专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明公开

EP0109559A1 High-efficiency yeast vector plasmid and method of its use 失效
标题翻译：质粒载体用于具有高实用性和方法及其使用的酵母。
公开(公告)号：EP0109559A1
公开(公告)日：1984-05-30
申请号：EP83110471.6
申请日：1983-10-20
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Oshima, Takehiro , Tanaka, Shoji , Nakazato, Hiroshi
IPC分类号： C12N15/00
CPC分类号： C12N9/0008 , C07K14/665 , C07K2319/00 , C07K2319/02 , C07K2319/75 , C12N15/81 , C12Y102/01009
摘要： A yeast vector having a gene for the target peptide combined with a promoter for an operon which controls glyceraldehyde-3-phophate dehydrogenase which is one of the enzymes taking part in the glycolysis of a yeast strain, Saccharomyces, a process for preparing the vector and a process for producing the target peptide from yeast in high yield by using such vector.
摘要翻译：具有用于靶肽与操纵子为一个启动子，其控制甘油醛-3-磷酸脱氢酶组合的基因的酵母载体的所有这是参与的酵母菌株的糖酵解的酶中的一种，酿酒，用于制备所述载体的方法和用于通过使用搜索矢量从生产以高收率酵母的靶肽的方法。

22. 发明授权

EP0199446B1 Penem compounds, production and use thereof 有权转让
标题翻译： PENEM化合物，生产和使用
公开(公告)号：EP0199446B1
公开(公告)日：1990-06-13
申请号：EP86301642.4
申请日：1986-03-07
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Ishiguro, Masaji Suntory Inst. Biomedical Research , Iwata, Hiromitsu Suntory Inst. Biomedical Research , Nakatsuka, Takashi Suntory Inst. Biomed. Research
IPC分类号： C07D499/00 , A61K31/43
CPC分类号： C07D499/88 , Y02P20/55

23. 发明公开

EP0147175A3 Novel basic polypeptides and a method of producing thereof 失效
标题翻译：新型基础聚合物及其生产方法
公开(公告)号：EP0147175A3
公开(公告)日：1987-02-25
申请号：EP84308923
申请日：1984-12-19
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Okada, Tsutomu , Tanaka, Shoji , Oshima, Takehiro , Yamamoto, Kazumori
IPC分类号： C12P21/02 , C12N15/00 , C07K15/26 , A61K45/02
CPC分类号： C07K14/57 , A61K38/00
摘要： A novel basic polypeptide having an immune interferon-like activity consists of 131 or 132 amino acid residues and has an apparent molecular weight of about 16,000 as measured by SDS electrophresis and of about 17,000 as measured by the high performance liquid chromatographic molecular sieve method; an isoelectric point (PI value) in the nge of 9.2-10.0; a cystein or methionine residue as the amino terminal; a lysine residue as the carboxy terminal; and the amino acid composition: Asx 20, Thr 5, Ser 9, Glx 16, Pro 2, Gly 4, Ala 7, Cys 2, Val 8, Met 3 or 4, Ile 7, Leu 9, Tyr 5, Phe 9, Lys 19, His 2, Arg 3 and Trp 1 (Asx including Asp and Asn, and Glx including Glu and Gin). The polypeptide is produced by cultivating a microorganism such as Escher ichia coli transformed with a plasmid containing a chemically synthesized DNA sequence coding for the corresponding amino acid sequence and extracting the polypeptide from the culture.
摘要翻译：具有免疫干扰素样活性的新型碱基多肽由131或132个氨基酸残基组成，并且通过SDS电泳法测量的表观分子量为约16,000，通过高效液相色谱分子筛法测量为约17,000; 等电点（PI值）在9.2-10.0的范围内; 作为氨基末端的半胱氨酸或甲硫氨酸残基; 赖氨酸残基作为羧基末端; 氨基酸组成：Asx 20，Thr 5，Ser 9，Glx 16，Pro 2，Gly 4，Ala 7，Cys 2，Val 8，Met 3或4，Ile 7，Leu 9，Tyr 5，Phe 9， Lys 19，His 2，Arg 3和Trp 1（Asx包括Asp和Asn，Glx包括Glu和Gln）。通过培养用包含编码相应氨基酸序列的化学合成的DNA序列的质粒转化的微生物，从培养物中提取多肽来产生多肽。

24. 发明公开

EP0171912A1 Pyrrolizidine compounds, methods for their production, and their uses 有权
标题翻译： Pyrrolizidinverbindungen，其制备方法和应用方法。
公开(公告)号：EP0171912A1
公开(公告)日：1986-02-19
申请号：EP85304823.9
申请日：1985-07-05
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Miyano, Seiji , Sumoto, Kunihiro , Satoh, Fumio
IPC分类号： C07D487/04 , A61K31/40
CPC分类号： C07D487/04
摘要： A novel pyrrolizidine compound of the formula
(wherein R 1 is an alkyl group of 1 to 4 carbon atoms or a phenyl group; and R 2 and R 3 are such that at least one of them is an alkyl group of 1 to 4 carbon atoms with the other, if any, being a hydrogen atom) is produced by reacting Δ 4(8) -dehydropyrrolizidine with a substituted malonic acid and thus formed 2-substituted-8-pyrrolizidineacetic acid with a substituted aniline. The product is optionally subjected to optical resolution. The pyrrolizidine compound has more potent antiarrhythmic activity than known similar pyrrolizidine compounds.

25. 发明公开

EP0109560A3 Yeast plasmid vector capable of induced expressing and method of using said plasmid 失效
标题翻译：诱导表达的YEAST PLASMID矢量和使用合适的PLASMID的方法
公开(公告)号：EP0109560A3
公开(公告)日：1985-11-27
申请号：EP83110472
申请日：1983-10-20
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Oshima, Takehiro , Arima, Kenji , Tanaka, Shoji , Nakazato, Hiroshi
IPC分类号： C12N15/00 , C12P21/02
CPC分类号： C07K14/665 , C07K2319/00 , C07K2319/75 , C12N9/14 , C12N9/16 , C12N15/65 , C12N15/81
摘要： A yeast vector for producing a useful peptide under the control of the promoter of PH05 gene which is a gene controlling a repressible yeast acid phosphatase, a process of preparing the same and a process for producing the useful peptide in high yield by culturing the yeast that has been transformed by said vector are disclosed.

26. 发明公开

EP0134673A1 Improved plasmid vector and use thereof 有权
标题翻译： Plasmidvektor和seine Verwendung。
公开(公告)号：EP0134673A1
公开(公告)日：1985-03-20
申请号：EP84304901.6
申请日：1984-07-18
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Ohsuye, Kazuhiro , Tanaka, Shoji
IPC分类号： C12N15/70
CPC分类号： C12N15/70 , C07K14/57
摘要： Escherichia coli plasmid vectors characterized in that they have a 5'-terminal untranslated region (inclusive of the propoter region and Shine-Dargano sequence) of the Escherichia .coli lipoprotein gene, which region is improved to thereby enable direct production of useful polypeptides in substantially complete form.
摘要翻译：大肠杆菌质粒载体的特征在于它们具有大肠杆菌脂蛋白基因的5分钟末端非翻译区（包括推进物区和Shine-Dargano序列），该区被改进，从而能够直接产生基本上完整的有用多肽形成。

27. 发明公开

EP0162208A3 Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions 有权
标题翻译：新型N-取代的3,4-二羟基嘧啶衍生物，其制备方法和药物组合物
公开(公告)号：EP0162208A3
公开(公告)日：1986-11-26
申请号：EP85102645
申请日：1985-03-08
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Cho, Hidetsura , Aisaka, Kazuo , Satoh, Fumio , Ishihara, Takafumi
IPC分类号： C07D239/20 , A61K31/505
CPC分类号： C07D239/20
摘要： N-substituted 3,4-dihydropyrimidine derivatives of the formula:
wherein X'. X 2 , X 3 and R', R 2 have the meanings shown in the claims, and pharmaceutically acceptable acid addition salts thereof. In form of pharmaceutical compositions they are useful as agents for treating disorders of the cardiovascular system, for example, as hypotensive agents, agents for ameriolation of brain circulation and anti-angina pectoris agents. Processes for producing the above compounds economically and effectively are also disclosed.

28. 发明公开

EP0095351A2 A precursor of a C-terminal amidated peptide and production thereof 有权
标题翻译： Vorläufereines an dem C-Ende amidierten Peptids und dessen Herstellung。
公开(公告)号：EP0095351A2
公开(公告)日：1983-11-30
申请号：EP83302916.8
申请日：1983-05-20
申请人： SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD.
发明人： Tanaka, Shoji , Ohsuye, Kazuhiro , Kubota, Ichiro , Ohnuma, Norio , Noguchi, Teruhisa
IPC分类号： C12N15/00 , C07K7/36 , C07H21/04 , C12P21/02 , C12N1/00 , C12N5/00
CPC分类号： C07K14/585 , A61K38/00
摘要： A precursor of a C-terminal amidated peptide represented by the general formula P-X-Gly-Y n , wherein P is a peptide residue, X is an amino acid residue the C terminal of which (on the Gly side) can be converted in vivo to a -CONH 2 group, Gly is a glycine residue, Y is a basic amino acid residue, n is an interger of 2 to 4 and a further amino acid residue other than Y or a peptide residue may be attached to Y n , is produced by a gene engineering technology. The precursor exhibits in vivo physiological activity like the C-terminal amidated peptide.
摘要翻译：由通式PX-Gly-Yn表示的C末端酰胺化肽的前体，其中P是肽残基，X是其C末端（Gly侧）可以在体内转化的氨基酸残基， -CONH 2基，Gly是甘氨酸残基，Y是碱性氨基酸残基，n是2至4的整数，除Y之外的另外的氨基酸残基或肽残基可以连接到Yn上，由基因工程技术。前体表现出体内生理活性，如C-末端酰胺化肽。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式