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131. 发明公开

EP1160612A1 Transportvorrichtung für Objektträger 审中-公开
标题翻译： TransportvorrichtungfürObjektträger
公开(公告)号：EP1160612A1
公开(公告)日：2001-12-05
申请号：EP00810466.3
申请日：2000-05-29
申请人： Sulzer Medica AG
发明人： Frei, Heribert , Hildebrand, Steven , Brunner, Andreas , Tommasini, Roberto , Müller, Werner, Dr.
IPC分类号： G02B21/34 , B01L3/00
CPC分类号： B01L3/508 , B01L2200/027 , B01L2300/0822 , G01N1/2813 , G02B21/34
摘要： Die Erfindung zeigt eine Transportvorrichtung für Objektträger (1), an denen Präparate (2) in einer Trägerflüssigkeit (3) auf einer vorgegebenen, ebenen Fläche (5) anlagerbar sind. Ein Gegenkörper (6) steht innerhalb einer Dichtung (4) bis knapp an die ebene Fläche (5) vor, um ein nur kleines Volumen (7) einzuschliessen. Der Gegenkörper besitzt mindestens eine Aussparung (8) innerhalb dieses kleinen Volumens (7) und ein der Aussparung vorgelagertes Dichtelement (9) zur Atmosphäre, welches ohne seine Dichtwirkung zu verlieren mit einer Kanüle (10) wiederholt durchstechbar ist.
摘要翻译：输送装置具有封闭平面（5）的密封件（4）。以及将密封件压靠在显微镜载玻片（1）上以包围容积（7）的对置体（6）。该密封体在密封件内突出到平坦的表面，以仅包围一小部分体积。对置体在体积内具有至少一个凹部（8）和密封元件（9），该密封元件（9）在不影响密封的情况下用空心针（10）刺穿。优选特征：用于一针的密封元件由由圆形材料组成的弹性密封件（4）形成。相对体位于密封件内，形成与平面的间隙（S）为0.01-1mm。计数器主体连接到通过其后侧（13）支撑滑块的框架（12）。

132. 发明公开

EP1102102A2 Adhesive label with grid for microscope slide 有权
标题翻译： Klebeetikett mit GitterfürMikroskopobjektträger
公开(公告)号：EP1102102A2
公开(公告)日：2001-05-23
申请号：EP00310364.5
申请日：2000-11-22
申请人： Genpak Limited
发明人： Burke, Julian , Patel, Nishith
IPC分类号： G02B21/34 , G01N1/28
CPC分类号： G09F3/10 , B01J2219/00527 , B01J2219/00529 , B01J2219/00533 , B01J2219/0054 , B01J2219/00542 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00659 , C40B70/00 , G02B21/34
摘要： An adhesive label 3 for attaching to a microscope slide 1 is disclosed. The label 3 may have one or more grids or arrays 2 provided on it to help an operator to manually spot a microscope slide 1.
摘要翻译：公开了一种用于附接到显微镜载玻片1的粘合标签3。标签3可以具有设置在其上的一个或多个网格或阵列2，以帮助操作者手动地点击显微镜幻灯片1.

133. 发明授权

EP0896238B1 Stereomikroskop mit einem Probenwechsler 失效
标题翻译：体视显微镜用样品转换
公开(公告)号：EP0896238B1
公开(公告)日：2001-02-21
申请号：EP98113754.0
申请日：1998-07-23
申请人： Carl Zeiss Jena GmbH
发明人： Kraft, Winfried, Dipl.-Ing. , Schwab, Klaus Dieter
IPC分类号： G02B21/22 , G02B21/26 , G02B21/34
CPC分类号： G02B21/22 , G02B21/26

134. 发明公开

EP0974044A1 LASER CAPTURE MICRODISSECTION ANALYSIS VESSEL 失效
标题翻译：激光捕获显微分析船
公开(公告)号：EP0974044A1
公开(公告)日：2000-01-26
申请号：EP98903663.7
申请日：1998-01-22
申请人： Arcturus Engineering, Inc.
发明人： BAER, Thomas, M. , HEAD, David, F.
IPC分类号： G01N1/28 , G02B21/34
CPC分类号： B01L3/50853 , B01L3/50825 , B01L2300/021 , B01L2300/047 , G01N1/2813 , G01N2001/284 , G02B21/34
摘要： A laser capture microdissection lift-off substrate comprising a transparent thermoplastic film is incorporated into substrate which may take the form of a cap or other structure associated with an analysis vessel or which may be used with a holder or other element of a LCM tissue sample transfer apparatus. The thermoplastic lift-off substrate film is held in a fixed position on the substrate which may be relative to a feature of a biological analysis vessel. The film may be affixed to a substrate which is a structure which goes into the vessel such that the sample is held in a fixed position relative to an observation port on the vessel.
摘要翻译：包括透明热塑性薄膜的激光捕获显微切割剥离基底被结合到衬底中，衬底可以采取与分析容器相关联的帽或其他结构的形式或者可以与保持器或LCM组织样本转移的保持器或其他元件一起使用仪器。热塑性剥离基材薄膜保持在可能相对于生物分析容器的特征的基材上的固定位置。膜可以被固定到基板上，该基板是进入容器的结构，使得样品相对于容器上的观察端口保持在固定位置。

135. 发明公开

EP0896238A3 Stereomikroskop mit einem Probenwechsler 失效
标题翻译： Probenwechsler Stereomikroskop mit einem Probenwechsler
公开(公告)号：EP0896238A3
公开(公告)日：1999-12-15
申请号：EP98113754.0
申请日：1998-07-23
申请人： Carl Zeiss Jena GmbH
发明人： Kraft, Winfried, Dipl.-Ing. , Schwab, Klaus Dieter
IPC分类号： G02B21/22 , G02B21/26 , G02B21/34
CPC分类号： G02B21/22 , G02B21/26
摘要： Stereomikroskop mit einem Probenwechsler , der zumindest teilweise um eine Stativsäule drehbar ausgebildet ist und auf einer durch den Beobachtungsstrahlengang gehenden Kreisbahn angeordnete Probenaufnahmen aufweist, wobei vorteilhaft der Probenwechsler aus einem inneren unbeweglichen Teil und einem ringförmigem äußeren Teil besteht , der die Probenaufnahmen beinhaltet und die
Probenaufnahmen einen Durchmesser aufweisen , der zur Aufnahme handelsüblicher Petrischalen geeignet ist.
摘要翻译：样品更换器（8）至少部分地围绕支柱（3）旋转。它装配有样品架（17），定位成使得当样品更换器旋转时，它们通过显微镜（1）的视场。样品转换器由内部固定部分（9）和环形外部部分（10）组成，其中包含试样支架。支架具有适于接受市售培养皿的直径。

136. 发明授权

EP0768520B1 A reusable slide assembly for use in analysis with a microscope 失效
标题翻译：在显微镜检查使用可重复的滑动组件
公开(公告)号：EP0768520B1
公开(公告)日：1999-04-21
申请号：EP96203251.2
申请日：1993-05-18
申请人： DIASYS CORPORATION
发明人： Greenfield, Walter , Kemble, James E. , Kearnes, Edward G.
IPC分类号： G01N21/03 , G02B21/34
CPC分类号： B01L3/502 , B01L3/5082 , B01L2300/0822 , B01L2300/0877 , G01N21/05 , G01N33/493 , G01N35/1004 , G01N35/1095 , G02B21/34

137. 发明公开

EP0813086A3 Method and apparatus for analyzing blood samples 失效
标题翻译：对于血液样品的分析方法和装置
公开(公告)号：EP0813086A3
公开(公告)日：1999-01-27
申请号：EP97108539.4
申请日：1997-05-27
申请人： Levine, Robert Aaron , Wardlaw, Stephen Clark
发明人： Levine, Robert Aaron , Wardlaw, Stephen Clark
IPC分类号： G02B21/34
CPC分类号： B01L3/5021 , G01N33/491 , G01N2015/055 , G02B21/34 , Y10S435/81 , Y10S435/97 , Y10S436/805 , Y10S436/81
摘要： Centrifuged anticoagulated blood samples are analyzed under magnification in a centrifuge tube containing a layer-elongating insert, which tube is placed on a calibrated slide. The slide includes a slot in which the tube is placed. A calibrated scale is disposed adjacent to the slot for use in measuring various blood sample parameters, such as hematocrit, platelet count, and the like. Anemia and/or low platelet counts are indicative of potentially serious complications of malaria. Their detection will prompt a physician to consider the liklihood of serious illness due to malaria. The presence or absence of blood-borne parasites can also be determined using the procedures of this invention. Thus the device allows a blood sample to be analyzed for malaria parasites, and also allows measurement of hematicrit and platelet counts. The scale can be presented in a normal image when a simple lens magnification, such as a magnifying glass, is used to view the tube and slide; and can also be presented in mirror image when compound lens magnification, such as a microscope, is used to view the tube and slide.

138. 发明公开

EP0801732A4 METHOD AND APPARATUS FOR TREATMENT OF HUMAN OR ANIMAL CELL SAMPLES 失效
标题翻译：方法和一种用于治疗人体或动物细胞样本
公开(公告)号：EP0801732A4
公开(公告)日：1999-01-07
申请号：EP96900204
申请日：1996-01-04
申请人： AUSTRALIAN BIOMEDICAL
发明人： PALANDER JARI
IPC分类号： G01N33/48 , B01F11/00 , C12M3/00 , G01N1/28 , G01N1/30 , G01N1/31 , G02B21/34
CPC分类号： G01N1/312 , B01F11/0042 , G01N1/2813 , G02B21/34 , Y10T436/112499 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： Apparatus for treatment of human or animal cell samples (4) on a microscopic slide (2) includes an element (1) having a recessed face (6) defined by rails (7) which are adapted to slide on surface (3) of the slide (2). An opening (13) at the leading edge of the element (1) has a bevelled edge (5) and provides access to a cavity (6) formed between the face and the surface (3) of the slide (2) when the rails (7) bear on the slide (2). The slide (2) is tilted slightly and a vacuum nozzle (8) is arranged at the lower edge of the slide (2). An end stop (9) may be clamped to the end of the slide (2) opposite to the end where the nozzle (8) is located and has a bevelled edge complimentary to the bevelled edge (5) of the element (1) for closing the opening (13). A method of spreading liquid over the surface (3) and the sample (4) involves placing the rails (7) on the surface (3) with the cavity (6) displaced laterally from the sample (4) and the face (6) and surface (3) parallel, dispensing the liquid onto the surface (3) and moving the element (1) relative to the surface (3) whereby the liquid becomes trapped in the cavity (6), and is spread evenly over the sample (4). The method also involves removing excess liquid after incubation by exposing the cavity (6) to the vacuum nozzle by sliding the element (1) over the lower edge of the slide (2) and allowing the nozzle to suck the excess liquid away. Further treatment liquid may be added adjacent to the opening during the suction process to provide a second treatment without exposing the sample (4) to air between treatments.

139. 发明公开

EP0884394A3 Apparatus for assembly of an in situ PCR sample and reagent fluid containment system on a glass slide 失效
标题翻译：用于在载玻片上组装原位PCR样品和试剂流体容纳系统的装置
公开(公告)号：EP0884394A3
公开(公告)日：1998-12-23
申请号：EP98115093.1
申请日：1993-09-30
申请人： The Perkin Elmer Corporation
发明人： Atwood, John G. , Haff, Larry
IPC分类号： C12Q1/68 , G02B21/34 , B01L7/00
CPC分类号： G01N1/312 , B01J19/0046 , B01J2219/00722 , B01L3/508 , B01L7/52 , B01L9/52 , B01L2200/0684 , B01L2200/0689 , B01L2300/041 , B01L2300/0822 , B01L2300/1827 , B01L2300/185 , C12Q1/6841 , C12Q1/686 , C40B40/06 , Y10S435/809 , C12Q2543/101
摘要： An apparatus (80) for assembly of an in situ PCR sample and reagent fluid containment system on a glass slide (14), wherein said containment system comprises a cover member (16) and a retaining assembly (20,22, 28), said apparatus comprising: a base (45); a support platform (42) mounted on said base, said support platform having a generally horizontal top surface for receiving and supporting components of said retaining assembly and said slide in a predetermined spaced relation; an elongate compression arm (84) movably supported from said base at a position spaced from said platform, said arm being operative to compress said glass slide and said retaining assembly together in close contact; and a retaining assembly installation mechanism (86) positioned so as to install said retaining assembly onto said slide (14) while said compression arm (84) is compressing said glass slide (14) and said retaining assembly together.
摘要翻译：一种用于在玻璃载玻片（14）上组装原位PCR样品和试剂流体容纳系统的设备（80），其中所述容纳系统包括盖构件（16）和保持组件（20,22,28），所述设备，包括：基座（45）; 安装在所述基座上的支撑平台（42），所述支撑平台具有大致水平的顶表面，用于以预定的间隔关系接收和支撑所述保持组件和所述滑块的部件; 在与所述平台间隔开的位置处从所述基部可移动地支撑的细长压缩臂（84），所述臂可操作以将所述载玻片和所述保持组件紧密接触地压缩在一起; 和保持组件安装机构（86），当所述压缩臂（84）将所述玻璃滑块（14）和所述保持组件压缩在一起时，所述保持组件安装机构（86）定位成将所述保持组件安装到所述滑块（14）上。

140. 发明公开

EP0884394A2 Apparatus for assembly of an in situ PCR sample and reagent fluid containment system on a glass slide 失效
标题翻译：装置用于在薄片原位PCR构建一个样品和试剂接收系统，用于
公开(公告)号：EP0884394A2
公开(公告)日：1998-12-16
申请号：EP98115093.1
申请日：1993-09-30
申请人： The Perkin Elmer Corporation
发明人： Atwood, John G. , Haff, Larry
IPC分类号： C12Q1/68 , G02B21/34 , B01L7/00
CPC分类号： G01N1/312 , B01J19/0046 , B01J2219/00722 , B01L3/508 , B01L7/52 , B01L9/52 , B01L2200/0684 , B01L2200/0689 , B01L2300/041 , B01L2300/0822 , B01L2300/1827 , B01L2300/185 , C12Q1/6841 , C12Q1/686 , C40B40/06 , Y10S435/809 , C12Q2543/101
摘要： An apparatus (80) for assembly of an in situ PCR sample and reagent fluid containment system on a glass slide (14), wherein said containment system comprises a cover member (16) and a retaining assembly (20,22, 28), said apparatus comprising: a base (45); a support platform (42) mounted on said base, said support platform having a generally horizontal top surface for receiving and supporting components of said retaining assembly and said slide in a predetermined spaced relation; an elongate compression arm (84) movably supported from said base at a position spaced from said platform, said arm being operative to compress said glass slide and said retaining assembly together in close contact; and a retaining assembly installation mechanism (86) positioned so as to install said retaining assembly onto said slide (14) while said compression arm (84) is compressing said glass slide (14) and said retaining assembly together.
摘要翻译：在载玻片上的装置（80），用于的组件原位PCR的样品和试剂的流体容纳系统（14）worin所述容纳系统包括盖构件（16）和一个保持组件（20,22，28），所述装置，包括：一个基座（45）; 支撑平台（42）安装在基座说，所说的基因的反弹水平顶面支撑平台，用于接收和在预定的间隔关系支撑所述保持组件和所述滑动件的部件; 伸长在从所述平台隔开的位置从所述基站可移动地支撑压缩臂（84），所述臂被操作以压缩所述载玻片和所述紧密接触在一起保持组件; 和一个保持组件安装机构（86），以便安装定位在所述保持组件到所述滑动件（14）而压缩所述臂（84）压缩所述载玻片（14）和所述保持组件在一起。

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