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31. 发明授权

EP3062721B1 FEEDBACK SYSTEM FOR CRYOABLATION OF CARDIAC TISSUE 有权
公开(公告)号：EP3062721B1
公开(公告)日：2019-03-27
申请号：EP14858556.5
申请日：2014-10-27
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre , GROVES, Regina E. , LASKE, Timothy G. , IAIZZO, Paul A. , BISCHOF, John C.
IPC分类号： A61B18/02 , A61B18/14

32. 发明授权

EP2629834B1 BALLOON CATHETER WITH DEFORMABLE FLUID DELIVERY CONDUIT 失效
公开(公告)号：EP2629834B1
公开(公告)日：2018-10-31
申请号：EP11833661.9
申请日：2011-09-13
申请人： Medtronic Cryocath LP
发明人： WITTENBERGER, Dan
IPC分类号： A61B18/02 , A61M25/01 , A61M25/14 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/0022 , A61B2018/00345 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212 , A61B2018/0268 , A61M25/0147
摘要： A medical device, including an elongate body having a proximal portion and a distal portion; a shaft at least partially disposed within the elongate body; an expandable element at the distal portion of the elongate body; and a fluid delivery conduit defining a deflectable segment movably coupled to the shaft, the deflectable segment being transitionable from a substantially linear configuration to a substantially curvilinear configuration.

33. 发明公开

EP3364857A1 POST ABLATION TISSUE ANALYSIS TECHNIQUE 无效
公开(公告)号：EP3364857A1
公开(公告)日：2018-08-29
申请号：EP16856519.0
申请日：2016-10-18
申请人： Medtronic Cryocath LP
发明人： SARA, Rahmani
IPC分类号： A61B5/00 , A61B18/02 , A61B90/00
CPC分类号： A61B18/02 , A61B5/0075 , A61B5/0084 , A61B5/0535 , A61B5/0538 , A61B5/4836 , A61B18/1492 , A61B2017/00061 , A61B2018/0022 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00755 , A61B2018/00839 , A61B2018/00875 , A61B2018/0212
摘要： A device, system, and method for identifying an area of ablated tissue. Specifically, the device, system, and method may include a device having one or more fiber sensors and a processing unit for receiving emitted and/or reflected light from tissue and making one or more determinations based on the received light regarding ablated tissue, tissue contact, and/or occlusion. Each of the fiber sensors may include at least one multimode waveguide segment and at least one singlemode waveguide segment, or each of the fiber sensors may be singlemode waveguide. Further, each fiber sensor may have a core with long-period grating for optically coupling light from tissue to the fiber sensor. The processing unit may include a beam processing apparatus and a hyperspectral imaging and analysis apparatus, and may optionally include a light source.

34. 发明公开

EP3166523A4 CRYOABLATION METHOD AND SYSTEM 有权
公开(公告)号：EP3166523A4
公开(公告)日：2018-03-14
申请号：EP15818849
申请日：2015-06-15
申请人： MEDTRONIC CRYOCATH LP
发明人： MAHROUCHE RACHID , WITTENBERGER DAN
IPC分类号： A61B18/02 , A61M39/22
CPC分类号： A61B18/02 , A61B2018/00011 , A61B2018/00017 , A61B2018/00023 , A61B2018/00041 , A61B2018/0022 , A61B2018/00577 , A61B2018/0212 , A61B2018/0268
摘要： A system and method for providing greater control over the temperature of a thermal treatment element of a medical device, enabling an operator to extend a thawing period of a cryoablation procedure. The system may include a fluid flow path that bypasses a subcooler, giving the operator selective control over the temperature of refrigerant delivered to the treatment element and, therefore, treatment element temperature. Additionally or alternatively, the system may include a fluid delivery conduit that is in communication with a liquid refrigerant and a gaseous refrigerant. Adjustment of the ratio of liquid to gaseous refrigerant also offers control over the treatment element temperature. Additionally or alternatively, the system may include one or more valves and/or heating elements in the fluid delivery and recovery conduits to control the treatment element temperature.

35. 发明授权

EP2528528B1 CRYOBALLOON REFRIGERANT DISPERSION CONTROL 有权
标题翻译： CRYOBALLOON制冷剂分散控制
公开(公告)号：EP2528528B1
公开(公告)日：2018-03-07
申请号：EP11736581.7
申请日：2011-01-27
申请人： Medtronic Cryocath LP
发明人： DESROCHERS, Gilles
IPC分类号： A61B18/02 , A61M25/10 , A61B17/00
CPC分类号： A61B18/02 , A61B18/0218 , A61B2017/003 , A61B2018/0022 , A61B2018/00255 , A61B2018/0212 , A61B2018/0262 , A61B2090/065 , A61M25/0069 , A61M25/1011 , A61M2025/0079 , A61M2025/1088 , A61M2025/1093
摘要： A catheter based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. An open distal end or one or more orifices may be provided on the injection tube for the refrigerant to be expelled into an expandable chamber such as a balloon disposed on the distal portion of the catheter. The dispersion of the refrigerant from the injection tube may be controlled or manipulable to direct the refrigerant to one or more target locations.

36. 发明公开

EP3209365A1 CENTERING COILED GUIDE 审中-公开
标题翻译：居中线圈指南
公开(公告)号：EP3209365A1
公开(公告)日：2017-08-30
申请号：EP15853073.3
申请日：2015-10-20
申请人： Medtronic Cryocath LP
发明人： DEAC, Ioana
IPC分类号： A61M25/09 , A61M25/14
CPC分类号： A61M25/0147 , A61B18/00 , A61M25/0043 , A61M25/0144 , A61M2025/0059
摘要： A device and system for providing a centered lumen within a catheter body. A coiled guide lumen (CGL) is composed of a length of wire forming a plurality of coils about the longitudinal axis of the CGL, the CGL including one or more first sections having a first diameter and one or more sections having a second diameter, the second diameter being greater than the first diameter, and a secondary guide lumen extending through the first sections. The CGL may include at least one pull wire extending through the secondary guide lumen and attached at the distal portion of the catheter body. A band may be coupled to an interior of the catheter body distal portion, each of the pull wires being coupled to the annular band. Alternatively, the system may further include a shim coupled to the band, each of the pulls wire being coupled to the shim.
摘要翻译：一种用于在导管体内提供中心内腔的装置和系统。盘绕的引导管腔（CGL）由一定长度的线材形成，所述线材围绕CGL的纵向轴线形成多个线圈，所述CGL包括具有第一直径的一个或多个第一部分和具有第二直径的一个或多个部分，所述第二直径大于第一直径，以及延伸穿过第一部分的第二引导腔。 CGL可以包括至少一根拉线，该拉线延伸穿过第二引导腔并且附接在导管主体的远端部分。带可以联接到导管主体远侧部分的内部，每个拉线联接到环形带。或者，该系统还可以包括耦合到带的垫片，每个拉线耦合到垫片。

37. 发明公开

EP2600787A4 CRYOGENIC MEDICAL MAPPING AND TREATMENT DEVICE 审中-公开
标题翻译： KRYOGENE MEDIZINISCHE ABBILDUNGS- UND BEHANDLUNGSVORRICHTUNG
公开(公告)号：EP2600787A4
公开(公告)日：2017-08-16
申请号：EP11813976
申请日：2011-07-20
申请人： MEDTRONIC CRYOCATH LP
发明人： WITTENBERGER DAN
IPC分类号： A61B18/02 , A61B5/02 , A61B5/046 , A61B18/14 , A61F2/958 , A61M25/10
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00375 , A61B2018/00839 , A61B2018/0212 , A61B2018/1497
摘要： A medical device and method are provided for mapping and therapeutic treatment, which may include a source of cryogenic fluid, a balloon or other expandable member in fluid communication with the source of cryogenic fluid, and a plurality of electrodes on the expandable member. The medical device may include a catheter or elongate body, and the electrodes may take the form of longitudinal strips. The expandable member may take the form of an inner and outer balloon, and the electrodes may be on the outer balloon. The electrodes may be on a proximal or distal conical portion of the expandable member, or both. An electrical insulator may be provided covering a portion of the electrodes.
摘要翻译：提供用于测绘和治疗处理的医疗装置和方法，其可以包括低温流体源，与低温流体源流体连通的球囊或其他可膨胀构件以及可膨胀构件上的多个电极。医疗装置可以包括导管或细长主体，并且电极可以采取纵向条的形式。可膨胀元件可以采取内部和外部气囊的形式，并且电极可以在外部气囊上。电极可以位于可扩张构件的近侧或远侧锥形部分上，或者两者。可以提供覆盖电极的一部分的电绝缘体。

38. 发明公开

EP2528527A4 PARTIALLY COMPLIANT BALLOON DEVICE 审中-公开
标题翻译：部分符合气囊装置
公开(公告)号：EP2528527A4
公开(公告)日：2016-12-28
申请号：EP11736556
申请日：2011-01-21
申请人： MEDTRONIC CRYOCATH LP
发明人： WITTENBERGER DAN
IPC分类号： A61B18/02 , A61F2/958 , A61M25/10
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00375 , A61B2018/0212
摘要： A medical device is provided, having an elongate body defining a distal portion and a proximal portion; a first expandable member disposed on the distal portion of the elongate body and defining a cooling chamber therein, the first expandable member having a first rigidity; a second expandable member disposed around the first expandable member to define an interstitial region therebetween, where the second expandable member has a second rigidity less than the first rigidity; a gel disposed within the interstitial region; a coolant flow path in fluid communication with the cooling chamber; and a cryogenic coolant source in fluid communication with the coolant flow path.

39. 发明公开

EP2528526A4 TRIPLE BALLOON CATHETER 无效
标题翻译： TRIPLE球囊导管
公开(公告)号：EP2528526A4
公开(公告)日：2016-12-28
申请号：EP11736555
申请日：2011-01-21
申请人： MEDTRONIC CRYOCATH LP
发明人： PAGEARD JEAN-LUC
IPC分类号： A61B18/02 , A61F2/958 , A61M25/10
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212
摘要： The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.

40. 发明公开

EP2771055A1 SYSTEMS AND METHODS FOR VARIABLE INJECTION FLOW 有权
标题翻译：系统和可变注射流方法
公开(公告)号：EP2771055A1
公开(公告)日：2014-09-03
申请号：EP12788671.1
申请日：2012-10-18
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre , LASKE, Timothy G. , LUECKGE, Claudia , WITTENBERGER, Dan , SABBAGHE-KERMANI, Ramin , SERAJ, Mahmoud Kabir
IPC分类号： A61M25/00 , A61B18/02 , A61M39/28
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/00023 , A61B2018/00095 , A61B2018/00101 , A61B2018/00202 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61M25/0029 , A61M25/007 , A61M39/22 , A61M39/28 , A61M2025/0025 , A61M2025/0079 , A61M2025/0175 , Y10T137/0318
摘要： Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.

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