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41. 发明公开

EP2770930A1 CRYOGENIC BALLOON DEVICE WITH RADIOFREQUENCY TIP 有权
标题翻译：无线射频PEAK低温气圈装置
公开(公告)号：EP2770930A1
公开(公告)日：2014-09-03
申请号：EP12843951.0
申请日：2012-10-19
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre
IPC分类号： A61B18/02 , A61B18/12 , A61N1/30 , A61N1/40
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00357 , A61B2018/00375 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00863 , A61B2018/00898 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

42. 发明公开

EP2688500A4 SPRAY NOZZLE DESIGN FOR CATHETER 有权
标题翻译：草案喷嘴用于导管
公开(公告)号：EP2688500A4
公开(公告)日：2014-08-20
申请号：EP12763944
申请日：2012-03-16
申请人： MEDTRONIC CRYOCATH LP
发明人： LALONDE JEAN-PIERRE
IPC分类号： A61B18/02 , A61B18/00 , A61M25/14 , B05B1/00
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.

43. 发明公开

EP2632371A1 COMPATIBLE CRYOGENIC COOLING SYSTEM 有权
标题翻译：兼容低的温度冷却系统
公开(公告)号：EP2632371A1
公开(公告)日：2013-09-04
申请号：EP11835372.1
申请日：2011-09-15
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre
IPC分类号： A61B18/02 , F25B25/02 , F25B40/02
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00577 , A61B2018/0212 , A61B2018/0237 , A61B2018/0262
摘要： A method of operating a medical system, including coupling a medical system to an outlet of a fluid distribution network having a plurality of fluid outlets in a patient treatment center; delivering fluid from the outlet to the medical system; compressing the delivered fluid with the medical system; decreasing the moisture content of the delivered fluid with the medical system; cooling the fluid with the medical system; delivering the fluid from the medical system to a medical device; and removing the fluid from medical device with the medical system.

44. 发明公开

EP2528647A1 MULTIFUNCTIONAL ABLATION DEVICE 无效
标题翻译：多功能消融
公开(公告)号：EP2528647A1
公开(公告)日：2012-12-05
申请号：EP11736557.7
申请日：2011-01-21
申请人： Medtronic Cryocath LP
发明人： PAGEARD, Jean-Luc
IPC分类号： A61M25/01 , A61B18/02 , A61B18/08 , A61M25/098 , A61M25/10
CPC分类号： A61B18/02 , A61B18/1492 , A61B90/39 , A61B2018/00023 , A61B2018/00041 , A61B2018/00214 , A61B2018/0022 , A61B2018/00255 , A61B2018/00285 , A61B2018/00351 , A61B2018/00357 , A61B2018/00375 , A61B2018/00577 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.

45. 发明授权

EP1977781B1 Defined deflection structure 有权
标题翻译：定义偏转
公开(公告)号：EP1977781B1
公开(公告)日：2012-11-07
申请号：EP08011930.8
申请日：2002-09-25
申请人： MEDTRONIC CRYOCATH LP
发明人： Carroll, Sean , Santoianni, Domenic , Thibault, Benoit , Wittenberger, Dan , Aubert, Mathieu-Philippe , Marcotte, Marc-Andre
IPC分类号： A61M25/01 , A61M25/00
CPC分类号： A61M25/0105 , A61B1/0051 , A61B18/1492 , A61B2018/00214 , A61B2018/00898 , A61M25/0041 , A61M25/0043 , A61M25/005 , A61M25/0054 , A61M25/0116 , A61M25/0138 , A61M25/0141 , A61M25/0144 , A61M25/0147 , A61M25/0155 , A61M25/0662 , A61M25/10 , A61M2025/0161 , A61M2025/0163 , A61M2025/09141

46. 发明公开

EP2512329A1 VEIN OCCLUSION DEVICES AND METHODS FOR CATHETER-BASED ABLATION 有权
标题翻译： VENENVERSCHLUSSVORRICHTUNGENFÜRKATHETERBASIERTE ABLATION
公开(公告)号：EP2512329A1
公开(公告)日：2012-10-24
申请号：EP10795866.2
申请日：2010-12-10
申请人： MEDTRONIC CRYOCATH LP
发明人： PAGEARD, Jean-Luc , MIHALIK, Teresa, A.
IPC分类号： A61B5/0215 , A61B5/026 , A61M25/00 , A61M25/10 , A61B17/12 , A61B17/00 , A61B18/00 , A61B18/14 , A61B18/02
CPC分类号： A61B5/02158 , A61B5/026 , A61B5/04085 , A61B5/6853 , A61B5/6869 , A61B5/6885 , A61B18/14 , A61B2017/00039 , A61B2017/00084 , A61B2017/00243 , A61B2017/22067 , A61B2018/00011 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61M2025/1052 , A61M2025/1086
摘要： Medical devices and methods for deriving an indication of occlusion of a blood vessel from one or more physiologic sensor are disclosed. The physiological parameters contemplated for implementation in accordance with embodiments of the disclosure may include pressure, flow, force, temperature, or tension. An exemplary device comprises a catheter having an expandable chamber coupled to a distal end portion of the catheter shaft. In various embodiments, one or more physiologic sensors may be disposed on the catheter shaft and electrically coupled to control electronics that may be provided in a console for measurement of a physiologic signal. Alternatively, an external sensor may be disposed in fluid communication with a lumen of the catheter to derive a physiological parameter such as pressure via mechanical coupling of pressure distal to the expandable chamber to the fluid in the lumen. The parameters measured by the physiologic sensor(s) provide a measure of the physiological parameters in at least a first region. The physiological parameter measured in the first region is evaluated to obtain an indication of occlusion distal to the expandable chamber. In other embodiments, measurements of the physiological parameters may be performed in the first region and a second region to derive differential measurements that are evaluated to obtain an indication of occlusion.
摘要翻译：公开了用于从一个或多个生理传感器导出血管闭塞指示的医疗装置和方法。根据本公开的实施例预期实施的生理参数可以包括压力，流量，力，温度或张力。示例性装置包括具有联接到导管轴的远端部分的可扩张腔的导管。在各种实施例中，一个或多个生理传感器可以设置在导管轴上并且电耦合到可以设置在控制台中用于测量生理信号的控制电子装置。或者，可以将外部传感器设置成与导管的内腔流体连通，以通过机械耦合远离可扩张腔的腔内腔内的流体来产生生理参数，例如压力。由生理传感器测量的参数提供至少第一区域中的生理参数的度量。评估在第一区域中测量的生理参数，以获得可扩展腔远端的闭塞指示。在其他实施例中，生理参数的测量可以在第一区域和第二区域中进行，以得到被评估以获得闭塞指示的差异测量值。

47. 发明公开

EP2470254A1 VARIABLE GEOMETRY BALLOON CATHETER AND METHOD 无效
标题翻译：具有可调几何和程序球囊导管
公开(公告)号：EP2470254A1
公开(公告)日：2012-07-04
申请号：EP10825889.8
申请日：2010-10-25
申请人： Medtronic Cryocath LP
发明人： WITTENBERGER, Dan , ABBOUD, Marwan , DEAC, Iona, Alina
IPC分类号： A61M25/10
CPC分类号： A61B18/02 , A61B2017/00256 , A61B2017/00867 , A61B2017/22051 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61M25/1002 , A61M29/02 , A61M2029/025
摘要： A medical device is provided that may include a catheter body having proximal and distal portions, a fluid injection lumen disposed within elongate body, and a guidewire lumen disposed within the elongate body. A tip portion defining a cavity in fluid communication with the fluid injection lumen may be coupled to the distal end of the guidewire lumen, and an expandable element may be coupled to the distal portion of the catheter body and to the tip portion, such that the expandable element is in fluid communication with the fluid injection lumen. A shaping element may at least partially surround the expandable element, where the shaping element is configurable in a first geometric configuration and a second geometric configuration.

48. 发明公开

EP2467107A1 CRYOTREATMENT DEVICE USING A SUPERCRITICAL GAS 有权
标题翻译：美国伊朗伊斯兰共和国
公开(公告)号：EP2467107A1
公开(公告)日：2012-06-27
申请号：EP10813187.1
申请日：2010-08-16
申请人： MEDTRONIC CRYOCATH LP
发明人： LALONDE, Jean-Pierre
IPC分类号： A61F7/00 , A61B1/12 , A61F7/12 , A61M5/44 , C09K5/04
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A method of cryogenically treating a tissue region is provided, including positioning a treatment region of a medical device proximate the tissue region; transferring coolant in a substantially liquid phase from a coolant reservoir to a subcooler; transitioning the coolant from the liquid phase into a supercritical state; transferring the supercritical coolant to the treatment region; changing the coolant from the supercritical state to at least one of a liquid phase and a gaseous phase at the treatment region; ablating the tissue region; and evacuating coolant from the treatment region of the medical device.
摘要翻译：提供了一种低温处理组织区域的方法，包括将医疗装置的治疗区域定位在组织区域附近; 将基本上液相的冷却剂从冷却剂贮存器传送到过冷却器; 将冷却剂从液相转变为超临界状态; 将超临界冷却剂转移到处理区域; 在处理区域将冷却剂从超临界状态改变为液相和气相中的至少一种; 烧蚀组织区域; 并从医疗装置的处理区域排出冷却剂。

49. 发明公开

EP2294490A4 THERMOCOUPLE-CONTROLLED CATHETER COOLING SYSTEM 有权
标题翻译： BY热电偶控制的导管冷却系统
公开(公告)号：EP2294490A4
公开(公告)日：2012-03-07
申请号：EP09745339
申请日：2009-05-14
申请人： MEDTRONIC CRYOCATH LP
发明人： LALONDE JEAN-PIERRE , WITTENBERGER DAN , ABBOUD MARWAN , CIOBOTARU CONSTANTIN BOGDAN , SABBAGHE-KERMANI RAMIN
IPC分类号： G05D7/00 , A61B18/00 , A61B18/02 , A61F7/12 , A61M25/00 , G01M3/00 , G01M3/40
CPC分类号： A61B18/02 , A61B2018/00023 , A61B2018/0022 , A61B2018/00797 , A61B2018/00821 , A61B2018/0212 , A61B2018/0262 , A61M25/0136
摘要： The present invention provides a medical system, including a catheter defining an injection lumen, a chamber in fluid communication with the injection lumen, and an exhaust lumen in fluid communication with the chamber; a first temperature sensor positioned in the exhaust lumen proximal to the chamber; a second temperature sensor positioned in the chamber; and a console in electrical communication with the first and second temperature sensors, the controller modifying coolant flow through the medical device based at least in part upon a signal received from the first and second temperature sensor. The system may further include a thermally-conductive element circumscribing a substantial portion of the exhaust lumen proximal to the chamber, where the first temperature sensor is mounted to the thermally-conductive element, and the thermally-conductive element may include at least one of a braid, coil, and band.

50. 发明授权

EP1871258B1 FLUID CONTROL SYSTEM FOR A MEDICAL DEVICE 有权转让
标题翻译：流动控制系统的医疗器械
公开(公告)号：EP1871258B1
公开(公告)日：2010-08-25
申请号：EP06720345.5
申请日：2006-02-06
申请人： MEDTRONIC CRYOCATH LP
发明人： LEHMANN, John, W. , ABBOUD, Marwan , MAHROUCHE, Rachid , MIHALIK, Teresa, Ann , HARMOUCHE, Chadi , PAGEARD, Jean-Luc
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00084 , A61B2018/0022 , A61B2018/00577 , A61B2018/00744 , A61B2018/00863 , A61B2018/00898 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , G01M3/02 , G01M3/2846
摘要： The present invention provides a medical device having an elongate body with both a proximal end and a distal end, wherein the elongate body defines an intake lumen and an exhaust lumen. The medical device also has a first pliable element defining a cooling chamber disposed at a point along the elongate body, with the cooling chamber being in fluid communication with the intake lumen and the exhaust lumen. A second pliable element is provided which at least partially encloses the first pliable element, thereby defining a junction between the first and second pliable element. Moreover, a check valve is included which is in fluid communication with the junction between the first pliable element and second pliable element, the valve further being in fluid communication with the exhaust lumen. In addition, the medical device may include sensors or other monitoring means in fluid communication with the junction and the cooling chamber.

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