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    • 1. 发明授权
    • Crystallization media
    • 结晶介质
    • US06267935B1
    • 2001-07-31
    • US09344007
    • 1999-06-25
    • Wim G. J. HolSteven H. SarfatyLansing J. StewartHidong Kim
    • Wim G. J. HolSteven H. SarfatyLansing J. StewartHidong Kim
    • B09D900
    • B01L3/06B01L3/5085C30B7/00C30B29/58
    • In one aspect, the present invention provides crystallization solutions useful for crystallizing proteins and other molecules, especially macromolecules. In a presently preferred embodiment, the crystallization solutions of the invention are combined as four crystallization solution sets. Each of the four crystallization solution sets includes forty eight different crystallization solutions. Each individual crystallization solution includes a precipitant and a buffer, and optionally includes at least one additive. In another aspect, the present invention provides kits including a plurality of crystallization solutions of the present invention and at least one crystallization plate that preferably includes a plurality of reservoirs. Preferably the crystallization solutions are disposed within the reservoirs of the crystallization plates.
    • 一方面,本发明提供了用于结晶蛋白质和其它分子,特别是大分子的结晶溶液。 在目前优选的实施方案中,将本发明的结晶溶液组合为四个结晶溶液组。 四个结晶溶液组中的每一个包括四十八种不同的结晶溶液。 每个单独的结晶溶液包括沉淀剂和缓冲剂,并且任选地包括至少一种添加剂。 在另一方面,本发明提供了包括本发明的多种结晶溶液和至少一种优选包括多个储存器的结晶板的试剂盒。 优选地,结晶溶液设置在结晶板的储存器内。