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21. 发明公开

EP2860528A1 AUTOMATIC ANALYSIS APPARATUS 有权转让
标题翻译：自动分析装置
公开(公告)号：EP2860528A1
公开(公告)日：2015-04-15
申请号：EP13804200.7
申请日：2013-05-24
申请人： Hitachi High-Technologies Corporation
发明人： MAKINO Akihisa , YAMAZAKI Hajime , YOSHIKAWA Keiko , ANDO Manabu , IIJIMA Masahiko
IPC分类号： G01N35/02 , G01N21/82 , G01N33/86
CPC分类号： G01N35/025 , G01N21/11 , G01N21/82 , G01N33/86 , G01N35/00584 , G01N35/00693 , G01N35/0092 , G01N35/1004 , G01N2021/115 , G01N2035/00425 , G01N2035/00673 , G01N2035/0094 , G01N2035/0097 , G01N2035/0437 , G01N2035/0453
摘要： An object of the present invention is to provide a high-throughput automatic analyzer that integrates a biochemical analysis section and a blood coagulation analysis section, the analyzer being capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk having a reaction cell arranged circumferentially thereon, the reaction cell mixing and reacting a sample and a reagent with each other, the reaction disk repeating rotation and stop; a first reagent dispensing mechanism that dispenses a reagent to the reaction cell; a photometer that irradiates a reaction solution in the reaction cell with light to thereby detect light; a reaction cell cleaning mechanism that cleans the reaction cell; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism with a reagent heating function that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to thereby detect transmitted light or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
摘要翻译：本发明的目的在于提供一种将生物化学分析部和血液凝固分析部一体化的高生产率的自动分析装置，能够实现小型化，系统成本以及生命周期成本的降低。该自动分析装置包括：具有沿周向排列的反应单元的反应盘，反应单元使样品和试剂相互混合并反应，反应盘反复旋转并停止; 第一试剂分配机构，其将试剂分配给反应池; 用光照射反应池中的反应溶液从而检测光的光度计; 清洁反应池的反应池清洁机构; 反应容器供应单元，其供应用于使样品和试剂彼此混合和反应的一次性反应容器; 具有试剂加热功能的第二试剂分配机构，其将试剂分配到一次性反应容器; 凝血时间测量部分，其用光照射所述一次性反应容器中的反应溶液，从而检测透射光或散射光; 以及样本分配机构，其将样本分配到反应池和一次性反应容器。

22. 发明公开

EP2804005A1 Apparatus for measuring blood cells and immunity from whole blood 审中-公开
标题翻译：用于测量血细胞和全血免疫的装置
公开(公告)号：EP2804005A1
公开(公告)日：2014-11-19
申请号：EP14168557.8
申请日：2014-05-16
申请人： Horiba, Ltd
发明人： Takemoto, Kazumasa
IPC分类号： G01N35/10 , G01N35/04
CPC分类号： G01N33/491 , G01N33/5304 , G01N35/04 , G01N35/10 , G01N35/1004 , G01N2015/1006 , G01N2035/0437 , G01N2333/46
摘要： A diluted cleaning solution is contacted with the inner wall surface of an immunity measuring cell 19 every time an immunity measurement treatment of a specimen is performed. Therefore, a diluting liquid is injected in advance, then a cleaning solution is injected, whereby a diluted cleaning solution is produced in the immunity measuring cell. As a result, the inner wall surface of the immunity measuring cell is maintained in a preferable state and the interval of the routine cleanings can be prolonged.
摘要翻译：每次进行试样的免疫测量处理时，稀释的清洁溶液与免疫测量单元19的内壁表面接触。因此，预先注入稀释液，然后注入清洁液，由此在免疫测量单元中生成稀释的清洁液。结果，免疫测量单元的内壁表面保持在优选状态，并且可以延长常规清洁的间隔。

23. 发明公开

EP2466315A2 Automated Analyzer 有权转让
标题翻译：自动分析仪
公开(公告)号：EP2466315A2
公开(公告)日：2012-06-20
申请号：EP11194524.2
申请日：2011-12-20
申请人： Jeol Ltd.
发明人： Kondo, Yasushi
IPC分类号： G01N35/02
CPC分类号： G01N35/025 , G01N2035/0437 , G01N2035/1032
摘要： An automated analyzer (100) is offered which can improve its processing capabilities without increasing the size of the instrument or complicating it. The analyzer (100) performs a first processing operation for creating a pretreated specimen by pretreating a specimen with a pretreatment solution in a first reaction cell (2). The analyzer (100) also performs a second processing operation for creating a reacted specimen by reacting the pretreated specimen with a reagent in a second reaction cell (2). The analyzer (100) includes a controller which repeatedly performs a first control operation and a second control operation. In the first control operation, a turntable (4) is rotated through a first angle in a first direction and halted. In the second control operation, the turntable (4) is rotated through a second angle in a second direction and halted. The second reaction cell (2) is spaced by a second angle in a first direction from the first reaction cell (2). Because the first and second control operations are repeated, the turntable (4) is so rotated that the first and second reaction cells (2) are halted at least in first, second, and third positions (P1, P2, P3).
摘要翻译：提供自动分析器（100），其可以在不增加仪器尺寸或使其复杂化的情况下提高其处理能力。分析器（100）通过在第一反应池（2）中用预处理溶液预处理样品来进行用于产生预处理样品的第一处理操作。分析器（100）还通过在第二反应池（2）中使预处理的样品与试剂反应来进行用于产生反应的样品的第二处理操作。分析器（100）包括重复执行第一控制操作和第二控制操作的控制器。在第一控制操作中，转盘（4）沿第一方向旋转第一角度并停止。在第二控制操作中，转盘（4）在第二方向旋转第二角度并停止。第二反应池（2）在第一方向与第一反应池（2）间隔开第二角度。由于第一和第二控制操作被重复，转台（4）被旋转，使得第一和第二反应池（2）至少在第一，第二和第三位置（P1，P2，P3）中停止。

24. 发明公开

EP2405276A1 Labor-Verfahren und Labor-Anordnung zum Speichern und Erstellen von Daten einer entfernten elektrischen Leistungseinrichtung 审中-公开
标题翻译：实验室程序和实验室装置，用于存储和创建远程电力装置的数据
公开(公告)号：EP2405276A1
公开(公告)日：2012-01-11
申请号：EP10007132.3
申请日：2010-07-10
申请人： ABB Technology AG
发明人： Fantana, Nicolaie L. , Kouzine, Oleg , Werle, Peter , Radigk, Cornelia
IPC分类号： G01N35/00 , H01F27/14
CPC分类号： G06F17/30312 , G01N35/00613 , G01N35/00693 , G01N35/00871 , G01N2035/0437
摘要： Es werden ein Labor-Verfahren respektive eine Labor-Anordnung zum Speichern und Erstellen von Daten einer entfernten elektrischen Leistungs-Einrichtung vorgeschlagen,
- wobei Probeentnahme-Behälter (2) zur Aufnahme von Flüssigkeitsproben der entfernten elektrischen Leistungs-Einrichtung verwendet werden,
- wobei "administrative Daten" und eine eindeutige Identifikation der Flüssigkeitsprobe in einem Schreib/Lese-Speicher (3) des Probeentnahme-Behälters (2) abgespeichert sind,
- wobei die Daten des Schreib/Lese-Speichers (3) unter Zuordnung einer vergebenen individuellen Labor-Auftragsnummer von einer Lese/SchreibVorrichtung (4) einer Eingangs-Station (5) des Labors ausgelesen und einer zentralen Labor-Datenbank (10) zugeführt werden,
- wobei die Probeentnahme-Behälter (2) in einem Probeentnahme-Behälter-Lager (8) gelagert werden,
- wobei eine zentrale Diagnose-Vorrichtung (11) zeitlich entkoppelt hiervon eine Diagnose der entnommenen Flüssigkeitsprobe vornimmt und die ermittelten "aktuellen Diagnose-Daten" der zentralen Labor-Datenbank (10) zuführt,
- wobei die zentrale Labor-Datenbank (10) die "aktuellen Diagnose-Daten" und die in der Vergangenheit ermittelten Diagnose-Daten einem individuellen Analysesystem (12) zuführt, welches die Diagnose-Daten miteinander in Beziehung setzt und verarbeitet, um eine Abschätzung betreffend den zukünftigen Betrieb der entfernten elektrischen Leistungs-Einrichtung zu erhalten.
摘要翻译：该方法包括通过一取样容器接收远程电力装置的流体样品（2）没有被安装在取样容器轴承（8）。流体样品的诊断是通过中央诊断装置（11）进行，并且一个中心实验室数据库（10）的实际诊断数据的确定被引导。中心实验室数据库中，提供了实际的诊断数据和诊断数据用于引导到各个分析系统（12）那样设定有关海誓山盟提供一种估计关于在功率器件的手术的诊断数据。因此独立claimsoft包括用于存储和创建远程电力设备的数据，包括取样容器实验室布置。

26. 发明公开

EP2156891A3 System and method for incubating the contents of a reaction receptacle 审中-公开
标题翻译：真菌和系统zur Inkubation des Inhalting einesReaktionsbehälters
公开(公告)号：EP2156891A3
公开(公告)日：2010-06-02
申请号：EP09010368.0
申请日：1999-04-30
申请人： Gen-Probe Incorporated
发明人： Ammann, Kelly G. , Schneider, Robert E. , Smith, Robert J.
IPC分类号： B01L7/00 , G01N35/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A method for incubating the contents of a reaction receptacle at an incubation temperature within a prescribed temperature range, the method comprising the automated steps of:
providing a reaction receptacle to a temperature ramping station constructed and arranged to adjust the temperature of the contents of the reaction receptacle to approximate the incubation temperature and retaining the reaction receptacle within the temperature ramping station for a predetermined length of time; and
moving the reaction receptacle from the temperature ramping station into an incubator that maintains the contents of the reaction receptacle at the incubation temperature and retaining the reaction receptacle within the incubator for a predetermined period of time.
摘要翻译：一种组件，包括：第一环组件，其构造和布置成可围绕第一旋转轴线旋转，所述第一环组件包括环形流体容器承载部分，其具有限定所述流体容器承载部分的内周和外周，所述流体容器承载部分被构造和布置成承载多个流体容器; 以及第二环组件，其构造和布置成可独立于所述第一环组件旋转，围绕大体平行于所述第一旋转轴线的第二旋转轴线旋转，所述第二环组件相对于所述第一环组件定位，使得在所述第二环组件的外周的至少一部分设置在所述第一环组件的所述流体容器承载部分的所述内周边的径向内侧，所述第二环组件被构造和布置成在其上承载多个移液管末端。

27. 发明公开

EP2172777A1 CLEANING DEVICE, METHOD FOR DETECTING CLOGGING OF CLEANING NOZZLE, AND AUTOMATIC ANALYZER 审中-公开
标题翻译：清洁设备，检测方法的阻塞喷嘴和自动分析的
公开(公告)号：EP2172777A1
公开(公告)日：2010-04-07
申请号：EP07767826.6
申请日：2007-06-28
申请人： Beckman Coulter, Inc.
发明人： INAMURA, Shinichi , KAKIZAKI, Kenichi , NEMOTO, Satoshi
IPC分类号： G01N35/02 , G01N35/10
CPC分类号： G01N35/1016 , B01L99/00 , B01L2200/143 , G01N2035/0437 , G01N2035/1018 , Y10T137/0396
摘要： There are provided a cleaning device (20), which has a discharge nozzle (21a) that discharges cleaning liquid, a suction nozzle (21b) that is inserted into a cleaning tank (30) or a reaction vessel (7a) along with the discharge nozzle to suck cleaning liquid or reaction liquid in the cleaning tank or the reaction vessel, and a discard vessel (33) that is connected to the suction nozzle via a pipe (31) to discard the cleaning liquid or the reaction liquid; a method for detecting cleaning nozzle clogging; and an automatic analyzer. The cleaning device (20) includes a detecting unit (36) that detects whether an electrostatic capacity at least between the suction nozzle and an electrode (32) provided in a middle of the pipe exceeds a predetermined threshold value; a determination unit that determines that the suction nozzle is clogged when a time difference between a time, at which the electrostatic capacity exceeds the predetermined threshold value when the suction nozzle is not clogged, and a time, at which the electrostatic capacity exceeds the predetermined threshold value at the time of determination, is not less than a predetermined time difference threshold value; and a control unit (45) that stops the discharge nozzle from discharging the cleaning liquid into the reaction vessel when the determination unit determines that the suction nozzle is clogged.
摘要翻译：本发明提供一种清洁装置（20），它具有一个排放喷嘴（21a）的所做的排放清洗液，吸嘴（21B），其被插入到与排出沿着清洗罐（30）或反应容器（7a）的管嘴吸入清洗中清洗槽或反应容器中，并丢弃容器（33）的液体或反应液那样经由管（31），丢弃该清洗液或者反应液被连接到吸嘴; 用于检测清洁喷嘴堵塞的方法; 和自动分析装置。清洁装置（20）包括在管的中间设置的检测单元（36）没有检测是否对静电容量至少吸嘴（32）之间和在电极超过预定的阈值; 确定单元没有bestimmt，DASS模具吸嘴堵塞时的时间的时间，在该静电电容超过预定阈值。当吸嘴未堵塞之间的时间差，并且，在该静电电容超过预定阈值在判定时的值，不小于预定的时间差阈值以下; 及（45）那样的控制单元从清洗液排出到反应容器中当确定单元bestimmt，DASS模具吸嘴堵塞停止排出喷嘴。

28. 发明公开

EP2082806A2 Automated diagnostic analyzer and method 审中-公开
标题翻译： AutomatischesDiagnoseanalysegerätund Verfahren
公开(公告)号：EP2082806A2
公开(公告)日：2009-07-29
申请号：EP09004018.9
申请日：1999-04-30
申请人： Gen-Probe Incorporated
发明人： Ammann, Kelly , Burns, Ralph, E. , Hansberry, Ernest, V. , Horner, Glenn, A. , Jakub, Cheryl, A. , Kling, John, E. , Nieglos, Donald, J. , Schneider, Robert, E. , Smith, Robert, J.
IPC分类号： B01L7/00 , G01N35/00
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： The present invention relates to an automated analyzer (50) for use in performing a nucleic acid-based assay, the analyzer (50) comprising within a housing (60): a magnet moving structure (810) for subjecting a sample to a magnetic field, wherein the magnet moving structure (810) carries a plurality of magnets (814); an aspirator tube (860) for aspirating a fluid component of the sample while the sample s subjected to the magnetic field of the magnet moving structure (810); an amplification incubator (604) comprising a housing (610) including a receptacle access opening (614) that is sized for moving a reaction receptacle (162) into or out of the amplification incubator (604), wherein the reaction receptacle (162) is suspected of containing a target nucleic acid separated from the fluid component of the sample; and a detection device (950) for detecting a light signal associated with an amplification product formed in the amplification incubator (604), the amplification product being indicative of the presence of the target nucleic acid in the sample.
摘要翻译：本发明涉及用于进行基于核酸的测定的自动分析仪（50），所述分析仪（50）包括在壳体（60）内的磁体移动结构（810），用于使样品经受磁场，其中所述磁体移动结构（810）承载多个磁体（814）; 用于吸收样品的流体组分的吸气管（860），同时受到磁体移动结构（810）的磁场的样品; 扩增培养箱（604），包括壳体（610），壳体（610）包括容纳通道开口（614），其尺寸适于将反应容器（162）移入或移出放大培养箱（604），其中反应容器（162）怀疑含有从样品的流体组分分离的靶核酸; 以及用于检测与在扩增培养箱（604）中形成的扩增产物相关联的光信号的检测装置（950），所述扩增产物指示样品中靶核酸的存在。

29. 发明公开

EP2019321A1 CLEANING EQUIPMENT AND AUTOMATIC ANALYZER 审中-公开
标题翻译： REINIGUNGSEINRICHTUNG UND ANALYSEAUTOMAT
公开(公告)号：EP2019321A1
公开(公告)日：2009-01-28
申请号：EP07741948.9
申请日：2007-04-19
申请人： Olympus Corporation
发明人： KATO, Ko
IPC分类号： G01N35/02 , G01N33/543
CPC分类号： B01L99/00 , B01L3/021 , B01L2200/146 , B01L2400/0487 , G01N2035/00564 , G01N2035/0437 , G01N2035/1025
摘要： Provided is a cleaning apparatus and an automatic analyzer which can accurately detect an abnormality of a liquid-surface position of a reaction liquid contained in a reaction vessel in a B/F cleaning of the reaction liquid undergoing a heterogeneous reaction, and which can easily perform maintenance. To this end, included are a plurality of air nozzles that discharge air from above each of the distal ends of a suction nozzle and a discharge nozzle, the suction nozzle sucking in at least some of reaction liquid undergoing a heterogeneous reaction, the discharge nozzle discharging a predetermined B/F cleaning fluid, the air nozzles being provided corresponding respectively to a plurality of pairs of the suction nozzle and the discharge nozzle; an air supply unit that supplies air to the plurality of air nozzles at a time; a plurality of pressure sensors each of which detects a pressure of air which is supplied by the air supply unit and which is in the vicinity of each proximal end of the air nozzles; and a control unit that individually controls the B/F-cleaning-fluid discharging operation of the discharge nozzles based on the respective pressures detected by the plurality of pressure sensors and changes in the pressures.
摘要翻译：本发明提供一种清洗装置和自动分析装置，能够精确地检测反应容器内所含的反应液的液面位置异常，进行反应液的B / F清洗，能够容易地进行保养。为此，包括多个空气喷嘴，其从吸嘴和排出喷嘴的每个远端上方排出空气，吸嘴吸入至少一些经历多相反应的反应液体，排出喷嘴排出预定的B / F清洗流体，分别对应于多对吸嘴和排出喷嘴设置空气喷嘴; 空气供给单元，一次向多个空气喷嘴供给空气; 多个压力传感器，每个压力传感器检测由空气供应单元供应并且在空气喷嘴的每个近端附近的空气的压力; 以及控制单元，其基于由多个压力传感器检测到的相应压力和压力变化来单独地控制排出喷嘴的B / F清洗流体排出操作。

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