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1. 发明授权

US08482280B2 System and method for propeller magnetic resonance imaging with non-parallel bladelets 有权
标题翻译：具有非平行叶片的螺旋桨磁共振成像系统和方法
公开(公告)号：US08482280B2
公开(公告)日：2013-07-09
申请号：US12693100
申请日：2010-01-25
申请人： Donglai Huo , James Grant Pipe
发明人： Donglai Huo , James Grant Pipe
IPC分类号： G01R33/4818 , G01R33/4824 , G01R33/5611
CPC分类号： G01R33/5617 , G01R33/4824 , G01R33/5611 , G01R33/56341
摘要： A system and method include a computer readable storage medium having stored thereon a computer program comprising instructions which when executed by a computer cause the computer to apply a first plurality of radio frequency (RF) pulses during a first repetition time (TR) interval of a magnetic resonance (MR) pulse sequence. The instructions also cause the computer to apply a first plurality of gradient pulses and acquire the MR data during application of each gradient pulse of the first plurality of gradient pulses between an adjacent pair of RF pulses of the first plurality of RF pulses. Each gradient pulse of the first plurality of gradient pulses is configured to allow acquisition of MR data for a respective first bladelet passing through a center of k-space, wherein the first bladelets are non-parallel with each other. The instructions also cause the computer to reconstruct the acquired MR data into an image.
摘要翻译：一种系统和方法包括其上存储有计算机程序的计算机可读存储介质，所述计算机程序包括当计算机执行时使计算机在第一重复时间（TR）间隔期间施加第一多个射频（RF）脉冲的指令，磁共振（MR）脉冲序列。所述指令还使得所述计算机在所述第一多个RF脉冲的相邻的一对RF脉冲之间的所述第一多个梯度脉冲的每个梯度脉冲的应用期间，施加第一多个梯度脉冲并获取MR数据。第一多个梯度脉冲的每个梯度脉冲被配置为允许获取通过k空间的中心的相应的第一叶片的MR数据，其中第一叶片彼此不平行。指令还使计算机将所获取的MR数据重构成图像。

2. 发明申请

WO2021245024A1 MAGNETIC RESONANCE IMAGING WITH ZERO ECHO TIME AND SLICE SELECTION 审中-公开
公开(公告)号：WO2021245024A1
公开(公告)日：2021-12-09
申请号：PCT/EP2021/064543
申请日：2021-05-31
申请人： CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) , UNIVERSITAT POLITÈCNICA DE VALÈNCIA
发明人： GALVE CONDE, Fernando , ALGARÍN GUISADO, José Miguel , BORREGUERO MORATA, José , BENLLOCH BAVIERA, Jose María
IPC分类号： G01R33/48 , G01R33/4816 , G01R33/4824 , G01R33/4833
摘要： The invention provides a novel radio frequency sequence, suitable for performing Magnetic Resonance Imaging (MRI) of 2-dimensional (2D) slices (rather than 3- dimensional volumes) of samples exhibiting short magnetization coherence times (i.e. hard tissues). The SS-ZTE pulse sequence comprises the following steps: a) magnetizing all spins in the sample from a longitudinal direction to the transverse plane; b) exciting the 2D slice of interest, which comprises the selective locking of said 2D sample slice magnetization while spoiling the magnetization in the rest of sample volume; c) making the magnetization of the selected 2D slice impervious to reconfigurations of the magnetic field gradients from slice selection to encoding and readout; d) reading out of the free induction decay signal of the sample; e) repeating steps (a-d) with different readout directions, so as to gather a corresponding number of radial spokes of the plane defined by the 2D sample slice.

3. 发明申请

WO2021081309A2 ARTEFACT REDUCTION IN MAGNETIC RESONANCE IMAGING 审中-公开
公开(公告)号：WO2021081309A2
公开(公告)日：2021-04-29
申请号：PCT/US2020/057027
申请日：2020-10-23
申请人： HYPERFINE RESEARCH, INC.
发明人： LAZARUS, Carole , O'HALLORAN, Rafael , DYVORNE, Hadrien, A.
IPC分类号： G01R33/44 , G01R33/565 , G01R33/385 , G01R33/48 , G01R33/3628 , G01R33/3806 , G01R33/445 , G01R33/4818 , G01R33/4822 , G01R33/4824 , G01R33/5608 , G01R33/5611 , G01R33/56509 , G01R33/56518 , G06T11/006 , G06T11/008
摘要： A method of operating a low-field magnetic resonance imaging (MRI) system, the method comprising: obtaining an initial set of k-space phase-encoding coordinates; generating a sampling path through at least some of the k-space phase-encoding coordinates in the initial set to mitigate impact of eddy currents on operation of the low-field MRI system; and operating the low-field MRI system using a pulse sequence in accordance with the sampling path to obtain spatial frequency data for generating one or more magnetic resonance (MR) images of a subject.

4. 发明申请

WO2021259494A1 METHOD AND DEVICE FOR ACQUIRING AND RECONSTRUCTING A SEQUENCE OF DIFFUSION-WEIGHTED MAGNETIC RESONANCE IMAGES COVERING A VOLUME 审中-公开
公开(公告)号：WO2021259494A1
公开(公告)日：2021-12-30
申请号：PCT/EP2020/068061
申请日：2020-06-26
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
发明人： FRAHM, Jens , VOIT, Dirk , KALENTEV, Oleksandr
IPC分类号： G01R33/563 , G01R33/48 , G01R33/483 , G01R33/561 , G01R33/4824 , G01R33/4835 , G01R33/5611 , G01R33/56341
摘要： A method for creating sequences of diffusion-weighted magnetic resonance (MR) images of an object under investigation, wherein each of said sequences of MR images represents the same series of cross-sectional slices covering a volume of the object, comprises the steps of (a) providing multiple sequences of sets of image raw data being collected with the use of at least one radiofrequency receiver coil of a magnetic resonance imaging (MRI) device, wherein each set of image raw data includes a plurality of data samples being generated with a combined diffusion-weighted spin-echo and single-shot stimulated-echo sequence with diffusion-encoding gradients having at least two different strengths and at least three different directions, wherein one of the sequences of sets of raw data is generated with diffusion-encoding gradients of zero strength or lower strength and further sequences of sets of raw data are generated with diffusion-encoding gradients of higher strength, (b) subjecting the sequence of sets of image raw data generated with diffusion-encoding gradients of zero strength or lower strength to a regularized nonlinear inverse reconstruction process to provide a sequence of MR images with no or lower diffusion weighting, and (c) subjecting the sequences of sets of image raw data with diffusion-encoding gradients of higher strengths to a linear inverse reconstruction process to provide sequences of MR images with higher diffusion weighting, each of the images representing one of the cross-sectional slices and being created by using the sensitivity of the at least one receiver coil determined in step (b) for the same cross-sectional slice. Furthermore, an MRI device for creating a sequence of diffusion-weighted MR images of an object under investigation is described.

5. 发明申请

WO2021254861A1 ESTIMATION OF B0 INHOMOGENEITIES FOR IMPROVED ACQUISITION AND/OR RECONSTRUCTION OF MAGNETIC RESONANCE IMAGES 审中-公开
公开(公告)号：WO2021254861A1
公开(公告)日：2021-12-23
申请号：PCT/EP2021/065586
申请日：2021-06-10
申请人： KONINKLIJKE PHILIPS N.V.
发明人： RUDRAPATNA, Umesh, Suryanarayana , NEELAVALLI, Jaladhar , GOPALAKRISHNAN, Karthik , NAGARAJ, Suthambhara , BAJAJ, Naveen , VAKKACHI KANDI, Rupesh
IPC分类号： G01R33/24 , G01R33/3875 , G01R33/54 , G01R33/565 , G06N3/02 , A61B5/055 , G01R33/48 , G01R33/483 , G01R33/561 , G06N3/08 , G01R33/56 , G01R33/243 , G01R33/4824 , G01R33/4835 , G01R33/543 , G01R33/5608 , G01R33/5616 , G01R33/56509 , G01R33/56518 , G01R33/56563 , G06N20/10 , G06N20/20 , G06N3/0454 , G06N3/084 , G06N5/003
摘要： Disclosed herein is a medical system (100, 300, 500) comprising a memory (110) storing machine executable instructions (120) and a B0 field estimation module (126); and a computational system (106). Execution of the machine executable instructions causes the computational system to receive (200) an initial magnetic resonance image (122) that comprises a magnitude component and is descriptive of a first region (326) of interest of a subject (118). Execution of the machine executable instructions further causes the computational system to perform at least one iteration of the following: receive (202) subsequent k-space data (124) descriptive of a subsequent region of interest (328) of the subject; calculate (204) an estimated B0 field mapping (128) for the subsequent region of interest from the initial magnetic resonance image by inputting the initial magnetic resonance image into the B0 field estimation module; and reconstruct (206) a corrected magnetic resonance image (130) from the subsequent k-space data and the estimated B0 field mapping.

6. 发明申请

WO2020198475A1 PROPELLER ECHO PLANAR TIME-RESOLVED IMAGING WITH DYNAMIC ENCODING 审中-公开
公开(公告)号：WO2020198475A1
公开(公告)日：2020-10-01
申请号：PCT/US2020/024964
申请日：2020-03-26
申请人： THE GENERAL HOSPITAL CORPORATION
发明人： SETSOMPOP, Kawin , FAIR, Merlin, John Casper
IPC分类号： A61B5/00 , G06T11/00 , G01R33/48 , G01R33/56 , G01R33/561 , G01R33/565 , A61B2560/0223 , A61B5/0002 , A61B5/0042 , A61B5/055 , G01R33/34 , G01R33/4824 , G01R33/5616 , G01R33/56509
摘要： Magnetic resonance imaging ("MRI") using a PROPELLER echo-planar time- resolved imaging with dynamic encoding ("PEPTIDE") scheme is described. The PEPTIDE scheme combines a PROPELLER-style trajectory with an echo-planar time-resolved imaging ("EPTI") acquisition framework, along with dynamic-updating of sensitivity- encoding information.

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