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1. 发明公开

EP3603486A3 SURGICAL MICROSCOPE WITH INTEGRATED OPTICAL COHERENCE TOMOGRAPHY AND DISPLAY SYSTEMS 审中-实审转让
公开(公告)号：EP3603486A3
公开(公告)日：2020-04-15
申请号：EP19191929.9
申请日：2016-06-07
申请人： Novartis AG
发明人： YU, Lingfeng , SHOFMAN, Vadim , HEEREN, Tammo , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13
摘要： An ophthalmic surgical microscope includes an OCT system comprises an OCT light source for generating an OCT imaging beam, a beam coupler for directing the OCT imaging beam along an optical path to a patient's eye, wherein at least a portion of the OCT imaging beam reflected by the patient's eye is returned to the OCT system, and wherein the OCT system is operable to generate an OCT image based on the reflected portion of the OCT imaging beam; an imaging unit for generating a fundus image of the patient's eye; a tracking system that processes the fundus image to calculate a location of a surgical instrument inserted into the patient's eye. The OCT system further comprises a beam scanner for directing the OCT imaging beam to a particular region on a plane substantially orthogonal with the optical path within the patient's eye, the particular region including the calculated location of the surgical instrument inserted into the patient's eye. The OCT system comprises a real-time data projection unit for projecting the OCT image generated by the OCT system and a first beamsplitter for directing the OCT image projected by the real-time data projection to a first eyepiece of the ophthalmic surgical microscope such that the OCT image projected by the real-time data projection unit is viewable through the first eyepiece.

2. 发明公开

EP3603486A2 SURGICAL MICROSCOPE WITH INTEGRATED OPTICAL COHERENCE TOMOGRAPHY AND DISPLAY SYSTEMS 审中-实审转让
公开(公告)号：EP3603486A2
公开(公告)日：2020-02-05
申请号：EP19191929.9
申请日：2016-06-07
申请人： Novartis AG
发明人： YU, Lingfeng , SHOFMAN, Vadim , HEEREN, Tammo , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13
摘要： An ophthalmic surgical microscope includes an OCT system comprises an OCT light source for generating an OCT imaging beam, a beam coupler for directing the OCT imaging beam along an optical path to a patient's eye, wherein at least a portion of the OCT imaging beam reflected by the patient's eye is returned to the OCT system, and wherein the OCT system is operable to generate an OCT image based on the reflected portion of the OCT imaging beam; an imaging unit for generating a fundus image of the patient's eye; a tracking system that processes the fundus image to calculate a location of a surgical instrument inserted into the patient's eye. The OCT system further comprises a beam scanner for directing the OCT imaging beam to a particular region on a plane substantially orthogonal with the optical path within the patient's eye, the particular region including the calculated location of the surgical instrument inserted into the patient's eye. The OCT system comprises a real-time data projection unit for projecting the OCT image generated by the OCT system and a first beamsplitter for directing the OCT image projected by the real-time data projection to a first eyepiece of the ophthalmic surgical microscope such that the OCT image projected by the real-time data projection unit is viewable through the first eyepiece.

3. 发明授权

EP3265995B1 OCT IMAGE MODIFICATION 有权转让
公开(公告)号：EP3265995B1
公开(公告)日：2019-03-20
申请号：EP16726656.8
申请日：2016-05-16
申请人： Novartis AG
发明人： YU, Lingfeng , REN, Hugang , PAPAC, Michael J.
IPC分类号： G06T5/00 , G06T7/70

4. 发明授权

EP3082569B1 MARKER-BASED TOOL TRACKING 有权转让
公开(公告)号：EP3082569B1
公开(公告)日：2019-02-27
申请号：EP14872305.9
申请日：2014-12-05
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： A61B3/12 , A61B3/14 , A61B18/22 , A61F9/007 , A61B3/00 , A61B3/10

5. 发明公开

EP3265008A1 SURGICAL TOOL TRACKING TO CONTROL SURGICAL SYSTEM 有权转让
标题翻译：手术工具跟踪控制手术系统
公开(公告)号：EP3265008A1
公开(公告)日：2018-01-10
申请号：EP16709863.1
申请日：2016-02-23
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： A61B34/00 , A61F9/007 , G06F3/01 , A61B34/20 , A61B17/00 , A61B90/00
CPC分类号： A61F9/007 , A61B3/13 , A61B34/20 , A61B34/25 , A61B90/20 , A61B2017/00207 , A61B2034/2048 , A61B2034/2055 , A61B2034/2065 , A61B2034/254 , A61B2090/371 , A61B2090/372 , A61F9/00736 , G06F1/163 , G06F3/011 , G06F3/017 , G06F3/0482
摘要： A surgical system uses a surgical tool as a control input. A tracking unit tracks a motion of the surgical tool, and a processing unit for processes the motion of the surgical tool to obtain a temporal spatial information of the surgical tool. The control unit further comprises a control input unit with a number of control commands. The control input unit associates the temporal spatial information of the surgical tool with a corresponding control command.

6. 发明公开

EP3512407A1 SUBTRACTIVE EN FACE OPTICAL COHERENCE TOMOGRAPHY IMAGING 审中-实审转让
公开(公告)号：EP3512407A1
公开(公告)日：2019-07-24
申请号：EP17777962.6
申请日：2017-09-05
申请人： Novartis AG
发明人： CHARLES, Steven , YU, Lingfeng , REN, Hugang
IPC分类号： A61B3/10 , A61B3/13

7. 发明授权

EP3230949B1 SYSTEMS AND METHODS FOR DUAL VITREOUS AND RETINA IMAGING 有权转让
公开(公告)号：EP3230949B1
公开(公告)日：2019-05-01
申请号：EP16708258.5
申请日：2016-02-10
申请人： Novartis AG
发明人： YU, Lingfeng , REN, Hugang
IPC分类号： G06T5/50

8. 发明公开

EP3360112A1 FAST AND AUTOMATED SEGMENTATION OF LAYERED IMAGE WITH HEURISTIC GRAPH SEARCH 有权转让
公开(公告)号：EP3360112A1
公开(公告)日：2018-08-15
申请号：EP16819664.0
申请日：2016-12-02
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： G06T7/13 , G06T7/162 , G06T7/181
CPC分类号： G06T7/181 , G06T7/13 , G06T7/162 , G06T7/90 , G06T2207/10101 , G06T2207/10132 , G06T2207/20016 , G06T2207/30041
摘要： A method of processing an ophthalmic image includes: taking an image of an ophthalmic region involving an ophthalmic layer by an imaging system; constructing an image graph, comprising nodes connected by links and detected image data by an image processor; and performing a heuristic graph-search for a path on the image graph that corresponds to an image of the ophthalmic layer by assigning at least one of link-costs to links of the image graph and node-costs to nodes of the image graph; assigning heuristic-costs to at least one of the nodes and the links; creating extended paths by extending a selected path with extension links; determining path-costs of the extended paths by combining heuristic costs and at least one of link-costs and node-costs assigned to the extension-links; and selecting the extended path with the smallest path-cost.

9. 发明公开

EP3265995A1 OCT IMAGE MODIFICATION 有权转让
标题翻译： OCT图像修改
公开(公告)号：EP3265995A1
公开(公告)日：2018-01-10
申请号：EP16726656.8
申请日：2016-05-16
申请人： Novartis AG
发明人： YU, Lingfeng , REN, Hugang , PAPAC, Michael J.
IPC分类号： G06T5/00
CPC分类号： G06T5/001 , A61B3/102 , A61B3/13 , A61B90/20 , G02B21/0012 , G06T5/005 , G06T7/70 , G06T2207/10101 , G06T2207/30164
摘要： According to some examples, a method for Optical Coherence Tomography (OCT) image modification includes receiving an OCT image of a region of interest of patient tissue from an OCT imaging system configured to direct an OCT beam at the region of interest and determining that an OCT transparent instrument is within the OCT image. The method further includes detecting an artifact in the OCT image, the artifact resulting from the OCT transparent instrument being within a path of the OCT beam. In response to detecting the artifact, the method further includes creating an image modification plan to remove the artifact from the OCT image. The method further includes executing the image modification plan to remove the artifact from the OCT image.

10. 发明公开

EP3131455A1 OPHTHALMIC IMAGING SYSTEM WITH AUTOMATIC RETINAL FEATURE DETECTION 有权转让
标题翻译：汽车零部件ABBILDUNGSSYSTEM MIT AUTOMATISCHER NETZHAUTMERKMALSERKENNUNG
公开(公告)号：EP3131455A1
公开(公告)日：2017-02-22
申请号：EP15808902.9
申请日：2015-05-15
申请人： Novartis AG
发明人： REN, Hugang , YU, Lingfeng
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/0025 , A61B3/12 , G06T7/0012 , G06T2207/10101 , G06T2207/30041
摘要： A method of automatically detecting a retinal feature using an ophthalmic imaging system can include: acquiring an optical coherence tomography (OCT) image of a retina; segmenting the OCT image; generating a metric based on the segmented OCT image; detecting the retinal feature based on the metric; and providing an indication of the detected retinal feature to a user. An ophthalmic imaging system can include: an OCT system configured to acquire an image of a retina; a computing device coupled to the OCT system and configured to segment the image, generate a metric based on the segmented image, and detect a retinal feature based on the metric; and an audio/visual/tactile device in communication with the computing device and configured to provide at least one of an audio, visual, and tactile indication of the detected retinal feature to a user.
摘要翻译：使用眼科成像系统自动检测视网膜特征的方法可以包括：获取视网膜的光学相干断层摄影（OCT）图像; 分割OCT图像; 基于分割的OCT图像生成度量; 基于度量检测视网膜特征; 以及向用户提供检测到的视网膜特征的指示。眼科成像系统可以包括：OCT系统，被配置为获取视网膜的图像; 耦合到所述OCT系统并被配置为分割所述图像的计算设备，基于所述分割的图像生成度量，以及基于所述度量来检测视网膜特征; 以及与计算设备通信并被配置为向用户提供检测到的视网膜特征的音频，视觉和触觉指示中的至少一个的音频/视觉/触觉设备。

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