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1. 发明授权

US06280441B1 Apparatus and method for RF lesioning 失效
公开(公告)号：US06280441B1
公开(公告)日：2001-08-28
申请号：US08990377
申请日：1997-12-15
申请人： Thomas Patrick Ryan
发明人： Thomas Patrick Ryan
IPC分类号： A61B1736
CPC分类号： A61B18/148 , A61B2017/00026 , A61B2018/00023 , A61B2018/00702 , A61B2018/00875 , A61B2018/1435
摘要： To ablate target tissue a handle with proximal and distal ends connect to an interior passageway and along an axis. A semi rigid and helical effector at the distal end is along the axis and has a sharpened distal tip and a mount at its handle attachment. A source of radio frequency current supplies the effector and is insulated from the handle for delivery to bipolar and monopolar circuits. A return electrode connects between tissue and the source of radio frequency current. A sensor is carried on the handle positioned to measure target tissue ablation. A control couples the source of radio frequency current and the sensor for loop regulation of ablation. The effector is a wire bent into the helical shape with an insulating sleeve to prevent passage of radio frequency current near its mount. The sensor has a calculator to find impedance or temperature changes and the control examines for a rise. The effector is in an alternate a hollow tube bent into the helical shape and closed at its distal tip; the handle has a passage for fluid circulation. A return located on the effector insulating sleeve has a larger surface area than the distal tip. A bipolar delivery effector carries at least two electrodes supplied with current of opposite polarity between the electrodes. The effector is a framework with at least two supports for locating electrodes in spaced apart relationship about the distal tip. A plurality of electrodes are in an alternate coupled to the source of radio frequency current to receive opposite polarity from a multiplexer coupled electrically between the source of radio frequency current and the plurality of electrodes for selective delivery of radio frequency current of opposite polarity to at least two of the electrodes at the same time. An elongate shank extending from the mount to the helical shaped part of the effector for laparoscopic applications. A portal near the distal tip diverts the sensor to a position to measure target tissue. A light based system has a fiber optic for measurement of radiation of the target tissue with a meter. The control has a power modulator to maintain the impedance at approximately its low point. A method of ablating subsurface tissue includes inserting the distal tip into an entry point, rotating the effector about its axis to screw the helical shape into the tissue, and delivering controlled amounts of radio frequency current to the tissue.

2. 发明授权

US06231568B1 Channel-forming laser energy device 失效
标题翻译：通道形成激光能量装置
公开(公告)号：US06231568B1
公开(公告)日：2001-05-15
申请号：US09307512
申请日：1999-05-07
申请人： Marvin P. Loeb , L. Dean Crawford , Samuel M. Shaolian
发明人： Marvin P. Loeb , L. Dean Crawford , Samuel M. Shaolian
IPC分类号： A61B1736
CPC分类号： A61B18/24 , A61B2017/00199 , A61B2017/00247 , A61B2017/22075 , A61B2017/22077 , A61B2018/00392 , A61B2090/033
摘要： A surgical device is provided for forming a channel through or partially through vascular tissue, including vascular tissue, utilizing both mechanical and laser energy, and, if desired, depositing a therapeutic agent therein. The device includes an optical fiber for transmission of laser energy, a housing, and a hollow guide attached to the housing through which the optical fiber extends. A needle is attached to the distal end of the optical fiber in fluid communication with a catheter surrounding the optical fiber. Additionally, an actuator is included operably connected to the optical fiber for selectively extending the needle and/or fiber from the hollow guide. Finally, a laser control device is contemplated operably connected to the optical fiber, transmitting laser energy from the distal end of the fiber after the needle has penetrated a layer of selected distance into the tissue.
摘要翻译：提供了一种手术装置，用于通过或部分穿过血管组织（包括血管组织），利用机械和激光能量以及如果需要在其中沉积治疗剂。该装置包括用于传输激光能量的光纤，壳体和附接到壳体的中空导轨，光纤延伸穿过该壳体。针与光纤的远端连接，与光纤周围的导管流体连通。另外，包括可操作地连接到光纤的致动器，用于从中空引导件选择性地延伸针和/或纤维。最后，设想可操作地连接到光纤的激光控制装置，在针已经穿过选定距离的层到组织中之后，从光纤的远端传送激光能量。

3. 发明授权

US06786902B1 Method and apparatus for cryosurgery 失效
标题翻译：冷冻手术的方法和装置
公开(公告)号：US06786902B1
公开(公告)日：2004-09-07
申请号：US09527491
申请日：2000-03-16
申请人： Yoed Rabin , Thomas Benjamin Julian , Norman Wolmark
发明人： Yoed Rabin , Thomas Benjamin Julian , Norman Wolmark
IPC分类号： A61B1736
CPC分类号： A61B18/02 , A61B90/17 , A61B2018/0293
摘要： The present invention pertains to an apparatus for cryosurgery. The apparatus comprises a cryoneedle having a diameter less than 3.2 mm. The apparatus is also comprised of a thermal insulation shell disposed about a portion of the cryoneedle for reduction of heat transfer from surrounding tissues or freezing prevention of surrounding tissues during application of the cryoneedle with the shell. The cryoneedle and shell are configured for insertion into a body of a patient. The present invention pertains to a method for freezing tissues. The method comprises the steps of bringing into contact a cryoneedle having a diameter of less than 3.2 mm with a patient's body. Next, there is the step of flowing the cryofluid through the cryoneedle.
摘要翻译：本发明涉及一种用于冷冻手术的装置。该装置包括直径小于3.2mm的冷冻针。该装置还包括设置在冷冻针的一部分周围的绝热外壳，用于减少来自周围组织的热量传递或在与壳体一起使用冷冻食品时冻结周围组织的预防。冷冻针和外壳被配置成插入到患者体内。本发明涉及一种冷冻组织的方法。该方法包括使具有小于3.2mm直径的冷冻针与患者身体接触的步骤。接下来，有一个步骤是使冷冻液流过冷冻针。

4. 发明授权

US06692488B2 Apparatus for cell necrosis 有权
标题翻译：细胞坏死的装置
公开(公告)号：US06692488B2
公开(公告)日：2004-02-17
申请号：US09834068
申请日：2001-04-12
申请人： John D. Dobak, III , Juan C. Lasheras
发明人： John D. Dobak, III , Juan C. Lasheras
IPC分类号： A61B1736
CPC分类号： A61F7/12 , A61B2018/0212 , A61B2018/0262 , A61F2007/0056 , A61F2007/126
摘要： A heat transfer device has first and second elongated, articulated segments, each having a turbulence-inducing exterior surface. A flexible joint connects the first and second elongated, articulated segments. An inner coaxial lumen is disposed within the first and second elongated, articulated segments. The inner coaxial lumen is capable of transporting a pressurized working fluid to a distal end of the first elongated, articulated segment
摘要翻译：传热装置具有第一和第二细长的铰接段，每个段具有湍流诱导外表面。柔性接头连接第一和第二细长铰接段。内部同轴的内腔设置在第一和第二细长的关节部分内。内同轴内腔能够将加压工作流体输送到第一细长铰接段的远端

5. 发明授权

US06251100B1 Laser assisted topical anesthetic permeation 失效
标题翻译：激光辅助局部麻醉剂渗透
公开(公告)号：US06251100B1
公开(公告)日：2001-06-26
申请号：US08955545
申请日：1997-10-22
申请人： Stephen T. Flock , Kevin S. Marchitto , Charles H. Vestal , Paul A. Lehman
发明人： Stephen T. Flock , Kevin S. Marchitto , Charles H. Vestal , Paul A. Lehman
IPC分类号： A61B1736
CPC分类号： A61B18/20 , A61B5/150022 , A61B5/150076 , A61B5/150099 , A61B5/15138 , A61B5/411 , A61B17/3476 , A61B18/203 , A61B2010/008 , A61B2017/00057 , A61B2017/00765 , A61B2018/00452 , A61B2090/395 , A61B2218/008 , A61M37/00 , A61M2037/0007 , H04R25/75
摘要： The present invention provides an improved method of administering a pharmaceutical composition, such as an anesthetic through the skin of a patient without the use of a sharp or needle. This method includes the step of irradiating the stratum corneum of a region of the skin of the patient using a laser. By a selection of parameters, the laser irradiates the surface of the skin precisely to a selectable depth, without causing clinically relevant damage to healthy proximal tissue. A pharmaceutical composition is then applied to the region of irradiation.
摘要翻译：本发明提供了一种通过患者的皮肤给药药物组合物例如麻醉剂而不使用尖锐或针刺的改进方法。该方法包括使用激光照射患者皮肤区域的角质层的步骤。通过选择参数，激光将皮肤表面精确地照射到可选择的深度，而不会对健康的近端组织造成临床相关的损伤。然后将药物组合物施加到照射区域。

6. 发明授权

US06213999B1 Surgical gas plasma ignition apparatus and method 失效
标题翻译：手术气体等离子体点火装置及方法
公开(公告)号：US06213999B1
公开(公告)日：2001-04-10
申请号：US08934843
申请日：1997-09-22
申请人： Robert C. Platt, Jr. , Robin Badih Bek
发明人： Robert C. Platt, Jr. , Robin Badih Bek
IPC分类号： A61B1736
CPC分类号： A61B18/042 , A61B2018/1213
摘要： An apparatus and method for igniting plasma in a surgical system is disclosed. A corona discharge is generated on a surgical handpiece which is used to ignite a plasma arc for surgical operations. The advantages include greater reliability and repeatability of plasma arc ignition. The apparatus comprises a handpiece incorporating an active electrode, a passage for ionizable gas, and a corona return electrode. The corona return electrode has a terminus on the holder and near the distal end of the holder. The corona return electrode is electrically connected to the return path of the electrosurgical generator. A non-uniform electric field is generated between the active electrode and the corona return electrode of sufficient strength so that a corona is formed near the active electrode. A separate return electrode may be on the patient, or the apparatus may be configured for bipolar electrosurgical operation by carrying the return electrode on the handpiece. A dielectric material separates the active electrode and the corona return electrode. There is substantially capacitive coupling between the active electrode and the corona return electrode. There is substantially resistive coupling between the active electrode and the return electrode.
摘要翻译：公开了一种在外科手术系统中点燃血浆的装置和方法。在用于点燃用于外科手术的等离子体电弧的手术机身上产生电晕放电。优点包括提高等离子弧点火的可靠性和重复性。该装置包括结合有活性电极的手柄，可电离气体的通道和电晕返回电极。电晕返回电极在支架上具有一个末端，靠近支架的远端。电晕返回电极电连接到电外科发生器的返回路径。在有效电极和电晕返回电极之间产生足够强度的不均匀电场，使得在有源电极附近形成电晕。单独的返回电极可以在患者身上，或者该装置可以被配置为通过在手持件上携带返回电极来进行双极电外科操作。电介质材料分离有源电极和电晕返回电极。有源电极和电晕返回电极之间存在大体上的电容耦合。有源电极和返回电极之间存在大体上的电阻耦合。

7. 再颁专利

USRE38670E1 Apparatus for tissue treatment 有权
标题翻译：组织治疗装置
公开(公告)号：USRE38670E1
公开(公告)日：2004-12-14
申请号：US09973464
申请日：2001-10-11
申请人： Bjarne Asah , Olav Balle-Petersen
发明人： Bjarne Asah , Olav Balle-Petersen
IPC分类号： A61B1736
CPC分类号： A61N5/0616 , A61B18/20 , A61B18/203 , A61B2017/00057 , A61B2017/00747 , A61B2018/00452 , A61B2018/00458 , A61B2018/0047 , A61B2018/00476 , A61B2018/00904 , A61B2018/2025 , A61B2018/20359 , A61B2090/373 , A61N5/0617 , A61N2005/0644
摘要： An apparatus for tissue treatment is provided, comprising a light emitter for emission of a first light beam, director for directing the first light beam towards a target area to be treated, detector for detecting at least one tissue parameter at the target area, and first light beam controller for controlling at least one parameter without interruption of the propagating light beam. The tissue parameter may be selected from the group of texture, elasticity, size and shape. The apparatus may be used for ablating a thin epidermal layer of the derma of a patient and also marks on the tissue such as marks from chloasma, liver spots, red spots, tattoos, blood vessels just below the surface, etc. as well as warts, wounds, hair follicles, etc. may be ablated or treated.

8. 发明授权

US06565558B1 High-frequency device for generating a plasma arc for the treatment of biological tissue 有权
标题翻译：用于产生用于治疗生物组织的等离子弧的高频装置
公开(公告)号：US06565558B1
公开(公告)日：2003-05-20
申请号：US09763937
申请日：2001-02-27
申请人： Heinz Lindenmeier , Karl Fastenmeier
发明人： Heinz Lindenmeier , Karl Fastenmeier
IPC分类号： A61B1736
CPC分类号： A61B18/042 , H05H1/46 , H05H2001/466 , H05H2001/4682 , H05H2245/122
摘要： High-frequency device to generate a plasma arc (5) for the treatment of biological tissue (1), in particular in medicine, with a high-frequency generator (3) having an internal resistor (8) and, connected thereto by means of a flexible lead (10), an electrode (4) with which the plasma arc (5) is produced in a plasma segment (6) between the electrode (4) and the biological tissue (1), which is likewise electrically connected to the high-frequency generator (3), such that in the high-frequency generator (3) a high-frequency voltage source (7) is provided to which is connected a resonant circuit (2) that comprises a first reactance element (9a) with a capacitive action and, in series therewith, a second reactance element (9a) with an inductive action, and that has a resonant frequency at the frequency of the high-frequency oscillation emitted by the high-frequency voltage source (7), wherein the voltage to generate the plasma arc (5) is derived from the first or second reactance element (9a, 9b).
摘要翻译：用于产生用于处理生物组织（1），特别是医学中的等离子弧（5）的高频装置与具有内部电阻器（8）的高频发生器（3）连接，并且通过柔性引线（10），在电极（4）和生物组织（1）之间的等离子体段（6）中产生等离子弧（5）的电极（4），其同样电连接到高频发生器（3），使得在高频发生器（3）中，提供高频电压源（7），其连接有包括第一电抗元件（9a）的谐振电路（2）电容性动作，并且与其串联具有感应作用的第二电抗元件（9a），并且在由高频电压源（7）发射的高频振荡的频率处具有谐振频率，其中，产生等离子弧（5）的电压从第一或第二电抗元件（ 9a，9b）。

9. 发明授权

US06428553B1 Illuminated ophthalmic membrane pick assembly 有权
标题翻译：照明眼科膜组件
公开(公告)号：US06428553B1
公开(公告)日：2002-08-06
申请号：US09520913
申请日：2000-03-08
申请人： Michael T. Trese
发明人： Michael T. Trese
IPC分类号： A61B1736
CPC分类号： A61F9/00736 , A61B3/0008 , A61B2090/306
摘要： An illuminated ophthalmic membrane pick assembly is disclosed having an elongated housing and a throughbore extending between the housing ends. An elongated tubular probe has one end secured to one end of the housing in alignment with the housing throughbore. A membrane pick is secured to the other or free end of the probe so that a free end of the membrane pick overlies the free end of the probe. An optical fiber is longitudinally slidably disposed through the housing throughbore and the probe while a button mechanically secured to the optical fiber and slidably mounted to the housing moves the optical fiber between an extended and a retracted position. In its extended position, the optical fiber laterally outwardly displaces the membrane pick so that the free end of the pick abuts against a side of the optical fiber. Conversely, in its retracted position, the optical fiber is nested within the probe.
摘要翻译：公开了一种照明的眼科膜拾取组件，其具有细长壳体和在壳体端部之间延伸的通孔。细长的管状探针的一端固定到壳体的一端，与壳体通孔对准。膜片固定到探针的另一个或自由端，使得膜拾取物的自由端覆盖探针的自由端。光纤通过壳体通孔和探头纵向可滑动地设置，而机械地固定到光纤上并且可滑动地安装到壳体的按钮将光纤延伸到延伸位置和缩回位置之间。在其延伸位置，光纤横向向外移位膜拾取器，使得拾取器的自由端抵靠光纤的一侧。相反，在其缩回位置，光纤被嵌套在探针内。

10. 发明授权

US06352549B1 Medical device for applying high energy light and heat for gynecological sterilization procedures 失效
标题翻译：用于妇科消毒手术的高能量光热医疗装置
公开(公告)号：US06352549B1
公开(公告)日：2002-03-05
申请号：US08592006
申请日：1996-01-26
申请人： Royice B. Everett
发明人： Royice B. Everett
IPC分类号： A61B1736
CPC分类号： A61B18/24 , A61B2017/0007 , A61B2017/00084 , A61B2017/4233
摘要： A localized heat applying medical device is provided for applying heat to tissue adjacent a patient's tubal ostia in order to close the patient's fallopian tubes and sterilize the patient. Procedures of performing sterilizations are also disclosed.
摘要翻译：提供局部加热的医疗装置用于对患者输卵管口附近的组织施加热量，以封闭患者的输卵管并对患者消毒。还公开了进行灭菌的程序。

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