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1. 发明公开

CN88102468A N-酰苯胺除草剂失效
公开(公告)号：CN88102468A
公开(公告)日：1988-11-16
申请号：CN88102468
申请日：1988-04-29
申请人：国际壳牌研究有限公司
发明人：戴维德·穆勒
IPC分类号： C07C103/178 , C07D213/64 , A01N37/18 , A01N43/40
CPC分类号： C07D213/64 , A01N39/02 , A01N43/40
摘要：含有式I化合物的新型除草剂及其配方、应用和制备。其中R1代表卤原子、烷基、卤烷氧基、卤烷基或烷氧羰基；R2代表氢或卤原子；R3至R6各自代表氢、卤原子、氰基、烷基、卤烷基、烷氧基或卤烷氧基；R7代表氢、卤原子、烷基、卤烷氧基、卤烷基或烷氧羰基；A代表氮原子或-CH-。

2. 发明专利

JPS5644062B1 失效
公开(公告)号：JPS5644062B1
公开(公告)日：1981-10-16
申请号：JP3664071
申请日：1971-05-27
IPC分类号： C07C235/06 , C07C51/363 , C07C51/367 , C07C51/377 , C07C59/70 , C07D263/06 , C07D303/24 , C07D319/20 , C07C103/178 , C07C102/00 , C07C103/34 , C07C103/38 , C07C149/36 , C07D295/18
摘要： Cpds (I) their salts esters and aldehyde condensation products where R' is H, alkyl(opt. substd by OH, aryl or aryloxy) cycloalkyl or alkenyl, R2 is H and R3 is H, alkyl hydroxy alkyl, cycloalkyl, alkoxy alkyl, alkenyl or aralkyl or NR2R3 is a heterocyclic radical; R4 is H, halogen alkyl, alkenyl, OH, alkylthio, alkoxy, alkenyloxy, aralkoxy, or haloalkyl; R5 is H or alkyl and A is alkylene are prepd by standard methods for forming basic hydroxy ethers or by methods where the ether gp R2R3NCO-A-O- is formed. Medicaments may be in forms for oral or parenteral administration or may be aerosols and may opt. contain other drugs e.g. sedatives vasodilators, duiretics, hypotensives, hypocardiac depressants anti-parkinsonism agents cardiotonics and bronchodilators.

4. 发明专利

JPS5020056B1 失效
公开(公告)号：JPS5020056B1
公开(公告)日：1975-07-11
申请号：JP3486771
申请日：1971-05-22
IPC分类号： A61K31/16 , A61K31/44 , A61K31/495 , A61K31/535 , C07D213/00 , C07D241/00 , C07D279/00 , C07D295/00 , C07C103/178

5. 发明授权

US4143069A N-(1,1 Substituted propynyl)-.alpha.-(3,5-substituted phenoxy) alkyl amides 失效
标题翻译： N-（1,1-取代的丙基） - “ - （3,5-取代的苯氧基）烷基酰胺
公开(公告)号：US4143069A
公开(公告)日：1979-03-06
申请号：US782218
申请日：1977-03-28
申请人： Duane R. Arneklev , Don R. Baker , Francis H. Walker
发明人： Duane R. Arneklev , Don R. Baker , Francis H. Walker
IPC分类号： A01N39/02 , C07C103/178
CPC分类号： A01N39/02
摘要： N-(1,1 substituted propynyl)-.alpha.-(3,5-substituted phenoxy) alkyl amides compounds having the formula ##STR1## in which R.sup.1 and R.sup.2 are independently halogen or alkyl having 1 to 4 carbon atoms; R.sup.3 is alkyl having 1 to 4 carbon atoms; R.sup.4 and R.sup.5 are independently hydrogen or alkyl having 1 to 3 carbon atoms; and their use as herbicides.

6. 发明授权

US4617154A Chemical process involving ethers and amines 失效
标题翻译：涉及醚和胺的化学过程
公开(公告)号：US4617154A
公开(公告)日：1986-10-14
申请号：US647235
申请日：1984-09-04
申请人： Michael J. Green
发明人： Michael J. Green
IPC分类号： C07C49/175 , B01J31/00 , C07B31/00 , C07B41/04 , C07B43/04 , C07C45/00 , C07C45/71 , C07C67/00 , C07C69/708 , C07C227/00 , C07C227/06 , C07C229/12 , C07C253/00 , C07C255/13 , C07C121/38 , C07C103/175 , C07C103/178
CPC分类号： C07C255/00 , C07C253/00 , C07C253/30 , C07C45/71 , Y02P20/52
摘要： A process for the production of (1) an ether or (2) a second amine comprises reacting an activated olefin with respectively an alcohol or first amine in the presence of a catalyst which is either (a) an amidine or (b) a Lewis base and epoxide. The same catalyst may also be used to carry out the reverse reaction in which an activated olefin and an alcohol or first amine are produced from the appropriate ether or second amine.
摘要翻译：制备（1）醚或（2）第二胺的方法包括在催化剂存在下使活化的烯烃与醇或第一胺反应，催化剂为（a）脒或（b）路易斯酸碱和环氧化物。也可以使用相同的催化剂进行反应，其中由适当的醚或第二胺产生活化的烯烃和醇或第一胺。

7. 发明授权

US4243410A Herbicidally active .alpha.-(4-phenoxyphenoxy)propionic acid alkoxyalkyl amides, herbicidal compositions containing them and their use 失效
标题翻译：除草活性α-（4-苯氧基苯氧基）丙酸烷氧基烷基酰胺，含有它们的除草组合物及其用途
公开(公告)号：US4243410A
公开(公告)日：1981-01-06
申请号：US1515
申请日：1979-01-08
申请人： Beat Bohner , Otto Rohr
发明人： Beat Bohner , Otto Rohr
IPC分类号： A01N39/02 , C07C67/00 , C07C231/00 , C07C231/02 , C07C231/12 , C07C235/20 , A01N37/18 , C07C103/178
CPC分类号： A01N39/02
摘要： The present invention relates to novel herbicidally active 4-(p-trifluoromethylphenoxy)-.alpha.-phenoxypropionic acid alkoxyalkyl amides, processes for their manufacture and also herbicidal compositions which contain them. The preferred utility of the novel compounds is the selective control of monocotyledonous weeds.The novel compounds have the general formula I ##STR1## wherein "alkylene" represents a straight or branched saturated hydrocarbon chain of 1 to 4 carbon atoms and R represents an alkyl radical of 1 to 4 carbon atoms.The novel compounds are obtained by reacting a halide or lower alkyl ester of 4-(p-trifluoromethylphenoxy)-.alpha.-phenoxypropionic acid with an alkoxyalkyl amineH.sub.2 N-alkylene-O-Ror by reacting a hydroxydiphenyl ether ##STR2## wherein Y is hydrogen or a cation, with an .alpha.-halopropionic acid alkoxyalkyl amide of the formula ##STR3## in the presence of an acid acceptor. Preferred compounds of the formula I are an N-(2-methoxy)-ethylamide and N-(3-methoxy)-propyl-(2)-amide.
摘要翻译：本发明涉及新颖的除草活性4-（对三氟甲基苯氧基）-α-苯氧基丙酸烷氧基烷基酰胺，其制备方法以及含有它们的除草组合物。新化合物的优选用途是单子叶杂草的选择性控制。新化合物具有通式I（I），其中“亚烷基”表示1至4个碳原子的直链或支链饱和烃链，R表示1至4个碳原子的烷基。通过使4-（对三氟甲基苯氧基）-α-苯氧基丙酸的卤代物或低级烷基酯与烷氧基烷基胺H 2 N-亚烷基-OR反应或通过羟基二苯基醚（IMAGE）与Y是氢或阳离子，在酸受体的存在下与式“IMAGE”的α-卤代丙酸烷氧基烷基酰胺反应。优选的式I化合物是N-（2-甲氧基） - 乙基酰胺和N-（3-甲氧基） - 丙基 - （2） - 酰胺。

8. 发明授权

US4051184A N-(1,1 substituted propynyl)-.alpha.(3,5-substituted phenoxy) alkyl amides and their use as herbicides 失效
标题翻译： N-（1,1取代的丙炔） - （3,5-取代的苯氧基）亚胺酰胺及其作为除草剂的用途
公开(公告)号：US4051184A
公开(公告)日：1977-09-27
申请号：US617454
申请日：1975-09-29
申请人： Duane R. Arneklev , Don R. Baker , Francis H. Walker
发明人： Duane R. Arneklev , Don R. Baker , Francis H. Walker
IPC分类号： A01N39/02 , C07C59/68 , C07C103/178
CPC分类号： C07C59/68 , A01N39/02
摘要： N-(1,1 substituted propynyl)-.alpha.(3,5-substituted phenoxy) alkyl amides compounds having the formula ##STR1## in which R.sup.1 and R.sup.2 are independently halogen or alkyl having 1 to 4 carbon atoms; R.sup.3 is alkyl having 1 to 4 carbon atoms; R.sup.4 and R.sup.5 are independently hydrogen or alkyl having 1 to 3 carbon atoms; and their use as herbicides.

9. 发明授权

EP0099707B1 2-Aminoethyl ether derivatives, processes for their preparation and pharmaceutical compositions containing them 失效
标题翻译： 2-氨基乙醚衍生物，其制备方法和含有它们的药物组合物
公开(公告)号：EP0099707B1
公开(公告)日：1986-12-10
申请号：EP83303983.7
申请日：1983-07-08
申请人： BEECHAM GROUP PLC
发明人： Cantello, Barrie Christian Charles
IPC分类号： C07C93/04 , C07C93/10 , C07C93/14 , C07C103/34 , C07C103/178 , C07C101/42 , C07C101/16 , C07C149/42 , A61K31/16
CPC分类号： C07C255/00 , C07C43/225 , C07C43/303 , C07C43/313 , C07C229/38 , C07D307/81

10. 发明公开

EP0139921A1 2-phenylethylamine derivatives 失效
标题翻译： 2-苯基乙胺衍生物。
公开(公告)号：EP0139921A1
公开(公告)日：1985-05-08
申请号：EP84109391.7
申请日：1984-08-08
申请人： BEECHAM GROUP PLC
发明人： Hindley, Richard Mark , Berge, John
IPC分类号： C07C93/14 , C07C101/42 , C07C103/178 , C07C103/34 , C07D307/81 , A61K31/135 , A61K31/16 , A61K31/19 , A61K31/215 , A61K31/34
CPC分类号： C07C255/00 , C07C229/38 , C07D307/81 , C07D317/12 , C07D317/16
摘要： Compounds of formula (I):
or a pharmaceutically acceptable salt, ester or amide thereof, wherein:

Ar is benzofuran-2-yl, or phenyl optionally substituted by groups R' and/or R 2 wherein R' is halogen, trifluoromethyl or hydroxy and R 2 is halogen;
R 3 is hvdrogen or methyl;
Xis-
in which
a is an integer from 1 to 6,
b is an integer from 2 to 7,
M is hydroxy, C 1-6 alkoxy, phenyl C 1-6 alkoxy, or-NR 4 R 5 in which R 4 and R 5 are each hydrogen or C 1-6 alkyl or together form a five or six membered heterocyclic ring;
Y is C 2-6 straight or branched alkylene, with at least two carbon atoms between the -O- and -OH; and n is 1 or 2, having anti-obesity and/or anti-hyperglycaemic activity, pro- cessesfortheir preparation and their pharmaceutical use.

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