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    • 8. 发明申请
    • Compositions and methods for glycogen synthesis
    • 糖原合成的组成和方法
    • US20050176827A1
    • 2005-08-11
    • US10926849
    • 2004-08-26
    • Steve LeeRichard HynsonBrent RubySteven Gaskill
    • Steve LeeRichard HynsonBrent RubySteven Gaskill
    • A61K31/198C08B20060101
    • A61K36/48
    • A composition of bio-active compounds and methods for facilitating and supporting the metabolism and transport of glucose and carbohydrates into muscle cells, promoting muscle function and growth, promoting glycogen synthesis, enhancing glucose disposal, stimulating pancreatic beta cells, promoting metabolic recovery, promoting muscle recovery, promoting lean body mass, and promoting fat burning. Preferably, the composition of bio-active compounds includes a combination of 4-hydroxyisoleucine with at least one amino acid selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, lysine, histidine, gamma-amino butyrate and tyrosine. In one presently preferred embodiment of the present invention, the combination is derived, isolated, and/or extracted from fenugreek seeds. Methods for using a novel composition of bio-active compounds from fenugreek seed for facilitating and supporting the metabolism and transport of glucose and carbohydrates into muscle cells, promoting muscle function and growth, promoting glycogen synthesis, enhancing glucose disposal, stimulating pancreatic beta cells, promoting metabolic recovery, promoting muscle recovery, promoting lean body mass, and promoting fat burning are also disclosed, wherein methods comprise the steps of: (1) providing an effective amount of a composition of bio-active compounds derived, isolated, and/or extracted from fenugreek seeds; and (2) administering the composition to a human or animal.
    • 生物活性化合物的组合物和促进和支持葡萄糖和碳水化合物进入肌细胞的代谢和转运,促进肌肉功能和生长,促进糖原合成,增强葡萄糖处置,刺激胰腺β细胞,促进代谢恢复,促进肌肉的方法 恢复,促进瘦体重,促进脂肪燃烧。 优选地,生物活性化合物的组合物包括4-羟基异亮氨酸与至少一种选自精氨酸,天冬氨酸,苏氨酸,丝氨酸,谷氨酸,脯氨酸,甘氨酸,丙氨酸,半胱氨酸,缬氨酸,甲硫氨酸, 异亮氨酸,亮氨酸,色氨酸,苯丙氨酸,鸟氨酸,赖氨酸,组氨酸,γ-氨基丁酸和酪氨酸。 在本发明的一个目前优选的实施方案中,从葫芦巴种子中衍生,分离和/或提取该组合。 使用来自葫芦巴种子的生物活性化合物的新组合物的方法,用于促进和支持葡萄糖和碳水化合物向肌肉细胞的代谢和转运,促进肌肉功能和生长,促进糖原合成,增强葡萄糖处置,刺激胰腺β细胞,促进 还公开了代谢恢复,促进肌肉恢复,促进瘦体重和促进脂肪燃烧,其中方法包括以下步骤:(1)提供有效量的衍生,分离和/或提取的生物活性化合物的组合物 来自葫芦巴种子; 和(2)将组合物给予人或动物。