a sugar and a sugar alcohol.

57. 发明授权

EP0306256B1 Bioprosthetic valve 失效
标题翻译：人工生物瓣膜。
公开(公告)号：EP0306256B1
公开(公告)日：1994-03-09
申请号：EP88308000.4
申请日：1988-08-30
申请人： KOKEN CO. LTD.
发明人： Imamura, Eisaburo , Noishiki, Yasuharu , Koyanagi, Hitoshi , Miyata, Teruo , Furuse, Masayasu
IPC分类号： A61L27/00 , A61F2/04
CPC分类号： A61L27/3687 , A61F2/24 , A61F2/2412 , A61K35/34 , A61L2/0088 , A61L27/36 , A61L27/3625 , A61L27/507 , A61L2400/02 , Y10S623/915
摘要： A bioprosthetic valve comprising a biological tissue containing collagen which has been crosslinked with a polyepoxy compound.

58. 发明授权

EP0230647B1 Method for producing a sustained release formulation 失效
标题翻译：生产持续释放配方的方法
公开(公告)号：EP0230647B1
公开(公告)日：1993-03-31
申请号：EP86117946.3
申请日：1986-12-23
申请人： SUMITOMO PHARMACEUTICALS COMPANY, LIMITED , KOKEN CO. LTD.
发明人： Fujioka, Keiji , Sato, Shigeji , Sasaki, Yoshio , Miyata, Teruo , Furuse, Masayasu , Naito, Hiromi
IPC分类号： A61K9/22
CPC分类号： A61K9/2063 , A61K9/1658 , A61K9/2018 , Y10S514/801

59. 发明授权

EP0101285B1 A method for culturing and isolating cells 失效
标题翻译：一种培养和分离细胞的方法
公开(公告)号：EP0101285B1
公开(公告)日：1991-07-31
申请号：EP83304573.5
申请日：1983-08-08
申请人： KOKEN CO. LTD.
发明人： Kasai, Shunji , Akaike, Toshihiro , Miyata, Teruo
IPC分类号： C12N5/00
CPC分类号： C12N5/0068 , C12N2533/54 , Y10S435/948

60. 发明公开

EP0326151A3 Improved controlled release formulation 失效
标题翻译：改进的控制释放公式
公开(公告)号：EP0326151A3
公开(公告)日：1991-03-13
申请号：EP89101428.4
申请日：1989-01-27
申请人： SUMITOMO PHARMACEUTICALS COMPANY, LIMITED , KOKEN CO. LTD.
发明人： Fujioka, Keiji Sumitomo Pharmaceuticals Co., Ltd. , Sato, Shigeji Sumitomo Pharmaceuticals Co., Ltd. , Tamura, Nobuhiko Sumitomo Pharmaceuticals Co., Ltd , Takada, Yoshihiro Sumitomo Pharmaceuticals Co.,Ltd , Sasaki, Yoshio c/o Sumitomo Pharmaceuticals Co.Ltd , Maeda, Miho c/o Sumitomo Pharmaceuticals Co.Ltd
IPC分类号： A61K47/00 , A61K9/22 , A61K9/20 , A61K9/00
CPC分类号： A61K9/2063 , A61K9/2013 , A61K47/12 , A61K47/183 , A61K47/42 , Y10S514/801 , Y10S514/964
摘要： A controlled release formulation which comprises an organic acidic compound or an acid anhydride or ester capable of generating one of the organic acidic compounds through hydrolysis together with an active ingredient and collagen as a carrier, said formulation being capable of exhibiting a predetermined release profile of the active ingredient. A process for producing said formulation is also provided.

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