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31. 发明授权

EP2528528B1 CRYOBALLOON REFRIGERANT DISPERSION CONTROL 有权
标题翻译： CRYOBALLOON制冷剂分散控制
公开(公告)号：EP2528528B1
公开(公告)日：2018-03-07
申请号：EP11736581.7
申请日：2011-01-27
申请人： Medtronic Cryocath LP
发明人： DESROCHERS, Gilles
IPC分类号： A61B18/02 , A61M25/10 , A61B17/00
CPC分类号： A61B18/02 , A61B18/0218 , A61B2017/003 , A61B2018/0022 , A61B2018/00255 , A61B2018/0212 , A61B2018/0262 , A61B2090/065 , A61M25/0069 , A61M25/1011 , A61M2025/0079 , A61M2025/1088 , A61M2025/1093
摘要： A catheter based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. An open distal end or one or more orifices may be provided on the injection tube for the refrigerant to be expelled into an expandable chamber such as a balloon disposed on the distal portion of the catheter. The dispersion of the refrigerant from the injection tube may be controlled or manipulable to direct the refrigerant to one or more target locations.

32. 发明公开

EP3209365A1 CENTERING COILED GUIDE 审中-公开
标题翻译：居中线圈指南
公开(公告)号：EP3209365A1
公开(公告)日：2017-08-30
申请号：EP15853073.3
申请日：2015-10-20
申请人： Medtronic Cryocath LP
发明人： DEAC, Ioana
IPC分类号： A61M25/09 , A61M25/14
CPC分类号： A61M25/0147 , A61B18/00 , A61M25/0043 , A61M25/0144 , A61M2025/0059
摘要： A device and system for providing a centered lumen within a catheter body. A coiled guide lumen (CGL) is composed of a length of wire forming a plurality of coils about the longitudinal axis of the CGL, the CGL including one or more first sections having a first diameter and one or more sections having a second diameter, the second diameter being greater than the first diameter, and a secondary guide lumen extending through the first sections. The CGL may include at least one pull wire extending through the secondary guide lumen and attached at the distal portion of the catheter body. A band may be coupled to an interior of the catheter body distal portion, each of the pull wires being coupled to the annular band. Alternatively, the system may further include a shim coupled to the band, each of the pulls wire being coupled to the shim.
摘要翻译：一种用于在导管体内提供中心内腔的装置和系统。盘绕的引导管腔（CGL）由一定长度的线材形成，所述线材围绕CGL的纵向轴线形成多个线圈，所述CGL包括具有第一直径的一个或多个第一部分和具有第二直径的一个或多个部分，所述第二直径大于第一直径，以及延伸穿过第一部分的第二引导腔。 CGL可以包括至少一根拉线，该拉线延伸穿过第二引导腔并且附接在导管主体的远端部分。带可以联接到导管主体远侧部分的内部，每个拉线联接到环形带。或者，该系统还可以包括耦合到带的垫片，每个拉线耦合到垫片。

33. 发明公开

EP2600787A4 CRYOGENIC MEDICAL MAPPING AND TREATMENT DEVICE 审中-公开
标题翻译： KRYOGENE MEDIZINISCHE ABBILDUNGS- UND BEHANDLUNGSVORRICHTUNG
公开(公告)号：EP2600787A4
公开(公告)日：2017-08-16
申请号：EP11813976
申请日：2011-07-20
申请人： MEDTRONIC CRYOCATH LP
发明人： WITTENBERGER DAN
IPC分类号： A61B18/02 , A61B5/02 , A61B5/046 , A61B18/14 , A61F2/958 , A61M25/10
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00375 , A61B2018/00839 , A61B2018/0212 , A61B2018/1497
摘要： A medical device and method are provided for mapping and therapeutic treatment, which may include a source of cryogenic fluid, a balloon or other expandable member in fluid communication with the source of cryogenic fluid, and a plurality of electrodes on the expandable member. The medical device may include a catheter or elongate body, and the electrodes may take the form of longitudinal strips. The expandable member may take the form of an inner and outer balloon, and the electrodes may be on the outer balloon. The electrodes may be on a proximal or distal conical portion of the expandable member, or both. An electrical insulator may be provided covering a portion of the electrodes.
摘要翻译：提供用于测绘和治疗处理的医疗装置和方法，其可以包括低温流体源，与低温流体源流体连通的球囊或其他可膨胀构件以及可膨胀构件上的多个电极。医疗装置可以包括导管或细长主体，并且电极可以采取纵向条的形式。可膨胀元件可以采取内部和外部气囊的形式，并且电极可以在外部气囊上。电极可以位于可扩张构件的近侧或远侧锥形部分上，或者两者。可以提供覆盖电极的一部分的电绝缘体。

34. 发明公开

EP2528527A4 PARTIALLY COMPLIANT BALLOON DEVICE 审中-公开
标题翻译：部分符合气囊装置
公开(公告)号：EP2528527A4
公开(公告)日：2016-12-28
申请号：EP11736556
申请日：2011-01-21
申请人： MEDTRONIC CRYOCATH LP
发明人： WITTENBERGER DAN
IPC分类号： A61B18/02 , A61F2/958 , A61M25/10
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00375 , A61B2018/0212
摘要： A medical device is provided, having an elongate body defining a distal portion and a proximal portion; a first expandable member disposed on the distal portion of the elongate body and defining a cooling chamber therein, the first expandable member having a first rigidity; a second expandable member disposed around the first expandable member to define an interstitial region therebetween, where the second expandable member has a second rigidity less than the first rigidity; a gel disposed within the interstitial region; a coolant flow path in fluid communication with the cooling chamber; and a cryogenic coolant source in fluid communication with the coolant flow path.

35. 发明公开

EP2528526A4 TRIPLE BALLOON CATHETER 无效
标题翻译： TRIPLE球囊导管
公开(公告)号：EP2528526A4
公开(公告)日：2016-12-28
申请号：EP11736555
申请日：2011-01-21
申请人： MEDTRONIC CRYOCATH LP
发明人： PAGEARD JEAN-LUC
IPC分类号： A61B18/02 , A61F2/958 , A61M25/10
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00577 , A61B2018/0212
摘要： The present invention advantageously provides a method and system for cryogenically ablating large areas of tissue within the left atrium. In an exemplary embodiment a cryotherapy device includes a catheter body, a proximal end and a distal end; a first lumen; a second lumen; and an ablation element expandable from a first diameter to a second diameter, the ablation element having a surface portion that conforms to the uneven surface topography of the cardiac tissue. The ablation element can include one or more deformable balloon and/or flexible elements. The surface of the balloon can further be shaped by regulation of pressure within the one or more balloons. In an exemplary method, a tissue ablation device is provided and tissue in the left atrium is ablated with the device, whereby the ablation is created by freezing tissue.

36. 发明公开

EP2771055A1 SYSTEMS AND METHODS FOR VARIABLE INJECTION FLOW 有权
标题翻译：系统和可变注射流方法
公开(公告)号：EP2771055A1
公开(公告)日：2014-09-03
申请号：EP12788671.1
申请日：2012-10-18
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre , LASKE, Timothy G. , LUECKGE, Claudia , WITTENBERGER, Dan , SABBAGHE-KERMANI, Ramin , SERAJ, Mahmoud Kabir
IPC分类号： A61M25/00 , A61B18/02 , A61M39/28
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/00023 , A61B2018/00095 , A61B2018/00101 , A61B2018/00202 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61M25/0029 , A61M25/007 , A61M39/22 , A61M39/28 , A61M2025/0025 , A61M2025/0079 , A61M2025/0175 , Y10T137/0318
摘要： Systems and methods for controllably variable fluid flow are disclosed that provide the ability to modify the effective cross-sectional area of the fluid delivery conduit available for fluid flow. Accordingly, selective control of these configurations allows fluid flow to be regulated as desired while the fluid delivery pressure remains the same. Additional configurations provided herein allow for the selective manipulation of a footprint or therapeutic pattern achievable with the medical device during a single procedure, negating the need for the removal and insertion of multiple devices to achieve the same variations in treatment geometry or characteristics.

37. 发明公开

EP2770930A1 CRYOGENIC BALLOON DEVICE WITH RADIOFREQUENCY TIP 有权
标题翻译：无线射频PEAK低温气圈装置
公开(公告)号：EP2770930A1
公开(公告)日：2014-09-03
申请号：EP12843951.0
申请日：2012-10-19
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre
IPC分类号： A61B18/02 , A61B18/12 , A61N1/30 , A61N1/40
CPC分类号： A61B18/02 , A61B18/1492 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00357 , A61B2018/00375 , A61B2018/00613 , A61B2018/00642 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00863 , A61B2018/00898 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular ablation device, including a flexible elongate body; an expandable element positioned on the elongate body; a radiofrequency or electroporation treatment segment located distally of the expandable element; a cryogenic coolant source in fluid communication with an interior of the expandable element; and a radiofrequency or electroporation energy source in communication with the radiofrequency or electroporation treatment segment.

38. 发明公开

EP2688500A4 SPRAY NOZZLE DESIGN FOR CATHETER 有权
标题翻译：草案喷嘴用于导管
公开(公告)号：EP2688500A4
公开(公告)日：2014-08-20
申请号：EP12763944
申请日：2012-03-16
申请人： MEDTRONIC CRYOCATH LP
发明人： LALONDE JEAN-PIERRE
IPC分类号： A61B18/02 , A61B18/00 , A61M25/14 , B05B1/00
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/00255 , A61B2018/00351 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： A catheter-based medical device including controlled refrigerant dispersion is disclosed. The device includes a fluid injection tube that carries refrigerant from a coolant supply to the distal portion of the device. A fluid dispersion unit is disposed on the distal end of the fluid tube to control the angle of distribution for refrigerant that is expelled from the fluid injection tube. Controlling the angle of distribution for the refrigerant facilitates dispersion of the fluid in a predetermined spray pattern. The disclosure further relates to cryoablation treatment systems incorporating such a catheter, and to cryoablation treatment methods for tissue treatment to address various conditions suitably treatable with cryoablation.

39. 发明公开

EP2632371A1 COMPATIBLE CRYOGENIC COOLING SYSTEM 有权
标题翻译：兼容低的温度冷却系统
公开(公告)号：EP2632371A1
公开(公告)日：2013-09-04
申请号：EP11835372.1
申请日：2011-09-15
申请人： Medtronic Cryocath LP
发明人： LALONDE, Jean-Pierre
IPC分类号： A61B18/02 , F25B25/02 , F25B40/02
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00577 , A61B2018/0212 , A61B2018/0237 , A61B2018/0262
摘要： A method of operating a medical system, including coupling a medical system to an outlet of a fluid distribution network having a plurality of fluid outlets in a patient treatment center; delivering fluid from the outlet to the medical system; compressing the delivered fluid with the medical system; decreasing the moisture content of the delivered fluid with the medical system; cooling the fluid with the medical system; delivering the fluid from the medical system to a medical device; and removing the fluid from medical device with the medical system.

40. 发明公开

EP2528647A1 MULTIFUNCTIONAL ABLATION DEVICE 无效
标题翻译：多功能消融
公开(公告)号：EP2528647A1
公开(公告)日：2012-12-05
申请号：EP11736557.7
申请日：2011-01-21
申请人： Medtronic Cryocath LP
发明人： PAGEARD, Jean-Luc
IPC分类号： A61M25/01 , A61B18/02 , A61B18/08 , A61M25/098 , A61M25/10
CPC分类号： A61B18/02 , A61B18/1492 , A61B90/39 , A61B2018/00023 , A61B2018/00041 , A61B2018/00214 , A61B2018/0022 , A61B2018/00255 , A61B2018/00285 , A61B2018/00351 , A61B2018/00357 , A61B2018/00375 , A61B2018/00577 , A61B2018/00994 , A61B2018/0212 , A61B2018/0262
摘要： An intravascular catheter is provided, including a flexible elongate body; an expandable element positioned on the elongate body; a substantially linear thermal segment located proximally of the expandable element, the thermal segment defining a first flexibility, where the thermal segment is positioned between two portions of the catheter body each including a flexibility less than that of the thermal segment; a first fluid flow path in fluid communication with the expandable element; and a second fluid flow path in fluid communication with the thermal segment.

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