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11. 发明公开

EP2172470A4 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX 审中-公开
标题翻译：联吡啶，过渡金属络合物和方法用于生产芳香族共轭体系连接使用过渡金属配合物
公开(公告)号：EP2172470A4
公开(公告)日：2011-08-31
申请号：EP08765824
申请日：2008-06-18
申请人： SUMITOMO CHEMICAL CO
发明人： ASAUMI TAKU , KAMIKAWA TAKASHI
IPC分类号： C07F7/10 , C07C15/14 , C07C39/15 , C07C43/164 , C07C43/205 , C07C49/784 , C07D239/28 , C07D333/02 , C07F7/12 , C07F15/04 , C08F4/70
CPC分类号： C07C39/15 , C07C1/26 , C07C45/72 , C07C49/84 , C07C2523/06 , C07C2531/22 , C07D239/28 , C07D333/02 , C07F7/0812 , C07F7/0814 , C07C15/14 , C07C49/784

12. 发明授权

EP2125201B1 VERFAHREN ZUR SELEKTIVEN METHANISIERUNG VON KOHLENMONOXID 有权
标题翻译：过程中选择性甲烷化一氧化碳
公开(公告)号：EP2125201B1
公开(公告)日：2011-04-13
申请号：EP08716869.6
申请日：2008-02-15
申请人： BASF SE
发明人： STEINER, Jochen , HÖLZLE, Markus , URTEL, Heiko
IPC分类号： B01J23/46 , C07C1/04 , C07C1/12 , H01M8/06
CPC分类号： B01J23/63 , B01J23/002 , B01J23/462 , B01J37/0009 , C01B3/586 , C01B2203/0205 , C01B2203/0283 , C01B2203/0445 , C01B2203/047 , C01B2203/066 , C07C1/0435 , C07C1/26 , C07C17/10 , C07C2529/40 , H01M8/0668 , C07C9/00 , C07C19/075
摘要： The invention relates to a catalytic composition and to a method for the selective methanation of carbon monoxide in hydrogen and carbon dioxide-containing flows, wherein ruthenium is used as the active component and a lanthanum-cerium-zirconium oxide is used as the carrier material. The invention further relates to their use in fuel cell systems.

13. 发明公开

EP2121569A2 NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS 审中-公开
标题翻译： AS离子通道调节合适的新ZIMTSÄUREAMIDDERIVATE
公开(公告)号：EP2121569A2
公开(公告)日：2009-11-25
申请号：EP07857649.3
申请日：2007-12-17
申请人： NeuroSearch A/S
发明人： NARDI, Antonio , GRUNNET, Morten , DEMNITZ, Joachim , JENSEN, Thomas, Diness , CHRISTOPHERSEN, Palle , JONES, David, Spencer , NIELSEN, Elsebet, Østergaard , STRØBÆK, Dorte , MADSEN, Lars, Siim
IPC分类号： C07C205/56 , C07C233/29 , C07C233/44 , C07C233/55 , C07C261/04 , C07C309/51 , C07C309/76 , C07C311/16 , C07C311/46 , C07C311/51 , A61K31/00 , A61P15/00
CPC分类号： C07C309/15 , C07C1/26 , C07C17/10 , C07C311/08 , C07C311/09 , C07C311/21 , C07C311/46 , C07C311/51 , C07C2529/40 , C07C9/00 , C07C19/075
摘要： This invention relates to novel cinnamic amide derivatives that are found to be potent modulators of ion channels and, as such, they are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to modulation of ion channels.

14. 发明公开

EP2069289A1 ISOSERINDERIVATE ALS INHIBITOREN DES KOAGULATIONSFAKTORS IXA 有权
标题翻译：凝血因子IXA的ISOSERINDERIVATE ALS抑制剂
公开(公告)号：EP2069289A1
公开(公告)日：2009-06-17
申请号：EP07802031.0
申请日：2007-08-31
申请人： Sanofi-Aventis
发明人： STEINHAGEN, Henning , FOLLMANN, Markus , GOERLITZER, Jochen , SCHREUDER, Herman
IPC分类号： C07C237/22 , C07D207/34 , C07D209/42 , C07D213/56 , C07D215/48 , C07D217/22 , C07D235/30 , C07D239/28 , C07D239/95 , C07D241/44 , C07D277/82 , C07D307/54 , C07D307/85 , C07D333/38
CPC分类号： C07D277/82 , C07C1/26 , C07C17/10 , C07C2529/40 , C07D207/34 , C07D209/42 , C07D213/56 , C07D215/48 , C07D217/22 , C07D235/30 , C07D239/28 , C07D239/95 , C07D241/44 , C07D307/54 , C07D307/85 , C07D333/38 , C07D333/70 , C07D405/12 , C07C9/00 , C07C19/075
摘要： The invention relates to the compounds of formula (I) having antithrombotic activity which especially inhibit blood coagulation factor IXa, to methods for producing the same and to the use thereof as drugs.

15. 发明公开

EP1975154A1 Process for Producing Methionine 有权
标题翻译： HerstellungsverfahrenfürMethionin
公开(公告)号：EP1975154A1
公开(公告)日：2008-10-01
申请号：EP08153073.5
申请日：2008-03-20
申请人： Sumitomo Chemical Company, Limited
发明人： Fujita, Kazuo , Onishi, Kozo
IPC分类号： C07C319/20 , C07C323/58
CPC分类号： C07C1/26 , C07C17/10 , C07C2529/40 , C07C9/00 , C07C19/075
摘要： A process for producing methionine by hydrolysis of 5-(β-methylmercaptoethyl)hydantoin in the presence of an alkali, in which the concentration of hydrogen sulfide is 5 ppm or less in a solution used for hydrolysis comprising 5-(β-methylmercaptoethyl)hydantoin and the alkali, whereby methionine can be stably produced for a long period of time.
摘要翻译：在含有5-（2-甲基巯基乙基）乙内酰脲的水解溶液中硫酸盐浓度为5ppm以下的碱存在下，通过5-（2-甲基巯基乙基）乙内酰脲的水解生产甲硫氨酸的方法和碱，由此可以长时间稳定地生产甲硫氨酸。

16. 发明公开

EP1868967A1 HYDROCARBON SYNTHESIS 有权
标题翻译：烃合成
公开(公告)号：EP1868967A1
公开(公告)日：2007-12-26
申请号：EP06739568.1
申请日：2006-03-24
申请人： GRT, Inc.
发明人： LORKOVIC, Ivan, M.
IPC分类号： C07C1/26 , C10G27/00
CPC分类号： C10G50/00 , C07C1/26 , C07C2521/10 , C07C2523/02 , C07C2529/18 , C07C2529/40 , C10G27/00 , C10G2400/02 , C10G2400/20 , C10G2400/22 , C10G2400/30 , Y10S585/935 , Y10S585/943
摘要： A method of synthesizing hydrocarbons from smaller hydrocarbons includes the steps of hydrocarbon halogenation, simultaneous oligomerization and hydrogen halide neutralization, and product recovery, with a metal-oxygen cataloreactant used to facilitate carbon-carbon coupling. Treatment with air or oxygen liberates halogen and regenerates the cataloreactant.

18. 发明授权

EP1097158B1 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES 有权
标题翻译：配体的金属和金属催化的过程
公开(公告)号：EP1097158B1
公开(公告)日：2006-01-25
申请号：EP99933785.0
申请日：1999-07-09
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人： BUCHWALD, Stephen , OLD, David, W. , WOLFE, John, P. , PALUCKI, Michael , KAMIKAWA, Ken , CHIEFFI, Andrew , SADIGHI, Joseph, P. , SINGER, Robert, A. , AHMAN, Jens
IPC分类号： C07F7/18 , C07F9/48 , C07F9/50 , C07F9/572 , C07F9/653 , C07F9/6547 , C07F9/6571 , C07F15/00
CPC分类号： C07C17/263 , C07B37/04 , C07C1/26 , C07C29/32 , C07C41/16 , C07C41/30 , C07C45/68 , C07C45/71 , C07C67/31 , C07C67/343 , C07C201/12 , C07C209/10 , C07C209/18 , C07C211/59 , C07C213/02 , C07C213/08 , C07C221/00 , C07C225/12 , C07C227/08 , C07C227/18 , C07C231/12 , C07C249/02 , C07C249/16 , C07C251/24 , C07C253/30 , C07C2601/02 , C07C2601/08 , C07C2601/16 , C07C2602/08 , C07C2602/10 , C07D209/08 , C07D213/50 , C07D213/72 , C07D213/74 , C07D295/023 , C07D295/033 , C07D295/096 , C07D295/112 , C07D295/13 , C07D295/155 , C07D307/33 , C07D317/22 , C07D317/26 , C07D317/66 , C07D333/08 , C07D333/66 , C07D401/04 , C07F7/1892 , C07F9/4875 , C07F9/5022 , C07F9/5027 , C07F9/5728 , C07F9/653 , C07F9/6547 , C07F9/65719 , C07F15/0066 , C07C25/18 , C07C33/24 , C07C49/67 , C07C49/215 , C07C49/782 , C07C49/755 , C07C49/683 , C07C49/657 , C07C49/245 , C07C49/84 , C07C47/575 , C07C49/213 , C07C49/255 , C07C69/92 , C07C69/612 , C07C69/76 , C07C211/48 , C07C211/55 , C07C217/40 , C07C217/84 , C07C217/92 , C07C225/22 , C07C229/36 , C07C229/60 , C07C233/07 , C07C235/46 , C07C251/86 , C07C255/33 , C07C255/50 , C07C255/54 , C07C255/56 , C07C255/58 , C07C205/04 , C07C205/06 , C07C43/205 , C07C43/225 , C07C43/263 , C07C43/29 , C07C43/275
摘要： One aspect of the present invention relates to novel ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject processes provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.

19. 发明授权

EP1307413B1 VERFAHREN ZUR HERSTELLUNG VON OLEFINSUBSTITUIERTEN AROMATEN ODER HETEROAROMATEN 有权
公开(公告)号：EP1307413B1
公开(公告)日：2005-04-27
申请号：EP01967245.0
申请日：2001-08-01
申请人： Covion Organic Semiconductors GmbH
发明人： SPREITZER, Hubert , STÖSSEL, Philipp , BECKER, Heinrich
IPC分类号： C07B37/04 , C07C13/72 , C07C33/28
CPC分类号： C07C29/44 , C07B37/04 , C07C1/26 , C07C2603/18 , C07C2603/94 , C07C13/72 , C07C33/28
摘要： Both low-molecular and high-molecular aromatic or heteroaromatic compounds, which are substituted with olefins, play an important role in industry, for example as auxiliary agents or additives in cosmetic preparations such as sunscreen agents, in diverse fine chemicals and chemicals for the electronics industry and in intermediate products for the pharmaceutical and agrochemical industries. Such compounds are of outstanding importance particularly in the rapid-growth field of organic semiconductors, (e.g. for use in organic or polymer LEDs, organic solar cells and organic integrated circuits). The invention relates to a method for producing olefin-substituted aromatic or heteroaromatic compounds of this type, by reacting a functional aryl or heteroaryl compound with an olefin derivative, which has at least one H-atom on its double bond, in the presence of a simple palladium compound, optionally in the presence of an additive containing nitrogen and of a base in a solvent, to form a C-C-linkage and a formal splitting-off of the aryl, or heteroaryl derivative functional group and of one H-atom of the olefin compound. The invention is characterised by the presence of at least one additive containing metal, which is different from palladium.
摘要翻译：由烯烃取代的低分子量和高分子量芳族和杂芳族化合物在工业中起重要作用，例如作为化妆品制剂中的助剂和添加剂，例如防晒剂，各种精细和电子化学品以及用于药物和农用化学品。此外，特别是在快速增长的有机半导体领域（例如在有机或聚合物发光二极管，有机太阳能电池，有机IC中的应用）中，精确地这些化合物具有突出的意义。本发明涉及通过使官能的芳基或杂芳基化合物与在双键上具有至少一个氢原子的烯烃衍生物在简单的钯化合物存在下反应来制备这种烯烃取代的芳族化合物或杂芳族化合物的方法，任选地在溶剂中存在氮添加剂和碱，形成CC键并正式裂开芳基或杂芳基衍生物的官能团和烯烃化合物的氢原子，其特征在于存在至少一种除钯以外的金属添加剂。

20. 发明公开

EP1377693A2 MICRO-ENGINEERED REACTORS 审中-公开
标题翻译： MIKROREAKTOREN
公开(公告)号：EP1377693A2
公开(公告)日：2004-01-07
申请号：EP02718329.2
申请日：2002-04-05
申请人： AstraZeneca AB
发明人： SHAW, John, Edward, Andrew , SHUTE, Richard, E.
IPC分类号： C25B9/00 , C25B3/00 , C25B3/12 , B01J19/00
CPC分类号： C25B3/12 , B01J19/0093 , B01J2219/00835 , B01J2219/00853 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00936 , B01J2219/00995 , C07C1/26 , C07F1/00 , C07F1/04 , C07F3/02 , C07F7/2212 , C07F9/5352 , C25B3/00 , C07C15/04
摘要： The invention relates to a micro-engineered reactor device comprising a closely coupled reactor and electrochemical cell, and a method of using such a reactor for the synthesis of organic compounds by a process involving an electrochemical reaction. The synthetic processes are of a type in which a source material is electrochemically converted to a reactive primary product which is exposed at a reaction region within a channel, or chamber, to a precursor material so that the primary product and precursor material react to generate a secondary product.

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