专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

91. 发明公开

EP1255725A2 5-AMINOLÄVULINSÄURE-FORMULIERUNG IN NICHTWÄSSRIGEN LÖSUNGSMITTELN 无效
标题翻译： 5-氨基乙酰丙酸表达的非水溶剂
公开(公告)号：EP1255725A2
公开(公告)日：2002-11-13
申请号：EP01911547.6
申请日：2001-01-29
申请人： Asat AG Applied Science & Technology
发明人： GANDER, Bruno , BUNKE, Antje , BURMEISTER, Gerd
IPC分类号： C07C229/00
CPC分类号： A61K31/197 , A61K9/0014 , A61K41/0061 , A61K47/10
摘要： The invention relates to compositions that contain 5-aminolevulinic acid and/or the derivatives thereof dissolved or dispersed in a non-aqueous liquid. The invention further relates to a two-chamber system that contains compositions of the 5-aminolevulinic acid and/or the derivatives thereof in which the active substances are stored in a non-aqueous phase and which are ready for use once mixed with an aqueous phase.

92. 发明公开

EP1140176A1 TRANSCUTANEOUS PHOTODYNAMIC TREATMENT OF TARGETED CELLS 审中-公开
标题翻译： DUAL共轭皮光动力FOR脂质体系统肿瘤靶向治疗
公开(公告)号：EP1140176A1
公开(公告)日：2001-10-10
申请号：EP00902416.7
申请日：2000-01-14
申请人： Light Sciences Corporation
发明人： CHEN, James
IPC分类号： A61K41/00
CPC分类号： A61K41/0057 , A61K41/0061 , A61K41/0071 , A61K47/6817 , A61K47/6835 , A61K47/6849 , A61K47/6867 , A61N5/062
摘要： The present invention is drawn to methods and compounds for photodynamic therapy (PDT) of a target tissue or compositions in a mammalian subject, using a light source that preferably transmits light to a treatment site transcutaneously. The method provides for administering to the subject a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. This targeted substance preferably selectively binds to the target tissue. Light at a wavelength or waveband corresponding to that which is absorbed by the targeted substance is then administered. The light intensity is relatively low, but a high total fluence is employed to ensure the activation of the targeted photosensitizing agent or targeted prodrug product. Transcutaneous PDT is useful in the treatment of specifically selected target tissues, such as vascular endothelial tissue, the abnormal vascular walls of tumors, solid tumors of the head and neck, tumors of the gastrointestinal tract, tumors of the liver, tumors of the breast, tumors of the prostate, tumors of the lung, nonsolid tumors, malignant cells of the hermatopoietic and lymphoid tissue and other lesions in the vascular system or bone marrow, and tissue or cells related to autoimmune and inflammatory disease.

93. 发明授权

EP1019037B1 DELTA-AMINOLÄVULINSÄURE ENTHALTENDES ARZNEIMITTEL 有权
标题翻译： δ-氨基乙酰丙酸含药物
公开(公告)号：EP1019037B1
公开(公告)日：2001-08-08
申请号：EP98952606.6
申请日：1998-09-21
申请人： Medac Gesellschaft für klinische Spezialpräparate mbH
发明人： HEISIG, Wolfgang , BACH, Ferdinand
IPC分类号： A61K31/195 , A61K47/02
CPC分类号： A61K9/0014 , A61K31/197 , A61K41/0061 , A61K47/02
摘要： The invention relates to a topically applied medicament for the integral diagnosis and/or treatment of tumours in hollow organs, with a delta -aminolevulinic acid base. The inventive medicament contains a physiologically compatible acid and sodium hydrogen phosphate as a buffer in addition to the active agent in an aqueous solution, and has a pH value of 4.8 to 5.2. The medicament is stable and particularly compatible.

94. 发明授权

EP0820432B1 ESTERS OF 5-AMINOLEVULINIC ACID AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY 有权转让
标题翻译：作者5-氨基乙酰丙酸AS化疗PHOTO认识的一种手段酯
公开(公告)号：EP0820432B1
公开(公告)日：2001-06-13
申请号：EP96905940.1
申请日：1996-03-08
申请人： PhotoCure ASA
发明人： GIERSKCKY, Karl, Erik , MOAN, Johan , PENG, Qian , STEEN, Harald , WARLOE, Trond , BJORSETH, Alf
IPC分类号： C07C229/22 , C07C227/18 , A61K31/195
CPC分类号： A61K49/0021 , A61K41/0061 , A61K49/0017 , C07C229/22 , Y10T436/145555

95. 发明公开

EP0820432A1 ESTERS OF 5-AMINOLEVULINIC ACID AS PHOTOSENSITIZING AGENTS IN PHOTOCHEMOTHERAPY 有权转让
标题翻译：作者5-氨基乙酰丙酸AS化疗PHOTO认识的一种手段酯
公开(公告)号：EP0820432A1
公开(公告)日：1998-01-28
申请号：EP96905940.0
申请日：1996-03-08
申请人： Photocure AS
发明人： GIERSKCKY, Karl, Erik , MOAN, Johan , PENG, Qian , STEEN, Harald , WARLOE, Trond , BJORSETH, Alf
IPC分类号： G01N33 , A61K31 , A61K41 , A61K49 , A61P35 , C07C227 , C07C229
CPC分类号： A61K49/0021 , A61K41/0061 , A61K49/0017 , C07C229/22 , Y10T436/145555
摘要： The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) R22N-CH2COCH2-CH2CO-OR1, (wherein R1 may represent alkyl optionally substituted by hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, oxo or fluoro groups and optionally interrupted by oxygen, nitrogen, sulphur or phosphorus atoms; and R2 represents a hydrogen atom or a group R1, and both R2 groups may be the identical or different), and their use in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body, and products and kits for performing the invention.

96. 发明授权

EP2722041B1 THERAPEUTIC AGENT FOR ALLERGIC RHINITIS 有权
公开(公告)号：EP2722041B1
公开(公告)日：2018-10-24
申请号：EP12801049.3
申请日：2012-06-15
申请人： SBI Pharmaceuticals Co., Ltd. , National Hospital Organization
发明人： TANAKA, Tohru , INOUE, Katsushi , TAKAHASHI, Kiwamu , ISHII, Takuya , NUMATA, Tsutomu , SHIBUYA, Mariko , SUZUKI, Takeshi
IPC分类号： A61K31/197 , A61K9/06 , A61K9/08 , A61K41/00 , A61P11/02 , A61P37/08 , A61N5/06
CPC分类号： A61N5/062 , A61K9/0043 , A61K9/06 , A61K41/0061 , F04C2270/0421
摘要： Provided is a therapeutic agent capable of treating allergic rhinitis in a safe, simple, and noninvasive manner substantially without side effects and physical distress to patients. Provided is a therapeutic agent for allergic rhinitis for 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) comprising 5-aminolevulinic acid (ALA) or a derivative thereof, or a salt of the 5-aminolevulinic acid or the derivative as an active ingredient, and used in ALA-PDT in which light having a wavelength of 400 nm to 700 nm is irradiated; and particularly provided is a therapeutic agent for allergic rhinitis in a locally applied solution form, a water-soluble ointment-dissolved form, a jelly-dissolved form, or the like. The therapeutic agent does not require the conduct of 5-aminolevulinic acid-based photodynamic diagnosis (ALA-PDD) for detecting a site of protoporphyrin IX (PpIX) accumulation radiating light having a wavelength of 610 nm to 650 nm under irradiation of excitation light having a wavelength of 380 nm to 420 nm before ALA-PDT.

97. 发明授权

EP2932967B1 USE OF A PHOTOSENSITIVE AGENT CAPABLE OF PRODUCING REACTIVE OXYGEN SPECIES IN THE PRODUCTION OF A DRUG FOR THE PHOTODYNAMIC THERAPY OF A DISEASE RELATED TO STEM CELLS, IN VITRO USE, AND PHARMACEUTICAL COMPOSITION 有权转让
公开(公告)号：EP2932967B1
公开(公告)日：2018-08-29
申请号：EP13855732.7
申请日：2013-11-11
申请人： Universidad Autónoma de Madrid , Consejo Superior de Investigaciones Cientificas
发明人： ESPADA REGALADO, Jesús , CARRASCO CERRO, Elisa , CALVO SANCHEZ, María Inmaculada , BLAZQUEZ-CASTRO, Alfonso , JUARRANZ DE LA FUENTE, Angeles
IPC分类号： A61K31/409 , A61P17/00 , A61K31/197 , A61K31/221
CPC分类号： A61K41/0071 , A61K8/44 , A61K8/492 , A61K8/494 , A61K31/409 , A61K41/0061 , A61K2800/10 , A61Q19/00
摘要： The invention relates to the use of a photosensitive agent, or the precursor thereof, capable of producing reactive oxygen species (ROS) in the production of a drug that can be used for the photodynamic therapy (PDT)-based treatment of a disease related to a patient's stem cells, preferably epidermal stem cells.

98. 发明公开

EP3352736A1 HYDROPHILIC GEL FOR TOPICAL DELIVERY OF 5-AMINOLEVULINIC ACID 审中-公开
公开(公告)号：EP3352736A1
公开(公告)日：2018-08-01
申请号：EP16775525.5
申请日：2016-09-20
申请人： Zimmer Biotech GmbH
发明人： SOLIOZ, André , STOWASSER, Frank , ZIMMER, Armin
IPC分类号： A61K9/00 , A61K41/00 , A61K9/06 , A61K47/36
CPC分类号： A61K41/0061 , A61K9/0009 , A61K9/0014 , A61K9/06 , A61K31/198 , A61K47/22 , A61K47/36 , A61P17/00
摘要： The present invention relates to a pharmaceutical topical gel solution that contains 5-aminolevulinic acid (5-ALA) and an aqueous low viscous gel matrix. This invention also relates to a pharmaceutical preparation containing this composition. The formulation of this type can be used in photodynamic therapy as well as in the photodynamic detection of abnormally proliferating cells.

99. 发明公开

EP3108884A4 COMPOSITION FOR PREVENTION OR TREATMENT OF TREATMENT-RESISTANT CANCER 无效
标题翻译： ZUSAMMENSETZUNG ZURPRÄVENTIONOER BEHANDLUNG VON BEHANDLUNGS RETESISTENTEM KREBS
公开(公告)号：EP3108884A4
公开(公告)日：2017-09-20
申请号：EP15752334
申请日：2015-02-16
申请人： SBI PHARMACEUTICALS CO LTD , OSAKA MEDICAL AND PHARMACEUTICAL COLLEGE
发明人： ISHIKAWA TOSHIHISA , KUROIWA TOSHIHIKO , KAJIMOTO YOSHINAGA , FUJISHIRO TAKAHIRO , KIMURA SEIGO , MIYATAKE SHIN-ICHI , TANAKA TOHRU
IPC分类号： A61K31/22 , A61K31/235 , A61K31/506 , A61K31/517 , A61K31/5377 , A61K41/00 , A61K45/00 , A61K45/06 , A61N5/06 , A61P35/00 , A61P43/00
CPC分类号： A61K41/0061 , A61K31/22 , A61K31/235 , A61K31/506 , A61K31/517 , A61K31/5377 , A61K45/06 , A61N5/062 , A61K2300/00

100. 发明授权

EP2722059B1 Photodynamic diagnostics of tissue fluids caused by oncological pathology 有权
标题翻译：由肿瘤病理学引起的组织液的光动力学诊断
公开(公告)号：EP2722059B1
公开(公告)日：2017-05-17
申请号：EP13189606.0
申请日：2013-10-22
申请人： I.I. Lazeriu ir Bangu Medicinos Moksliné Klinika , Nacionalinis vézio institutas
发明人： Plesniene, Laima , Plesnys, Albinas , Vaisnoras, Rimantas
IPC分类号： A61K49/00 , G01N33/574
CPC分类号： A61K41/0061 , A61K41/0071 , A61K49/0036 , G01N33/574

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式