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    • 1. 发明授权
    • Method and apparatus of mass-correlated pulsed extraction for a time-of-flight mass spectrometer
    • 飞行时间质谱仪质量相关脉冲提取的方法和装置
    • US06518568B1
    • 2003-02-11
    • US09589480
    • 2000-06-07
    • Viatcheslav V. KovtounRobert J. Cotter
    • Viatcheslav V. KovtounRobert J. Cotter
    • H01J4840
    • H01J49/40
    • A time-of-flight mass spectrometer includes a sample holder for a sample and an ionizer for ionizing the sample to form ions. A first element is spaced downstream from the sample holder, a second element is spaced downstream from the first element, and a drift region is downstream of the second element. An electric field is established between the sample holder and the first element at a time subsequent to ionizing the sample in order to extract the ions. A time-dependent and mass-correlated electric field is established between at least one of: (a) the first element and the second element, and (b) the sample holder and the first element. In turn, a detector detects the ions.
    • 飞行时间质谱仪包括用于样品的样品保持器和用于电离样品以形成离子的离子发生器。 第一元件与样品保持器的下游间隔开,第二元件与第一元件的下游间隔开,漂移区域位于第二元件的下游。 在电离样品之后的时间,在样品保持器和第一元件之间建立电场以提取离子。 在(a)第一元件和第二元件中的至少一个以及(b)样品保持器和第一元件中的至少一个之间建立时间依赖和质量相关的电场。 反过来,检测器检测离子。
    • 2. 发明授权
    • Ion acceleration apparatus and method
    • US06469296B1
    • 2002-10-22
    • US09484374
    • 2000-01-14
    • Stuart C. HansenJames Foote
    • Stuart C. HansenJames Foote
    • H01J4840
    • H01J49/403
    • An ion acceleration apparatus and method, and a mass spectrometer using the apparatus and method, require only a single pulse generator for the collection and acceleration of ions. The apparatus, method and mass spectrometer are useful in time-of-flight mass spectrometry (TOFMS). The apparatus, method and spectrometer save on manufacturing costs and complexity, without compromising measurement sensitivity or reliability. The ion acceleration apparatus comprises a plurality of conductive plates comprising a pulser electrode, three grids and preferably, a plurality of frames units, in a stacked relationship. The pulser electrode and a third grid form the outside ends of the ion acceleration apparatus. The plates of the stack are spaced apart and electrically insulated from one another. A power source provides fill, pulse and bias voltages to the plates. The power source comprises a pulse generator that provides fill and pulse voltages to the pulser electrode and to a first grid that is adjacent to the pulser electrode. A second grid is electrically connected to ground potential and is between the first grid and the plurality of guard frames. The power source further comprises a voltage source for supplying a fixed high voltage bias to the third grid and preferably to the frame units. During the fill period, analyte ions from an ion source are collected in a fill region between the pulser electrode and the first grid. The pulser electrode and first grid are supplied with a small magnitude voltage of a polarity opposite to a polarity of a charge of the analyte ions. During the pulse period, the analyte ions are induced to move from the fill region and into an acceleration region by the application of the pulse voltage to the pulse electrode and the first grid. The pulse voltage is a large magnitude voltage of the same polarity as the polarity of the charge on the analyte ions. A field produced by the fixed voltage bias applied to the third grid and guard frames accelerates the analyte ions once they enter the acceleration region.