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31. 发明公开

EP2124844A1 ENDOPROSTHESES INCLUDING METAL MATRIX COMPOSITE STRUCTURES 审中-公开
标题翻译：金属基复合材料结构内假体
公开(公告)号：EP2124844A1
公开(公告)日：2009-12-02
申请号：EP08729055.7
申请日：2008-02-05
申请人： Boston Scientific Limited
发明人： STINSON, Jonathan S.
IPC分类号： A61F2/82 , A61L31/12
CPC分类号： C22C1/045 , A61F2/0077 , A61F2/91 , A61F2210/0076 , A61F2230/0054 , A61L31/088 , A61L31/124 , B22F2998/00 , B22F2999/00 , Y10T29/49801 , B22F1/02 , C22C1/101 , B22F3/02 , B22F3/10 , B22F3/15 , B22F3/20
摘要： An endoprosthesis that includes a composite having a metal matrix and a plurality of stiffening particles in the matrix. The metal of the metal matrix can include titanium, niobium, tantalum, or alloys thereof. The stiffening particles can include a metal core and a thin surface layer. The thin surface layer can include oxides, carbides, nitrides, or combinations thereof.

32. 发明公开

EP1721625A3 Biodegradable medical devices with enhanced mechanical strength and pharmacological functions 失效转让
标题翻译：具有改进的机械强度和药理作用的可生物降解的医疗设备
公开(公告)号：EP1721625A3
公开(公告)日：2008-11-05
申请号：EP06250728.0
申请日：2006-02-10
申请人： Cordis Corporation
发明人： Zhao, Jonathon
IPC分类号： A61L31/10 , A61L31/08 , A61K31/06 , A61K31/02 , A61K31/12
CPC分类号： A61K31/02 , A61K31/06 , A61K31/12 , A61L31/08 , A61L31/10 , A61L31/124 , A61L31/128 , A61L2420/04 , C08L67/04
摘要： The present invention is directed to a medical device, specifically a prosthesis which utilizes a novel class of blends between biodegradable polymers and biocerannics for medical device applications allowing one to capitalize on the biodegradable nature of these two distinct materials while enhancing the strength of these devices through the addition of various amounts ofbioactive ceramic and glasses to biodegradable polymers. The blend may be fabricated into a medical device such as a stent or a distal protection device, and may incorporate various agents to enhance radioapacity and/or pharmacological function-In addition, the blend may be used as a coating to a medical device.
In one embodiment a medical device comprises a biodegradable polymer in the form of particles; and a bioactive ceramic in the form of particles wherein the combination of biodegradable polymer particles and bioactive ceramic particles arc blended together.

33. 发明公开

EP1898837A1 ENDOPROSTHESES 审中-公开
标题翻译：用假体
公开(公告)号：EP1898837A1
公开(公告)日：2008-03-19
申请号：EP06759439.0
申请日：2006-05-08
申请人： Boston Scientific Scimed, Inc.
发明人： WEBER, Jan
IPC分类号： A61F2/06 , A61L31/18
CPC分类号： A61L31/18 , A61B6/12 , A61B90/39 , A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/91558 , A61F2230/0013 , A61L31/082 , A61L31/124
摘要： Medical devices, such as endoprostheses, are disclosed. In some embodiments, an endoprosthesis includes a tubular body including a first material having a first mass attenuation coefficient; and a coating (24) on less than or equal to half of a (e.g., any) circumferential cross section occupied by the body. The coating includes a second material having a second mass attenuation coefficient greater than the first mass attenuation coefficient. When placed in a body, the endoprosthesis can be imaged using multiple types of methods, such as computed tomography.

34. 发明公开

EP1893780A2 METAL ALLOY FOR A STENT 有权转让
标题翻译：合金用于支架
公开(公告)号：EP1893780A2
公开(公告)日：2008-03-05
申请号：EP06717618.0
申请日：2006-01-06
申请人： Icon Interventional Systems, Inc.
发明人： FURST, Joseph, G. , BUCKMAN, Raymond, W., Jr. , PATEL, Udayan
IPC分类号： C22C27/00 , A61F2/06 , C22C27/04
CPC分类号： A61L31/022 , A61L31/124 , A61L31/18 , C22C27/00 , C22C27/04 , C22C30/00
摘要： A stent that is at least partially formed of a novel metal alloy, which novel metal alloy improves the physical properties of the stent.

35. 发明授权

EP1866453B1 METAL ALLOY FOR MEDICAL DEVICE 有权转让
公开(公告)号：EP1866453B1
公开(公告)日：2024-05-01
申请号：EP06717846.7
申请日：2006-01-09
IPC分类号： C22C27/00 , C22C30/00 , C22C27/04 , A61L31/18 , A61L31/02 , A61L31/12
CPC分类号： A61L31/022 , A61L31/124 , A61L31/18 , C22C27/00 , C22C27/04 , C22C30/00

36. 发明公开

EP3322454A1 COMPOSITE MATERIAL FOR IMPLANTS, ITS USE AND METHOD OF ITS PRODUCTION 有权
公开(公告)号：EP3322454A1
公开(公告)日：2018-05-23
申请号：EP16763311.4
申请日：2016-07-14
申请人： Ústav Materiálov A Mechaniky Strojov SAV
发明人： BALOG, Martin , CATIC, Amir , KRÍZIK, Peter , SCHAUPERL, Zdravko
IPC分类号： A61L27/06 , A61L27/42 , A61L27/58 , A61L31/02 , A61L31/12 , A61L31/14 , A61K6/04
CPC分类号： A61L27/06 , A61K6/0032 , A61K6/0044 , A61K6/04 , A61L27/427 , A61L27/58 , A61L31/022 , A61L31/124 , A61L31/148
摘要： The composite material comprises a biocompatible titanium (Ti) or biocompatible Ti alloy, and biodegradable component, which is intended to at least partially desorb in vivo in contact with human tissue and which has an Young's elastic modulus lower than used Ti or Ti alloy. The material is prepared from a mixture of the particles of Ti or Ti alloy and the particles of the biodegradable component, wherein the biodegradable component, in particular magnesium (Mg), is dispersed throughout a volume of the material and occupies 2 to 20 volumic % in the material. The biodegradable component is present in a bearing Ti or Ti alloy structure in the form of filaments oriented along an extrusion axis. A manufacturing process comprises fabrication of powders, mechanical blending of powders to a homogeneous mixture and a subsequent extrusion at a temperature from 300 °C to 640 °C. The components are consolidated to a common mass, wherein during a consolidation the biodegradable component is formed into filaments oriented along an extrusion direction. Prior heated and extrusion the powder mixture may be precompacted in order to reach acceptable handling strength and cohesion.

37. 发明公开

EP2956181A4 BIODEGRADABLE METALLIC MEDICAL IMPLANTS, METHOD FOR PREPARING AND USE THEREOF 有权转让
标题翻译：可生物降解，金属医疗植入物，方法生产及其用途
公开(公告)号：EP2956181A4
公开(公告)日：2016-08-31
申请号：EP14751068
申请日：2014-01-09
申请人： BAKER HUGHES INC
发明人： XU ZHIYUE
IPC分类号： A61L27/04 , A61B17/00 , A61B17/68 , A61F2/02 , A61L17/06 , A61L27/02 , A61L27/42 , A61L27/58 , A61L31/12 , A61L31/14
CPC分类号： A61F2/02 , A61B17/68 , A61B2017/00004 , A61F2210/0004 , A61L17/06 , A61L27/427 , A61L27/58 , A61L31/124 , A61L31/148 , A61L2400/12
摘要： A medical implant includes a metal composite that contains a cellular nanomatrix having a metallic nanomatrix material and a metal matrix disposed in the cellular nanomatrix, the medical implant being configured to disintegrate in response to contact with a fluid. A method for repairing tissue includes disposing an implant in a patient, the implant including a metal composite which contains: a cellular nanomatrix having a metallic nanomatrix material; and a metal matrix disposed in the cellular nanomatrix; contacting tissue of the patient with the implant, the tissue being in need of repair; and non-operatively removing the implant to repair the tissue.
摘要翻译：一种医用植入物包括金属复合确实含有具有金属纳米基质材料和在蜂窝纳米矩阵布置在金属基体中的蜂窝纳米矩阵，所述医疗植入物被构造成响应于崩解与流体接触。一种用于修复组织的方法包括在患者中的植入物的放置，植入物包括其中含有金属复合：具有金属纳米基质材料中的蜂窝纳米矩阵; 和金属基体设置在所述蜂窝纳米矩阵; 联系与植入患者的组织，该组织需要修复的是; 和非操作地去除所述植入物以修复组织。

38. 发明公开

EP2716777A4 COMPOSITE MATERIAL FOR MEDICAL DEVICES AND METHOD FOR PRODUCING SAME 有权
标题翻译：复合材料用于医疗设备及其制造方法
公开(公告)号：EP2716777A4
公开(公告)日：2015-12-16
申请号：EP12790246
申请日：2012-05-08
申请人： TERUMO CORP
发明人： SOBA RYOICHI
IPC分类号： C22C1/10 , A61B17/12 , A61C7/20 , A61F2/01 , A61F2/82 , A61L31/12 , A61L31/14 , A61M25/09 , B22F3/20 , C22C32/00
CPC分类号： A61F2/013 , A61B17/12113 , A61C7/20 , A61F2/82 , A61L31/124 , A61L31/14 , A61L2400/16 , A61L2430/36 , A61M25/09 , B22F3/20 , B22F2998/10 , C22C1/10 , C22C32/001 , C22C32/0021 , C22C32/0026 , C22C32/0031 , B22F9/04 , C22C1/05 , B22F3/10
摘要： A composite material for medical devices includes a superelastic shape memory alloy which configures a matrix and a metal oxide which is dispersed in the matrix.

39. 发明公开

EP2363156A2 Method of fabricating biodegradable medical devices with enhanced mechanical strength and pharmacological functions 审中-公开
标题翻译： Bioabbaubare medizinische Vorrichtungen mit verbesserter mechanischer Festigkeit und pharmakologischer Funktion
公开(公告)号：EP2363156A2
公开(公告)日：2011-09-07
申请号：EP11162789.9
申请日：2006-02-10
申请人： Cordis Corporation
发明人： Zhao, Jonathon
IPC分类号： A61L31/10 , A61L31/08 , A61K31/06 , A61K31/02 , A61K31/12
CPC分类号： A61K31/02 , A61K31/06 , A61K31/12 , A61L31/08 , A61L31/10 , A61L31/124 , A61L31/128 , A61L2420/04 , C08L67/04
摘要： The present invention is directed to a medical device, specifically a prosthesis which utilizes a novel class of blends between biodegradable polymers and bioceramics for medical device applications allowing one to capitalize on the biodegradable nature of these two distinct materials while enhancing the strength of these devices through the addition of various amounts of bioactive ceramic and glasses to biodegradable polymers. The blend may be fabricated into a medical device such as a stent or a distal protection device, and may incorporate various agents to enhance radioapacity and/or pharmacological function. In addition, the blend may be used as a coating to a medical device.
In one embodiment a method to fabricate a stent or distal protection device comprises the steps of:
blending a biodegradable polymer solution with bioactive ceramic particles to create a material; and either
forming said material into a desired shape for a stent or a distal protection device application; or
applying said material as a coating material to encapsulate a stent or distal protection device.
摘要翻译：本发明涉及一种医疗装置，特别是一种假体，其利用可生物降解的聚合物和用于医疗装置应用的生物陶瓷之间的新一类共混物，允许利用这两种不同材料的可生物降解性质，同时增强这些装置的强度向可生物降解的聚合物中加入各种量的生物活性陶瓷和玻璃。共混物可以制造成诸如支架或远端保护装置的医疗装置，并且可以结合各种试剂以增强放射性能力和/或药理功能。此外，共混物可以用作医疗装置的涂层。在一个实施方案中，制造支架或远端保护装置的方法包括以下步骤：将可生物降解的聚合物溶液与生物活性陶瓷颗粒混合以产生材料; 并且将所述材料形成为用于支架或远端保护装置应用的期望形状; 或施加所述材料作为涂层材料以包封支架或远端保护装置。

40. 发明公开

EP1765219A4 MEDICAL DEVICES COMPOSED OF POROUS METALLIC MATERIALS FOR DELIVERING BIOLGICALLY ACTIVE MATERIALS 审中-公开
标题翻译：医疗用品由多孔金属材料作生物分布活性物质
公开(公告)号：EP1765219A4
公开(公告)日：2010-11-24
申请号：EP05754639
申请日：2005-05-26
申请人： BOSTON SCIENT LTD
发明人： GERBERDING BRENT
IPC分类号： A61F2/02 , A61K31/337 , A61K31/4745 , A61K38/18 , A61L31/08 , A61L31/12 , A61L31/14 , A61L31/16 , A61L31/18
CPC分类号： A61K31/4745 , A61K31/337 , A61L31/082 , A61L31/088 , A61L31/124 , A61L31/146 , A61L31/16 , A61L31/18 , A61L2300/606

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