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1. 发明授权

US06565789B2 Methods for producing low binding surfaces 有权
标题翻译：生产低粘结表面的方法
公开(公告)号：US06565789B2
公开(公告)日：2003-05-20
申请号：US09507421
申请日：2000-02-18
申请人： Dana Craig Bookbinder , Edward John Fewkes, Jr. , James Arthur Griffin , Frances M. Smith , David L. Tennent
发明人： Dana Craig Bookbinder , Edward John Fewkes, Jr. , James Arthur Griffin , Frances M. Smith , David L. Tennent
IPC分类号： B28B722
CPC分类号： C07H21/00 , B01L3/50 , B01L3/5082 , B01L2200/12 , B01L2300/16 , B05D7/02 , C07B2200/11 , C08J7/047 , C08J7/065 , C08J2471/00 , C09D5/00 , G01N33/54393
摘要： Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions. Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.
摘要翻译：蛋白质结合水平小于约50-80ng / cm 2的疏水性聚合物表面通过以下方式实现：（1）将由溶剂和HLB数小于5的非离子表面活性剂组成的涂布溶液施加到表面 ; 和（2）干燥表面以除去溶剂，从而使表面活性剂与疏水性聚合物直接接触。已经发现低HLB值和干燥步骤的组合产生低结合表面，其可以经受多次用水和/或蛋白质溶液洗涤。或者，低结合表面可以通过将非离子表面活性剂施加到与熔融聚合物接触的模具表面并将聚合物形成所需形状，例如多孔板，移液管尖端等来制备。此外，低粘合表面可以通过将HLB数小于或等于10的非可溶性非离子表面活性剂在模制制品之前加入到聚合物共混物中来制备。

2. 发明授权

US06500376B1 Multiple injection compression molding process 有权
标题翻译：多次注射压缩成型工艺
公开(公告)号：US06500376B1
公开(公告)日：2002-12-31
申请号：US09492413
申请日：2000-01-27
申请人： Craig William Pack , Ronald Dennis Polley
发明人： Craig William Pack , Ronald Dennis Polley
IPC分类号： B28B722
CPC分类号： B29C45/1635 , B29C45/561 , B29C2045/565
摘要： A method of injection molding a layered plastic component includes providing a sealing structure around the periphery of a mold cavity formed between first and second mold halves to contain plastic material in the cavity during injection. The first and second mold halves are closed to a first gap therebetween. A first plastic material is injected into the cavity. The first and second mold halves are closed together to a full closure position to compress the first plastic material. The first and second mold halves are held together for a period of time sufficient to partially solidify the first plastic material. The first and second mold halves are opened to a second gap therebetween, and at least one stop member is moved into position between the first and second mold halves. A second plastic material is injected into the mold cavity, and the first and second halves are closed together against said stop member, and the mold halves are maintained in this position for solidification of the second plastic material to form the layered plastic component.
摘要翻译：注塑成型分层塑料部件的方法包括在形成于第一和第二半模之间的模腔的周边周围提供密封结构，以在注射期间将塑性材料容纳在腔体中。第一和第二半模封闭到它们之间的第一间隙。将第一塑料材料注入空腔。第一和第二半模封闭在一起，以完全封闭位置以压缩第一塑料材料。将第一和第二半模保持在一起足以部分固化第一塑料材料的时间。第一和第二半模被打开到其间的第二间隙，并且至少一个止动构件移动到第一和第二半模之间的位置。将第二塑料材料注入到模具腔中，并且将第一和第二半部分相对于所述止动构件封闭，并且将半模保持在该位置以固化第二塑料材料以形成层状塑料部件。

3. 发明授权

US06296797B1 Method for producing composite bodies 有权
标题翻译：复合体的制造方法
公开(公告)号：US06296797B1
公开(公告)日：2001-10-02
申请号：US09509599
申请日：2000-05-22
申请人： Ursula Ziegler , Klaus Kurz , Frank Reil
发明人： Ursula Ziegler , Klaus Kurz , Frank Reil
IPC分类号： B28B722
CPC分类号： B29C45/1676 , B29K2059/00 , B60R13/04
摘要： Process for producing a composite article from a polyacetal (component a) with directly molded-on functional elements made from one or more thermoplastic elastomers (component b), and wherein components a and b have differing hardness, and the material with the greater hardness (component a) is initially premolded in a first step in a mold, and then is either cooled and removed from the mold and then placed into another, larger cavity, or is partially removed from the mold, but remains in a portion of the mold, and is then moved to a larger cavity, or, without removal from the mold, remains in the same mold, which is enlarged by means of a movable device, and in a second step, by overmolding with the material with the lesser hardness (component b), the molding formed from component a is firmly bonded to this material and is then removed from the mold as a composite article.
摘要翻译：由聚缩醛（组分a）和由一种或多种热塑性弹性体（组分b）制成的直接成型的功能元件制备复合制品的方法，其中组分a和b具有不同的硬度，以及硬度较高的材料组件a）最初在模具中的第一步骤中预成型，然后被冷却并从模具中取出，然后被放置到另一个更大的空腔中，或者部分地从模具中移除，但是保留在模具的一部分中，然后移动到更大的空腔，或者不从模具中取出，保持在相同的模具中，该模具通过可移动装置而被扩大，并且在第二步骤中，通过用较低硬度的材料（部件 b），由组分a形成的模制品牢固地粘合到该材料上，然后作为复合制品从模具中取出。

4. 发明授权

US06274075B1 Five layer injection molding apparatus having four position valve member actuating mechanism 有权
标题翻译：具有四位置阀构件致动机构的五层注塑设备
公开(公告)号：US06274075B1
公开(公告)日：2001-08-14
申请号：US09327641
申请日：1999-06-08
申请人： Jobst Ulrich Gellert , Denis L. Babin
发明人： Jobst Ulrich Gellert , Denis L. Babin
IPC分类号： B28B722
CPC分类号： B29C45/1607 , B29C2045/1612 , B29C2045/1648 , B29C2045/273 , B29C2045/2872 , B29K2105/253
摘要： Valve gated multi-cavity injection molding apparatus for five layer molding having actuating mechanisms for reciprocating elongated valve members between four different positions. Each actuating mechanism has a front and a rear aligned cylinders, a first piston connected to the head of one of the valve members in the front cylinder and second and third pistons in the rear cylinder. The third piston has a stem portion which extends forwardly through the second piston into the front cylinder. Hydraulic pressure from four hydraulic lines connected to each actuating mechanism reciprocates each elongated valve member between the different positions. In the first closed position, the front end of the valve member is seated in the gate. In the second position, the front end of the valve member is retracted sufficiently to allow an initial amount of PET to flow from an outer annular melt channel through the gate. Then the valve member is retracted further to a third position to allow simultaneous flow of the PET and a barrier material from an inner annular melt channel. Then the valve member is retracted to a fully open position which allows the simultaneous flow of PET from a central melt channel. When the cavity is almost filled, the valve member returns briefly to the second position for filling before returning to the closed position for ejection.
摘要翻译：用于五层模制的阀门浇口多腔注射成型装置，其具有用于在四个不同位置之间的往复式细长阀构件的致动机构。每个致动机构具有前和后对齐的气缸，第一活塞连接到前气缸中的一个阀构件的头部以及后气缸中的第二和第三活塞。第三活塞具有杆部，其向前延伸穿过第二活塞进入前缸。连接到每个致动机构的四个液压管路的液压压力使每个细长阀构件在不同位置之间往复运动。在第一关闭位置，阀构件的前端位于门中。在第二位置，阀构件的前端充分缩回以允许初始量的PET从外部环形熔体通道流过门。然后，阀构件进一步缩回到第三位置，以允许PET和阻挡材料从内部环形熔体通道同时流动。然后，阀构件缩回到完全打开的位置，其允许从中心熔体通道同时流动PET。当空腔几乎被填充时，阀构件在返回到关闭位置之前短暂返回到第二位置以进行填充。

5. 发明授权

US06251323B1 Plastic molding process and products produced thereby 失效
标题翻译：塑胶成型工艺及产品生产
公开(公告)号：US06251323B1
公开(公告)日：2001-06-26
申请号：US09367046
申请日：1999-08-06
申请人： Herbert K. Hoedl , Eufredo Maury , Dave Cockle
发明人： Herbert K. Hoedl , Eufredo Maury , Dave Cockle
IPC分类号： B28B722
CPC分类号： B29C43/146 , B29C43/18 , B29C70/70 , B29L2031/7178
摘要： The invention utilizes the adhesive properties which plastic material exhibits while still hot combined with a multi stage molding operation wherein one side of an insert or core located in one side of a mold is coated with molten plastic on a first closing of the mold, the mold is then opened with the plastic still hot to remove the insert or core from the one mold side by virtue of its adherence by the hot plastic to the other mold side, a second charge of plastic is then introduced into the said one mold side and the mold is closed again with the plastic in a molten state to complete the encapsulation of the insert or core.
摘要翻译：本发明利用塑料材料表现出的粘合性能，同时热结合多级成型操作，其中位于模具一侧的插入件或芯的一侧在模具的第一次闭合上涂覆有熔融塑料，模具然后用塑料仍然热打开，由于其通过热塑料粘附到另一个模具侧而从一个模具侧移除插入件或芯，然后将第二次塑料充入到所述一个模具侧，并且模具再次用塑料在熔融状态下关闭，以完成插入件或芯的封装。

6. 发明授权

US06187242B1 Connector molding method 有权
标题翻译：连接器成型方法
公开(公告)号：US06187242B1
公开(公告)日：2001-02-13
申请号：US09146242
申请日：1998-09-03
申请人： Katsuhiko Onoda
发明人： Katsuhiko Onoda
IPC分类号： B28B722
CPC分类号： F02M51/005 , B29C45/14639 , B29C45/1671 , B29L2031/3481 , F02M2037/082 , H01R43/24
摘要： A connector molding method in which the accuracy of positioning of a plurality of metal terminals is enhanced, and also even if part of a housing is formed into a thickened portion, a shrink mark and a warp will not develop in the molded connector. At a first stage of the connector molding method of the invention, a plurality of male metal terminals are kept insulated from one another, and in this condition these metal terminals are insert molded, thereby forming a primary molded body. Then, at a second stage, the primary molded body is properly positioned, and is insert molded, thereby forming a secondary molded body which is a final molded product (connector). In order to prevent the development of a shrink mark and a warp due to the formation of a thickened portion of the connector, a core portion of the thickened portion is formed at the time of molding the primary molded body, and a shell portion of the thickened portion, having a generally uniform thickness of 1 mm to 2 mm, is formed at the time of molding the secondary molded body. The core portion of the primary molded body is utilized for the positioning for the second molding, and therefore the male metal terminals can be positioned highly precisely.
摘要翻译：一种连接器成型方法，其中多个金属端子的定位精度提高，并且即使壳体的一部分形成为加厚部分，也不会在模制连接器中产生收缩痕迹和翘曲。在本发明的连接器成型方法的第一阶段，多个公金属端子彼此保持绝缘，在这种情况下，这些金属端子被嵌入成型，从而形成一次成型体。然后，在第二阶段，将一次成型体适当定位，并嵌入成型，从而形成作为最终成型品（连接器）的二次成型体。为了防止由于连接器的增厚部分的形成引起的收缩痕迹和翘曲的发展，在成型一次成型体时形成增厚部的芯部，并且在二次成型体成型时形成具有1mm〜2mm的大致均匀厚度的增厚部。一次成型体的芯部用于第二成型的定位，因此可以高精度地定位公金属端子。

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