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51. 发明公开

EP1860584A2 Systems and methods for providing individualized disease management 审中-公开
标题翻译： Systeme und Verfahren zur personalisierten Krankheitsbehandlung
公开(公告)号：EP1860584A2
公开(公告)日：2007-11-28
申请号：EP07252111.5
申请日：2007-05-23
申请人： Lifescan, Inc.
发明人： Harmon, Kirk C.
IPC分类号： G06F19/00
CPC分类号： G16H50/20 , G06F19/00 , G16H50/70
摘要： Systems and methods of individualized disease management are provided and use patient-specific, physician-defined rules to assist a patient in the management of their disease. The set of physician-defined rules for a patient can be maintained within the patient's blood glucose metering system and activated when a lifestyle event or blood glucose result is expected or recorded. Pattern analysis can be performed in real-time to provide physician-generated suggestions to a patient to positively influence their behavior toward managing their disease.
摘要翻译：提供个性化疾病管理的系统和方法，并使用患者特定的医师定义的规则来协助患者治疗其疾病。可以在患者的血糖计量系统内维持患者的医师定义的规则的集合，并且当预期或记录生活方式事件或血糖结果时被激活。模式分析可以实时进行，以向患者提供医生产生的建议，以积极地影响他们管理疾病的行为。

52. 发明公开

EP1840219A1 Systems and methods of discriminating control solution from a physiological sample 有权转让
标题翻译：系统和方法，用于从血液生理样品区分对照溶液
公开(公告)号：EP1840219A1
公开(公告)日：2007-10-03
申请号：EP07251388.0
申请日：2007-03-30
申请人： LifeScan, Inc.
发明人： Chatelier, Ronald C. , Hodges, Alastair McIndoe , Teodorczyk, Maria , Dato, Remedios
IPC分类号： C12Q1/00 , G01N27/49 , G01N33/487
CPC分类号： G01N27/3271 , C12Q1/001 , C12Q1/006 , G01N27/3274
摘要： Described herein are systems and methods for distinguishing between a control solution and a blood sample. In one aspect, the methods include using a test strip in which multiple current transients are measured by a meter electrically connected to an electrochemical test strip. The current transients are used to determine if a sample is a blood sample or a control solution based on at least two characteristics. Further described herein are methods for calculating a discrimination criteria based upon at least two characteristics. Still further described herein are system for distinguishing between blood samples and control solutions.
摘要翻译：描述为针对控制溶液和血液样品之间进行区分的系统和方法。在一个方面，所述方法包括使用在多个测试条，其电流瞬变通过在电化学测试条电连接到计进行测定。的电流瞬变被用于确定性地雷，如果样品是血液样品或对照溶液基于至少两个特征。进一步描述的是在用于计算基于至少两个特征的判别标准的方法。仍然在顷系统进一步描述用于血液样本和控制解决方案之间进行区分。

53. 发明公开

EP1839571A1 Methods for analyzing a sample in the presence of interferents 有权转让
标题翻译： Verfahren zur Probenanalyse在Anwesenheit von interferierenden Substanzen
公开(公告)号：EP1839571A1
公开(公告)日：2007-10-03
申请号：EP07251411.0
申请日：2007-03-30
申请人： LifeScan, Inc.
发明人： Chatelier, Ronald C. , Hodges, Alastair McIndoe , Verity, Bruce
IPC分类号： A61B5/00 , C12Q1/00 , G01N33/487
CPC分类号： A61B5/1486 , C12Q1/006 , G01N27/3274
摘要： Disclosed herein are methods and apparatus for determining analyte concentration in a rapid and accurate manner. The methods include depositing a physiological sample in an electrochemical cell and finding a first and second current transient. Peak current values are obtained from the first and second peak current values and used to reduce the influence of interferents in a current value. Based on this "corrected" current value, an accurate analyte concentration can be determined.
摘要翻译：本文公开了以快速和准确的方式测定分析物浓度的方法和装置。所述方法包括在电化学电池中沉积生理样品并找到第一和第二电流瞬变。从第一和第二峰值电流值获得峰值电流值，并用于减小干扰物在电流值中的影响。基于该“校正”电流值，可以确定准确的分析物浓度。

54. 发明公开

EP1780267A3 Amniotic fluid derived cells 有权
公开(公告)号：EP1780267A3
公开(公告)日：2007-08-01
申请号：EP06252751.0
申请日：2006-05-26
申请人： LifeScan, Inc.
发明人： Rezania, Alireza , Xu, Jean
IPC分类号： C12N5/08
CPC分类号： C12N5/0605 , C12N2500/02 , C12N2533/52 , C12N2533/54
摘要： This invention relates to an expandable population of amniotic fluid-derived cells that can be differentiated into a β-cell lineage. This invention also provides methods for isolating and expanding such amniotic fluid-derived cells, as well as related methods and compositions for utilizing such cells in the therapeutic treatment of diabetes.

55. 发明公开

EP1810616A1 Lancing device with dampener 有权
标题翻译： Lanzettenvorrichtung mitDämpfer
公开(公告)号：EP1810616A1
公开(公告)日：2007-07-25
申请号：EP07250221.4
申请日：2007-01-19
申请人： LifeScan, Inc.
发明人： Uschold, Robert
IPC分类号： A61B5/151
CPC分类号： A61B5/15194 , A61B5/150022 , A61B5/150152 , A61B5/150183 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/1519
摘要： A lancing device includes a housing, a moveable lancet holder configured to hold a lancet, a launching mechanism, a depth stop with a depth stop surface, and a dampener for dampening at least one of sound and vibration during lancing. The moveable lancet holder includes a lancet holder depth stop interface surface. In addition, the moveable lancet holder and launching mechanism are operatively connected to lance a target site with the lancet and the dampener is disposed between the lancet holder depth stop interface surface and the depth stop surface. Forward movement of the moveable lancet holder during lancing of a target site is stopped by engagement between the lancet holder depth stop interface surface, the dampener and the depth stop interface surface.
摘要翻译：一种采血装置包括壳体，构造成保持柳叶刀的可动柳叶刀夹持器，发射机构，具有深度止动表面的深度止动件和用于在穿刺期间抑制声音和振动中的至少一个的阻尼器。可动式的柳叶刀座包括柳叶刀座深度停止界面。另外，可动柳叶刀座和发射机构可操作地连接到刺血针的目标位置，而柳叶刀保持器深度限制界面和深度止动面之间设置有阻尼器。通过柳叶刀套深度限位接口表面，阻尼器和深度限制接口表面之间的接合来阻止可移动的刺血针保持件在目标位置的穿刺期间的向前运动。

56. 发明公开

EP1797909A2 Compositons and methods to create a vascularized environment for cellular transplantation 审中-公开
标题翻译：组合物和方法用于制备血管环境对细胞移植
公开(公告)号：EP1797909A2
公开(公告)日：2007-06-20
申请号：EP06256045.3
申请日：2006-11-27
申请人： LifeScan, Inc.
发明人： Xu, Jean , Harris, Ian R.
IPC分类号： A61L27/38 , A61L27/54
CPC分类号： A61L27/38 , A61L27/54 , A61L2300/252 , A61L2300/402 , A61L2300/41 , A61L2300/414 , A61L2300/604 , A61L2300/64
摘要： The present invention generally relates to biocompatible devices suitable for promoting the movement of cells from a first location to a second location and their retention in the second location. In particular, the present invention relates to an implant, comprising a biocompatible support loaded with at least one pharmaceutical agent capable promoting the movement of cells from a first location to a second location and their retention in the second location. The at least one pharmaceutical agent promotes vascularization at or near the implant site. Vascularization of the implanted support results in enhanced survival of cells optionally incorporated within the support. Methods for treating a disease or injury via implanting the support of the present invention are also provided.
摘要翻译：本发明基因的反弹涉及适用于电视节目预告婷生物相容性装置细胞从第一位置移动到第二位置及其在所述第二位置保持。特别地，本发明涉及一种在植入物，包括负载有至少一种药物活性剂能够宣传片婷细胞的运动从第一位置到第二位置及其在所述第二位置保持生物相容性支持。至少一个药剂在植入部位或其附近的血管促进。在细胞的存活增强植入支撑结果的血管形成在载体内可选地并入。因此，提供用于通过植入本发明的支撑治疗疾病或损伤的方法。

57. 发明公开

EP1752086A2 Kinematic fluorescence measurement band 审中-公开
标题翻译： Kinematischer Fluoreszenz-Messband
公开(公告)号：EP1752086A2
公开(公告)日：2007-02-14
申请号：EP06254166.9
申请日：2006-08-08
申请人： LifeScan, Inc.
发明人： Hayter, Paul G
IPC分类号： A61B5/00
CPC分类号： A61B5/1459 , A61B5/0059 , A61B5/14532 , A61B5/1455
摘要： A kinematic fluorescence measurement band for use with a fluorescent light-emitting bead implanted within a user's body includes a band configured for secure and removable positioned about a portion of the user's body, a base plate configured for attachment to the band and an optical plate. The optical plate includes a rigid member with a light emitter and a light detector attached thereto. The light emitter of the optical plate is configured for emitting light that is absorbed by the fluorescent light-emitting bead while the light detector is configured for detecting fluorescent light emitted by the fluorescent light-emitting bead. In addition, the base plate and optical plate are configured for kinematic attachment, detachment and kinematic reattachment to one another via a cone-shaped indent, a slot-shaped indent, and a flat surface independently disposed on either of the base or optical plates in opposing relationship to first, second and third spherical components disposed on the other of the base or optical plates.
摘要翻译：用于植入用户体内的荧光发光珠的运动学荧光测量带包括被配置用于围绕用户身体的一部分固定和移除的带，配置成附接到带的基板和光学板。光学板包括具有光发射器的刚性构件和附接到其上的光检测器。光学板的光发射器被配置为发射由荧光发光珠吸收的光，同时光检测器被配置为检测由荧光发光珠发射的荧光。此外，基板和光学板被构造成通过锥形凹口，槽形凹槽和独立地设置在基板或光学板中的任一个上的平坦表面相互运动学附接，分离和运动学重新附接与设置在基板或光学板的另一个上的第一，第二和第三球形部件相对的关系。

58. 发明授权

EP1360934B1 Devices and methods for accessing and analyzing physiological fluid 有权
标题翻译：装置和方法，用于提供和分析生理性液体
公开(公告)号：EP1360934B1
公开(公告)日：2006-12-06
申请号：EP03252883.8
申请日：2003-05-08
申请人： LifeScan, Inc.
发明人： Sohrab, Borzu
IPC分类号： A61B5/15
CPC分类号： A61B5/15159 , A61B5/150022 , A61B5/150213 , A61B5/150305 , A61B5/150358 , A61B5/150419 , A61B5/150442 , A61B5/150809 , A61B5/150824 , A61B5/150862 , A61B5/150969 , A61B5/15126 , A61B5/15146 , A61B5/15153 , A61B5/157

59. 发明公开

EP1676591A3 Compositions and methods to create a vascularized environment for cellular transplantation 审中-公开
标题翻译：组合物和方法用于制备血管环境的细胞移植
公开(公告)号：EP1676591A3
公开(公告)日：2006-09-06
申请号：EP05257209.6
申请日：2005-11-23
申请人： LifeScan, Inc.
发明人： Rezania, Alireza , Xu, Jean , Ghabrial, Ragae
IPC分类号： A61L27/54 , A61L27/34 , A61L27/38 , A61L27/56
CPC分类号： A61L27/54 , A61L27/36 , A61L27/38 , A61L27/58 , A61L2300/252 , A61L2300/402 , A61L2300/41 , A61L2300/414 , A61L2300/604
摘要： The present invention generally relates to biocompatible devices suitable for increasing cellular HIF-1 α protein levels. In particular, the present invention relates to an implant comprising a biocompatible support loaded with at least one pharmaceutical agent capable of increasing cellular HIF-1 α protein levels to promote vascularization at or near the implant site. Vascularization of the implanted support results in enhanced survival of cells optionally incorporated within the support. Methods for treating a disease or injury via implanting the support of the present invention are also provided.
摘要翻译：本发明基因的反弹涉及适用于增加细胞HIF-1±蛋白水平的生物相容设备。特别地，本发明涉及一种植入物，其包括在装载有至少一种能够增加细胞HIF-1±蛋白水平处于或植入部位附近，以促进血管形成的药剂的生物相容性支持。在细胞的存活增强植入支撑结果的血管形成在载体内可选地并入。因此，提供用于通过植入本发明的支撑治疗疾病或损伤的方法。

60. 发明授权

EP1368649B1 ELECTROCHEMICAL TEST STRIP CARDS THAT INCLUDE AN INTEGRAL DESSICANT 有权
标题翻译：电化学测试条挑明内置干燥剂CONTAIN
公开(公告)号：EP1368649B1
公开(公告)日：2006-08-23
申请号：EP01271562.9
申请日：2001-12-06
申请人： LifeScan, Inc.
发明人： MATZINGER, David Parkes
IPC分类号： G01N33/52
CPC分类号： C12Q1/004 , G01N33/48778 , Y10T29/49002 , Y10T156/1056 , Y10T156/1057 , Y10T156/1062 , Y10T156/1309
摘要： Electrochemical test strip cards that can be singulated to produce electrochemical test strips are provided. The electrochemical test cards are made up of two or more electrochemical test strip precursors, where each precursor is characterized by the presence of a dry reagent housing reaction chamber bounded by opposing electrodes. In gaseous communication with each reaction chamber of the card is an integrated desiccant. Also provided are methods of using the subject electrochemical test strips cards, as well as kits that include the same. The subject test strips and cards find use in the detection/concentration determination of a number of different analytes, including glucose.

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