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1. 发明申请

WO2022010722A1 METHODS AND SYSTEMS FOR DETERMINING COLLATERAL VENTILATION 审中-公开
公开(公告)号：WO2022010722A1
公开(公告)日：2022-01-13
申请号：PCT/US2021/040000
申请日：2021-06-30
申请人： PULMONX CORPORATION
发明人： RADHAKRISHNAN, Sri , OLIVERA, Ryan
IPC分类号： A61B5/08 , A61B1/267 , A61B5/083 , A61B5/085 , A61B5/087 , A61B5/097 , A61B5/091 , A61B5/4836 , A61B5/6853 , A61B5/742
摘要： Methods and systems for determining collateral ventilation are disclosed. Methods may comprise introducing a diagnostic catheter into a lung compartment via an assisted ventilation device, inflating the occluding member to isolate the lung compartment, and performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device. The diagnostic procedure comprises determining an exhaled volume from the isolated lung compartment over a predetermined period of time while the patient is ventilated via the assisted ventilation device. The presence collateral ventilation may be determined based on the exhaled volume from the isolated lung compartment over the predetermined period of time.

2. 发明申请

WO2022170263A2 FLOW-DIRECTED DEVICES FOR MEASURING PHYSIOLOGICAL DATA IN RIGHT HEART, AND METHODS AND SYSTEMS THEREOF 审中-公开
公开(公告)号：WO2022170263A2
公开(公告)日：2022-08-11
申请号：PCT/US2022/015666
申请日：2022-02-08
申请人： FANNIN PARTNERS, LLC (D/B/A FANNIN INNOVATION STUDIO)
发明人： DELGADO, Reynolds M., III , JAFARI, Niloufar , LUK, Christine , GIBBENS, Amanda , HEFFERNAN, Michael J. , LINBECK, Leo, III , CHATTERJEE, Dev , VARADHACHARY, Atul
IPC分类号： A61B5/0215 , A61B5/00 , A61B5/6853 , A61B5/6859
摘要： An apparatus includes an elongate body including a proximal portion and a distal portion. The elongate body defining a lumen. A set of sensors are disposed on the distal portion of the elongate body. An electrical connector may be coupled to the proximal portion of the elongate body, and is coupled to the set of sensors via an electrical wire extending through the elongate body. A guide member is disposed on the distal portion near the set of sensors, the guide member transitionable between an undeployed configuration and a deployed configuration. The guide member in the deployed configuration is configured to guide movement of the distal portion of the elongate body through a vascular system of a subject using blood flow. The elongate body may have a diameter less than or equal to 8 millimeters (mm).

3. 发明申请

WO2022010720A1 SYSTEMS AND METHODS FOR ENDOBRONCHIAL DIAGNOSTICS 审中-公开
公开(公告)号：WO2022010720A1
公开(公告)日：2022-01-13
申请号：PCT/US2021/039991
申请日：2021-06-30
申请人： PULMONX CORPORATION
发明人： RADHAKRISHNAN, Sri , OLIVERA, Ryan
IPC分类号： A61B5/08 , A61B1/267 , A61B5/083 , A61B5/085 , A61B5/087 , A61B5/097 , A61B5/082 , A61B5/0876 , A61B5/6853 , A61M16/208
摘要： Methods and systems for accessing and diagnosing diseased lung compartments are disclosed. Methods may comprise introducing a diagnostic catheter with an occluding member at its distal end into a lung segment; inflating the occluding member to isolate the lung compartment; and performing a diagnostic procedure with the catheter. The proximal end of the diagnostic catheter is configured to be attached to a console. Methods may also include allowing air to enter the lung compartment through the passage in the catheter while the patient is inhaling and blocking air from being expelled from the lung compartment through the catheter passage while the patient is exhaling by using a one-way flow element adapted to be disposed within or in-line with the passage of the catheter so that flow in a proximal-to-distal direction is allowed and flow in a distal-to-proximal direction is inhibited or prevented.

4. 发明申请

WO2021229552A1 VORRICHTUNG UND VERFAHREN ZUR WECHSELWEISEN MESSUNG THORAKALER DRUCKE UND ZUR ÖSOPHAGEALEN SEKRET-DICHTUNG 审中-公开
公开(公告)号：WO2021229552A1
公开(公告)日：2021-11-18
申请号：PCT/IB2021/054222
申请日：2021-05-17
申请人： CREATIVE BALLOONS GMBH
发明人： GÖBEL, Fred
IPC分类号： A61B5/00 , A61B5/08 , A61B2505/03 , A61B2562/0247 , A61B5/0803 , A61B5/296 , A61B5/6853 , A61B5/6885 , A61B5/7246 , A61B5/7282 , A61B5/742 , A61B5/7475
摘要： Die vorliegende Erfindung beschreibt eine Vorrichtung und ein Verfahren zur wechselweisen Messung des thorakalen bzw. pleuralen Drucks und zur gastropharyngealen oder trachealen Dichtung, wobei die.Ballonkomponente eines tracheal oder ösophageal platzierten Tubus bzw. Katheters zwischen zwei Füll- bzw. Funktionszusfänden wechselt, wobei der Fülizustand der Ballorikomponente im messenden Modus eine schlaffe, im Verlauf der Messung einen volumenkonstanten, voiumendefinierten Wert annimmt, und der Füllzustand des Ballons im ösophageal oder tracheal dichtenden Funkfionsmodus einen vom Anwender vorgegeben, konstanten, dichtenden Druck aufrechterhält. Die mit der Tubus- oder Kathetereinheit verbundene Reglervorrlchtung gewährleistet im Zustand der trachealen oder ösophagealen Dichtung eine rasche Verschiebung von Füllmedium in und aus dem Tubus- oder Katheterballon, wobei der tracheal oder ösophageal dichtende Zieldruck kontinuierlich aufrechterhalten wird, indem atemmechanisch bedingte Druckschwankungen im Ballon durch eine fortlaufende, kompensierende Verschiebung von Füllvolumen kompensiert werden. Dabei kann der Anwender zwischen den beiden Funktionszuständen durch eine manuelle Umschaltfunktion oder durch einen programmierbaren, zeitlichen Zyklus wechseln. Neben der Möglichkeit eines intermittierenden, atemmechanischen Monitorings und einer kontinuierlich, tracheal oder ösophageal dichtenden Ballontamponade ermöglicht der tracheal oder ösophageal platzierte Ballon in beiden Funktionszuständen die thorakale Ableitung eines triggernden, atemmechanischen Signals, welches in einem mit der Vorrichtung konnektierten Beatmungsgerät einen, den Patienten assistierenden Beatmungshub auslösen kann. Die Erfindung beschreibt ferner bauliche und funktionelle Optionen für die zeitgleiche Ableitung eines neuronalen und/oder muskulären elektrischen Signals vom Zwerchfell (Diaphragma) des Patienten und eines atemmechanischen Signals auf der Grundlage tracheal oder ösophageal abgeleiteter, thorakaler bzw. pleuraler Druckschwankungen.

5. 发明申请

WO2021188602A2 BLOOD FLOW CONTROL DEVICES, SYSTEMS, AND METHODS AND ERROR DETECTION THEREOF 审中-公开
公开(公告)号：WO2021188602A2
公开(公告)日：2021-09-23
申请号：PCT/US2021/022644
申请日：2021-03-16
申请人： CERTUS CRITICAL CARE, INC. , WAKE FOREST UNIVERSITY HEALTH SCIENCES
发明人： JOHNSON, Michael Austin , POISNER, David , MCWADE, Melanie , WILLIAMS, Timothy , NEFF, Lucas
IPC分类号： A61M60/139 , A61M60/295 , A61M60/31 , A61M60/497 , A61M60/531 , A61M60/538 , A61M60/585 , A61B17/12 , A61B17/00 , A61B17/12036 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B2017/00022 , A61B2017/00075 , A61B2017/00119 , A61B2017/00398 , A61B2017/00557 , A61B2017/00725 , A61B2017/00734 , A61B2090/064 , A61B2090/0809 , A61B2560/0257 , A61B2560/0276 , A61B34/20 , A61B34/25 , A61B5/02158 , A61B5/4836 , A61B5/6853 , A61B5/746
摘要： Systems and methods for blood flow control are described herein. In some variations, a blood flow control system may comprise a blood flow control device. The blood flow control device may be placed within a body of a patient and may comprise an expandable member and a sensor. The sensor may be configured to measure at least one of a physiologic condition of the patient and a pressure associated with the expandable member. The blood flow control system may include at least one controller communicably coupled to the sensor to: receive data indicative of at least one of the physiologic condition of the patient and the pressure associated with the expandable member from the sensor, compare the received data with target data, identify at least one error based on the comparison, and in response to identifying the error, inhibit at least one function of the blood flow control system.

6. 发明申请

WO2021170694A2 SYSTEM ZUM DURCHFÜHREN EINER ANGIOPLASTIE UND VERFAHREN ZUM BESTIMMEN EINES DURCHMESSERS EINES BALLONS EINES BALLONKATHETERS 审中-公开
公开(公告)号：WO2021170694A2
公开(公告)日：2021-09-02
申请号：PCT/EP2021/054629
申请日：2021-02-25
申请人： BIOTRONIK AG
发明人： WESSELMANN, Matthias , HUESEYIN, Yilmaz , QUINT, Bodo , FARGAHI, Amir
IPC分类号： A61B5/107 , A61B5/00 , A61M25/10 , A61B5/1076 , A61B5/6853 , A61M2025/0166 , A61M25/10184
摘要： Ein System zum Durchführen einer Angioplastie umfasst einen Ballonkatheter (1), der einen mit einem elektrisch leitfähigen Fluid befüllbaren Ballon (10) und zwei in dem Ballon (10) angeordnete Elektroden (12, 13) aufweist, und eine elektrisch mit den Elektroden (12, 13) verbundene Auswerteeinheit (14). Die Auswerteeinheit (14) ist hierbei dazu ausgebildet, zumindest ein Anregungssignal (U) an die Elektroden (12, 13) anzulegen und zumindest ein Messsignal (I) über die Elektroden (12, 13) zu messen, um anhand des zumindest einen Messsignals (I) Impedanzwerte (Z1, Z2) bei unterschiedlichen Frequenzen zu ermitteln und einen mit dem elektrischen Widerstand des Fluids in dem Ballon (10) korrelierten Kennwert zu bestimmen.

7. 发明申请

WO2022271416A1 MEDICAL LEAD SYSTEM 审中-公开
公开(公告)号：WO2022271416A1
公开(公告)日：2022-12-29
申请号：PCT/US2022/031532
申请日：2022-05-31
申请人： MEDTRONIC, INC.
发明人： SEIFERT, Kevin R. , WHITMAN, Teresa A. , BAXTER, Jonathan E. , MARSHALL, Mark T. , HUGHES, Jonathan A.
IPC分类号： A61B8/12 , A61B17/34 , A61M25/06 , A61B2505/05 , A61B5/251 , A61B5/283 , A61B5/6853 , A61N1/0573
摘要： A medical lead system including an elongated lead body configured to extend through vasculature of a patient. The lead body mechanically supports a fixation member extending distal to a distal end of the lead body. A balloon is affixed to a distal portion of the lead body. The balloon is configured to inflate to extend distal to the distal end of the lead body. The fixation member is configured to extend within a distal cavity defined by the inflated balloon. The medical lead system is configured such that an electrode mechanically supported by the fixation member may electrically communicate with tissue of the patient when the balloon is in the inflated configuration.

8. 发明申请

WO2021144248A1 IMPLANTABLE PRESSURE SENSOR PROBE AND CATHETER FOR IMPLANTING A PRESSURE SENSOR PROBE 审中-公开
公开(公告)号：WO2021144248A1
公开(公告)日：2021-07-22
申请号：PCT/EP2021/050459
申请日：2021-01-12
申请人： BIOTRONIK SE & CO. KG
发明人： ARNDT, Andreas , NOLLERT, Georg
IPC分类号： A61B5/0215 , A61B5/00 , A61B5/06 , A61N1/05 , A61N1/39 , A61N1/365 , A61M25/00 , A61B2560/066 , A61B2562/0247 , A61B5/064 , A61B5/4836 , A61B5/6839 , A61B5/6853 , A61B5/6869 , A61M2025/0002 , A61M2025/0163 , A61M2205/04 , A61M2210/125 , A61M25/0125 , A61M25/0662 , A61N1/36564 , A61N1/3925
摘要： The disclosure relates to an implantable pressure sensor probe (1) for measuring a pressure in the left atrium (LA) of a human heart, wherein a distal portion of the pressure sensor probe (1) has a pressure sensor (12) for detecting the pressure. A catheter is also described.

9. 发明申请

WO2021133611A1 CATHETER INSERT INCLUDING ONE OR MORE SENSORS 审中-公开
公开(公告)号：WO2021133611A1
公开(公告)日：2021-07-01
申请号：PCT/US2020/065365
申请日：2020-12-16
申请人： COVIDIEN LP
发明人： MILLER, David J.
IPC分类号： A61B5/20 , A61B5/00 , A61B2562/06 , A61B5/01 , A61B5/036 , A61B5/0538 , A61B5/1032 , A61B5/11 , A61B5/14503 , A61B5/14507 , A61B5/14539 , A61B5/14542 , A61B5/14546 , A61B5/201 , A61B5/202 , A61B5/204 , A61B5/205 , A61B5/208 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6874 , A61L29/041 , A61L29/085 , A61L29/14 , A61M2025/0004 , A61M25/0017 , A61M25/0147
摘要： In some examples, a device includes a catheter insert elongated body defining a body lumen, the catheter insert elongated body being configured to be at least partially inserted to a catheter lumen defined by a catheter without covering a first fluid opening of the catheter and to form a fluidically tight coupling with the catheter, and one or more sensors positioned on the elongated body. At least one of the one or more sensors are configured to sense a substance of interest. The catheter insert elongated body includes a material that is a substantially non-permeable to the substance of interest.

10. 发明申请

WO2021133610A1 CATHETER INCLUDING A PLURALITY OF SENSORS 审中-公开
公开(公告)号：WO2021133610A1
公开(公告)日：2021-07-01
申请号：PCT/US2020/065353
申请日：2020-12-16
申请人： COVIDIEN LP
发明人： MILLER, David J.
IPC分类号： A61B5/00 , A61B5/20 , A61B2562/06 , A61B5/01 , A61B5/036 , A61B5/0538 , A61B5/1032 , A61B5/11 , A61B5/14503 , A61B5/14507 , A61B5/14539 , A61B5/14542 , A61B5/14546 , A61B5/201 , A61B5/202 , A61B5/204 , A61B5/205 , A61B5/208 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6874 , A61L29/041 , A61L29/085 , A61L29/14 , A61M2025/0004 , A61M25/0017 , A61M25/0147
摘要： In some examples, a medical device includes an elongated body defining an inner lumen. The medical device further includes an anchoring member and a first sensor at a proximal portion of the elongated body, and a second sensor at a distal portion of the elongated body or distal to a distal end of the elongated body. The second sensor is configured to sense a substance of interest and the elongated body comprises a material that is a substantially non-permeable to the substance of interest.

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