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91. 发明公开

EP2290027A3 Aqueous pressure-sensitive adhesive composition, production method therefor and pressure-sensitive adhesive tape using the composition 审中-公开
标题翻译：水性压敏粘合剂组合物，其制备方法和含有该组合物的粘合带
公开(公告)号：EP2290027A3
公开(公告)日：2011-04-27
申请号：EP10013022.8
申请日：2002-12-02
申请人： PERMACEL , Nitto Denko Corporation
发明人： Contrada, Svetlana, I. , Nakamura, Koichi , Hamblin, David R., Jr.
IPC分类号： C09J7/04 , C09J7/02 , C09J133/08
CPC分类号： C09J133/14 , C08G2170/40 , C08L33/04 , C08L33/26 , C08L65/04 , C08L2666/04 , C09J7/385 , C09J133/10 , C09J2201/606 , C09J2400/283 , Y10T428/28 , Y10T428/2891
摘要： A pressure-sensitive adhesive composition comprising a water-soluble polymer A, a water-insoluble component B, a water-incompatible solvent C that dissolves the water-insoluble component B and is incompatible with water, a water-soluble plasticizer D, and water, wherein the pressure-sensitive adhesive composition in a dry state has water solubility according to Technical Association of The Pulp and Paper Industry Useful Method 213 (TAPPI UM 213). Also disclosed are a method for producing a pressure-sensitive adhesive composition according to the present invention, comprising the steps of: preliminarily preparing a true nonaqueous solution of a water-insoluble component B in a water-incompatible solvent C, and mixing the true nonaqueous solution with an aqueous solution of at least one member selected from the group consisting of a water-soluble polymer A and a water-soluble plasticizer D, and a pressure-sensitive adhesive and a pressure-sensitive adhesive tape that use the composition.

92. 发明公开

EP2290027A2 Aqueous pressure-sensitive adhesive composition, production method therefor and pressure-sensitive adhesive tape using the composition 审中-公开
标题翻译：水性压敏粘合剂组合物，其制备方法和含有该组合物的粘合带
公开(公告)号：EP2290027A2
公开(公告)日：2011-03-02
申请号：EP10013022.8
申请日：2002-12-02
申请人： PERMACEL , Nitto Denko Corporation
发明人： Contrada, Svetlana, I. , Nakamura, Koichi , Hamblin, David R., Jr.
IPC分类号： C09J7/04 , C09J7/02 , C09J133/08
CPC分类号： C09J133/14 , C08G2170/40 , C08L33/04 , C08L33/26 , C08L65/04 , C08L2666/04 , C09J7/385 , C09J133/10 , C09J2201/606 , C09J2400/283 , Y10T428/28 , Y10T428/2891
摘要： A pressure-sensitive adhesive composition comprising a water-soluble polymer A, a water-insoluble component B, a water-incompatible solvent C that dissolves the water-insoluble component B and is incompatible with water, a water-soluble plasticizer D, and water, wherein the pressure-sensitive adhesive composition in a dry state has water solubility according to Technical Association of The Pulp and Paper Industry Useful Method 213 (TAPPI UM 213). Also disclosed are a method for producing a pressure-sensitive adhesive composition according to the present invention, comprising the steps of: preliminarily preparing a true nonaqueous solution of a water-insoluble component B in a water-incompatible solvent C, and mixing the true nonaqueous solution with an aqueous solution of at least one member selected from the group consisting of a water-soluble polymer A and a water-soluble plasticizer D, and a pressure-sensitive adhesive and a pressure-sensitive adhesive tape that use the composition.
摘要翻译：一种压敏粘合剂组合物，包括水溶性聚合物A，水不溶性组分B，一个水不相容的溶剂C确实溶解不溶于水的组分B和与水，水溶性增塑剂D，和水不相容，在干燥状态下worin压敏粘合剂组合物具有水溶性gemäß到的纸浆和造纸工业实用方法213技术协会（TAPPI UM 213）。所以游离缺失盘是用于制造压敏粘合剂组合物雅丁在本发明中，包含以下步骤的方法：预先在与水不相容的溶剂C制备的水不溶性组分B的真实非水溶液中，并且混合的真实非水与溶液在选自水溶性聚合物A和水溶性增塑剂，d中的至少一个构件，以及一个压敏粘合剂和压敏粘合带的wässrige溶液做了使用该组合物。

93. 发明授权

EP1539060B1 MULTI-MATERIAL CONSTRICTION DEVICE FOR FORMING STOMA OPENING 有权
标题翻译：几种材料的收缩，以形成人造口开口
公开(公告)号：EP1539060B1
公开(公告)日：2010-09-08
申请号：EP03771527.3
申请日：2003-07-24
申请人： Obesica AG
发明人： FORSELL, Peter
IPC分类号： A61F5/00 , A61L27/50
CPC分类号： A61F5/003 , A61B17/1322 , A61B17/135 , A61B2017/00831 , A61F5/005 , A61L27/10 , A61L27/306 , A61L31/088 , A61L31/10 , C08L65/04
摘要： An implantable constriction device for forming a restricted stoma opening in the stomach or esophagus of a patient comprises an elongate composite structure adapted to constrict the stomach or esophagus of the patient. The elongate composite structure is composed of a base material, such as hard silicone, making the composite structure self-supporting. Property improving means is provided for improving at least one physical property of the composite structure other than self-supporting properties, such as fatigue resistance, liquid impermeability, aggressive body cells resistance, anti-friction properties and lifetime.

94. 发明公开

EP2206526A2 Implantat und Verfahren zur Herstellung desselben 审中-公开
公开(公告)号：EP2206526A2
公开(公告)日：2010-07-14
申请号：EP09175779.9
申请日：2009-11-12
申请人： Biotronik VI Patent AG
发明人： Bayer, Ullrich , Becher, Bärbel , Block, Bernd , Lootz, Daniel
IPC分类号： A61L31/02 , A61L31/14
CPC分类号： A61L31/022 , A61L31/10 , A61L31/148 , A61L2420/08 , C23C22/34 , C23C22/60 , C08L65/04
摘要： Die vorliegenden Erfindung beschreibt ein Verfahren zur Herstellung eines Implantats, insbesondere einer intraluminalen Endoprothese, wobei das Grundmaterial des Körpers (5) des Implantats biodegradierbares metallisches Material, vorzugsweise Mg oder eine Mg-Legierung, aufweist. Das Verfahren umfasst die folgenden Schritte:
a) Bereitstellen des Körpers (5) des Implantats,
b) Aufbringen einer ersten Schicht (10) auf mindestens ein Teil der Oberfläche des Körpers (5), welche Ca- und P-lonen enthält, und
c) Aufbringen einer zweiten Schicht (20), welche zumindest teilweise für Ca- und P-Ionen durchlässig ist, derart, dass diese zumindest größtenteils die erste Schicht (10) überdeckt.
Es wird ferner ein entsprechendes Implantat beschrieben, bei dem durch die erfindungsgemäße Herstellung das Degradationsverhalten gesteuert werden kann.
摘要翻译：该方法包括提供植入体的体（5），即腔内内用假体，以及将包含钙离子和磷离子的第一层（10）施加到身体表面的一部分。施加对于钙离子和磷离子是部分可渗透的第二层（20），使得第二层主要覆盖第一层。在将第一层施加到身体表面的一部分之前施加第三层（30），其中第三层包含身体的基础材料的氢氧化物和/或氧化物和氟化物。对于由包含镁或镁合金的可生物降解金属材料制成的植入物也包括独立权利要求。

95. 发明公开

EP1935355A1 Schlauch für die enterale Ernährung 有权
标题翻译： Schlauchfürdie enteraleErnährung
公开(公告)号：EP1935355A1
公开(公告)日：2008-06-25
申请号：EP06025588.2
申请日：2006-12-11
申请人： N.V. Nutricia
发明人： Wolkenstörfer, Reinhold
IPC分类号： A61B17/34 , A61J15/00 , A61L29/16 , A61L31/10 , A61L29/08 , A61L31/08
CPC分类号： A61B17/3415 , A61B2017/00889 , A61B2017/00893 , A61J15/00 , A61J15/0026 , A61L29/06 , A61L29/085 , A61L29/16 , A61L2300/102 , A61L2300/104 , A61L2300/404 , C08L65/04
摘要： Ein PEG-Schlauch weist eine antimikrobielle Verbindung aus Metallionen freisetzenden Salzen auf.
摘要翻译：管道（10）包括布置在管道的表面区域（12）上或其表面区域（12）上的抗微生物或防腐化合物，以释放金属离子或胶体金属。优选的特征：如果管道，化合物均匀分布在材料中。将一层释放银或钛离子的材料施加在聚对二甲苯涂层上。聚对二甲苯涂层形成在管的外表面（16）和/或内表面（18）上。

96. 发明公开

EP1666555A3 Aqueous pressure-sensitive adhesive composition, production method therefor and pressure-sensitive adhesive tape using the composition 审中-公开
标题翻译：水性压敏粘合剂组合物，其制备方法和含有该组合物的粘合带
公开(公告)号：EP1666555A3
公开(公告)日：2007-04-18
申请号：EP06005309.7
申请日：2002-12-02
申请人： PERMACEL , NITTO DENKO CORPORATION
发明人： Contrada, Svetlana I. , Nakamura, Koichi , Hamblin, David R., Jr.
IPC分类号： C09J7/04 , C09J7/02 , C09J133/08
CPC分类号： C09J133/14 , C08G2170/40 , C08L33/04 , C08L33/26 , C08L65/04 , C08L2666/04 , C09J7/385 , C09J133/10 , C09J2201/606 , C09J2400/283 , Y10T428/28 , Y10T428/2891
摘要： The present invention relates to a water-soluble pressure-sensitive adhesive composition comprising
- 100 parts by weight of a water-soluble polymer A,
- 5 to 100 parts by weight of a water-insoluble component B,
- 5 to 500 parts by weight of a water-incompatible solvent C that dissolves the water-insoluble component B and is incompatible with water,
- 10 to 300 parts by weight of a water-soluble plasticizer D, and
- 100 to 800 parts by weight of water,
wherein the pressure-sensitive adhesive composition in a dry state has water solubility according to Technical Association of The Pulp and Paper Industry Useful Method 213 (TAPPI UM 213),
and to a method for producing same.

97. 发明公开

EP1700876A4 METHOD FOR IMPROVING THE HEAT STABILITY OF FILMS OF POLY-p-XYLYLENE OR DERIVATIVES THEREOF, AND POLY-p -XYLYLENE DERIVATIVES 有权
标题翻译：方法提高由聚对二甲苯膜或它们的衍生物和聚对苯二亚甲基衍生物的热稳定性
公开(公告)号：EP1700876A4
公开(公告)日：2006-12-20
申请号：EP03780945
申请日：2003-12-19
申请人： DAISANKASEI CO LTD
发明人： MARUYAMA HIROSHI , MOCHIZUKI TSUTOMU , INOUE TAKASHI
IPC分类号： C08G61/02 , C08L65/04
CPC分类号： C08G61/025 , C08G61/02 , C08G2261/3424 , C08L65/04
摘要： A method for improving the heat stability of a film of poly-p-xylylene or a derivative thereof as represented by the general formula (1), which comprises forming a film through chemical deposition from a raw material prepared by mixing a (2.2)-paracyclophane represented by the general formula (2) with an amino-(2.2)-paracyclophane represented by the general formula (3) and by which the heat resistance of the film can be improved without impairing the deposition properties or the economic efficiency; and poly-p-xylylene derivatives improved in heat resistance: (1) [wherein X1 and X2 are each hydrogen, lower alkyl, or halogeno, and they may be the same or different from each other; and n is a degree of polymerization], (2) [wherein X1 and X2 are each the same as defined for the general formula (1)], and (3) [wherein X3 is hydrogen or lower alkyl; and Y1 and Y2 are each hydrogen or amino, with the proviso that both of Y1 and Y2 must be not hydrogen].

98. 发明公开

EP1666555A2 Aqueous pressure-sensitive adhesive composition, production method therefor and pressure-sensitive adhesive tape using the composition 审中-公开
标题翻译：水性压敏粘合剂组合物，其制备方法和含有该组合物的粘合带
公开(公告)号：EP1666555A2
公开(公告)日：2006-06-07
申请号：EP06005309.7
申请日：2002-12-02
申请人： PERMACEL , NITTO DENKO CORPORATION
发明人： Contrada, Svetlana I. , Nakamura, Koichi , Hamblin, David R., Jr.
IPC分类号： C09J7/04 , C09J7/02 , C09J133/08
CPC分类号： C09J133/14 , C08G2170/40 , C08L33/04 , C08L33/26 , C08L65/04 , C08L2666/04 , C09J7/385 , C09J133/10 , C09J2201/606 , C09J2400/283 , Y10T428/28 , Y10T428/2891
摘要： The present invention relates to a water-soluble pressure-sensitive adhesive composition comprising

100 parts by weight of a water-soluble polymer A,
5 to 100 parts by weight of a water-insoluble component B,
5 to 500 parts by weight of a water-incompatible solvent C that dissolves the water-insoluble component B and is incompatible with water,
10 to 300 parts by weight of a water-soluble plasticizer D, and
100 to 800 parts by weight of water,
wherein the pressure-sensitive adhesive composition in a dry state has water solubility according to Technical Association of The Pulp and Paper Industry Useful Method 213 (TAPPI UM 213),

and to a method for producing same.
摘要翻译：本发明涉及一种水溶性的压敏粘合剂组合物，包括： - 将100重量份的水溶性聚合物A， - 5至100份（重量）的水不溶性组分B - 5〜500重量份一个水不相容的溶剂C所做的溶解不溶于水的组分B和与水不相容， - 10〜300重量份的水溶性增塑剂，d，以及 - 100〜800重量份的水，worin压力在干燥状态下敏感的粘合剂组合物具有水溶性gemäß所述的纸浆和造纸工业有用的方法213的技术协会（TAPPI UM 213），以及一种用于制造相同的方法。

99. 发明公开

EP1632254A1 Method of coating stents 失效转让
标题翻译： Verfahren zur Beschichtung von支架
公开(公告)号：EP1632254A1
公开(公告)日：2006-03-08
申请号：EP05254517.5
申请日：2005-07-20
申请人： Cordis Corporation
发明人： Akerman, Eugena A. , Cleeren, Dirk , Llanos, Gerard , Maryanoff, Cynthia A. , Papandreou, Georgios , Rion, William L. , Six, Karel , Todd, Thomas L.
IPC分类号： A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16
CPC分类号： A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16 , A61L2300/604 , A61L2420/08 , C08L65/04
摘要： An improved process for coating implantable medical devices utilizes a number of techniques for improving the stability of therapeutic agents contained within the coating.
In one embodiment, the process comprises:

(a) applying a primer coating on the implantable medical devices, including the application of a parylene layer and annealing the parylene layer to reduce autoxidation initiators;
(b) preparing a basecoat solution comprising polymers and a therapeutic agent and applying the basecoat solution to the implantable medical devices coated with parylene, the basecoat solution being prepared with and applied utilizing a process to reduce the presence and exposure of the basecoat solution to oxygen, raising the glass transition temperature of the therapeutic agent and creating a coating morphology to protect the therapeutic agent from autoxidation;
(c) preparing a topcoat solution comprising at least one polymer and applying the topcoat solution to the implantable medical devices coated with the basecoat solution, the topcoat solution being prepared with and applied utilizing a process to reduce the presence and exposure of the topcoat solution to oxygen, raising the glass transition temperature of the therapeutic agent and creating a coating morphology to protect the therapeutic agent from autoxidation; and
(d) finally processing the implantable medical devices, including inspecting, packaging and sterilizing the coated medical devices, the final processing including protecting the therapeutic agent from autoxidation, reducing the presence of and exposure of all materials to five radicals and reducing the presence of and exposure of all materials to oxygen.
摘要翻译：用于涂覆可植入医疗装置的改进方法利用许多技术来改善包含在涂层内的治疗剂的稳定性。在一个实施方案中，该方法包括：（a）在可植入医疗装置上施加底漆涂层，包括施加聚对二甲苯层并退火聚对二甲苯层以减少自动氧化引发剂; （b）制备包含聚合物和治疗剂的底涂层溶液，并将底涂层溶液施用于用聚对二甲苯涂覆的可植入医疗装置，所述底漆溶液通过使用并利用将底漆溶液存在和暴露于氧气的方法制备和应用提高治疗剂的玻璃化转变温度并产生涂层形态以保护治疗剂免于自动氧化; （c）制备包含至少一种聚合物的面漆溶液并将外涂层溶液涂覆到涂覆有底涂层溶液的可植入医疗装置上，所述面漆溶液通过制备并施加，以减少面漆溶液的存在和暴露于氧，提高治疗剂的玻璃化转变温度并产生涂层形态以保护治疗剂免于自氧化; （d）最后处理可植入医疗器械，包括检查，包装和消毒涂覆的医疗器械，最终加工包括保护治疗剂免于自动氧化，减少所有材料的存在和暴露于五个自由基，并减少并将所有材料暴露于氧气。

100. 发明公开

EP1466642A3 Drug delivery devices 审中-公开
标题翻译：药物递送装置
公开(公告)号：EP1466642A3
公开(公告)日：2005-11-30
申请号：EP04076743.6
申请日：1999-06-22
申请人： Bespak plc
发明人： Barnes, Paul , Lechner, Marc , Warby, Richard John
IPC分类号： A61M15/00 , B65D83/14 , C08L65/04
CPC分类号： B65D83/54 , A61M15/009 , C08L65/04
摘要： The invention relates to improvements to drugs delivery devices, in particular, those for dispensing a metered dose of medicament. There is provided apparatus (10, 110) for dispensing a medicament wherein at least a portion of one or more of the surfaces of components of the apparatus which come into contact with the medicament during storage or dispensing has a layer of a poly-para-xylylene polymer also known as parylene bonded to at least a portion thereof.

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